-
1
-
-
77349091545
-
Biological and clinical significance of KRAS mutations in lung cancer: An oncogenic driver that contrasts with EGFR mutation
-
Suda, K., Tomizawa, K. & Mitsudomi, T. Biological and clinical significance of KRAS mutations in lung cancer: An oncogenic driver that contrasts with EGFR mutation. Cancer Metast. Rev. 29, 49-60 (2010).
-
(2010)
Cancer Metast. Rev
, vol.29
, pp. 49-60
-
-
Suda, K.1
Tomizawa, K.2
Mitsudomi, T.3
-
2
-
-
84920797312
-
Successes and limitations of targeted cancer therapy in lung cancer
-
Suda, K. & Mitsudomi, T. Successes and limitations of targeted cancer therapy in lung cancer. Progress in Tumor Research 41, 62-77 (2014).
-
(2014)
Progress in Tumor Research
, vol.41
, pp. 62-77
-
-
Suda, K.1
Mitsudomi, T.2
-
3
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
Sequist, L. V. et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci. Transl. Med. 3, 75ra26 (2011).
-
(2011)
Sci. Transl. Med
, vol.3
, pp. 75ra26
-
-
Sequist, L.V.1
-
4
-
-
84867991219
-
Acquired resistance mechanisms to tyrosine kinase inhibitors in lung cancer with activating epidermal growth factor receptor mutation-diversity, ductility, and destiny
-
Suda, K., Mizuuchi, H., Maehara, Y. & Mitsudomi, T. Acquired resistance mechanisms to tyrosine kinase inhibitors in lung cancer with activating epidermal growth factor receptor mutation-diversity, ductility, and destiny. Cancer Metast. Rev. 31, 807-14 (2012).
-
(2012)
Cancer Metast. Rev
, vol.31
, pp. 807-814
-
-
Suda, K.1
Mizuuchi, H.2
Maehara, Y.3
Mitsudomi, T.4
-
5
-
-
84928746232
-
Rociletinib in EGFR-mutated non-small-cell lung cancer
-
Sequist, L. V. et al. Rociletinib in EGFR-mutated non-small-cell lung cancer. N. Engl. J. Med. 372, 1700-9 (2015).
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 1700-1709
-
-
Sequist, L.V.1
-
6
-
-
33745913034
-
EGFR mutations in small-cell lung cancers in patients who have never smoked
-
Zakowski, M. F., Ladanyi, M. & Kris, M. G. EGFR mutations in small-cell lung cancers in patients who have never smoked. N. Eng. J. Med. 355, 213-5 (2006).
-
(2006)
N. Eng. J. Med
, vol.355
, pp. 213-215
-
-
Zakowski, M.F.1
Ladanyi, M.2
Kris, M.G.3
-
7
-
-
35748973894
-
Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation
-
Morinaga, R. et al. Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation. Lung Cancer 58, 411-3 (2007).
-
(2007)
Lung Cancer
, vol.58
, pp. 411-413
-
-
Morinaga, R.1
-
8
-
-
58149149814
-
Epidermal growth factor receptor mutations in small cell lung cancer
-
Tatematsu, A. et al. Epidermal growth factor receptor mutations in small cell lung cancer. Clin. Cancer Res. 14, 6092-6 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 6092-6096
-
-
Tatematsu, A.1
-
9
-
-
84861306096
-
Secondary resistance to erlotinib: Acquired T790M mutation and small-cell lung cancer transformation in the same patient
-
Fallet, V. et al. Secondary resistance to erlotinib: Acquired T790M mutation and small-cell lung cancer transformation in the same patient. J. Thorac. Oncol. 7, 1061-3 (2012).
-
(2012)
J. Thorac. Oncol
, vol.7
, pp. 1061-1063
-
-
Fallet, V.1
-
10
-
-
84887020905
-
Transformation to small-cell lung cancer following treatment with EGFR tyrosine kinase inhibitors in a patient with lung adenocarcinoma
-
Watanabe, S. et al. Transformation to small-cell lung cancer following treatment with EGFR tyrosine kinase inhibitors in a patient with lung adenocarcinoma. Lung Cancer 82, 370-2 (2013).
-
(2013)
Lung Cancer
, vol.82
, pp. 370-372
-
-
Watanabe, S.1
-
11
-
-
84877100240
-
Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFRmutant lung cancers
-
Yu, H. A. et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFRmutant lung cancers. Clin. Cancer Res. 19, 2240-7 (2013).
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 2240-2247
-
-
Yu, H.A.1
-
12
-
-
84875264732
-
High grade" neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFRmutant lung adenocarcinoma
-
Popat, S. et al. Transformation to "high grade" neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFRmutant lung adenocarcinoma. Lung Cancer 80, 1-4 (2013).
-
(2013)
Lung Cancer
, vol.80
, pp. 1-4
-
-
Popat, S.1
-
13
-
-
84901602817
-
Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients
-
Kuiper, J. L. et al. Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients. Lung Cancer 85, 19-24 (2014).
-
(2014)
Lung Cancer
, vol.85
, pp. 19-24
-
-
Kuiper, J.L.1
-
14
-
-
84901474861
-
Small-cell lung cancers in patients who never smoked cigarettes
-
Varghese, A. M. et al. Small-cell lung cancers in patients who never smoked cigarettes. J. Thorac. Oncol. 9, 892-6 (2014).
-
(2014)
J. Thorac. Oncol
, vol.9
, pp. 892-896
-
-
Varghese, A.M.1
-
15
-
-
84924590266
-
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
-
Niederst, M. J. et al. RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. Nat. Commun. 6, 6377 (2015).
-
(2015)
Nat. Commun
, vol.6
, pp. 6377
-
-
Niederst, M.J.1
-
16
-
-
74949110711
-
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Jackman, D. et al. Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. J. Clin. Oncol. 28, 357-60 (2010).
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 357-360
-
-
Jackman, D.1
-
17
-
-
84942091907
-
-
ed. Ke Xu Nova Science Publishers
-
Suda, K. & Mitsudomi, T. Syntax of referencing in PTEN structure, mechanisms-of-Action, role in cell signaling and regulation (ed. Ke Xu.) 101-18 (Nova Science Publishers, 2013).
-
(2013)
Syntax of Referencing in PTEN Structure, Mechanisms-of-Action, Role in Cell Signaling and Regulation
, vol.101
, pp. 18
-
-
Suda, K.1
Mitsudomi, T.2
-
18
-
-
0031596872
-
Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers
-
Kohno, T., Takahashi, M., Manda, R. & Yokota, J. Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers. Genes Chromosomes Cancer 22, 152-6 (1998).
-
(1998)
Genes Chromosomes Cancer
, vol.22
, pp. 152-156
-
-
Kohno, T.1
Takahashi, M.2
Manda, R.3
Yokota, J.4
-
19
-
-
0032581519
-
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers
-
Yokomizo, A. et al. PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers. Oncogene 17, 475-9 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 475-479
-
-
Yokomizo, A.1
-
20
-
-
7844247587
-
Mutation analysis of the PTEN/MMAC1 gene in lung cancer
-
Forgacs, E. et al. Mutation analysis of the PTEN/MMAC1 gene in lung cancer. Oncogene 17, 1557-65 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 1557-1565
-
-
Forgacs, E.1
-
21
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels, Y. et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 304, 554 (2004).
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
-
22
-
-
78349265779
-
Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer
-
98
-
Suda, K. et al. Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer. Clin. Cancer Res. 16, 5489-98 (2010).
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 5489
-
-
Suda, K.1
-
23
-
-
84885146751
-
EGFR-mutated lung cancer with T790M-Acquired resistance in the brain and histologic transformation in the lung
-
Scher, K. S., Saldivar, J. S., Fishbein, M., Marchevsky, A. & Reckamp, K. L. EGFR-mutated lung cancer with T790M-Acquired resistance in the brain and histologic transformation in the lung. J. Natl. Compr. Canc. Netw. 11, 1040-4 (2013).
-
(2013)
J. Natl. Compr. Canc. Netw
, vol.11
, pp. 1040-1044
-
-
Scher, K.S.1
Saldivar, J.S.2
Fishbein, M.3
Marchevsky, A.4
Reckamp, K.L.5
-
24
-
-
84937414146
-
Heterogeneity underlies the emergence of EGFR t790 wild-Type clones following treatment of t790mpositive cancers with a third generation EGFR inhibitor
-
in press
-
Piotrowska, Z. et al. Heterogeneity Underlies the Emergence of EGFR T790 Wild-Type Clones Following Treatment of T790MPositive Cancers with a Third Generation EGFR Inhibitor. Cancer Discov. in press (2015).
-
(2015)
Cancer Discov
-
-
Piotrowska, Z.1
-
25
-
-
57149089886
-
EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
-
Takano, T. et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan. J. Clin. Oncol. 26, 5589-95 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 5589-5595
-
-
Takano, T.1
-
26
-
-
84904110115
-
CRKL amplification is rare as a mechanism for acquired resistance to kinase inhibitors in lung cancers with epidermal growth factor receptor mutation
-
Suda, K. et al. CRKL amplification is rare as a mechanism for acquired resistance to kinase inhibitors in lung cancers with epidermal growth factor receptor mutation. Lung Cancer 85, 147-51 (2014).
-
(2014)
Lung Cancer
, vol.85
, pp. 147-151
-
-
Suda, K.1
-
27
-
-
84923097689
-
Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions
-
Sakai, K. et al. Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions. Oncotarget 5, 9641-9 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 9641-9649
-
-
Sakai, K.1
|