메뉴 건너뛰기




Volumn 168, Issue 1-2, 2015, Pages 421-428

Rare variants in the neurotrophin signaling pathway implicated in schizophrenia risk

Author keywords

ARMS; De novo; Exome sequencing; Kidins220; Neurotrophin; Rare variant; Schizophrenia; Sporadic

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 3 RECEPTOR; NEUROTROPHIN 4; NEUROTROPHIN RECEPTOR; NEUROTROPHIN RECEPTOR P75; PROTEIN TYROSINE KINASE A;

EID: 84942370996     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2015.07.002     Document Type: Article
Times cited : (27)

References (67)
  • 1
    • 17144446761 scopus 로고    scopus 로고
    • A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein
    • Arevalo J.C., Yano H., Teng K.K., Chao M.V. A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein. EMBO J. 2004, 23(12):2358-2368.
    • (2004) EMBO J. , vol.23 , Issue.12 , pp. 2358-2368
    • Arevalo, J.C.1    Yano, H.2    Teng, K.K.3    Chao, M.V.4
  • 4
    • 84867796651 scopus 로고    scopus 로고
    • Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling
    • Arons M.H., Thynne C.J., Grabrucker A.M., Li D., Schoen M., Cheyne J.E., Boeckers T.M., Montgomery J.M., Garner C.C. Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling. J. Neurosci. 2012, 32(43):14966-14978.
    • (2012) J. Neurosci. , vol.32 , Issue.43 , pp. 14966-14978
    • Arons, M.H.1    Thynne, C.J.2    Grabrucker, A.M.3    Li, D.4    Schoen, M.5    Cheyne, J.E.6    Boeckers, T.M.7    Montgomery, J.M.8    Garner, C.C.9
  • 6
    • 33846087314 scopus 로고    scopus 로고
    • Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation
    • Bracale A., Cesca F., Neubrand V.E., Newsome T.P., Way M., Schiavo G. Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation. Mol. Biol. Cell 2007, 18(1):142-152.
    • (2007) Mol. Biol. Cell , vol.18 , Issue.1 , pp. 142-152
    • Bracale, A.1    Cesca, F.2    Neubrand, V.E.3    Newsome, T.P.4    Way, M.5    Schiavo, G.6
  • 7
    • 0033847939 scopus 로고    scopus 로고
    • Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: the Early Trauma Inventory
    • Bremner J.D., Vermetten E., Mazure C.M. Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: the Early Trauma Inventory. Depress. Anxiety 2000, 12(1):1-12.
    • (2000) Depress. Anxiety , vol.12 , Issue.1 , pp. 1-12
    • Bremner, J.D.1    Vermetten, E.2    Mazure, C.M.3
  • 8
    • 84867744055 scopus 로고    scopus 로고
    • Differential BDNF signaling in dentate gyrus and perirhinal cortex during consolidation of recognition memory in the rat
    • Callaghan C.K., Kelly Á.M. Differential BDNF signaling in dentate gyrus and perirhinal cortex during consolidation of recognition memory in the rat. Hippocampus 2012, 22(11):2127-2135.
    • (2012) Hippocampus , vol.22 , Issue.11 , pp. 2127-2135
    • Callaghan, C.K.1    Kelly, Á.M.2
  • 9
    • 33745684557 scopus 로고    scopus 로고
    • Gene-environment interactions in psychiatry: joining forces with neuroscience
    • Caspi A., Moffitt T.E. Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat. Rev. Neurosci. 2006, 7(7):583-590.
    • (2006) Nat. Rev. Neurosci. , vol.7 , Issue.7 , pp. 583-590
    • Caspi, A.1    Moffitt, T.E.2
  • 10
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: a convergence point for many signalling pathways
    • Chao M.V. Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci. 2003, 4(4):299-309.
    • (2003) Nat. Rev. Neurosci. , vol.4 , Issue.4 , pp. 299-309
    • Chao, M.V.1
  • 11
    • 84862240430 scopus 로고    scopus 로고
    • Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development
    • Chen Y., Fu W.-Y., Ip J.P.K., Ye T., Fu A.K.Y., Chao M.V., Ip N.Y. Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development. J. Neurosci. Off. J. Soc. Neurosci. 2012, 32(24):8263-8269.
    • (2012) J. Neurosci. Off. J. Soc. Neurosci. , vol.32 , Issue.24 , pp. 8263-8269
    • Chen, Y.1    Fu, W.-Y.2    Ip, J.P.K.3    Ye, T.4    Fu, A.K.Y.5    Chao, M.V.6    Ip, N.Y.7
  • 12
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics C. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 2013, 381(9875):1371-1379.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
  • 15
    • 84855942636 scopus 로고    scopus 로고
    • Recent genomic advances in schizophrenia
    • Doherty J.L., O'Donovan M.C., Owen M.J. Recent genomic advances in schizophrenia. Clin. Genet. 2012, 81(2):103-109.
    • (2012) Clin. Genet. , vol.81 , Issue.2 , pp. 103-109
    • Doherty, J.L.1    O'Donovan, M.C.2    Owen, M.J.3
  • 19
    • 33947642632 scopus 로고    scopus 로고
    • Stress during development: impact on neuroplasticity and relevance to psychopathology
    • Fumagalli F., Molteni R., Racagni G., Riva M.A. Stress during development: impact on neuroplasticity and relevance to psychopathology. Prog. Neurobiol. 2007, 81(4):197-217.
    • (2007) Prog. Neurobiol. , vol.81 , Issue.4 , pp. 197-217
    • Fumagalli, F.1    Molteni, R.2    Racagni, G.3    Riva, M.A.4
  • 22
    • 2342548182 scopus 로고    scopus 로고
    • P75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity
    • Gehler S., Gallo G., Veien E., Letourneau P.C. p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity. J. Neurosci. 2004, 24(18):4363-4372.
    • (2004) J. Neurosci. , vol.24 , Issue.18 , pp. 4363-4372
    • Gehler, S.1    Gallo, G.2    Veien, E.3    Letourneau, P.C.4
  • 23
    • 84884288041 scopus 로고    scopus 로고
    • Dendritic spine pathology in schizophrenia
    • Glausier J.R., Lewis D.A. Dendritic spine pathology in schizophrenia. Neuroscience 2013, 251:90-107.
    • (2013) Neuroscience , vol.251 , pp. 90-107
    • Glausier, J.R.1    Lewis, D.A.2
  • 24
    • 46149128942 scopus 로고
    • Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease
    • Goedert M., Fine A., Hunt S.P., Ullrich A. Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease. Brain Res. 1986, 387(1):85-92.
    • (1986) Brain Res. , vol.387 , Issue.1 , pp. 85-92
    • Goedert, M.1    Fine, A.2    Hunt, S.P.3    Ullrich, A.4
  • 25
    • 0022549757 scopus 로고
    • Nerve growth factor and Alzheimer's disease
    • Hefti F., Weiner W.J. Nerve growth factor and Alzheimer's disease. Ann. Neurol. 1986, 20(3):275-281.
    • (1986) Ann. Neurol. , vol.20 , Issue.3 , pp. 275-281
    • Hefti, F.1    Weiner, W.J.2
  • 26
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: roles in neuronal signal transduction
    • Huang E.J., Reichardt L.F. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 2003, 72:609-642.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 27
  • 28
    • 77954958928 scopus 로고    scopus 로고
    • An inverse relationship between cortisol and BDNF levels in schizophrenia: data from human postmortem and animal studies
    • Issa G., Wilson C., Terry A.V., Pillai A. An inverse relationship between cortisol and BDNF levels in schizophrenia: data from human postmortem and animal studies. Neurobiol. Dis. 2010, 39(3):327-333.
    • (2010) Neurobiol. Dis. , vol.39 , Issue.3 , pp. 327-333
    • Issa, G.1    Wilson, C.2    Terry, A.V.3    Pillai, A.4
  • 29
  • 30
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13(2):261-276.
    • (1987) Schizophr. Bull. , vol.13 , Issue.2 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 31
    • 0344196904 scopus 로고    scopus 로고
    • SAM domains: uniform structure, diversity of function
    • Kim C.A., Bowie J.U. SAM domains: uniform structure, diversity of function. Trends Biochem. Sci. 2003, 28(12):625-628.
    • (2003) Trends Biochem. Sci. , vol.28 , Issue.12 , pp. 625-628
    • Kim, C.A.1    Bowie, J.U.2
  • 32
    • 79952315874 scopus 로고    scopus 로고
    • Is schizophrenia on the autism spectrum?
    • King B.H., Lord C. Is schizophrenia on the autism spectrum?. Brain Res. 2011, 1380:34-41.
    • (2011) Brain Res. , vol.1380 , pp. 34-41
    • King, B.H.1    Lord, C.2
  • 33
    • 0035141510 scopus 로고    scopus 로고
    • An evolutionarily conserved transmembrane protein that is a novel downstream target of neurotrophin and ephrin receptors
    • Kong H., Boulter J., Weber J.L., Lai C., Chao M.V. An evolutionarily conserved transmembrane protein that is a novel downstream target of neurotrophin and ephrin receptors. J. Neurosci. Off. J. Soc. Neurosci. 2001, 21(1):176-185.
    • (2001) J. Neurosci. Off. J. Soc. Neurosci. , vol.21 , Issue.1 , pp. 176-185
    • Kong, H.1    Boulter, J.2    Weber, J.L.3    Lai, C.4    Chao, M.V.5
  • 34
    • 84915752827 scopus 로고    scopus 로고
    • Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder
    • Konopaske G.T., Lange N., Coyle J.T., Benes F.M. Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder. JAMA Psychiatry 2014, 71(12):1323-1331.
    • (2014) JAMA Psychiatry , vol.71 , Issue.12 , pp. 1323-1331
    • Konopaske, G.T.1    Lange, N.2    Coyle, J.T.3    Benes, F.M.4
  • 35
    • 84884242662 scopus 로고    scopus 로고
    • The interaction of BDNF and NTRK2 gene increases the susceptibility of paranoid schizophrenia
    • Lin Z., Su Y., Zhang C., Xing M., Ding W., Liao L., Guan Y., Li Z., Cui D. The interaction of BDNF and NTRK2 gene increases the susceptibility of paranoid schizophrenia. PLoS One 2013, 8(9):e74264.
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e74264
    • Lin, Z.1    Su, Y.2    Zhang, C.3    Xing, M.4    Ding, W.5    Liao, L.6    Guan, Y.7    Li, Z.8    Cui, D.9
  • 38
    • 84920741938 scopus 로고    scopus 로고
    • Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function
    • Mariga A., Zavadil J., Ginsberg S.D., Chao M.V. Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function. Dev. Neurobiol. 2015, 75(2):173-192.
    • (2015) Dev. Neurobiol. , vol.75 , Issue.2 , pp. 173-192
    • Mariga, A.1    Zavadil, J.2    Ginsberg, S.D.3    Chao, M.V.4
  • 40
    • 0003679737 scopus 로고
    • Clinical Neurogenetic Branch, Intramural Research Program, NIMH
    • Maxwell M. Family Interview for Genetic Studies 1992, Clinical Neurogenetic Branch, Intramural Research Program, NIMH.
    • (1992) Family Interview for Genetic Studies
    • Maxwell, M.1
  • 41
    • 0038779583 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia: a review of recent developments
    • McGrath J.J., Féron F.P., Burne T.H.J., Mackay-Sim A., Eyles D.W. The neurodevelopmental hypothesis of schizophrenia: a review of recent developments. Ann. Med. 2003, 35(2):86-93.
    • (2003) Ann. Med. , vol.35 , Issue.2 , pp. 86-93
    • McGrath, J.J.1    Féron, F.P.2    Burne, T.H.J.3    Mackay-Sim, A.4    Eyles, D.W.5
  • 42
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988, 16(3):1215.
    • (1988) Nucleic Acids Res. , vol.16 , Issue.3 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 44
    • 0029809187 scopus 로고    scopus 로고
    • N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway
    • Nakamura T., Sanokawa R., Sasaki Y., Ayusawa D., Oishi M., Mori N. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway. Oncogene 1996, 13(6):1111-1121.
    • (1996) Oncogene , vol.13 , Issue.6 , pp. 1111-1121
    • Nakamura, T.1    Sanokawa, R.2    Sasaki, Y.3    Ayusawa, D.4    Oishi, M.5    Mori, N.6
  • 45
    • 77953554495 scopus 로고    scopus 로고
    • Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio
    • Neubrand V.E., Thomas C., Schmidt S., Debant A., Schiavo G. Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio. J. Cell Sci. 2010, 123(12):2111-2123.
    • (2010) J. Cell Sci. , vol.123 , Issue.12 , pp. 2111-2123
    • Neubrand, V.E.1    Thomas, C.2    Schmidt, S.3    Debant, A.4    Schiavo, G.5
  • 46
    • 84863114867 scopus 로고    scopus 로고
    • Kidins220/ARMS as a functional mediator of multiple receptor signalling pathways
    • Neubrand V.E., Cesca F., Benfenati F., Schiavo G. Kidins220/ARMS as a functional mediator of multiple receptor signalling pathways. J. Cell Sci. 2012, 125(8):1845-1854.
    • (2012) J. Cell Sci. , vol.125 , Issue.8 , pp. 1845-1854
    • Neubrand, V.E.1    Cesca, F.2    Benfenati, F.3    Schiavo, G.4
  • 48
    • 77955936385 scopus 로고    scopus 로고
    • BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration
    • Ortega J.A., Alcantara S. BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration. Cereb. Cortex 2010, 20(9):2132-2144.
    • (2010) Cereb. Cortex , vol.20 , Issue.9 , pp. 2132-2144
    • Ortega, J.A.1    Alcantara, S.2
  • 49
    • 84871408179 scopus 로고    scopus 로고
    • Neurotrophin regulation of neural circuit development and function
    • Park H., Poo M.M. Neurotrophin regulation of neural circuit development and function. Nat. Rev. Neurosci. 2013, 14(1):7-23.
    • (2013) Nat. Rev. Neurosci. , vol.14 , Issue.1 , pp. 7-23
    • Park, H.1    Poo, M.M.2
  • 52
    • 84901235787 scopus 로고    scopus 로고
    • Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders
    • Ray M.T., Shannon Weickert C., Webster M.J. Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders. Transcult. Psychiatry 2014, 4:e389.
    • (2014) Transcult. Psychiatry , vol.4 , pp. e389
    • Ray, M.T.1    Shannon Weickert, C.2    Webster, M.J.3
  • 53
    • 0031022602 scopus 로고    scopus 로고
    • SAM as a protein interaction domain involved in developmental regulation
    • Schultz J., Bork P., Ponting C.P., Hofmann K. SAM as a protein interaction domain involved in developmental regulation. Protein Sci. 1997, 6(1):249-253.
    • (1997) Protein Sci. , vol.6 , Issue.1 , pp. 249-253
    • Schultz, J.1    Bork, P.2    Ponting, C.P.3    Hofmann, K.4
  • 58
    • 0142219372 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response
    • Tsai S.J., Cheng C.Y., Yu Y.W., Chen T.J., Hong C.J. Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2003, 123B(1):19-22.
    • (2003) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.123B , Issue.1 , pp. 19-22
    • Tsai, S.J.1    Cheng, C.Y.2    Yu, Y.W.3    Chen, T.J.4    Hong, C.J.5
  • 63
    • 0030783811 scopus 로고    scopus 로고
    • Empirical assessment of the factorial structure of clinical symptoms in schizophrenia. A multisite, multimodel evaluation of the factorial structure of the Positive and Negative Syndrome Scale. The PANSS Study Group
    • White L., Harvey P.D., Opler L., Lindenmayer J.P. Empirical assessment of the factorial structure of clinical symptoms in schizophrenia. A multisite, multimodel evaluation of the factorial structure of the Positive and Negative Syndrome Scale. The PANSS Study Group. Psychopathology 1997, 30(5):263-274.
    • (1997) Psychopathology , vol.30 , Issue.5 , pp. 263-274
    • White, L.1    Harvey, P.D.2    Opler, L.3    Lindenmayer, J.P.4
  • 64
    • 67749129484 scopus 로고    scopus 로고
    • Ankyrin repeat-rich membrane spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo
    • Wu S.H., Arevalo J.C., Sarti F., Tessarollo L., Gan W.-B., Chao M.V. Ankyrin repeat-rich membrane spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Dev. Neurobiol. 2009, 69(9):547-557.
    • (2009) Dev. Neurobiol. , vol.69 , Issue.9 , pp. 547-557
    • Wu, S.H.1    Arevalo, J.C.2    Sarti, F.3    Tessarollo, L.4    Gan, W.-B.5    Chao, M.V.6
  • 66
    • 33747172771 scopus 로고    scopus 로고
    • Mechanisms of neurotrophin receptor signalling
    • Zampieri N., Chao M.V. Mechanisms of neurotrophin receptor signalling. Biochem. Soc. Trans. 2006, 34(Pt 4):607-611.
    • (2006) Biochem. Soc. Trans. , vol.34 , Issue.Pt 4 , pp. 607-611
    • Zampieri, N.1    Chao, M.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.