Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures

Nature Communications

Volumn 5, Issue , 2014, Pages

  Tomioka, Naoko H ^a,i   Yasuda, Hiroki ^b   Miyamoto, Hiroyuki ^a,c   Hatayama, Minoru ^a,d   Morimura, Naoko ^a   Matsumoto, Yoshifumi ^a   Suzuki, Toshimitsu ^a   Odagawa, Maya ^a   Odaka, Yuri S ^a   Iwayama, Yoshimi ^a   Won Um, Ji ^e   Ko, Jaewon ^e   Inoue, Yushi ^f   Kaneko, Sunao ^g   Hirose, Shinichi ^h   Yamada, Kazuyuki ^a   Yoshikawa, Takeo ^a   Yamakawa, Kazuhiro ^a   Aruga, Jun ^a,d  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^e Yonsei University   (South Korea)

^f SHIZUOKA INSTITUTE OF EPILEPSY AND NEUROLOGICAL DISORDERS   (Japan)

^g HIROSAKI UNIVERSITY   (Japan)

^h FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ELFN1 PROTEIN; MGLUR7 PROTEIN; PROTEIN; SOMATOSTATIN; UNCLASSIFIED DRUG; EXTRACELLULAR LEUCINE-RICH REPEAT FIBRONECTIN CONTAINING 1 PROTEIN, HUMAN; EXTRACELLULAR LEUCINE-RICH REPEAT FIBRONECTIN CONTAINING 1 PROTEIN, MOUSE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 7; NERVE PROTEIN;

BRAIN; GENE EXPRESSION; HORMONE; INHIBITOR; MENTAL HEALTH; MUTATION; NEUROLOGY; PROTEIN; RODENT;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; CARBOXY TERMINAL SEQUENCE; CHILD; CONTROLLED STUDY; DENTATE GYRUS; DENTATE HILUS; EPILEPSY; FEMALE; HIPPOCAMPAL CA1 REGION; HUMAN; HUMAN CELL; INTERNEURON; MALE; MISSENSE MUTATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; POSTNATAL DEVELOPMENT; PROTEIN INTERACTION; SEIZURE; SYNAPSE; AGED; AMINO ACID SEQUENCE; ANIMAL; AUTISM; C57BL MOUSE; CASE CONTROL STUDY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE; VERY ELDERLY; YOUNG ADULT;

MUS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AUTISTIC DISORDER; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; HUMANS; INTERNEURONS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SEIZURES; YOUNG ADULT;

EID: 84942179515     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5501     Document Type: Article

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