Mature cystic fibrosis airway neutrophils suppress T cell function: Evidence for a role of arginase 1 but not programmed death-ligand 1

Journal of Immunology

Volumn 194, Issue 11, 2015, Pages 5520-5528

  Ingersoll, Sarah A ^a,b   Laval, Julie ^a,b   Forrest, Osric A ^a,b   Preininger, Marcela ^a,b   Brown, Milton R ^a,b   Arafat, Dalia ^c   Gibson, Greg ^c   Tangpricha, Vin ^a   Tirouvanziam, Rabindra ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; ARGINASE INHIBITOR; ARGININE; ENZYME INHIBITOR; PROGRAMMED DEATH 1 LIGAND 1; UNCLASSIFIED DRUG; ARGINASE; ARGINASE I, HUMAN; CD274 PROTEIN, HUMAN;

ADULT; AIRWAY; ARTICLE; CELL SUBPOPULATION; CLINICAL ARTICLE; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTIC FIBROSIS; CYSTIC FIBROSIS AIRWAY NEUTROPHIL; ENZYME ACTIVATION; ENZYME ACTIVITY; EXOCYTOSIS; FEMALE; HUMAN; IMMUNOREGULATION; LUNG FUNCTION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MALE; MIDDLE AGED; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL GRANULE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; YOUNG ADULT; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; IMMUNOLOGY; INFLAMMATION; LUNG; LUNG FUNCTION TEST; LYMPHOCYTE ACTIVATION; PATHOLOGY; RESPIRATORY TRACT MUCOSA;

ADULT; ANTIGENS, CD274; APOPTOSIS; ARGINASE; CELL PROLIFERATION; CYSTIC FIBROSIS; EXOCYTOSIS; FEMALE; HUMANS; INFLAMMATION; LUNG; LYMPHOCYTE ACTIVATION; MALE; NEUTROPHILS; RESPIRATORY FUNCTION TESTS; RESPIRATORY MUCOSA; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84929612761     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500312     Document Type: Article

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