Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9: BMP15 heterodimer activities

Biology of Reproduction

Volumn 91, Issue 6, 2014, Pages

  Peng, Jia ^a   Wigglesworth, Karen ^b   Rangarajan, Adithya ^a   Eppig, John J ^b   Thompson, Thomas B ^c   Matzuk, Martin M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b JACKSON LABORATORY   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Follicular development; Growth factors; Ovary

Indexed keywords

AMINO ACID; ARGININE; BONE MORPHOGENETIC PROTEIN 15; GROWTH DIFFERENTIATION FACTOR 9; HETERODIMER; HOMODIMER; LIGAND; BMP15 PROTEIN, HUMAN; BMP15 PROTEIN, MOUSE; GDF9 PROTEIN, HUMAN; GDF9 PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CELL CLONE; CUMULUS CELL; FEMALE; GENETIC TRANSFECTION; GRANULOSA CELL; HEK293 CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; GENETICS; METABOLISM; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE;

MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; BONE MORPHOGENETIC PROTEIN 15; CELLS, CULTURED; FEMALE; GROWTH DIFFERENTIATION FACTOR 9; HEK293 CELLS; HUMANS; MICE; MICE, INBRED C57BL; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84930400121     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.114.123158     Document Type: Article

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