Should blood transfusion be individualised? We are not sure

Intensive Care Medicine

Volumn 41, Issue 11, 2015, Pages 1980-1982

  Docherty, Annemarie ^a,b   Walsh, Timothy S ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

ACCURACY; BLOOD TRANSFUSION; CRITICALLY ILL PATIENT; EDITORIAL; ERYTHROCYTE TRANSFUSION; HEMOGLOBIN DETERMINATION; HUMAN; MICROCIRCULATION; MORBIDITY; MORTALITY; OXYGEN SUPPLY; PERSONALIZED MEDICINE; CARDIOVASCULAR DISEASES; COMORBIDITY; COST BENEFIT ANALYSIS; CRITICAL ILLNESS; ECONOMICS; EVIDENCE BASED PRACTICE; HIP; INTENSIVE CARE; OUTCOME ASSESSMENT; PHYSIOLOGY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEPSIS; SEVERITY OF ILLNESS INDEX; STANDARDS; STATISTICS AND NUMERICAL DATA; SURGERY;

BLOOD TRANSFUSION; CARDIOVASCULAR DISEASES; COMORBIDITY; COST-BENEFIT ANALYSIS; CRITICAL CARE; CRITICAL ILLNESS; EVIDENCE-BASED PRACTICE; HEMOGLOBINS; HIP; HUMANS; OUTCOME ASSESSMENT (HEALTH CARE); PRECISION MEDICINE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 84942500275     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-015-4034-4     Document Type: Editorial

References (15)

1. Hebert PC, Wells G, Blajchman M et al (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340:409–417
2. Holst LB, Haase N, Wetterslev J et al (2014) Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med 371:1381–1391. doi:10.1056/NEJMoa1406617
3. SHOT Steering Group (2013) Annual SHOT report 2013. SHOT, Manchester
4. Ostermann M, Lo J, Toolan M et al (2014) A prospective study of the impact of serial troponin measurements on the diagnosis of myocardial infarction and hospital and six-month mortality in patients admitted to ICU with non-cardiac diagnoses. Crit Care 18:R62. doi:10.1186/cc13818
5. Lim W, Qushmaq I, Deveraux P et al (2006) Elevated cardiac troponin measurements in critically Ill patients. J Am Med Assoc 166:2446–2454
6. 2 extraction in sepsis. Am J Physiol Heart Circ Physiol 282:H156–H164
7. Ince C, Sinaasappel M (1999) Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 27:1369–1377
8. Yuruk K, Almac E, Bezemer R et al (2011) Blood transfusions recruit the microcirculation during cardiac surgery. Transfusion 51:961–967
9. Carson J, Terrin M, Noveck H et al (2011) Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med 365:2453–2462
10. Walsh TS, Boyd JA, Watson D et al (2013) Restrictive versus liberal transfusion strategies for older mechanically ventilated critically ill patients: a randomized pilot trial. Crit Care Med 41:2354–2363. doi:10.1097/CCM.0b013e318291cce4
11. Angus DC, Barnato AE, Bell D et al (2015) A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med. doi:10.1007/s00134-015-3822-1
12. Deans K, Minneci P, Suffredini A et al (2007) Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols. Crit Care Med 35:1509–1516
13. Bateman A, McArdle F, Walsh T (2009) Time course of anemia during six months follow up following intensive care discharge and factors associated with impaired recovery of erythropoiesis. Crit Care Med 37:1906–1912
14. Jansen A, Essink-Bot M, Beckers E et al (2003) Quality of life measurement in patients with transfusion-dependent myelodysplastic syndromes. Br J Haematol 121:270–274
15. Wilton K, Fowler R, Walsh T et al (2014) Variation in red blood cell transfusion thresholds in critically ill patients. Crit Care 18:106