The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma

Applied Microbiology and Biotechnology

Volumn 99, Issue 20, 2015, Pages 8487-8494

  Lin, Chen ^a   Wang, Ziyu ^b,c   Li, Li ^a   He, Yong ^d   Fan, Jiajun ^b   Liu, Zhongyu ^a   Zhao, Shuwei ^a   Ju, Dianwen ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c Shanghai Institute of Pharmaceutical Industry   (China)

^d NINGBO UNIVERSITY   (China)

Author keywords

Autophagy; Cytotoxicity; Laryngeal squamous cell carcinoma; Recombinant human arginase

Indexed keywords

AMINO ACIDS; CELLS; CHEMICAL COMPOUNDS; CYTOTOXICITY; TUMORS;

AUTOPHAGY; DEPRIVATION THERAPY; MALIGNANT TUMORS; RECOMBINANT HUMAN ARGINASE; SIGNALING PATHWAYS; SQUAMOUS CARCINOMA; SQUAMOUS CELL CARCINOMA; TIME DEPENDENT;

CYTOLOGY;

ARGINASE; BAFILOMYCIN A1; CHLOROQUINE; CYTOTOXIC AGENT; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; RECOMBINANT ENZYME; RECOMBINANT HUMAN ARGINASE; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

CARCINOGEN; ENZYME ACTIVITY; INHIBITOR; MORTALITY; RECOMBINATION; TOXICITY; TUMOR;

A549 CELL LINE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER INHIBITION; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; LARYNGEAL CANCER CELL LINE; LARYNGEAL SQUAMOUS CELL CARCINOMA; LARYNX CARCINOMA; LIGHT CHAIN; MTT ASSAY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL LINE; UPREGULATION; CELL SURVIVAL; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; PHYSIOLOGY; TUMOR CELL LINE;

ARGINASE; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; EPITHELIAL CELLS; HUMANS; RECOMBINANT PROTEINS;

EID: 84941994651     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-015-6565-6     Document Type: Article

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