The blood transcriptome of experimental melioidosis reflects disease severity and shows considerable similarity with the human disease

Journal of Immunology

Volumn 195, Issue 7, 2015, Pages 3248-3261

  Conejero, Laura ^a,i   Potempa, Krzysztof ^b   Graham, Christine M ^b   Spink, Natasha ^a   Blankley, Simon ^b   Salguero, Francisco J ^c   Pankla Sranujit, Rungnapa ^d   Khaenam, Prasong ^d   Banchereau, Jacques F ^e   Pascual, Virginia ^f   Chaussabel, Damien ^g   Lertmemongkolchai, Ganjana ^d   O'Garra, Anne ^b,h   Bancroft, Gregory J ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c UNIVERSITY OF SURREY   (United Kingdom)

^d KHON KAEN UNIVERSITY   (Thailand)

^e JACKSON LABORATORY   (United States)

^f BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^g SIDRA MEDICAL AND RESEARCH CENTER   (Qatar)

^h ST MARY S HOSPITAL   (United Kingdom)

ⁱ CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; COLLAGEN; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON; INTERLEUKIN 10; MATRIX METALLOPROTEINASE; TRANSCRIPTOME; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; ARG2 PROTEIN, MOUSE; ARGINASE; GAMMA INTERFERON; GELATINASE B; IL10 PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; MMP9 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; TREM1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; FEMALE; FIBROSIS; HUMAN; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFECTION; INNATE IMMUNITY; MELIOIDOSIS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SEPTICEMIA; T LYMPHOCYTE; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; LUNG; MICROBIOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ARGINASE; BURKHOLDERIA PSEUDOMALLEI; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-10; LUNG; MATRIX METALLOPROTEINASE 9; MELIOIDOSIS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84942475224     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500641     Document Type: Article

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