DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing

Journal of Cranio-Maxillofacial Surgery

Volumn 43, Issue 8, 2015, Pages 1494-1500

  Morandi, Luca ^a   Gissi, Davide ^a   Tarsitano, Achille ^a   Asioli, Sofia ^a   Monti, Valentina ^a   Del Corso, Giacomo ^a   Marchetti, Claudio ^a   Montebugnoli, Lucio ^a   Foschini, Maria Pia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

DNA methylation; Next generation sequencing; Oral scraping; Oral squamous cell carcinoma

Indexed keywords

BISULFITE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; FIZZY RELATED PROTEIN; MICRORNA; MICRORNA 137; MICRORNA 357; PROTEIN GP1BB; PROTEIN KIF1A; PROTEIN KINASE ZAP 70; PROTEIN P16; PROTEIN P53; UNCLASSIFIED DRUG; ADHESION RECEPTOR; CADHERIN; CDH1 PROTEIN, HUMAN; HYDROGEN SULFITE; KINESIN; MIRN137 MICRORNA, HUMAN; MIRN375 MICRORNA, HUMAN; SULFITE; THROMBIN RECEPTOR; TP53 PROTEIN, HUMAN; ZAP70 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER GRADING; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA DETERMINATION; DNA METHYLATION; DNA SEQUENCE; EARLY DIAGNOSIS; FEMALE; GENE MUTATION; HIGH GADE ORAL SQUAMOUS INTRAEPITHELIAL LESION; HUMAN; HUMAN TISSUE; LICHEN PLANUS; LOW GRADE ORAL SQUAMOUS INTRAEPITHELIAL LESION; MALE; MIDDLE AGED; MOUTH LESION; MOUTH SQUAMOUS CELL CARCINOMA; NEXT GENERATION SEQUENCING; SMOKING; STATISTICAL SIGNIFICANCE; TOOTH BRUSHING; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; COHORT ANALYSIS; CYTODIAGNOSIS; EARLY CANCER DIAGNOSIS; EXON; GENETICS; MOUTH NEOPLASMS; MUTATION; PROCEDURES; PROMOTER REGION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CADHERINS; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYTODIAGNOSIS; DNA METHYLATION; EARLY DETECTION OF CANCER; EXONS; FEMALE; HUMANS; KINESIN; LICHEN PLANUS, ORAL; MALE; MICRORNAS; MIDDLE AGED; MOUTH NEOPLASMS; MUTATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; SULFITES; TUMOR SUPPRESSOR PROTEIN P53; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84941908020     PISSN: 10105182     EISSN: 18784119     Source Type: Journal    
DOI: 10.1016/j.jcms.2015.07.028     Document Type: Article

References (47)

1. N. Acciarri, R. Padovani, M.P. Foschini, M. Giulioni, and F.S. Finizio Intracranial squamous cell carcinoma arising in an epidermoid cyst Br J Neurosurg 7 5 1993 565 569
2. S. Amin, A. Parker, and J. Mann ZAP70 in chronic lymphocytic leukaemia Int J Biochem Cell Biol 40 9 2008 1654 1658
3. T. Ando, T. Yoshida, S. Enomoto, K. Asada, M. Tatematsu, M. Ichinose, and et al. DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect Int J Cancer 124 10 2009 2367 2374
4. E. Bandres, X. Agirre, N. Bitarte, N. Ramirez, R. Zarate, J. Roman-Gomez, and et al. Epigenetic regulation of microRNA expression in colorectal cancer Int J Cancer 125 11 2009 2737 2743
5. N. Bediaga, X. Marichalar-Mendia, J.M. Aguirre-Urizar, B. Calvo, M.A. Echebarria-Goicouria, M.M. de Pancorbo, and et al. Global DNA methylation: uncommon event in oral lichenoid disease Oral Dis 20 8 2014 821 826
6. B.J. Braakhuis, M.P. Tabor, C.R. Leemans, I. van der Waal, G.B. Snow, and R.H. Brakenhoff Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions Head Neck 24 2 2002 198 206
7. J. Cao, J. Zhou, Y. Gao, L. Gu, H. Meng, H. Liu, and et al. Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study Clin Cancer Res 15 16 2009 5178 5183
8. R. Claus, D.M. Lucas, S. Stilgenbauer, A.S. Ruppert, L. Yu, M. Zucknick, and et al. Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia J Clin Oncol 30 20 2012 2483 2491
9. R. Claus, D.M. Lucas, A.S. Ruppert, K.E. Williams, D. Weng, K. Patterson, and et al. Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia Blood 124 1 2014 42 48
10. J. Dang, Y.Q. Bian, J.Y. Sun, F. Chen, G.Y. Dong, Q. Liu, and et al. MicroRNA-137 promoter methylation in oral lichen planus and oral squamous cell carcinoma J Oral Pathol Med 42 4 2013 315 321
11. C. De Smet, and A. Loriot DNA hypomethylation and activation of germline-specific genes in cancer Adv Exp Med Biol 754 2013 149 166
12. S. Demokan, X. Chang, A. Chuang, W.K. Mydlarz, J. Kaur, P. Huang, and et al. KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses Int J Cancer 127 10 2010 2351 2359
13. N. Gale, R. Blagus, S.K. El-Mofty, T. Helliwell, M.L. Prasad, A. Sandison, and et al. Evaluation of a new grading system for laryngeal squamous intraepithelial lesions-a proposed unified classification Histopathology 65 4 2014 456 464
14. J.A. Gasche, and A. Goel Epigenetic mechanisms in oral carcinogenesis Future Oncol 8 11 2012 1407 1425
15. M. Hasegawa, H.H. Nelson, E. Peters, E. Ringstrom, M. Posner, and K.T. Kelsey Patterns of gene promoter methylation in squamous cell cancer of the head and neck Oncogene 21 27 2002 4231 4236
16. P.V. Jithesh, J.M. Risk, A.G. Schache, J. Dhanda, B. Lane, T. Liloglou, and et al. The epigenetic landscape of oral squamous cell carcinoma Br J Cancer 108 2 2013 370 379
17. J. Kagan, S. Srivastava, P.E. Barker, S.A. Belinsky, and P. Cairns Towards clinical application of methylated DNA sequences as cancer biomarkers: a joint NCI's EDRN and NIST workshop on standards, methods, assays, reagents and tools Cancer Res 67 10 2007 4545 4549
18. K. Kato, A. Hara, T. Kuno, H. Mori, T. Yamashita, M. Toida, and et al. Aberrant promoter hypermethylation of p16 and MGMT genes in oral squamous cell carcinomas and the surrounding normal mucosa J Cancer Res Clin Oncol 132 11 2006 735 743
19. G.H. Khor, G.R. Froemming, R.B. Zain, M.T. Abraham, E. Omar, S.K. Tan, and et al. DNA methylation profiling revealed promoter hypermethylation-induced silencing of p16, DDAH2 and DUSP1 in primary oral squamous cell carcinoma Int J Med Sci 10 12 2013 1727 1739
20. D.M. Kordi-Tamandani, A.K. Moazeni-Roodi, M.A. Rigi-Ladiz, M. Hashemi, E. Birjandian, and A. Torkamanzehi Promoter hypermethylation and expression profile of MGMT and CDH1 genes in oral cavity cancer Arch Oral Biol 55 10 2010 809 814
21. K. Kozaki, I. Imoto, S. Mogi, K. Omura, and J. Inazawa Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer Cancer Res 68 7 2008 2094 2105
22. Y. Kumaki, M. Oda, and M. Okano QUMA: quantification tool for methylation analysis Nucleic Acids Res 36 Web server issue 2008 W170 W175
23. S.M. Langevin, R.A. Stone, C.H. Bunker, J.R. Grandis, R.W. Sobol, and E. Taioli MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index Carcinogenesis 31 5 2010 864 870
24. L.C. Li, and R. Dahiya MethPrimer: designing primers for methylation PCRs Bioinformatics 18 11 2002 1427 1431
25. A.M. Lim, I.L. Candiloro, N. Wong, M. Collins, H. Do, E.A. Takano, and et al. Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome Clin Epigenetics 6 1 2014 Dec 9 22 10.1186/1868-7083-6-22 eCollection 2014
26. M. Lopez, J.M. Aguirre, N. Cuevas, M. Anzola, J. Videgain, J. Aguirregaviria, and et al. Gene promoter hypermethylation in oral rinses of leukoplakia patients - a diagnostic and/or prognostic tool? Eur J Cancer 39 16 2003 2306 2309
27. C.J. Marsit, B.C. Christensen, E.A. Houseman, M.R. Karagas, M.R. Wrensch, R.F. Yeh, and et al. Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma Carcinogenesis 30 3 2009 416 422
28. M. Mascolo, M. Siano, G. Ilardi, D. Russo, F. Merolla, G. De Rosa, and et al. Epigenetic disregulation in oral cancer Int J Mol Sci 13 2 2012 2331 2353
29. M.D. Mignogna, S. Fedele, and L. Lo Russo The World Cancer Report and the burden of oral cancer Eur J Cancer Prev 13 2 2004 139 142
30. L. Morandi, E. Franceschi, D. de Biase, G. Marucci, A. Tosoni, M. Ermani, and et al. Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference BMC Cancer 10 2010 48
31. L. Morandi, A. Tarsitano, D. Gissi, E. Leonardi, T. Balbi, C. Marchetti, and et al. Clonality analysis in primary oral squamous cell carcinoma and related lymph-node metastasis revealed by TP53 and mitochondrial DNA next generation sequencing analysis J Craniomaxillofac Surg 43 2 2015 208 213
32. S. Nagata, T. Hamada, N. Yamada, S. Yokoyama, S. Kitamoto, Y. Kanmura, and et al. Aberrant DNA methylation of tumor-related genes in oral rinse: a noninvasive method for detection of oral squamous cell carcinoma Cancer 118 17 2012 4298 4308
33. Y. Okada, H. Yamazaki, Y. Sekine-Aizawa, and N. Hirokawa The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors Cell 81 5 1995 769 780
34. K.M. Pattani, Z. Zhang, S. Demokan, C. Glazer, M. Loyo, S. Goodman, and et al. Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy Cancer Prev Res (Phila) 3 9 2010 1093 1103
35. S.L. Rosas, W. Koch, M.G. da Costa Carvalho, L. Wu, J. Califano, W. Westra, and et al. Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients Cancer Res 61 3 2001 939 942
36. M. Sanchez-Cespedes, M. Esteller, L. Wu, H. Nawroz-Danish, G.H. Yoo, W.M. Koch, and et al. Gene promoter hypermethylation in tumors and serum of head and neck cancer patients Cancer Res 60 4 2000 892 895
37. A. Savoia, A. Pastore, D. De Rocco, E. Civaschi, M. Di Stazio, R. Bottega, and et al. Clinical and genetic aspects of Bernard-Soulier syndrome: searching for genotype/phenotype correlations Haematologica 96 3 2011 417 423
38. M. Sawhney, N. Rohatgi, J. Kaur, S.D. Gupta, S.V. Deo, N.K. Shukla, and et al. MGMT expression in oral precancerous and cancerous lesions: correlation with progression, nodal metastasis and poor prognosis Oral Oncol 43 5 2007 515 522
39. J. Schussel, X.C. Zhou, Z. Zhang, K. Pattani, F. Bermudez, G. Jean-Charles, and et al. EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions Clin Cancer Res 19 12 2013 3268 3275
40. R. Shaw The epigenetics of oral cancer Int J Oral Maxillofac Surg 35 2 2006 101 108
41. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics CA Cancer J Clin 2013 63 1 2013 11 30
42. J. Silber, D.A. Lim, C. Petritsch, A.I. Persson, A.K. Maunakea, M. Yu, and et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells BMC Med 6 2008 14
43. P.F. Su, W.L. Huang, H.T. Wu, C.H. Wu, T.Y. Liu, and S.Y. Kao p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner Oral Oncol 46 10 2010 734 739
44. M. Takeshima, M. Saitoh, K. Kusano, H. Nagayasu, Y. Kurashige, M. Malsantha, and et al. High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka J Oral Pathol Med 37 8 2008 475 479
45. L. Thompson World Health Organization classification of tumours: pathology and genetics of head and neck tumours Ear Nose Throat J 85 2 2006 74
46. R. Towle, D. Truong, K. Hogg, W.P. Robinson, C.F. Poh, and C. Garnis Global analysis of DNA methylation changes during progression of oral cancer Oral Oncol 49 11 2013 1033 1042
47. C.T. Viet, R.C. Jordan, and B.L. Schmidt DNA promoter hypermethylation in saliva for the early diagnosis of oral cancer J Calif Dent Assoc 35 12 2007 844 849