Total Synthesis and Biological Evaluation of Ipomoeassin F and Its Unnatural 11R-Epimer

Journal of Organic Chemistry

Volumn 80, Issue 18, 2015, Pages 9279-9291

  Zong, Guanghui ^a   Barber, Eric ^a   Aljewari, Hazim ^a   Zhou, Jianhong ^a   Hu, Zhijian ^a   Du, Yuchun ^a   Shi, Wei Q ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DRUG PRODUCTS;

APOPTOSIS ASSAYS; BIOLOGICAL EVALUATION; CELL CYCLE ANALYSIS; CHEMOTHERAPEUTIC DRUGS; CYTOTOXICITY ASSAYS; DRUG DEVELOPMENT; MECHANISM OF FUNCTIONS; PROTEIN FUNCTIONS;

BIOSYNTHESIS;

ANTINEOPLASTIC AGENT; CARBOHYDRATE; DISACCHARIDE; HYDROXYL GROUP; IPOMOEASSIN F; MACROLIDE; PACLITAXEL; UNCLASSIFIED DRUG; GLYCOCONJUGATE; GLYCOLIPID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS ASSAY; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DRUG CONFORMATION; DRUG SCREENING; DRUG SYNTHESIS; EPIMER; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN FUNCTION; STEREOCHEMISTRY; APOPTOSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCOCONJUGATES; GLYCOLIPIDS; HUMANS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84941914895     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/acs.joc.5b01765     Document Type: Article

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