메뉴 건너뛰기




Volumn 10, Issue , 2010, Pages

Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: Detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference

Author keywords

[No Author keywords available]

Indexed keywords

6 O METHYLGUANINE; BISULFITE; DNA METHYLTRANSFERASE; GENE PRODUCT; LOCKED NUCLEIC ACID; PROTEIN SNURF; TEMOZOLOMIDE; UNCLASSIFIED DRUG; ALKYLATING AGENT; CARMUSTINE; DACARBAZINE; DRUG DERIVATIVE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

EID: 77949460376     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-48     Document Type: Article
Times cited : (37)

References (56)
  • 1
    • 17444417521 scopus 로고    scopus 로고
    • Cancer epigenetics
    • 10.1093/hmg/ddi113, 15809275
    • Laird PW. Cancer epigenetics. Hum Mol Genet 2005, 14(Spec No 1):R65-76. 10.1093/hmg/ddi113, 15809275.
    • (2005) Hum Mol Genet , vol.14 , Issue.SPEC NO 1
    • Laird, P.W.1
  • 2
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • 10.1056/NEJMra023075, 14627790
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003, 349(21):2042-2054. 10.1056/NEJMra023075, 14627790.
    • (2003) N Engl J Med , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 3
    • 0037393981 scopus 로고    scopus 로고
    • Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas
    • Komine C, Watanabe T, Katayama Y, Yoshino A, Yokoyama T, Fukushima T. Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas. Brain Pathol 2003, 13(2):176-184.
    • (2003) Brain Pathol , vol.13 , Issue.2 , pp. 176-184
    • Komine, C.1    Watanabe, T.2    Katayama, Y.3    Yoshino, A.4    Yokoyama, T.5    Fukushima, T.6
  • 4
    • 0030823671 scopus 로고    scopus 로고
    • Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene
    • Qian XC, Brent TP. Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene. Cancer Res 1997, 57(17):3672-3677.
    • (1997) Cancer Res , vol.57 , Issue.17 , pp. 3672-3677
    • Qian, X.C.1    Brent, T.P.2
  • 5
    • 0030874380 scopus 로고    scopus 로고
    • Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene
    • 232409, 9271436
    • Watts GS, Pieper RO, Costello JF, Peng YM, Dalton WS, Futscher BW. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Mol Cell Biol 1997, 17(9):5612-5619. 232409, 9271436.
    • (1997) Mol Cell Biol , vol.17 , Issue.9 , pp. 5612-5619
    • Watts, G.S.1    Pieper, R.O.2    Costello, J.F.3    Peng, Y.M.4    Dalton, W.S.5    Futscher, B.W.6
  • 6
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999, 59(4):793-797.
    • (1999) Cancer Res , vol.59 , Issue.4 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 8
    • 0030479125 scopus 로고    scopus 로고
    • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
    • Liu L, Markowitz S, Gerson SL. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res 1996, 56(23):5375-5379.
    • (1996) Cancer Res , vol.56 , Issue.23 , pp. 5375-5379
    • Liu, L.1    Markowitz, S.2    Gerson, S.L.3
  • 9
    • 1942469956 scopus 로고    scopus 로고
    • MGMT: its role in cancer aetiology and cancer therapeutics
    • 10.1038/nrc1319, 15057289
    • Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer 2004, 4(4):296-307. 10.1038/nrc1319, 15057289.
    • (2004) Nat Rev Cancer , vol.4 , Issue.4 , pp. 296-307
    • Gerson, S.L.1
  • 10
    • 0028171276 scopus 로고
    • O6-alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications
    • 10.1007/BF01052897, 7861189
    • Hotta T, Saito Y, Fujita H, Mikami T, Kurisu K, Kiya K, Uozumi T, Isowa G, Ishizaki K, Ikenaga M. O6-alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications. J Neurooncol 1994, 21(2):135-140. 10.1007/BF01052897, 7861189.
    • (1994) J Neurooncol , vol.21 , Issue.2 , pp. 135-140
    • Hotta, T.1    Saito, Y.2    Fujita, H.3    Mikami, T.4    Kurisu, K.5    Kiya, K.6    Uozumi, T.7    Isowa, G.8    Ishizaki, K.9    Ikenaga, M.10
  • 11
    • 13344282752 scopus 로고    scopus 로고
    • Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine
    • Belanich M, Pastor M, Randall T, Guerra D, Kibitel J, Alas L, Li B, Citron M, Wasserman P, White A, et al. Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine. Cancer Res 1996, 56(4):783-788.
    • (1996) Cancer Res , vol.56 , Issue.4 , pp. 783-788
    • Belanich, M.1    Pastor, M.2    Randall, T.3    Guerra, D.4    Kibitel, J.5    Alas, L.6    Li, B.7    Citron, M.8    Wasserman, P.9    White, A.10
  • 12
    • 0031595389 scopus 로고    scopus 로고
    • Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study
    • Jaeckle KA, Eyre HJ, Townsend JJ, Schulman S, Knudson HM, Belanich M, Yarosh DB, Bearman SI, Giroux DJ, Schold SC. Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study. J Clin Oncol 1998, 16(10):3310-3315.
    • (1998) J Clin Oncol , vol.16 , Issue.10 , pp. 3310-3315
    • Jaeckle, K.A.1    Eyre, H.J.2    Townsend, J.J.3    Schulman, S.4    Knudson, H.M.5    Belanich, M.6    Yarosh, D.B.7    Bearman, S.I.8    Giroux, D.J.9    Schold, S.C.10
  • 15
    • 0035853467 scopus 로고    scopus 로고
    • Local DNA demethylation in vertebrates: how could it be performed and targeted?
    • 10.1016/S0014-5793(01)02328-6, 11311228
    • Kress C, Thomassin H, Grange T. Local DNA demethylation in vertebrates: how could it be performed and targeted?. FEBS Lett 2001, 494(3):135-140. 10.1016/S0014-5793(01)02328-6, 11311228.
    • (2001) FEBS Lett , vol.494 , Issue.3 , pp. 135-140
    • Kress, C.1    Thomassin, H.2    Grange, T.3
  • 16
    • 0038732266 scopus 로고    scopus 로고
    • Polymerase chain reaction-based methods of DNA methylation analysis
    • 10.1016/S0003-2697(03)00169-6, 12758266
    • Liu ZJ, Maekawa M. Polymerase chain reaction-based methods of DNA methylation analysis. Anal Biochem 2003, 317(2):259-265. 10.1016/S0003-2697(03)00169-6, 12758266.
    • (2003) Anal Biochem , vol.317 , Issue.2 , pp. 259-265
    • Liu, Z.J.1    Maekawa, M.2
  • 18
    • 0036962761 scopus 로고    scopus 로고
    • Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis
    • 10.1002/elps.200290023, 12481262
    • Uhlmann K, Brinckmann A, Toliat MR, Ritter H, Nurnberg P. Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis 2002, 23(24):4072-4079. 10.1002/elps.200290023, 12481262.
    • (2002) Electrophoresis , vol.23 , Issue.24 , pp. 4072-4079
    • Uhlmann, K.1    Brinckmann, A.2    Toliat, M.R.3    Ritter, H.4    Nurnberg, P.5
  • 19
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Erratum, N Engl J Med 2000;1343: 1740, 10.1056/NEJM200011093431901, 11070098
    • Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, Baylin SB, Herman JG. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000, 343(19):1350-1354. Erratum, N Engl J Med 2000;1343: 1740, 10.1056/NEJM200011093431901, 11070098.
    • (2000) N Engl J Med , vol.343 , Issue.19 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3    Goodman, S.N.4    Hidalgo, O.F.5    Vanaclocha, V.6    Baylin, S.B.7    Herman, J.G.8
  • 20
    • 34548760880 scopus 로고    scopus 로고
    • MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas
    • 10.1038/labinvest.3700664, 17700563
    • Jeuken JW, Cornelissen SJ, Vriezen M, Dekkers MM, Errami A, Sijben A, Boots-Sprenger SH, Wesseling P. MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas. Lab Invest 2007, 87(10):1055-1065. 10.1038/labinvest.3700664, 17700563.
    • (2007) Lab Invest , vol.87 , Issue.10 , pp. 1055-1065
    • Jeuken, J.W.1    Cornelissen, S.J.2    Vriezen, M.3    Dekkers, M.M.4    Errami, A.5    Sijben, A.6    Boots-Sprenger, S.H.7    Wesseling, P.8
  • 21
    • 33947536116 scopus 로고    scopus 로고
    • A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue
    • Cankovic M, Mikkelsen T, Rosenblum ML, Zarbo RJ. A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue. Lab Invest 2007, 87(4):392-397.
    • (2007) Lab Invest , vol.87 , Issue.4 , pp. 392-397
    • Cankovic, M.1    Mikkelsen, T.2    Rosenblum, M.L.3    Zarbo, R.J.4
  • 22
    • 0033397844 scopus 로고    scopus 로고
    • Identification of 5-methylcytosine in complex genomes
    • 10.1006/meth.1999.0883, 10579942
    • Thomassin H, Oakeley EJ, Grange T. Identification of 5-methylcytosine in complex genomes. Methods 1999, 19(3):465-475. 10.1006/meth.1999.0883, 10579942.
    • (1999) Methods , vol.19 , Issue.3 , pp. 465-475
    • Thomassin, H.1    Oakeley, E.J.2    Grange, T.3
  • 23
    • 0036753290 scopus 로고    scopus 로고
    • DNA methylation: a profile of methods and applications
    • Fraga MF, Esteller M. DNA methylation: a profile of methods and applications. Biotechniques 2002, 33(3):636-649.
    • (2002) Biotechniques , vol.33 , Issue.3 , pp. 636-649
    • Fraga, M.F.1    Esteller, M.2
  • 25
    • 41649112995 scopus 로고    scopus 로고
    • Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR
    • 10.1186/1471-2407-8-61, 2266933, 18298842
    • Lorente A, Mueller W, Undargarin E, Lázcoz P, vonDeimling A, Castresana JS. Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR. BMC Cancer 2008, 8:61. 10.1186/1471-2407-8-61, 2266933, 18298842.
    • (2008) BMC Cancer , vol.8 , pp. 61
    • Lorente, A.1    Mueller, W.2    Undargarin, E.3    Lázcoz, P.4    vonDeimling, A.5    Castresana, J.S.6
  • 26
    • 65549117575 scopus 로고    scopus 로고
    • Quantitation of DNA methylation by melt curve analysis
    • 10.1186/1471-2407-9-123, 2679043, 19393074
    • Smith E, Jones ME, Drew PA. Quantitation of DNA methylation by melt curve analysis. BMC Cancer 2009, 9:123. 10.1186/1471-2407-9-123, 2679043, 19393074.
    • (2009) BMC Cancer , vol.9 , pp. 123
    • Smith, E.1    Jones, M.E.2    Drew, P.A.3
  • 27
    • 47649131468 scopus 로고    scopus 로고
    • Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma
    • 10.2353/jmoldx.2008.070169, 2438202, 18556773
    • Vlassenbroeck I, Califice S, Diserens AC, Migliavacca E, Straub J, Di Stefano I, Moreau F, Hamou MF, Renard I, Delorenzi M, et al. Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma. J Mol Diagn 2008, 10(4):332-337. 10.2353/jmoldx.2008.070169, 2438202, 18556773.
    • (2008) J Mol Diagn , vol.10 , Issue.4 , pp. 332-337
    • Vlassenbroeck, I.1    Califice, S.2    Diserens, A.C.3    Migliavacca, E.4    Straub, J.5    Di Stefano, I.6    Moreau, F.7    Hamou, M.F.8    Renard, I.9    Delorenzi, M.10
  • 28
    • 34247849498 scopus 로고    scopus 로고
    • Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation
    • 10.1093/nar/gkm013, 1874596, 17289753
    • Wojdacz TK, Dobrovic A. Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation. Nucleic Acids Res 2007, 35(6):e41. 10.1093/nar/gkm013, 1874596, 17289753.
    • (2007) Nucleic Acids Res , vol.35 , Issue.6
    • Wojdacz, T.K.1    Dobrovic, A.2
  • 29
    • 38749084584 scopus 로고    scopus 로고
    • Locked nucleic acids can enhance the analytical performance of quantitative methylation-specific polymerase chain reaction
    • 10.2353/jmoldx.2008.070076, 2175541, 18165272
    • Gustafson KS. Locked nucleic acids can enhance the analytical performance of quantitative methylation-specific polymerase chain reaction. J Mol Diagn 2008, 10(1):33-42. 10.2353/jmoldx.2008.070076, 2175541, 18165272.
    • (2008) J Mol Diagn , vol.10 , Issue.1 , pp. 33-42
    • Gustafson, K.S.1
  • 32
    • 34347269034 scopus 로고    scopus 로고
    • World Health Organization Classification of Tumours of the Central Nervous System
    • IARC Lyon
    • Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. World Health Organization Classification of Tumours of the Central Nervous System. 2007, IARC Lyon.
    • (2007)
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3    Cavenee, W.K.4
  • 33
    • 33745634349 scopus 로고    scopus 로고
    • Genetic similarities and differences between lobular in situ neoplasia (LN) and invasive lobular carcinoma of the breast
    • 10.1007/s00428-006-0192-7, 16612623
    • Morandi L, Marucci G, Foschini MP, Cattani MG, Pession A, Riva C, Eusebi V. Genetic similarities and differences between lobular in situ neoplasia (LN) and invasive lobular carcinoma of the breast. Virchows Arch 2006, 449(1):14-23. 10.1007/s00428-006-0192-7, 16612623.
    • (2006) Virchows Arch , vol.449 , Issue.1 , pp. 14-23
    • Morandi, L.1    Marucci, G.2    Foschini, M.P.3    Cattani, M.G.4    Pession, A.5    Riva, C.6    Eusebi, V.7
  • 36
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: designing primers for methylation PCRs
    • 10.1093/bioinformatics/18.11.1427, 12424112
    • Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002, 18(11):1427-1431. 10.1093/bioinformatics/18.11.1427, 12424112.
    • (2002) Bioinformatics , vol.18 , Issue.11 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2
  • 37
    • 0038723184 scopus 로고    scopus 로고
    • Enhanced allele-specific PCR discrimination in SNP genotyping using 3' locked nucleic acid (LNA) primers
    • 10.1002/humu.10228, 12815597
    • Latorra D, Campbell K, Wolter A, Hurley JM. Enhanced allele-specific PCR discrimination in SNP genotyping using 3' locked nucleic acid (LNA) primers. Hum Mutat 2003, 22(1):79-85. 10.1002/humu.10228, 12815597.
    • (2003) Hum Mutat , vol.22 , Issue.1 , pp. 79-85
    • Latorra, D.1    Campbell, K.2    Wolter, A.3    Hurley, J.M.4
  • 38
    • 0142042119 scopus 로고    scopus 로고
    • Common technical specification for in vitro diagnostic medical devices
    • Liikanen E. Common technical specification for in vitro diagnostic medical devices. Official Journal of European Community 2002, L131:17-30.
    • (2002) Official Journal of European Community , vol.L131 , pp. 17-30
    • Liikanen, E.1
  • 39
    • 12144291692 scopus 로고    scopus 로고
    • Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
    • 10.1158/1078-0432.CCR-03-0384, 15041700
    • Hegi ME, Diserens AC, Godard S, Dietrich PY, Regli L, Ostermann S, Otten P, VanMelle G, deTribolet N, Stupp R. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 2004, 10(6):1871-1874. 10.1158/1078-0432.CCR-03-0384, 15041700.
    • (2004) Clin Cancer Res , vol.10 , Issue.6 , pp. 1871-1874
    • Hegi, M.E.1    Diserens, A.C.2    Godard, S.3    Dietrich, P.Y.4    Regli, L.5    Ostermann, S.6    Otten, P.7    VanMelle, G.8    deTribolet, N.9    Stupp, R.10
  • 40
    • 37449003812 scopus 로고    scopus 로고
    • Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3
    • 10.1016/S1470-2045(07)70384-4, 18082451
    • Gorlia T, Bent MJ, Hegi ME, Mirimanoff RO, Weller M, Cairncross JG, Eisenhauer E, Belanger K, Brandes AA, Allgeier A, et al. Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3. Lancet Oncol 2008, 9(1):29-38. 10.1016/S1470-2045(07)70384-4, 18082451.
    • (2008) Lancet Oncol , vol.9 , Issue.1 , pp. 29-38
    • Gorlia, T.1    Bent, M.J.2    Hegi, M.E.3    Mirimanoff, R.O.4    Weller, M.5    Cairncross, J.G.6    Eisenhauer, E.7    Belanger, K.8    Brandes, A.A.9    Allgeier, A.10
  • 41
    • 0038002236 scopus 로고    scopus 로고
    • Analysis and quantification of multiple methylation variable positions in CpG islands by Pyrosequencing
    • Tost J, Dunker J, Gut IG. Analysis and quantification of multiple methylation variable positions in CpG islands by Pyrosequencing. Biotechniques 2003, 35(1):152-156.
    • (2003) Biotechniques , vol.35 , Issue.1 , pp. 152-156
    • Tost, J.1    Dunker, J.2    Gut, I.G.3
  • 42
    • 0029843950 scopus 로고    scopus 로고
    • Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
    • 10.1073/pnas.93.18.9821, 38513, 8790415
    • Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996, 93(18):9821-9826. 10.1073/pnas.93.18.9821, 38513, 8790415.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.18 , pp. 9821-9826
    • Herman, J.G.1    Graff, J.R.2    Myohanen, S.3    Nelkin, B.D.4    Baylin, S.B.5
  • 43
    • 16544382188 scopus 로고    scopus 로고
    • MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome
    • 10.1093/nar/gnh166, 535695, 15576675
    • Thomassin H, Kress C, Grange T. MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome. Nucleic Acids Res 2004, 32(21):e168. 10.1093/nar/gnh166, 535695, 15576675.
    • (2004) Nucleic Acids Res , vol.32 , Issue.21
    • Thomassin, H.1    Kress, C.2    Grange, T.3
  • 44
    • 42649109339 scopus 로고    scopus 로고
    • A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis
    • 10.1016/j.ab.2008.03.014, 18384736
    • Hattermann K, Mehdorn HM, Mentlein R, Schultka S, Held-Feindt J. A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis. Anal Biochem 2008, 377(1):62-71. 10.1016/j.ab.2008.03.014, 18384736.
    • (2008) Anal Biochem , vol.377 , Issue.1 , pp. 62-71
    • Hattermann, K.1    Mehdorn, H.M.2    Mentlein, R.3    Schultka, S.4    Held-Feindt, J.5
  • 45
    • 33644835805 scopus 로고    scopus 로고
    • Identification of novel genomic markers related to progression to glioblastoma through genomic profiling of 25 primary glioma cell lines
    • 10.1038/sj.onc.1209177, 16247447
    • Roversi G, Pfundt R, Moroni RF, Magnani I, van Reijmersdal S, Pollo B, Straatman H, Larizza L, Schoenmakers EF. Identification of novel genomic markers related to progression to glioblastoma through genomic profiling of 25 primary glioma cell lines. Oncogene 2006, 25(10):1571-1583. 10.1038/sj.onc.1209177, 16247447.
    • (2006) Oncogene , vol.25 , Issue.10 , pp. 1571-1583
    • Roversi, G.1    Pfundt, R.2    Moroni, R.F.3    Magnani, I.4    van Reijmersdal, S.5    Pollo, B.6    Straatman, H.7    Larizza, L.8    Schoenmakers, E.F.9
  • 46
    • 66349133436 scopus 로고    scopus 로고
    • High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray
    • 10.1158/1541-7786.MCR-08-0270, 19435819
    • Yin D, Ogawa S, Kawamata N, Tunici P, Finocchiaro G, Eoli M, Ruckert C, Huynh T, Liu G, Kato M, et al. High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray. Mol Cancer Res 2009, 7(5):665-677. 10.1158/1541-7786.MCR-08-0270, 19435819.
    • (2009) Mol Cancer Res , vol.7 , Issue.5 , pp. 665-677
    • Yin, D.1    Ogawa, S.2    Kawamata, N.3    Tunici, P.4    Finocchiaro, G.5    Eoli, M.6    Ruckert, C.7    Huynh, T.8    Liu, G.9    Kato, M.10
  • 48
    • 58149204044 scopus 로고    scopus 로고
    • Exploratory analysis of the copy number alterations in glioblastoma multiforme
    • 10.1371/journal.pone.0004076, 2605252, 19115005
    • Freire P, Vilela M, Deus H, Kim YW, Koul D, Colman H, Aldape KD, Bogler O, Yung WK, Coombes K, et al. Exploratory analysis of the copy number alterations in glioblastoma multiforme. PLoS One 2008, 3(12):e4076. 10.1371/journal.pone.0004076, 2605252, 19115005.
    • (2008) PLoS One , vol.3 , Issue.12
    • Freire, P.1    Vilela, M.2    Deus, H.3    Kim, Y.W.4    Koul, D.5    Colman, H.6    Aldape, K.D.7    Bogler, O.8    Yung, W.K.9    Coombes, K.10
  • 49
    • 55249111768 scopus 로고    scopus 로고
    • Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays
    • 10.1186/1471-2164-9-489, 2576260, 18928532
    • Gardina PJ, Lo KC, Lee W, Cowell JK, Turpaz Y. Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays. BMC Genomics 2008, 9:489. 10.1186/1471-2164-9-489, 2576260, 18928532.
    • (2008) BMC Genomics , vol.9 , pp. 489
    • Gardina, P.J.1    Lo, K.C.2    Lee, W.3    Cowell, J.K.4    Turpaz, Y.5
  • 50
    • 38549158349 scopus 로고    scopus 로고
    • Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization
    • 10.1002/gcc.20524, 18050302
    • Lo KC, Bailey D, Burkhardt T, Gardina P, Turpaz Y, Cowell JK. Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization. Genes Chromosomes Cancer 2008, 47(3):221-237. 10.1002/gcc.20524, 18050302.
    • (2008) Genes Chromosomes Cancer , vol.47 , Issue.3 , pp. 221-237
    • Lo, K.C.1    Bailey, D.2    Burkhardt, T.3    Gardina, P.4    Turpaz, Y.5    Cowell, J.K.6
  • 51
    • 70349630234 scopus 로고    scopus 로고
    • Comparative analyses of gene copy number and mRNA expression in GBM tumors and GBM xenografts
    • 10.1215/15228517-2008-113, 19139420
    • Hodgson JG, Yeh RF, Ray A, Wang NJ, Smirnov I, Yu M, Hariono S, Silber J, Feiler HS, Gray JW, et al. Comparative analyses of gene copy number and mRNA expression in GBM tumors and GBM xenografts. Neuro Oncol 2009, 11(5):477-87. 10.1215/15228517-2008-113, 19139420.
    • (2009) Neuro Oncol , vol.11 , Issue.5 , pp. 477-487
    • Hodgson, J.G.1    Yeh, R.F.2    Ray, A.3    Wang, N.J.4    Smirnov, I.5    Yu, M.6    Hariono, S.7    Silber, J.8    Feiler, H.S.9    Gray, J.W.10
  • 52
    • 0027319769 scopus 로고
    • PCR amplification of specific alleles: rapid detection of known mutations and polymorphisms
    • Bottema CD, Sommer SS. PCR amplification of specific alleles: rapid detection of known mutations and polymorphisms. Mutat Res 1993, 288(1):93-102.
    • (1993) Mutat Res , vol.288 , Issue.1 , pp. 93-102
    • Bottema, C.D.1    Sommer, S.S.2
  • 54
    • 33750631751 scopus 로고    scopus 로고
    • Real-time quantitative allele discrimination assay using 3' locked nucleic acid primers for detection of low-percentage mosaic mutations
    • 10.1016/j.ab.2006.07.039, 16962063
    • Maertens O, Legius E, Speleman F, Messiaen L, Vandesompele J. Real-time quantitative allele discrimination assay using 3' locked nucleic acid primers for detection of low-percentage mosaic mutations. Anal Biochem 2006, 359(1):144-146. 10.1016/j.ab.2006.07.039, 16962063.
    • (2006) Anal Biochem , vol.359 , Issue.1 , pp. 144-146
    • Maertens, O.1    Legius, E.2    Speleman, F.3    Messiaen, L.4    Vandesompele, J.5
  • 56
    • 22244448679 scopus 로고    scopus 로고
    • The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
    • 10.1158/0008-5472.CAN-05-0715, 16024643
    • Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res 2005, 65(14):6394-6400. 10.1158/0008-5472.CAN-05-0715, 16024643.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6394-6400
    • Trivedi, R.N.1    Almeida, K.H.2    Fornsaglio, J.L.3    Schamus, S.4    Sobol, R.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.