Transformation to " high grade" neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFR-mutant lung adenocarcinoma

Lung Cancer

Volumn 80, Issue 1, 2013, Pages 1-4

  Popat, S ^a,b   Wotherspoon, A ^a   Nutting, C M ^a   Gonzalez, D ^a   Nicholson, A G ^b,c   O'Brien, M ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Adenocarcinoma; EGFR; Mutation; Neuroendocrine; NSCLC; SCLC

Indexed keywords

AFATINIB; CARBOPLATIN; CD56 ANTIGEN; CHROMOGRANIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOKERATIN 7; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; ETOPOSIDE; NAVELBINE; PEMETREXED; PROTEIN TYROSINE KINASE INHIBITOR;

ADULT; BRAIN METASTASIS; CANCER CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CAPILLARY ELECTROPHORESIS; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; DYSPHAGIA; EXON; FEMALE; GENE DELETION; GENOTYPE; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER METASTASIS; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; METASTASIS RESECTION; MULTIPLE CYCLE TREATMENT; NEUROENDOCRINE TUMOR; PRIORITY JOURNAL; RADIATION DOSE; REVIEW; SINGLE STRAND CONFORMATION POLYMORPHISM; THORACOTOMY; TONIC CLONIC SEIZURE;

ADENOCARCINOMA; CARCINOMA, NEUROENDOCRINE; CELL TRANSFORMATION, NEOPLASTIC; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MIDDLE AGED; MUTATION; NEOPLASM GRADING; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMALL CELL LUNG CARCINOMA;

EID: 84875264732     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2012.12.019     Document Type: Review

References (4)

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