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Volumn 61, Issue 7, 2015, Pages 1169-1178

Establishment and Replenishment of the Viral Reservoir in Perinatally HIV-1-infected Children Initiating Very Early Antiretroviral Therapy

Author keywords

early antiretroviral therapy; HIV 1; vertical infection; viral reservoir

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; LAMIVUDINE PLUS NEVIRAPINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; NEVIRAPINE; VIRUS DNA; ANTIRETROVIRUS AGENT;

EID: 84942134668     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/civ456     Document Type: Article
Times cited : (98)

References (40)
  • 1
    • 34347400223 scopus 로고    scopus 로고
    • International perspectives, progress, and future challenges of paediatric HIV infection
    • Prendergast A, Tudor-Williams G, Jeena P, Burchett S, Goulder P. International perspectives, progress, and future challenges of paediatric HIV infection. Lancet 2007; 370:68-80
    • (2007) Lancet , vol.370 , pp. 68-80
    • Prendergast, A.1    Tudor-Williams, G.2    Jeena, P.3    Burchett, S.4    Goulder, P.5
  • 2
    • 0030962564 scopus 로고    scopus 로고
    • The relationship between serum human immunodeficiency virus type 1 (HIV-1) RNA level, CD4 lymphocyte percent, and long-term mortality risk in HIV-1-infected children. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group
    • Mofenson LM, Korelitz J, MeyerWA III, et al. The relationship between serum human immunodeficiency virus type 1 (HIV-1) RNA level, CD4 lymphocyte percent, and long-term mortality risk in HIV-1-infected children. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group. J Infect Dis 1997; 175:1029-38
    • (1997) J Infect Dis , vol.175 , pp. 1029-1038
    • Mofenson, L.M.1    Korelitz, J.2    Meyer, W.A.3
  • 3
    • 0030457164 scopus 로고    scopus 로고
    • Age-and time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virus
    • McIntosh K, Shevitz A, Zaknun D, et al. Age-and time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virus. Pediatr Infect Dis J 1996; 15:1087-91
    • (1996) Pediatr Infect Dis J , vol.15 , pp. 1087-1091
    • McIntosh, K.1    Shevitz, A.2    Zaknun, D.3
  • 4
    • 0033630514 scopus 로고    scopus 로고
    • Maternal and infant factors predicting disease progression in human immunodeficiency virus type 1-infected infants
    • Rich KC, Fowler MG, Mofenson LM, et al. Maternal and infant factors predicting disease progression in human immunodeficiency virus type 1-infected infants. Women and Infants Transmission Study Group. Pediatrics 2000; 105:e8
    • (2000) Women and Infants Transmission Study Group. Pediatrics , vol.105 , pp. e8
    • Rich, K.C.1    Fowler, M.G.2    Mofenson, L.M.3
  • 5
    • 0030728995 scopus 로고    scopus 로고
    • Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations
    • Comans-Bitter WM, de Groot R, van den Beemd R, et al. Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations. J Pediatr 1997; 130:388-93
    • (1997) J Pediatr , vol.130 , pp. 388-393
    • Comans-Bitter, W.M.1    De Groot, R.2    Van Den Beemd, R.3
  • 6
    • 0026569408 scopus 로고
    • Age-related changes in human blood lymphocyte subpopulations
    • Erkeller-Yuksel FM, Deneys V, Yuksel B, et al. Age-related changes in human blood lymphocyte subpopulations. J Pediatr 1992; 120(2 Pt 1): 216-22
    • (1992) J Pediatr , vol.120 , Issue.2 , pp. 216-222
    • Erkeller-Yuksel, F.M.1    Deneys, V.2    Yuksel, B.3
  • 8
    • 9644301110 scopus 로고    scopus 로고
    • Early versus deferred antiretroviral multidrug therapy in infants infected with HIV type 1
    • Faye A, Le Chenadec J, Dollfus C, et al. Early versus deferred antiretroviral multidrug therapy in infants infected with HIV type 1. Clin Infect Dis 2004; 39:1692-8
    • (2004) Clin Infect Dis , vol.39 , pp. 1692-1698
    • Faye, A.1    Le Chenadec, J.2    Dollfus, C.3
  • 9
    • 2942625676 scopus 로고    scopus 로고
    • A trial of three antiretroviral regimens in HIV-1-infected children
    • Luzuriaga K, McManus M, Mofenson L, et al. A trial of three antiretroviral regimens in HIV-1-infected children. N Engl J Med 2004; 350: 2471-80
    • (2004) N Engl J Med , vol.350 , pp. 2471-2480
    • Luzuriaga, K.1    McManus, M.2    Mofenson, L.3
  • 10
    • 56749097184 scopus 로고    scopus 로고
    • Early antiretroviral therapy and mortality among HIV-infected infants
    • Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008; 359: 2233-44
    • (2008) N Engl J Med , vol.359 , pp. 2233-2244
    • Violari, A.1    Cotton, M.F.2    Gibb, D.M.3
  • 11
    • 49849094748 scopus 로고    scopus 로고
    • Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants
    • Prendergast A, Mphatswe W, Tudor-Williams G, et al. Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants. AIDS 2008; 22:1333-43
    • (2008) AIDS , vol.22 , pp. 1333-1343
    • Prendergast, A.1    Mphatswe, W.2    Tudor-Williams, G.3
  • 13
    • 79953060644 scopus 로고    scopus 로고
    • Panel on Antiretroviral Therapy and Medical Management of HIVinfected Children, Accessed 28 June, 2015
    • Panel on Antiretroviral Therapy and Medical Management of HIVinfected Children. Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection. Available at: http://aidsinfo.nih.gov/contentfiles/lvguidelines/pediatricguidelines.pdf. Accessed 28 June 2015
    • Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
  • 14
    • 34247210615 scopus 로고    scopus 로고
    • Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy
    • Persaud D, Ray SC, Kajdas J, et al. Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy. AIDS Res Hum Retroviruses 2007; 23:381-90
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 381-390
    • Persaud, D.1    Ray, S.C.2    Kajdas, J.3
  • 15
    • 9144270766 scopus 로고    scopus 로고
    • Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
    • Persaud D, Siberry GK, Ahonkhai A, et al. Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads. J Virol 2004; 78:968-79
    • (2004) J Virol , vol.78 , pp. 968-979
    • Persaud, D.1    Siberry, G.K.2    Ahonkhai, A.3
  • 16
    • 0028171860 scopus 로고
    • Age-related ranges of memory, activation, and cytotoxic markers on CD4 and CD8 cells in children
    • Aldhous MC, Raab GM, Doherty KV, Mok JY, Bird AG, Froebel KS. Age-related ranges of memory, activation, and cytotoxic markers on CD4 and CD8 cells in children. J Clin Immunol 1994; 14:289-98
    • (1994) J Clin Immunol , vol.14 , pp. 289-298
    • Aldhous, M.C.1    Raab, G.M.2    Doherty, K.V.3    Mok, J.Y.4    Bird, A.G.5    Froebel, K.S.6
  • 17
    • 0242550686 scopus 로고    scopus 로고
    • Lymphocyte subsets in healthy children from birth through 18 years of age: The Pediatric AIDS Clinical Trials Group P1009 study
    • Shearer WT, Rosenblatt HM, Gelman RS, et al. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol 2003; 112: 973-80
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 973-980
    • Shearer, W.T.1    Rosenblatt, H.M.2    Gelman, R.S.3
  • 18
    • 84869765093 scopus 로고    scopus 로고
    • Memory CD4+ CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1
    • Bunders MJ, van der Loos CM, Klarenbeek PL, et al. Memory CD4+ CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1. Blood 2012; 120:4383-90
    • (2012) Blood , vol.120 , pp. 4383-4390
    • Bunders, M.J.1    Van Der Loos, C.M.2    Klarenbeek, P.L.3
  • 19
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 2013; 9:e1003211
    • (2013) PLoS Pathog , vol.9 , pp. e1003211
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 20
    • 84887028999 scopus 로고    scopus 로고
    • Absence of detectable HIV-1 viremia after treatment cessation in an infant
    • Persaud D, Gay H, Ziemniak C, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 2013; 369: 1828-35
    • (2013) N Engl J Med , vol.369 , pp. 1828-1835
    • Persaud, D.1    Gay, H.2    Ziemniak, C.3
  • 21
    • 84859250847 scopus 로고    scopus 로고
    • Impact of multitargeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
    • Ananworanich J, Schuetz A, Vandergeeten C, et al. Impact of multitargeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One 2012; 7:e33948
    • (2012) PLoS One , vol.7 , pp. e33948
    • Ananworanich, J.1    Schuetz, A.2    Vandergeeten, C.3
  • 22
    • 84862189831 scopus 로고    scopus 로고
    • Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
    • Archin NM, Vaidya NK, Kuruc JD, et al. Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection. Proc Natl Acad Sci U S A 2012; 109:9523-8
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 9523-9528
    • Archin, N.M.1    Vaidya, N.K.2    Kuruc, J.D.3
  • 23
    • 84886255436 scopus 로고    scopus 로고
    • The immunological and virological consequences of planned treatment interruptions in children with HIV infection
    • Klein N, Sefe D, Mosconi I, et al. The immunological and virological consequences of planned treatment interruptions in children with HIV infection. PLoS One 2013; 8:e76582
    • (2013) PLoS One , vol.8 , pp. e76582
    • Klein, N.1    Sefe, D.2    Mosconi, I.3
  • 24
    • 84915748829 scopus 로고    scopus 로고
    • The transient HIV remission in the Mississippi baby why is this good news?
    • Ananworanich J, Robb ML. The transient HIV remission in the Mississippi baby: why is this good news? J Int AIDS Soc 2014; 17:19859
    • (2014) J Int AIDS Soc , vol.17 , pp. 19859
    • Ananworanich, J.1    Robb, M.L.2
  • 26
    • 84871709580 scopus 로고    scopus 로고
    • A new tool for the paediatric HIV research: General data from the Cohort of the Spanish Paediatric HIV Network (CoRISpe)
    • de Jose MI, Jimenez de Ory S, Espiau M, et al. A new tool for the paediatric HIV research: general data from the Cohort of the Spanish Paediatric HIV Network (CoRISpe). BMC Infect Dis 2013; 13:2
    • (2013) BMC Infect Dis , vol.13 , pp. 2
    • De Jose, M.I.1    Jimenez De Ory, S.2    Espiau, M.3
  • 28
    • 77950537810 scopus 로고    scopus 로고
    • HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAARTsuppressed subjects
    • Buzon MJ, Massanella M, Llibre JM, et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAARTsuppressed subjects. Nat Med 2010; 16:460-5
    • (2010) Nat Med , vol.16 , pp. 460-465
    • Buzon, M.J.1    Massanella, M.2    Llibre, J.M.3
  • 29
    • 84906771318 scopus 로고    scopus 로고
    • Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients
    • Puertas MC, Salgado M, Moron-Lopez S, et al. Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients. AIDS 2014; 28:2157-9
    • (2014) AIDS , vol.28 , pp. 2157-2159
    • Puertas, M.C.1    Salgado, M.2    Moron-Lopez, S.3
  • 30
    • 0025941011 scopus 로고
    • Confirmation and differentiation of antibodies to human immunodeficiency virus 1 and 2 with a strip-based assay including recombinant antigens and synthetic peptides
    • Pollet DE, Saman EL, Peeters DC, et al. Confirmation and differentiation of antibodies to human immunodeficiency virus 1 and 2 with a strip-based assay including recombinant antigens and synthetic peptides. Clin Chem 1991; 37(10 Pt 1):1700-7
    • (1991) Clin Chem , vol.37 , Issue.10 , pp. 1700-1707
    • Pollet, D.E.1    Saman, E.L.2    Peeters, D.C.3
  • 32
    • 84897553850 scopus 로고    scopus 로고
    • Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children
    • Ananworanich J, Puthanakit T, Suntarattiwong P, et al. Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children. AIDS 2014; 28:1015-20
    • (2014) AIDS , vol.28 , pp. 1015-1020
    • Ananworanich, J.1    Puthanakit, T.2    Suntarattiwong, P.3
  • 33
    • 84885058930 scopus 로고    scopus 로고
    • Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size
    • Jain V, HartogensisW, Bacchetti P, et al. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis 2013; 208: 1202-11
    • (2013) J Infect Dis , vol.208 , pp. 1202-1211
    • Jain, V.1    Hartogensis, W.2    Bacchetti, P.3
  • 34
    • 84864290338 scopus 로고    scopus 로고
    • Dynamics of the resting CD4+ T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age
    • Persaud D, Palumbo PE, Ziemniak C, et al. Dynamics of the resting CD4+ T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age. AIDS 2012; 26:1483-90
    • (2012) AIDS , vol.26 , pp. 1483-1490
    • Persaud, D.1    Palumbo, P.E.2    Ziemniak, C.3
  • 35
    • 84930742652 scopus 로고    scopus 로고
    • Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents
    • Persaud D, Patel K, Karalius B, et al. Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents. JAMA Pediatr 2014; 168: 1138-46
    • (2014) JAMA Pediatr , vol.168 , pp. 1138-1146
    • Persaud, D.1    Patel, K.2    Karalius, B.3
  • 36
    • 84911005930 scopus 로고    scopus 로고
    • HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment
    • Luzuriaga K, Tabak B, Garber M, et al. HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment. J Infect Dis 2014; 210:1529-38
    • (2014) J Infect Dis , vol.210 , pp. 1529-1538
    • Luzuriaga, K.1    Tabak, B.2    Garber, M.3
  • 37
    • 84915800901 scopus 로고    scopus 로고
    • Impact of early initiation of combination antiretroviral therapy on measures of virus in peripheral blood of vertically HIV-1-infected children
    • Melbourne, Australia
    • Brophy J, Chun TW, Samson L, et al. Impact of early initiation of combination antiretroviral therapy on measures of virus in peripheral blood of vertically HIV-1-infected children. In: 20th International AIDS Conference. Melbourne, Australia, 2014
    • (2014) 20th International AIDS Conference
    • Brophy, J.1    Chun, T.W.2    Samson, L.3
  • 38
    • 42149158210 scopus 로고    scopus 로고
    • Early therapy in HIV-1-infected children: Effect on HIV-1 dynamics and HIV-1-specific immune response
    • Zanchetta M, Anselmi A, Vendrame D, et al. Early therapy in HIV-1-infected children: effect on HIV-1 dynamics and HIV-1-specific immune response. Antivir Ther 2008; 13:47-55
    • (2008) Antivir Ther , vol.13 , pp. 47-55
    • Zanchetta, M.1    Anselmi, A.2    Vendrame, D.3
  • 39
    • 84915800900 scopus 로고    scopus 로고
    • No cure of HIV infection in a child despite early treatment and apparent viral clearance
    • Giacomet V, Trabattoni D, Zanchetta N, et al. No cure of HIV infection in a child despite early treatment and apparent viral clearance. Lancet 2014; 384:1320
    • (2014) Lancet , vol.384 , pp. 1320
    • Giacomet, V.1    Trabattoni, D.2    Zanchetta, N.3
  • 40
    • 78149417719 scopus 로고    scopus 로고
    • Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy
    • Yukl SA, Gianella S, Sinclair E, et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis 2010; 202: 1553-61
    • (2010) J Infect Dis , vol.202 , pp. 1553-1561
    • Yukl, S.A.1    Gianella, S.2    Sinclair, E.3


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