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Volumn 4, Issue 2, 2015, Pages 126-141

Molecular methods for somatic mutation testing in lung adenocarcinoma: EGFR and beyond

Author keywords

Anaplastic lymphoma kinase (ALK); Epidermal growth factor receptor (EGFR); RET; ROS1

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN RET; PROTEIN TYROSINE KINASE; RECEPTOR TYROSINE KINASE ROS1; UNCLASSIFIED DRUG;

EID: 84942085066     PISSN: 22186751     EISSN: 22264477     Source Type: Journal    
DOI: 10.3978/j.issn.2218-6751.2015.01.10     Document Type: Review
Times cited : (77)

References (70)
  • 1
    • 84857969863 scopus 로고    scopus 로고
    • Chipping away at the lung cancer genome
    • Pao W, Hutchinson KE. Chipping away at the lung cancer genome. Nat Med 2012;18:349-51.
    • (2012) Nat Med , vol.18 , pp. 349-351
    • Pao, W.1    Hutchinson, K.E.2
  • 2
    • 84960161896 scopus 로고    scopus 로고
    • [Accessed on Jan 13, 2014]
    • Midthun DE. Available online: http://www.uptodate.com/contents/overview-of-the-risk-factors-pathologyand-clinical-manifestations-of-lung-cancer?source=machineLearning&search=lung+cancer&selectedTitle=1%7E150§ionRank=1&anchor=H8#H8. [Accessed on Jan 13, 2014].
    • Midthun, D.E.1
  • 3
    • 85021841538 scopus 로고    scopus 로고
    • My Cancer Genome 2014. [Accessed on Aug 8, 2014]
    • Vnencak-Jones CL, Berger MF, Pao W. Types of Molecular Tumor Testing. My Cancer Genome 2014. Available online: http://www.mycancergenome.org/content/molecular-medicine/types-of-molecular-tumortesting. [Accessed on Aug 8, 2014].
    • Types of Molecular Tumor Testing
    • Vnencak-Jones, C.L.1    Berger, M.F.2    Pao, W.3
  • 5
    • 84960161898 scopus 로고    scopus 로고
    • Cancer Protocols. Available online: http://www.rcpa.edu.au/Library/Practising-Pathology/Structured-Pathology-Reporting-of-Cancer/Cancer-Protocols
  • 6
    • 84879290901 scopus 로고    scopus 로고
    • Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
    • Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Mol Diagn 2013;15:415-53.
    • (2013) J Mol Diagn , vol.15 , pp. 415-453
    • Lindeman, N.I.1    Cagle, P.T.2    Beasley, M.B.3
  • 7
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014;511:543-50.
    • (2014) Nature , vol.511 , pp. 543-550
  • 8
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004;101:13306-11.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 9
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 10
    • 84874644488 scopus 로고    scopus 로고
    • Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in lung cancers
    • Yu HA, Riely GJ. Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in lung cancers. J Natl Compr Canc Netw 2013;11:161-9.
    • (2013) J Natl Compr Canc Netw , vol.11 , pp. 161-169
    • Yu, H.A.1    Riely, G.J.2
  • 11
    • 84939780811 scopus 로고    scopus 로고
    • Second generation tyrosine kinase inhibitors for the treatment of metastatic non-small-cell lung cancer
    • Stasi I, Cappuzzo F. Second generation tyrosine kinase inhibitors for the treatment of metastatic non-small-cell lung cancer. Transl Respir Med 2014;2:2.
    • (2014) Transl Respir Med , vol.2 , pp. 2
    • Stasi, I.1    Cappuzzo, F.2
  • 12
    • 79551563284 scopus 로고    scopus 로고
    • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011;6:244-85.
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3
  • 13
    • 84904513918 scopus 로고    scopus 로고
    • Associations between mutations and histologic patterns of mucin in lung adenocarcinoma: invasive mucinous pattern and extracellular mucin are associated with KRAS mutation
    • Kadota K, Yeh YC, D'Angelo SP, et al. Associations between mutations and histologic patterns of mucin in lung adenocarcinoma: invasive mucinous pattern and extracellular mucin are associated with KRAS mutation. Am J Surg Pathol 2014;38:1118-27.
    • (2014) Am J Surg Pathol , vol.38 , pp. 1118-1127
    • Kadota, K.1    Yeh, Y.C.2    D'Angelo, S.P.3
  • 14
    • 84949176348 scopus 로고    scopus 로고
    • Molecular Pathology of Lung Cancers
    • Cheng L, Eble JN. eds. First Edition
    • Scholl LM, Lindeman NI. Molecular Pathology of Lung Cancers. In: Cheng L, Eble JN. eds. Molecular Surgical Pathology. First Edition 2013:83-94.
    • (2013) Molecular Surgical Pathology , pp. 83-94
    • Scholl, L.M.1    Lindeman, N.I.2
  • 15
    • 84890018871 scopus 로고    scopus 로고
    • Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer
    • Gainor JF, Shaw AT. Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer. J Clin Oncol 2013;31:3987-96.
    • (2013) J Clin Oncol , vol.31 , pp. 3987-3996
    • Gainor, J.F.1    Shaw, A.T.2
  • 16
    • 77953291664 scopus 로고    scopus 로고
    • The biology and treatment of EML4-ALK non-small cell lung cancer
    • Sasaki T, Rodig SJ, Chirieac LR, et al. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010;46:1773-80.
    • (2010) Eur J Cancer , vol.46 , pp. 1773-1780
    • Sasaki, T.1    Rodig, S.J.2    Chirieac, L.R.3
  • 17
    • 84894563860 scopus 로고    scopus 로고
    • HIP1-ALK, a novel ALK fusion variant that responds to crizotinib
    • Fang DD, Zhang B, Gu Q, et al. HIP1-ALK, a novel ALK fusion variant that responds to crizotinib. J Thorac Oncol 2014;9:285-94.
    • (2014) J Thorac Oncol , vol.9 , pp. 285-294
    • Fang, D.D.1    Zhang, B.2    Gu, Q.3
  • 18
    • 84856695102 scopus 로고    scopus 로고
    • KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only
    • Togashi Y, Soda M, Sakata S, et al. KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only. PloS One 2012;7:e31323.
    • (2012) PloS One , vol.7
    • Togashi, Y.1    Soda, M.2    Sakata, S.3
  • 19
    • 84878783802 scopus 로고    scopus 로고
    • Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing
    • Majewski IJ, Mittempergher L, Davidson NM, et al. Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing. J Pathol 2013;230:270-6.
    • (2013) J Pathol , vol.230 , pp. 270-276
    • Majewski, I.J.1    Mittempergher, L.2    Davidson, N.M.3
  • 20
    • 84862790522 scopus 로고    scopus 로고
    • Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing
    • Jung Y, Kim P, Jung Y, et al. Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing. Genes Chromosomes Cancer 2012;51:590-7.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 590-597
    • Jung, Y.1    Kim, P.2    Jung, Y.3
  • 21
    • 84904618807 scopus 로고    scopus 로고
    • A Systemic Review of Resistance Mechanisms and Ongoing Clinical Trials in ALK-Rearranged Non-Small Cell Lung Cancer
    • Esfahani K, Agulnik JS, Cohen V. A Systemic Review of Resistance Mechanisms and Ongoing Clinical Trials in ALK-Rearranged Non-Small Cell Lung Cancer. Front Oncol 2014;4:174.
    • (2014) Front Oncol , vol.4 , pp. 174
    • Esfahani, K.1    Agulnik, J.S.2    Cohen, V.3
  • 22
    • 84881245421 scopus 로고    scopus 로고
    • Molecular pathways: ROS1 fusion proteins in cancer
    • Davies KD, Doebele RC. Molecular pathways: ROS1 fusion proteins in cancer. Clin Cancer Res 2013;19:4040-5.
    • (2013) Clin Cancer Res , vol.19 , pp. 4040-4045
    • Davies, K.D.1    Doebele, R.C.2
  • 23
    • 84926520800 scopus 로고    scopus 로고
    • Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma
    • [Epub ahead of print]
    • Lee SE, Lee B, Hong M, et al. Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma. Mod Pathol 2014. [Epub ahead of print].
    • (2014) Mod Pathol
    • Lee, S.E.1    Lee, B.2    Hong, M.3
  • 24
    • 84857985225 scopus 로고    scopus 로고
    • RET, ROS1 and ALK fusions in lung cancer
    • Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med 2012;18:378-81.
    • (2012) Nat Med , vol.18 , pp. 378-381
    • Takeuchi, K.1    Soda, M.2    Togashi, Y.3
  • 25
    • 84863338079 scopus 로고    scopus 로고
    • ROS1 rearrangements define a unique molecular class of lung cancers
    • Bergethon K, Shaw AT, Ou SH, et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012;30:863-70.
    • (2012) J Clin Oncol , vol.30 , pp. 863-870
    • Bergethon, K.1    Shaw, A.T.2    Ou, S.H.3
  • 26
    • 84875224942 scopus 로고    scopus 로고
    • ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases
    • Yoshida A, Kohno T, Tsuta K, et al. ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases. Am J Surg Pathol 2013;37:554-62.
    • (2013) Am J Surg Pathol , vol.37 , pp. 554-562
    • Yoshida, A.1    Kohno, T.2    Tsuta, K.3
  • 27
    • 84865089246 scopus 로고    scopus 로고
    • Analysis of receptor tyrosine kinase ROS1-positive tumors in nonsmall cell lung cancer: identification of a FIG-ROS1 fusion
    • Rimkunas VM, Crosby KE, Li D, et al. Analysis of receptor tyrosine kinase ROS1-positive tumors in nonsmall cell lung cancer: identification of a FIG-ROS1 fusion. Clin Cancer Res 2012;18:4449-57.
    • (2012) Clin Cancer Res , vol.18 , pp. 4449-4457
    • Rimkunas, V.M.1    Crosby, K.E.2    Li, D.3
  • 28
    • 84871181092 scopus 로고    scopus 로고
    • Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNAbased screen for tyrosine kinase fusions
    • Suehara Y, Arcila M, Wang L, et al. Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNAbased screen for tyrosine kinase fusions. Clin Cancer Res 2012;18:6599-608.
    • (2012) Clin Cancer Res , vol.18 , pp. 6599-6608
    • Suehara, Y.1    Arcila, M.2    Wang, L.3
  • 29
    • 84899989532 scopus 로고    scopus 로고
    • Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers
    • Yoshida A, Tsuta K, Wakai S, et al. Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers. Mod Pathol 2014;27:711-20.
    • (2014) Mod Pathol , vol.27 , pp. 711-720
    • Yoshida, A.1    Tsuta, K.2    Wakai, S.3
  • 30
    • 84866434919 scopus 로고    scopus 로고
    • Genomic landscape of non-small cell lung cancer in smokers and neversmokers
    • Govindan R, Ding L, Griffith M, et al. Genomic landscape of non-small cell lung cancer in smokers and neversmokers. Cell 2012;150:1121-34.
    • (2012) Cell , vol.150 , pp. 1121-1134
    • Govindan, R.1    Ding, L.2    Griffith, M.3
  • 31
    • 84911372597 scopus 로고    scopus 로고
    • Crizotinib in ROS1-Rearranged Non-Small-Cell Lung Cancer
    • Shaw AT, Ou SH, Bang YJ, et al. Crizotinib in ROS1-Rearranged Non-Small-Cell Lung Cancer. N Engl J Med 2014;371:1963-71.
    • (2014) N Engl J Med , vol.371 , pp. 1963-1971
    • Shaw, A.T.1    Ou, S.H.2    Bang, Y.J.3
  • 32
    • 84886787498 scopus 로고    scopus 로고
    • RET fusion gene: translation to personalized lung cancer therapy
    • Kohno T, Tsuta K, Tsuchihara K, et al. RET fusion gene: translation to personalized lung cancer therapy. Cancer Sci 2013;104:1396-400.
    • (2013) Cancer Sci , vol.104 , pp. 1396-1400
    • Kohno, T.1    Tsuta, K.2    Tsuchihara, K.3
  • 33
    • 84878858856 scopus 로고    scopus 로고
    • Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas
    • Drilon A, Wang L, Hasanovic A, et al. Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas. Cancer Discov 2013;3:630-5.
    • (2013) Cancer Discov , vol.3 , pp. 630-635
    • Drilon, A.1    Wang, L.2    Hasanovic, A.3
  • 35
    • 84878878783 scopus 로고    scopus 로고
    • The new kid on the block: RET in lung cancer
    • Gainor JF, Shaw AT. The new kid on the block: RET in lung cancer. Cancer Discov 2013;3:604-6.
    • (2013) Cancer Discov , vol.3 , pp. 604-606
    • Gainor, J.F.1    Shaw, A.T.2
  • 36
    • 84884986372 scopus 로고    scopus 로고
    • Molecular genetic testing for lung adenocarcinomas: a practical approach to clinically relevant mutations and translocations
    • Dacic S. Molecular genetic testing for lung adenocarcinomas: a practical approach to clinically relevant mutations and translocations. J Clin Pathol 2013;66:870-4.
    • (2013) J Clin Pathol , vol.66 , pp. 870-874
    • Dacic, S.1
  • 37
    • 84901604272 scopus 로고    scopus 로고
    • Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing
    • Wong SQ, Li J, Tan AY, et al. Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing. BMC Med Genomics 2014;7:23.
    • (2014) BMC Med Genomics , vol.7 , pp. 23
    • Wong, S.Q.1    Li, J.2    Tan, A.Y.3
  • 38
    • 84890615358 scopus 로고    scopus 로고
    • Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours
    • Wong SQ, Li J, Salemi R, et al. Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours. Sci Rep 2013;3:3494.
    • (2013) Sci Rep , vol.3 , pp. 3494
    • Wong, S.Q.1    Li, J.2    Salemi, R.3
  • 39
    • 84883178389 scopus 로고    scopus 로고
    • Functional DNA quantification guides accurate next-generation sequencing mutation detection in formalin-fixed, paraffin-embedded tumor biopsies
    • Sah S, Chen L, Houghton J, et al. Functional DNA quantification guides accurate next-generation sequencing mutation detection in formalin-fixed, paraffin-embedded tumor biopsies. Genome Med 2013;5:77.
    • (2013) Genome Med , vol.5 , pp. 77
    • Sah, S.1    Chen, L.2    Houghton, J.3
  • 40
    • 84874606355 scopus 로고    scopus 로고
    • EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples
    • Ellison G, Zhu G, Moulis A, et al. EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples. J Clin Pathol 2013;66:79-89.
    • (2013) J Clin Pathol , vol.66 , pp. 79-89
    • Ellison, G.1    Zhu, G.2    Moulis, A.3
  • 41
    • 84960161899 scopus 로고    scopus 로고
    • [cited 2014 Dec 1]
    • Archer™ ALK, RET, ROS1 v2 Panel. Enzymatics;2014. [cited 2014 Dec 1]. Available online: http://www.enzymatics.com/wp-content/uploads/2014/01/Archer_Brochure_2014.pdf
    • (2014)
  • 43
    • 84875937242 scopus 로고    scopus 로고
    • Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies
    • Li T, Kung HJ, Mack PC, et al. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol 2013;31:1039-49.
    • (2013) J Clin Oncol , vol.31 , pp. 1039-1049
    • Li, T.1    Kung, H.J.2    Mack, P.C.3
  • 45
    • 52949096084 scopus 로고    scopus 로고
    • Next-generation DNA sequencing methods
    • Mardis ER. Next-generation DNA sequencing methods. Annu Rev Genomics Hum Genet 2008;9:387-402.
    • (2008) Annu Rev Genomics Hum Genet , vol.9 , pp. 387-402
    • Mardis, E.R.1
  • 46
    • 84855564475 scopus 로고    scopus 로고
    • Next-generation sequencing for cancer diagnostics: a practical perspective
    • Meldrum C, Doyle MA, Tothill RW. Next-generation sequencing for cancer diagnostics: a practical perspective. Clin Biochem Rev 2011;32:177-95.
    • (2011) Clin Biochem Rev , vol.32 , pp. 177-195
    • Meldrum, C.1    Doyle, M.A.2    Tothill, R.W.3
  • 47
    • 84905858372 scopus 로고    scopus 로고
    • Next-generation sequencing: a change of paradigm in molecular diagnostic validation
    • Salto-Tellez M, Gonzalez de Castro D. Next-generation sequencing: a change of paradigm in molecular diagnostic validation. J Pathol 2014;234:5-10.
    • (2014) J Pathol , vol.234 , pp. 5-10
    • Salto-Tellez, M.1    Gonzalez de Castro, D.2
  • 49
    • 84960161901 scopus 로고    scopus 로고
    • Available online: http://agenabio.com/sites/default/files/41-20013R1.0-LungCarta-Flyer.pdf
  • 50
    • 84908461791 scopus 로고    scopus 로고
    • (In Vitro and Imaging Tools)
    • FDA. List of Cleared or Approved Companion Diagnostic Devices (In Vitro and Imaging Tools). Available online: http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/InVitroDiagnostics/ucm301431.htm
    • List of Cleared or Approved Companion Diagnostic Devices
  • 51
    • 84960121693 scopus 로고    scopus 로고
    • cobas® EGFR Mutation Test for in vitro diagnostic use. Roche Molecular Systems Inc., 2013. Available online: http://www.accessdata.fda.gov/cdrh_docs/pdf12/P120019c.pdf
    • (2013) Roche Molecular Systems Inc
  • 52
    • 84960161902 scopus 로고    scopus 로고
    • therascreen® EGFR RGQ PCR Kit Instructions for Use (Handbook), 2013. Available online: http://www.accessdata.fda.gov/cdrh_docs/pdf12/P120022c.pdf
    • (2013)
  • 54
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13:239-46.
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 55
    • 84884736973 scopus 로고    scopus 로고
    • Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
    • Sequist LV, Yang JC, Yamamoto N, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013;31:3327-34.
    • (2013) J Clin Oncol , vol.31 , pp. 3327-3334
    • Sequist, L.V.1    Yang, J.C.2    Yamamoto, N.3
  • 56
    • 79960702788 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Fukuoka M, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. J Clin Oncol 2011;29:2866-74.
    • (2011) J Clin Oncol , vol.29 , pp. 2866-2874
    • Fukuoka, M.1    Wu, Y.L.2    Thongprasert, S.3
  • 57
    • 84896939264 scopus 로고    scopus 로고
    • National Working Group Meeting on ALK diagnostics in lung cancer
    • Cooper W, Fox S, O'Toole S, et al. National Working Group Meeting on ALK diagnostics in lung cancer. Asia Pac J Clin Oncol 2014;10 Suppl 2:11-17.
    • (2014) Asia Pac J Clin Oncol , vol.10 , pp. 11-17
    • Cooper, W.1    Fox, S.2    O'Toole, S.3
  • 59
    • 84867395679 scopus 로고    scopus 로고
    • EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations
    • Thunnissen E, Bubendorf L, Dietel M, et al. EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations. Virchows Arch 2012;461:245-57.
    • (2012) Virchows Arch , vol.461 , pp. 245-257
    • Thunnissen, E.1    Bubendorf, L.2    Dietel, M.3
  • 60
    • 84889078337 scopus 로고    scopus 로고
    • Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization
    • Selinger CI, Rogers TM, Russell PA, et al. Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol 2013;26:1545-53.
    • (2013) Mod Pathol , vol.26 , pp. 1545-1553
    • Selinger, C.I.1    Rogers, T.M.2    Russell, P.A.3
  • 61
    • 84920523851 scopus 로고    scopus 로고
    • Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH
    • Hutarew G, Hauser-Kronberger C, Strasser F, et al. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. Histopathology 2014;65:398-407.
    • (2014) Histopathology , vol.65 , pp. 398-407
    • Hutarew, G.1    Hauser-Kronberger, C.2    Strasser, F.3
  • 63
    • 84960161904 scopus 로고    scopus 로고
    • [Accessed on Aug 24, 2014]
    • ESP Lung External Quality Assessment Scheme. Available online: http://lung.eqascheme.org/. [Accessed on Aug 24, 2014].
  • 64
    • 84882831490 scopus 로고    scopus 로고
    • EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma
    • Cooper WA, Yu B, Yip PY, et al. EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. J Clin Pathol 2013;66:744-8.
    • (2013) J Clin Pathol , vol.66 , pp. 744-748
    • Cooper, W.A.1    Yu, B.2    Yip, P.Y.3
  • 65
    • 77649140830 scopus 로고    scopus 로고
    • Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR
    • Brevet M, Arcila M, Ladanyi M. Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR. J Mol Diagn 2010;12:169-76.
    • (2010) J Mol Diagn , vol.12 , pp. 169-176
    • Brevet, M.1    Arcila, M.2    Ladanyi, M.3
  • 66
    • 84884211534 scopus 로고    scopus 로고
    • Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer
    • Lira ME, Kim TM, Huang D, et al. Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn 2013;15:51-61.
    • (2013) J Mol Diagn , vol.15 , pp. 51-61
    • Lira, M.E.1    Kim, T.M.2    Huang, D.3
  • 67
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-83.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3
  • 68
    • 84894066256 scopus 로고    scopus 로고
    • A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer
    • Lira ME, Choi YL, Lim SM, et al. A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer. J Mol Diagn 2014;16:229-43.
    • (2014) J Mol Diagn , vol.16 , pp. 229-243
    • Lira, M.E.1    Choi, Y.L.2    Lim, S.M.3
  • 69
    • 84898542288 scopus 로고    scopus 로고
    • Liquid biopsies: genotyping circulating tumor DNA
    • Diaz LA Jr, Bardelli A. Liquid biopsies: genotyping circulating tumor DNA. J Clin Oncol 2014;32:579-86.
    • (2014) J Clin Oncol , vol.32 , pp. 579-586
    • Diaz, L.A.1    Bardelli, A.2
  • 70
    • 84904061727 scopus 로고    scopus 로고
    • Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA
    • Haber DA, Velculescu VE. Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA. Cancer Discov 2014;4:650-61.
    • (2014) Cancer Discov , vol.4 , pp. 650-661
    • Haber, D.A.1    Velculescu, V.E.2


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