LGR5 promotes breast cancer progression and maintains stem-like cells through activation of wnt/β-catenin signaling

Stem Cells

Volumn 33, Issue 10, 2015, Pages 2913-2924

  Yang, Lu ^a   Xie, Xiaoming ^a   Tang, Hailin ^a   Kong, Yanan ^a   Xie, Xinhua ^a   Chen, Jianping ^b   Song, Cailu ^a   Liu, Xiaoping ^a   Ye, Feng ^a   Li, Ning ^a   Wang, Neng ^b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Breast cancer; Cancer stem cell; EMT; LGR5; Wnt Catenin

Indexed keywords

BETA CATENIN; FIBRONECTIN; G PROTEIN COUPLED RECEPTOR; PROTEIN LGR5; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WNT PROTEIN; LGR5 PROTEIN, HUMAN;

ADULT; ADULT STEM CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CANCER STEM CELL; CARCINOGENICITY; CELL MIGRATION; CELL MOTILITY; CELL RENEWAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DISTANT METASTASIS; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG METASTASIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NONHUMAN; OVERALL SURVIVAL; PROTEIN EXPRESSION; TUMOR SPHEROID; WESTERN BLOTTING; WNT SIGNALING PATHWAY; AGED; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MOUSE; MULTICELLULAR SPHEROID; PATHOLOGY;

ADULT; AGED; ANIMALS; BETA CATENIN; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MIDDLE AGED; NEOPLASTIC STEM CELLS; RECEPTORS, G-PROTEIN-COUPLED; SPHEROIDS, CELLULAR; WNT SIGNALING PATHWAY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84942305390     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2083     Document Type: Article

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