Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorγT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung
Results of the two incidence screenings in the National Lung Screening Trial
Aberle, D. R. et al. Results of the two incidence screenings in the National Lung Screening Trial. N Engl J Med 369, 920-931, doi:10.1056/NEJMoa1208962 (2013).
KRAS mutations in non-small-cell lung cancer and colorectal cancer: Implications for EGFR-targeted therapies
Maus, M. K. et al. KRAS mutations in non-small-cell lung cancer and colorectal cancer: Implications for EGFR-targeted therapies. Lung cancer, doi: 10.1016/j.lungcan.2013.11.010 (2013).
Comparison of clinical characteristics between patients with ALK-positive and EGFR-positive lung adenocarcinoma
Kang, H. J. et al. Comparison of clinical characteristics between patients with ALK-positive and EGFR-positive lung adenocarcinoma. Respir Med, doi:10.1016/j.rmed.2013.11.020 (2013).
JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling
Song, L., Rawal, B., Nemeth, J. A. & Haura, E. B. JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling. MCT 10, 481-494, doi:10.1158/1535-7163. MCT-10-0502 (2011).
Therapeutical measures to control airway tolerance in asthma and lung cancer
Andreev, K., Graser, A., Maier, A., Mousset, S. & Finotto, S. Therapeutical measures to control airway tolerance in asthma and lung cancer. Front Immunol 3, 216, doi:10.3389/fimmu.2012.00216 (2012).
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A. & Sallusto, F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 8, 942-949, doi:10.1038/ni1496 (2007).
Loss of STAT3 in CD41 T cells prevents development of experimental autoimmune diseases
Liu, X., Lee, Y. S., Yu, C. R. & Egwuagu, C. E. Loss of STAT3 in CD41 T cells prevents development of experimental autoimmune diseases. J Immunol 180, 6070-6076 (2008).
Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
Hirahara, K. et al. Signal transduction pathways and transcriptional regulation in Th17 cell differentiation. Cytokine Growth Factor Rev 21, 425-434, doi:10.1016/j.cytogfr.2010.10.006 (2010).
Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells
Liao, J., Humphrey, S. E., Poston, S. & Taparowsky, E. J. Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells. MCR 9, 350-363, doi:10.1158/1541-7786. MCR-10-0375 (2011).
STATs in cancer inflammation and immunity: A leading role for STAT3
Yu, H., Pardoll, D. & Jove, R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 9, 798-809, doi:10.1038/nrc2734 (2009).
IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy
Koch, S. et al. IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy. SciRep 3, 1754, doi:10.1038/srep01754 (2013).
The IL-6R alpha chain controls lung CD41CD251 Treg development and function during allergic airway inflammation in vivo
Doganci, A. et al. The IL-6R alpha chain controls lung CD41CD251 Treg development and function during allergic airway inflammation in vivo. J Clin Invest 115, 313-325, doi:10.1172/JCI22433 (2005).
The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast celldriven immune responses in the setting of allergic asthma
e191-199
Ubel, C. et al. The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast celldriven immune responses in the setting of allergic asthma. J Allergy Clin Immunol 133, 198-206 e191-199, doi:10.1016/j.jaci.2013.09.049 (2014).
Interleukin-2 receptor signaling in regulatory T cell development and homeostasis
Burchill, M. A., Yang, J., Vang, K. B. & Farrar, M. A. Interleukin-2 receptor signaling in regulatory T cell development and homeostasis. Immunol Lett 114, 1-8, doi:10.1016/j.imlet.2007.08.005 (2007).
Isolation of CD41 T cells from murine lungs: A method to analyze ongoing immune responses in the lung
Sauer, K. A., Scholtes, P., Karwot, R. & Finotto, S. Isolation of CD41 T cells from murine lungs: a method to analyze ongoing immune responses in the lung. Nat Protoc 1, 2870-2875, doi:10.1038/nprot.2006.435 (2006).