A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B

Cancer Science

Volumn 106, Issue 9, 2015, Pages 1174-1181

  Suzuki, Hiroshi I ^a,b   Katsura, Akihiro ^b   Miyazono, Kohei ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Biogenesis; Dis3l2; Let 7; Lin28B; MCPIP1

Indexed keywords

LIN28A PROTEIN; LIN28B PROTEIN; MICRORNA; RIBONUCLEASE; RNA BINDING PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; DIS3L2 PROTEIN, HUMAN; DNA BINDING PROTEIN; EXORIBONUCLEASE; LIN28B PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN; TRANSCRIPTION FACTOR; ZC3H12A PROTEIN, HUMAN; ZCCHC11 PROTEIN, HUMAN;

ARTICLE; BIOGENESIS; CANCER CELL; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; GENE SILENCING; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MOLECULAR BIOLOGY; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; URIDYLATION; CELL LINE; CELL NUCLEUS; HEK293 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; METABOLISM; TUMOR CELL LINE;

CELL LINE; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; DNA-BINDING PROTEINS; EXORIBONUCLEASES; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; MICRORNAS; RIBONUCLEASES; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 84942162990     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12721     Document Type: Article

References (48)

1. Suzuki HI, Miyazono K. Emerging complexity of microRNA generation cascades. J Biochem 2011; 149: 15-25.
2. Suzuki HI, Miyazono K. Dynamics of microRNA biogenesis: crosstalk between p53 network and microRNA processing pathway. J Mol Med (Berl) 2010; 88: 1085-94.
3. Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008; 14: 1539-49.
4. Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science 2008; 320: 97-100.
5. Rybak A, Fuchs H, Smirnova L et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008; 10: 987-93.
6. Heo I, Joo C, Cho J, Ha M, Han J, Kim VN. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008; 32: 276-84.
7. Ouchi Y, Yamamoto J, Iwamoto T. The heterochronic genes lin-28a and lin-28b play an essential and evolutionarily conserved role in early zebrafish development. PLoS One 2014; 9: e88086.
8. Guo Y, Chen Y, Ito H et al. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006; 384: 51-61.
9. Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-20.
10. Ma X, Li C, Sun L et al. Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1. Nat Commun 2014; 5: 5212.
11. Liu Y, Li H, Feng J et al. Lin28 induces epithelial-to-mesenchymal transition and stemness via downregulation of let-7a in breast cancer cells. PLoS One 2013; 8: e83083.
12. Yang X, Lin X, Zhong X et al. Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer Res 2010; 70: 9463-72.
13. Heo I, Joo C, Kim Y et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009; 138: 696-708.
14. Lehrbach NJ, Armisen J, Lightfoot HL et al. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol 2009; 16: 1016-20.
15. Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009; 16: 1021-5.
16. Thornton JE, Chang HM, Piskounova E, Gregory RI. Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). RNA 2012; 18: 1875-85.
17. Chang HM, Triboulet R, Thornton JE, Gregory RI. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature 2013; 497: 244-8.
18. Ustianenko D, Hrossova D, Potesil D et al. Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs. RNA 2013; 19: 1632-8.
19. Van Wynsberghe PM, Kai ZS, Massirer KB, Burton VH, Yeo GW, Pasquinelli AE. LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans. Nat Struct Mol Biol 2011; 18: 302-8.
20. Piskounova E, Polytarchou C, Thornton JE et al. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell 2011; 147: 1066-79.
21. Hafner M, Max KE, Bandaru P et al. Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition. RNA 2013; 19: 613-26.
22. Suzuki HI, Arase M, Matsuyama H et al. MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 2011; 44: 424-36.
23. Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, Miyazono K. Modulation of microRNA processing by p53. Nature 2009; 460: 529-33.
24. Matsuyama H, Suzuki HI, Nishimori H et al. miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma. Blood 2011; 118: 6881-92.
25. Suzuki HI, Matsuyama H, Noguchi M et al. Computational dissection of distinct microRNA activity signatures associated with peripheral T cell lymphoma subtypes. Leukemia 2013; 27: 2107-11.
26. Barretina J, Caponigro G, Stransky N et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012; 483: 603-7.
27. Subramanian A, Tamayo P, Mootha VK et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005; 102: 15545-50.
28. Gurtan AM, Ravi A, Rahl PB et al. Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts. Genes Dev 2013; 27: 941-54.
29. Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997; 88: 637-46.
30. Yang DH, Moss EG. Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene Expr Patterns 2003; 3: 719-26.
31. Astuti D, Morris MR, Cooper WN et al. Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. Nat Genet 2012; 44: 277-84.
32. Malecki M, Viegas SC, Carneiro T et al. The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway. EMBO J 2013; 32: 1842-54.
33. Viswanathan SR, Powers JT, Einhorn W et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 2009; 41: 843-8.
34. West JA, Viswanathan SR, Yabuuchi A et al. A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature 2009; 460: 909-13.
35. King CE, Cuatrecasas M, Castells A, Sepulveda AR, Lee JS, Rustgi AK. LIN28B promotes colon cancer progression and metastasis. Cancer Res 2011; 71: 4260-8.
36. Suzuki HI, Miyazono K. Control of microRNA maturation by p53 tumor suppressor and MCPIP1 ribonuclease. Enzymes 2012; 32: 163-83.
37. Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009; 139: 693-706.
38. Matsushita K, Takeuchi O, Standley DM et al. Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature 2009; 458: 1185-90.
39. Jura J, Skalniak L, Koj A. Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions. Biochim Biophys Acta 2012; 1823: 1905-13.
40. Thornton JE, Gregory RI. How does Lin28 let-7 control development and disease? Trends Cell Biol 2012; 22: 474-82.
41. Urbach A, Yermalovich A, Zhang J et al. Lin28 sustains early renal progenitors and induces Wilms tumor. Genes Dev 2014; 28: 971-82.
42. Molenaar JJ, Domingo-Fernandez R, Ebus ME et al. LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. Nat Genet 2012; 44: 1199-206.
43. Diskin SJ, Capasso M, Schnepp RW et al. Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. Nat Genet 2012; 44: 1126-30.
44. Charafe-Jauffret E, Ginestier C, Monville F et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 2006; 25: 2273-84.
45. Pujana MA, Han JD, Starita LM et al. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet 2007; 39: 1338-49.
46. Chang TC, Zeitels LR, Hwang HW et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A 2009; 106: 3384-9.
47. Kim SK, Lee H, Han K et al. SET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCs. Cell Stem Cell 2014; 15: 735-49.
48. Balzer E, Moss EG. Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules. RNA Biol 2007; 4: 16-25.