Corrigendum: Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma (British Journal of Cancer (2015) 113 (902-913) DOI: 10.1038/bjc.2015.255);Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma

British Journal of Cancer

Volumn 113, Issue 6, 2015, Pages 902-913

  Andreev, Katerina ^a   Denis Iulian Trufa, I ^a   Siegemund, Raphaela ^a   Rieker, Ralf ^a   Hartmann, Arndt ^a   Schmidt, Joachim ^a   Sirbu, Horia ^a   Finotto, Susetta ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EOMESODERMIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; MESSENGER RNA; PERFORIN; PHOSPHORYLATED STAT1 ALPHA PROTEIN; PROGRAMMED DEATH 1 LIGAND 1; STAT1 PROTEIN; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CYTOKINE; EOMES PROTEIN, HUMAN; GAMMA INTERFERON ACTIVATION FACTOR; INTERFERON STIMULATED GENE FACTOR 3; ISOPROTEIN; PARAFFIN; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 RECEPTOR; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TUMOR PROTEIN;

ADULT; AGED; ALTERNATIVE RNA SPLICING; APOPTOSIS ASSAY; ARTICLE; CANCER IMMUNOLOGY; CANCER LOCALIZATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL DEATH; CELL ISOLATION; CELLULAR DISTRIBUTION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; MALE; MIDDLE AGED; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; SECRETORY GRANULE; SQUAMOUS CELL LUNG CARCINOMA; SURVIVAL RATE; TH1 CELL; TUMOR MICROENVIRONMENT; UPREGULATION; VERY ELDERLY; WESTERN BLOTTING; YOUNG ADULT; ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; GENETICS; IMMUNOLOGY; LUNG NEOPLASMS; LYMPHOCYTE COUNT; TUMOR ASSOCIATED LEUKOCYTE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; FEMALE; HUMANS; INTERFERON-GAMMA; INTERFERON-STIMULATED GENE FACTOR 3; LUNG NEOPLASMS; LYMPHOCYTE COUNT; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PARAFFIN EMBEDDING; PERFORIN; PROGRAMMED CELL DEATH 1 RECEPTOR; PROTEIN ISOFORMS; RNA, MESSENGER; T-BOX DOMAIN PROTEINS; YOUNG ADULT;

EID: 84941877002     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2016.299     Document Type: Erratum

References (31)

1. Afkarian M, Sedy JR, Yang J, Jacobson NG, Cereb N, Yang SY, Murphy TL, Murphy KM (2002) T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4 T cells. Nat Immunol 3(6): 549-557.
2. Balabko L, Andreev K, Burmann N, Schubert M, Mathews M, Trufa DI, Reppert S, Rau T, Schicht M, Sirbu H, Hartmann A, Finotto S (2014) Increased expression of the Th17-IL-6R/pSTAT3/BATF/Rorgamma T-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung. Sci Rep 4: 7396.
3. Byrne WL, Mills KH, Lederer JA, O'Sullivan GC (2011) Targeting regulatory T cells in cancer. Cancer Res 71(22): 6915-6920.
4. Chon SY, Hassanain HH, Gupta SL (1996) Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferongamma-inducible expression of human indoleamine 2, 3-dioxygenase gene. J Biol Chem 271(29): 17247-17252.
5. Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A (2009) Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J Exp Med 206(1): 51-59.
6. Domagala-Kulawik J (2015) The role of the immune system in non-small cell lung carcinoma and potential for therapeutic intervention. Transl Lung Cancer Res 4(2): 177-190.
7. Greenlee RT, Hill-Harmon MB, Murray T, Thun M (2001) Cancer statistics, 2001. CA Cancer J Clin 51(1): 15-36.
8. Herbst RS, Heymach JV, Lippman SM (2008) Lung cancer. N Engl J Med 359(13): 1367-1380.
9. Hodge G, Barnawi J, Jurisevic C, Moffat D, Holmes M, Reynolds PN, Jersmann H, Hodge S (2014) Lung cancer is associated with decreased expression of perforin, granzyme B and interferon (IFN)-gamma by infiltrating lung tissue T cells, natural killer (NK) T-like and N Clin Exp Immunol 178(1): 79-85.
10. Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, Goldrath AW, Ahmed R, Reiner SL (2005) Effector and memory CD8 T cell fate coupled by T-bet and eomesodermin. Nat Immunol 6(12): 1236-1244.
11. Jager E, Gnjatic S, Nagata Y, Stockert E, Jager D, Karbach J, Neumann A, Rieckenberg J, Chen YT, Ritter G, Hoffman E, Arand M, Old LJ, Knuth A (2000) Induction of primary NY-ESO-1 immunity: CD8 T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1 cancers. Proc Natl Acad Sci USA 97(22): 12198-12203.
12. Jeon HS, Jen J (2010) TGF-beta signaling and the role of inhibitory Smads in non-small cell lung cancer. J Thorac Oncol 5(4): 417-419.
13. Keir ME, Butte MJ, Freeman GJ, Sharpe AH (2008) PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 26: 677-704.
14. Kimura N, Nakashima K, Ueno M, Kiyama H, Taga T (1999) A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain. Brain Res Dev Brain Res 115(2): 183-193.
15. Ladoire S, Arnould L, Mignot G, Apetoh L, Rébé C, Martin F, Fumoleau P, Coudert B, Ghiringhelli F (2011) T-bet expression in intratumoral lymphoid structures after neoadjuvant trastuzumab plus docetaxel for HER2-overexpressing breast carcinoma predicts survival. Br J Cancer 105(3): 366-371.
16. Lazarevic V, Glimcher LH, Lord GM (2013) T-bet: a bridge between innate and adaptive immunity. Nat Rev Immunol 13(11): 777-789.
17. Leonard JP, Sherman ML, Fisher GL, Buchanan LJ, Larsen G, Atkins MB, Sosman JA, Dutcher JP, Vogelzang NJ, Ryan JL (1997) Effects of singledose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood 90(7): 2541-2548.
18. Li J, Jie HB, Lei Y, Gildener-Leapman N, Trivedi S, Green T, Kane LP, Ferris RL (2015) PD-1/SHP-2 inhibits Tc1/Th1 phenotypic responses and the activation of T cells in the tumor microenvironment. Cancer Res 75(3): 508-518.
19. Lighvani AA, Frucht DM, Jankovic D, Yamane H, Aliberti J, Hissong BD, Nguyen BV, Gadina M, Sher A, Paul WE, O'Shea JJ (2001) T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc Natl Acad Sci USA 98(26): 15137-15142.
20. Metkar SS, Wang B, Aguilar-Santelises M, Raja SM, Uhlin-Hansen L, Podack E, Trapani JA, Froelich CJ (2002) Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation. Immunity 16(3): 417-428.
21. Mocellin S, Marincola FM, Young HA (2005) Interleukin-10 and the immune response against cancer: a counterpoint. J Leukoc Biol 78(5): 1043-1051.
22. Muller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell Jr JE, Stark GR, Kerr IM (1993) Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and-gamma signal transduction pathways. EMBO J 12(11): 4221-4228.
23. Najjar I, Schischmanoff PO, Baran-Marszak F, Deglesne PA, Youlyouz-Marfak I, Pampin M, Feuillard J, Bornkamm GW, Chelbi-Alix MK, Fagard R (2008) Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha. J Leukoc Biol 84(6): 1604-1612.
24. Pestka S, Krause CD, Walter MR (2004) Interferons, interferon-like cytokines, and their receptors. Immunol Rev 202: 8-32.
25. Reppert S, Boross I, Koslowski M, Tureci O, Koch S, Lehr HA, Finotto S (2011) A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer. Nat Commun 2: 600.
26. Schindler C, Fu XY, Improta T, Aebersold R, Darnell Jr JE (1992) Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci USA 89(16): 7836-7839.
27. Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100(6): 655-669.
28. Trapani JA, Smyth MJ (2002) Functional significance of the perforin/ granzyme cell death pathway. Nat Rev Immunol 2(10): 735-747.
29. Travis WD, Travis LB, Devesa SS (1995) Lung cancer. Cancer 75(1 Suppl): 191-202.
30. Van Overmeire E, Laoui D, Keirsse J, Bonelli S, Lahmar Q, Van Ginderachter JA (2014) STAT of the union: dynamics of distinct tumor-associated macrophage subsets governed by STAT1. Eur J Immunol 44(8): 2238-2242.
31. Yu H, Yang J, Jiao S, Li Y, Zhang W, Wang J (2014) T-box transcription factor 21 expression in breast cancer and its relationship with prognosis. Int J Clin Exp Pathol 7(10): 6906-6913.