메뉴 건너뛰기




Volumn 7, Issue 1, 2015, Pages

Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

Author keywords

Alternative splicing; Differences in drug metabolism; DNA methylation mapping; Integrative analysis

Indexed keywords

DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE 1A1; MESSENGER RNA;

EID: 84942465814     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-015-0136-7     Document Type: Article
Times cited : (45)

References (30)
  • 1
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science. 1999;286:487-91.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 3
    • 84855953171 scopus 로고    scopus 로고
    • PharmGKB summary: Very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19
    • Scott SA, Sangkuhl K, Shuldiner AR, Hulotn J-S, Thorn CF, Altman RB, et al. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19. Pharmacogenet Genomics. 2012;22:159-65.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 159-165
    • Scott, S.A.1    Sangkuhl, K.2    Shuldiner, A.R.3    Hulotn, J.-S.4    Thorn, C.F.5    Altman, R.B.6
  • 5
    • 0028237729 scopus 로고
    • Inter-individual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich P. Inter-individual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther. 1994;270:414-23.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, P.5
  • 6
  • 7
    • 34250202527 scopus 로고    scopus 로고
    • Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: Roles of UGT1A1*6 and *28
    • Minami H, Sai K, Saeki M, Saito Y, Ozawa S, Suzuki K, et al. Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28. Pharmacogenet Genomics. 2007;17:497-504.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 497-504
    • Minami, H.1    Sai, K.2    Saeki, M.3    Saito, Y.4    Ozawa, S.5    Suzuki, K.6
  • 8
    • 2942527225 scopus 로고    scopus 로고
    • UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
    • Sai K, Saeki M, Saito Y, Ozawa S, Katori N, Jinno H, et al. UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clin Pharmacol Ther. 2004;75:501-15.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 501-515
    • Sai, K.1    Saeki, M.2    Saito, Y.3    Ozawa, S.4    Katori, N.5    Jinno, H.6
  • 9
    • 84908159566 scopus 로고    scopus 로고
    • Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer
    • Li M, Wang Z, Guo J, Liu J, Li C, Liu L, et al. Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer. Onco Targets Ther. 2014;7:1653-61.
    • (2014) Onco Targets Ther , vol.7 , pp. 1653-1661
    • Li, M.1    Wang, Z.2    Guo, J.3    Liu, J.4    Li, C.5    Liu, L.6
  • 10
    • 47949110575 scopus 로고    scopus 로고
    • Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines
    • Nakamura A, Nakajima M, Yamanaka H, Fujiwara R, Yokoi T. Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines. Drug Metab Dispos. 2008;36:1461-4.
    • (2008) Drug Metab Dispos , vol.36 , pp. 1461-1464
    • Nakamura, A.1    Nakajima, M.2    Yamanaka, H.3    Fujiwara, R.4    Yokoi, T.5
  • 11
    • 0036150897 scopus 로고    scopus 로고
    • Developmental aspects of human hepatic drug glucuronidation in young children and adults
    • Strassburg CP, Strassburg A, Kneip S, Barut A, Tukey RH, Rodeck B, et al. Developmental aspects of human hepatic drug glucuronidation in young children and adults. Gut. 2002;50:259-65.
    • (2002) Gut , vol.50 , pp. 259-265
    • Strassburg, C.P.1    Strassburg, A.2    Kneip, S.3    Barut, A.4    Tukey, R.H.5    Rodeck, B.6
  • 12
    • 0034128936 scopus 로고    scopus 로고
    • Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
    • Tukey RH, Strassburg CP. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu Rev Pharmacol Toxicol. 2000;40:581-616.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 581-616
    • Tukey, R.H.1    Strassburg, C.P.2
  • 13
    • 67649419039 scopus 로고    scopus 로고
    • CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers
    • Habano W, Gamo T, Sugai T, Otsuka K, Wakabayashi G, Ozawa S. CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. Int J Oncol. 2009;34:1085-91.
    • (2009) Int J Oncol , vol.34 , pp. 1085-1091
    • Habano, W.1    Gamo, T.2    Sugai, T.3    Otsuka, K.4    Wakabayashi, G.5    Ozawa, S.6
  • 14
    • 79951777299 scopus 로고    scopus 로고
    • Involvement of promoter methylation in the regulation of pregnane X receptor in colon cancer cells
    • Habano W, Gamo T, Terashima J, Sugai T, Otsuka K, Wakabayashi G, et al. Involvement of promoter methylation in the regulation of pregnane X receptor in colon cancer cells. BMC Cancer. 2011;11:81.
    • (2011) BMC Cancer , vol.11 , pp. 81
    • Habano, W.1    Gamo, T.2    Terashima, J.3    Sugai, T.4    Otsuka, K.5    Wakabayashi, G.6
  • 15
    • 84898051723 scopus 로고    scopus 로고
    • Epigenetic changes in gene expression for drug-metabolizing enzymes and transporters
    • Kim IW, Han N, Burckart GJ, Oh JM. Epigenetic changes in gene expression for drug-metabolizing enzymes and transporters. Pharmacotherapy. 2014;34:140-50.
    • (2014) Pharmacotherapy , vol.34 , pp. 140-150
    • Kim, I.W.1    Han, N.2    Burckart, G.J.3    Oh, J.M.4
  • 16
  • 18
    • 79955778919 scopus 로고    scopus 로고
    • Human epigenome data reveal increased CpG methylation in alternatively spliced sites and putative exonic splicing enhancers
    • Anastasiadou C, Malousi A, Maglaveras N, Kouidou S. Human epigenome data reveal increased CpG methylation in alternatively spliced sites and putative exonic splicing enhancers. DNA Cell Biol. 2011;30:267-75.
    • (2011) DNA Cell Biol , vol.30 , pp. 267-275
    • Anastasiadou, C.1    Malousi, A.2    Maglaveras, N.3    Kouidou, S.4
  • 19
    • 84988935069 scopus 로고    scopus 로고
    • Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression
    • Edgar R, Tan PP, Portales-Casamar E, Pavlidis P. Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression. Epingenetics Chromatin. 2014;7:28.
    • (2014) Epingenetics Chromatin , vol.7 , pp. 28
    • Edgar, R.1    Tan, P.P.2    Portales-Casamar, E.3    Pavlidis, P.4
  • 20
    • 34547899883 scopus 로고    scopus 로고
    • Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
    • Bièche I, Narjoz C, Asselah T, Vacher S, Marcellin P, Lidereau R, et al. Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues. Pharmacogenet Genomics. 2007;17:731-42.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 731-742
    • Bièche, I.1    Narjoz, C.2    Asselah, T.3    Vacher, S.4    Marcellin, P.5    Lidereau, R.6
  • 21
    • 84881319858 scopus 로고    scopus 로고
    • DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery
    • Ahrens M, Ammerpohl O, von Schönfels W, Kolarova J, Bens S, Itzel T, et al. DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery. Cell Metab. 2013;18:296-302.
    • (2013) Cell Metab , vol.18 , pp. 296-302
    • Ahrens, M.1    Ammerpohl, O.2    Von Schönfels, W.3    Kolarova, J.4    Bens, S.5    Itzel, T.6
  • 22
    • 83455237886 scopus 로고    scopus 로고
    • Batch effect correction for genome-wide methylation data with Illumina Infinium platform
    • Sun Z, Chai HS, Wu Y, White WM, Donkena KV, Klein CJ, et al. Batch effect correction for genome-wide methylation data with Illumina Infinium platform. BMC Med Genomics. 2011;4:84.
    • (2011) BMC Med Genomics , vol.4 , pp. 84
    • Sun, Z.1    Chai, H.S.2    Wu, Y.3    White, W.M.4    Donkena, K.V.5    Klein, C.J.6
  • 23
    • 84883156126 scopus 로고    scopus 로고
    • Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function
    • Ivanov M, Kals M, Kacevska M, Barragan I, Kasuga K, Rane A, et al. Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function. Genome Biol. 2013;14:R83.
    • (2013) Genome Biol , vol.14
    • Ivanov, M.1    Kals, M.2    Kacevska, M.3    Barragan, I.4    Kasuga, K.5    Rane, A.6
  • 24
  • 25
    • 77954171220 scopus 로고    scopus 로고
    • Contrasting chromatin organization of CpG islands and exons in the human genome
    • Choi JK. Contrasting chromatin organization of CpG islands and exons in the human genome. Genome Biol. 2010;11:R70.
    • (2010) Genome Biol , vol.11
    • Choi, J.K.1
  • 26
    • 84877108379 scopus 로고    scopus 로고
    • DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure
    • Gelfman S, Cohen N, Yearim A, Ast G. DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure. Genome Res. 2013;23:789-99.
    • (2013) Genome Res , vol.23 , pp. 789-799
    • Gelfman, S.1    Cohen, N.2    Yearim, A.3    Ast, G.4
  • 27
    • 84893729914 scopus 로고    scopus 로고
    • Epigenetic regulation of the tissue-specific expression of human UDP-glucuronosyltransferase (UGT) 1A10
    • Oda S, Fukami T, Yokoi T, Nakajima M. Epigenetic regulation of the tissue-specific expression of human UDP-glucuronosyltransferase (UGT) 1A10. Biochem Pharmacol. 2014;87:660-7.
    • (2014) Biochem Pharmacol , vol.87 , pp. 660-667
    • Oda, S.1    Fukami, T.2    Yokoi, T.3    Nakajima, M.4
  • 28
    • 69949190951 scopus 로고    scopus 로고
    • Functional analysis of GC Box and its CpG methylation in the regulation of CYP1A2 gene expression
    • Miyajima A, Furihata T, Chiba K. Functional analysis of GC Box and its CpG methylation in the regulation of CYP1A2 gene expression. Drug Metab Pharmacokinet. 2009;24:269-76.
    • (2009) Drug Metab Pharmacokinet , vol.24 , pp. 269-276
    • Miyajima, A.1    Furihata, T.2    Chiba, K.3
  • 29
    • 80053304450 scopus 로고    scopus 로고
    • High density DNA methylation array with single CpG site resolution
    • Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM, et al. High density DNA methylation array with single CpG site resolution. Genomics. 2011;98:288-95.
    • (2011) Genomics , vol.98 , pp. 288-295
    • Bibikova, M.1    Barnes, B.2    Tsan, C.3    Ho, V.4    Klotzle, B.5    Le, J.M.6
  • 30
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 1997;25:2532-4.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.