Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a potent activator of granulosa cells and improves oocyte quality

Journal of Biological Chemistry

Volumn 290, Issue 39, 2015, Pages 24007-24020

  Mottershead, David G ^a,c   Sugimura, Satoshi ^a,d   Al Musawi, Sara L ^e   Li, Jing Jie ^a,f   Richani, Dulama ^a   White, Melissa A ^a   Martin, Georgia A ^a   Trotta, Andrew P ^a   Ritter, Lesley J ^a,b   Shi, Junyan ^a   Mueller, Thomas D ^g   Harrison, Craig A ^e   Gilchrist, Robert B ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c Mottasis Oy Ltd   (Finland)

^d TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^e HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f SUN YAT SEN UNIVERSITY   (China)

^g UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BONE; CELL PROLIFERATION; CHEMICAL ACTIVATION; MAMMALS;

BONE MORPHOGENETIC PROTEINS; EMBRYO DEVELOPMENT; GROWTH DIFFERENTIATION; HETERODIMERIC COMPLEXES; PHYSICAL INTERACTIONS; SIGNALING PATHWAYS; STRUCTURAL MODELING; TRANSFORMING GROWTH FACTOR BETA;

BIOACTIVITY;

BONE MORPHOGENETIC PROTEIN 15; CUMULIN; GROWTH DIFFERENTIATION FACTOR 9; HETERODIMER; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; BMP15 PROTEIN, HUMAN; BMP15 PROTEIN, MOUSE; GDF9 PROTEIN, HUMAN; GDF9 PROTEIN, MOUSE; SMAD PROTEIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; CUMULUS CELL; DIMERIZATION; GENE EXPRESSION; GRANULOSA CELL; MOLECULAR MODEL; MOUSE; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; ANIMAL; CYTOLOGY; FEMALE; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 15; FEMALE; GRANULOSA CELLS; GROWTH DIFFERENTIATION FACTOR 9; HUMANS; MICE; OOCYTES; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SMAD PROTEINS;

EID: 84942333248     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.671487     Document Type: Article

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