Different stability and proteasome-mediated degradation rate of SMN protein isoforms

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Locatelli, Denise ^a   Terao, Mineko ^b   Kurosaki, Mami ^b   Zanellati, Maria Clara ^a   Pletto, Daniela Rita ^a   Finardi, Adele ^a   Colciaghi, Francesca ^a   Garattini, Enrico ^b   Battaglia, Giorgio Stefano ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; PROTEASOME; SURVIVAL MOTOR NEURON PROTEIN; SMN1 PROTEIN, HUMAN; SURVIVAL MOTOR NEURON PROTEIN 1; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; COMPLEX FORMATION; CONTROLLED STUDY; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; INTRACELLULAR SIGNALING; MOTONEURON; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; WESTERN BLOTTING; CELL LINE; GENETICS; METABOLISM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; SPINAL MUSCULAR ATROPHY;

CELL LINE; HUMANS; MUSCULAR ATROPHY, SPINAL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ISOFORMS; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; SURVIVAL OF MOTOR NEURON 1 PROTEIN; UBIQUITIN;

EID: 84941929719     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134163     Document Type: Article

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