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Volumn 126, Issue 11, 2015, Pages 1302-1313

Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation

Author keywords

[No Author keywords available]

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 3; EGR3 PROTEIN, MOUSE; MESSENGER RNA; RNA;

EID: 84942415177     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-01-623645     Document Type: Article
Times cited : (90)

References (38)
  • 1
    • 84868374023 scopus 로고    scopus 로고
    • The transcriptional landscape of hematopoietic stem cell ontogeny
    • McKinney-Freeman S, Cahan P, Li H, et al. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 2012;11(5):701-714.
    • (2012) Cell Stem Cell , vol.11 , Issue.5 , pp. 701-714
    • McKinney-Freeman, S.1    Cahan, P.2    Li, H.3
  • 2
    • 84859172948 scopus 로고    scopus 로고
    • Deconstructing the complexity of a microenvironmental niche
    • Krause DS, Scadden DT. Deconstructing the complexity of a microenvironmental niche. Cell. 2012;149(1):16-17.
    • (2012) Cell , vol.149 , Issue.1 , pp. 16-17
    • Krause, D.S.1    Scadden, D.T.2
  • 3
    • 43749110075 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal
    • Zon LI. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature. 2008;453(7193):306-313.
    • (2008) Nature , vol.453 , Issue.7193 , pp. 306-313
    • Zon, L.I.1
  • 5
    • 78751582939 scopus 로고    scopus 로고
    • Hematopoietic stem cell: Self-renewal versus differentiation
    • Seita J, Weissman IL. Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med. 2010;2(6):640-653.
    • (2010) Wiley Interdiscip Rev Syst Biol Med , vol.2 , Issue.6 , pp. 640-653
    • Seita, J.1    Weissman, I.L.2
  • 6
    • 77649335651 scopus 로고    scopus 로고
    • Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells
    • Forsberg EC, Passegué E, Prohaska SS, et al. Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. PLoS One. 2010;5(1):e8785.
    • (2010) PLoS One , vol.5 , Issue.1
    • Forsberg, E.C.1    Passegué, E.2    Prohaska, S.S.3
  • 7
    • 70449700034 scopus 로고    scopus 로고
    • Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model
    • Hu X, Shen H, Tian C, et al. Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model. Blood. 2009;114(18):3783-3792.
    • (2009) Blood , vol.114 , Issue.18 , pp. 3783-3792
    • Hu, X.1    Shen, H.2    Tian, C.3
  • 8
    • 84882412558 scopus 로고    scopus 로고
    • Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation
    • Miraki-Moud F, Anjos-Afonso F, Hodby KA, et al. Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation. Proc Natl Acad Sci USA. 2013;110(33):13576-13581.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.33 , pp. 13576-13581
    • Miraki-Moud, F.1    Anjos-Afonso, F.2    Hodby, K.A.3
  • 9
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008;322(5909):1861-1865.
    • (2008) Science , vol.322 , Issue.5909 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 10
    • 84859832491 scopus 로고    scopus 로고
    • Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia
    • Zhang B, Ho YW, Huang Q, et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia. Cancer Cell. 2012;21(4):577-592.
    • (2012) Cancer Cell , vol.21 , Issue.4 , pp. 577-592
    • Zhang, B.1    Ho, Y.W.2    Huang, Q.3
  • 11
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
    • Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 2013;13(3):285-299.
    • (2013) Cell Stem Cell , vol.13 , Issue.3 , pp. 285-299
    • Schepers, K.1    Pietras, E.M.2    Reynaud, D.3
  • 12
    • 84859838762 scopus 로고    scopus 로고
    • An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic stem cells
    • Shen H, Yu H, Liang PH, et al. An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic stem cells. Blood. 2012;119(15):3629-3637.
    • (2012) Blood , vol.119 , Issue.15 , pp. 3629-3637
    • Shen, H.1    Yu, H.2    Liang, P.H.3
  • 13
    • 84880638316 scopus 로고    scopus 로고
    • Mouse hematopoietic stem cell transplantation
    • Cheng H, Liang PH, Cheng T. Mouse hematopoietic stem cell transplantation. Methods Mol Biol. 2013;976:25-35.
    • (2013) Methods Mol Biol , vol.976 , pp. 25-35
    • Cheng, H.1    Liang, P.H.2    Cheng, T.3
  • 14
    • 34548414281 scopus 로고    scopus 로고
    • Adult mouse hematopoietic stem cells: Purification and single-cell assays
    • Ema H, Morita Y, Yamazaki S, et al. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nat Protoc. 2006;1(6):2979-2987.
    • (2006) Nat Protoc , vol.1 , Issue.6 , pp. 2979-2987
    • Ema, H.1    Morita, Y.2    Yamazaki, S.3
  • 15
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 16
    • 8844250116 scopus 로고    scopus 로고
    • Molecular signatures of proliferation and quiescence in hematopoietic stem cells
    • Venezia TA, Merchant AA, Ramos CA, et al. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2004;2(10):e301.
    • (2004) PLoS Biol , vol.2 , Issue.10 , pp. e301
    • Venezia, T.A.1    Merchant, A.A.2    Ramos, C.A.3
  • 17
    • 33749440584 scopus 로고    scopus 로고
    • Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
    • Somervaille TC, Cleary ML. Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell. 2006;10(4):257-268.
    • (2006) Cancer Cell , vol.10 , Issue.4 , pp. 257-268
    • Somervaille, T.C.1    Cleary, M.L.2
  • 18
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science. 1996;273(5272):242-245.
    • (1996) Science , vol.273 , Issue.5272 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 19
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121(7):1109-1121.
    • (2005) Cell , vol.121 , Issue.7 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 20
    • 0034749999 scopus 로고    scopus 로고
    • Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(1)c-kit(1) stem cell compartment is accompanied by loss of self-renewal capacity
    • Adolfsson J, Borge OJ, Bryder D, et al. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(1)c-kit(1) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity. 2001;15(4):659-669.
    • (2001) Immunity , vol.15 , Issue.4 , pp. 659-669
    • Adolfsson, J.1    Borge, O.J.2    Bryder, D.3
  • 21
    • 15944363056 scopus 로고    scopus 로고
    • Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
    • Yang L, Bryder D, Adolfsson J, et al. Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood. 2005;105(7):2717-2723.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2717-2723
    • Yang, L.1    Bryder, D.2    Adolfsson, J.3
  • 22
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000;404(6774):193-197.
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 23
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell. 1997;91(5):661-672.
    • (1997) Cell , vol.91 , Issue.5 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 24
    • 41449118699 scopus 로고    scopus 로고
    • The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells
    • Min IM, Pietramaggiori G, Kim FS, Passegué E, Stevenson KE, Wagers AJ. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell. 2008;2(4):380-391.
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 380-391
    • Min, I.M.1    Pietramaggiori, G.2    Kim, F.S.3    Passegué, E.4    Stevenson, K.E.5    Wagers, A.J.6
  • 25
    • 0035283135 scopus 로고    scopus 로고
    • Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages
    • Krishnaraju K, Hoffman B, Liebermann DA. Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages. Blood. 2001;97(5):1298-1305.
    • (2001) Blood , vol.97 , Issue.5 , pp. 1298-1305
    • Krishnaraju, K.1    Hoffman, B.2    Liebermann, D.A.3
  • 26
    • 0037369237 scopus 로고    scopus 로고
    • HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo
    • Kunisato A, Chiba S, Nakagami-Yamaguchi E, et al. HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood. 2003;101(5):1777-1783.
    • (2003) Blood , vol.101 , Issue.5 , pp. 1777-1783
    • Kunisato, A.1    Chiba, S.2    Nakagami-Yamaguchi, E.3
  • 27
    • 84873619091 scopus 로고    scopus 로고
    • Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment
    • Tian C, Zheng G, Cao Z, et al. Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment. Cell Cycle. 2013;12(2):322-331.
    • (2013) Cell Cycle , vol.12 , Issue.2 , pp. 322-331
    • Tian, C.1    Zheng, G.2    Cao, Z.3
  • 28
    • 78649880379 scopus 로고    scopus 로고
    • The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells
    • Sirin O, Lukov GL, Mao R, Conneely OM, Goodell MA. The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol. 2010;12(12):1213-1219.
    • (2010) Nat Cell Biol , vol.12 , Issue.12 , pp. 1213-1219
    • Sirin, O.1    Lukov, G.L.2    Mao, R.3    Conneely, O.M.4    Goodell, M.A.5
  • 29
    • 18244375249 scopus 로고    scopus 로고
    • Egr-2 and Egr-3 are negative regulators of T cell activation
    • Safford M, Collins S, Lutz MA, et al. Egr-2 and Egr-3 are negative regulators of T cell activation. Nat Immunol. 2005;6(5):472-480.
    • (2005) Nat Immunol , vol.6 , Issue.5 , pp. 472-480
    • Safford, M.1    Collins, S.2    Lutz, M.A.3
  • 30
    • 84867876944 scopus 로고    scopus 로고
    • The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells
    • Li S, Miao T, Sebastian M, et al. The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells. Immunity. 2012;37(4):685-696.
    • (2012) Immunity , vol.37 , Issue.4 , pp. 685-696
    • Li, S.1    Miao, T.2    Sebastian, M.3
  • 31
    • 33744977004 scopus 로고    scopus 로고
    • Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals
    • Xi H, Schwartz R, Engel I, Murre C, Kersh GJ. Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. Immunity. 2006;24(6):813-826.
    • (2006) Immunity , vol.24 , Issue.6 , pp. 813-826
    • Xi, H.1    Schwartz, R.2    Engel, I.3    Murre, C.4    Kersh, G.J.5
  • 32
    • 1642495761 scopus 로고    scopus 로고
    • Early growth response gene 3 regulates thymocyte proliferation during the transition from CD4-CD8- to CD4+CD8+
    • Xi H, Kersh GJ. Early growth response gene 3 regulates thymocyte proliferation during the transition from CD4-CD8- to CD4+CD8+. J Immunol. 2004;172(2):964-971.
    • (2004) J Immunol , vol.172 , Issue.2 , pp. 964-971
    • Xi, H.1    Kersh, G.J.2
  • 33
    • 84920759900 scopus 로고    scopus 로고
    • Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen
    • Ma S, Shi Y, Pang Y, et al. Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen. J Hematol Oncol. 2014;7(1):71.
    • (2014) J Hematol Oncol , vol.7 , Issue.1 , pp. 71
    • Ma, S.1    Shi, Y.2    Pang, Y.3
  • 34
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
    • Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature. 2010;465(7299):793-797.
    • (2010) Nature , vol.465 , Issue.7299 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 35
    • 84903993535 scopus 로고    scopus 로고
    • Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner
    • Wang L, Zhang H, Rodriguez S, et al. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner. Cell Stem Cell. 2014;15(1):51-65.
    • (2014) Cell Stem Cell , vol.15 , Issue.1 , pp. 51-65
    • Wang, L.1    Zhang, H.2    Rodriguez, S.3
  • 36
    • 84905580119 scopus 로고    scopus 로고
    • Graft-versus-host disease causes broad suppression of hematopoietic primitive cells and blocks megakaryocyte differentiation in a murine model
    • Lin Y, Hu X, Cheng H, et al. Graft-versus-host disease causes broad suppression of hematopoietic primitive cells and blocks megakaryocyte differentiation in a murine model. Biol Blood Marrow Transplant. 2014;20(9):1290-1300.
    • (2014) Biol Blood Marrow Transplant , vol.20 , Issue.9 , pp. 1290-1300
    • Lin, Y.1    Hu, X.2    Cheng, H.3
  • 37
    • 0036081059 scopus 로고    scopus 로고
    • Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S
    • Na Nakorn T, Traver D, Weissman IL, Akashi K. Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest. 2002;109(12):1579-1585.
    • (2002) J Clin Invest , vol.109 , Issue.12 , pp. 1579-1585
    • Na Nakorn, T.1    Traver, D.2    Weissman, I.L.3    Akashi, K.4
  • 38
    • 84908125658 scopus 로고    scopus 로고
    • Clonal dynamics of native haematopoiesis
    • Sun J, Ramos A, Chapman B, et al. Clonal dynamics of native haematopoiesis. Nature. 2014;514(7522):322-327.
    • (2014) Nature , vol.514 , Issue.7522 , pp. 322-327
    • Sun, J.1    Ramos, A.2    Chapman, B.3


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