Prognostic value of circulating tumor cells with podoplanin expression in patients with locally advanced or metastatic head and neck squamous cell carcinoma

Head and Neck

Volumn 37, Issue 10, 2015, Pages 1448-1455

  Hsieh, Jason Chia Hsun ^a,b   Lin, Hung Chih ^c   Huang, Chi Ya ^c   Hsu, Hsung Ling ^c   Wu, Tyler Min Hsien ^b   Lee, Chia Lin ^d,e   Chen, Min Chi ^c   Wang, Hung Ming ^a,c   Tseng, Ching Ping ^b,c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

and biomarker; circulating tumor cells; head and neck squamous cell carcinoma; podoplanin; prognosis

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE; PODOPLANIN; MEMBRANE PROTEIN; PDPN PROTEIN, HUMAN; TUMOR MARKER;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CELL SUSPENSION; CIRCULATING TUMOR CELL; COHORT ANALYSIS; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; FOLLOW UP; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; FLUORESCENT ANTIBODY TECHNIQUE; HEAD AND NECK TUMOR; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; POLYMERASE CHAIN REACTION; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TUMOR EMBOLISM; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; CARCINOMA, SQUAMOUS CELL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NEOPLASTIC CELLS, CIRCULATING; POLYMERASE CHAIN REACTION; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84941740344     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.23779     Document Type: Article

References (37)

1. Möckelmann N, Laban S, Pantel K, Knecht R,. Circulating tumor cells in head and neck cancer: clinical impact in diagnosis and follow-up. Eur Arch Otorhinolaryngol 2014; 271: 15-21.
2. Datema FR, Ferrier MB, Vergouwe Y, et al., Update and external validation of a head and neck cancer prognostic model. Head Neck 2013; 35: 1232-1237.
3. Ebrahimi A, Clark JR, Ahmadi N, Palme CE, Morgan GJ, Veness MJ,. Prognostic significance of disease-free interval in head and neck cutaneous squamous cell carcinoma with nodal metastases. Head Neck 2013; 35: 1138-1143.
4. Zang J, Li C, Zhao LN, et al., Prognostic value of vascular endothelial growth factor in patients with head and neck cancer: a meta-analysis. Head Neck 2013; 35: 1507-1514.
5. Wheeler S, Siwak DR, Chai R, et al., Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. Clin Cancer Res 2012; 18: 2278-2289.
6. Snietura M, Jaworska M, Mlynarczyk-Liszka J, et al., PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck. PLoS One 2012; 7: e33396.
7. Querellou S, Abgral R, Le Roux PY, et al., Prognostic value of fluorine-18 fluorodeoxyglucose positron-emission tomography imaging in patients with head and neck squamous cell carcinoma. Head Neck 2012; 34: 462-468.
8. Meyer F, Samson E, Douville P, Duchesne T, Liu G, Bairati I,. Serum prognostic markers in head and neck cancer. Clin Cancer Res 2010; 16: 1008-1015.
9. Rettori MM, de Carvalho AC, Bomfim Longo AL, et al., Prognostic significance of TIMP3 hypermethylation in post-treatment salivary rinse from head and neck squamous cell carcinoma patients. Carcinogenesis 2013; 34: 20-27.
10. Cristofanilli M, Budd GT, Ellis MJ, et al., Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 2004; 351: 781-791.
11. Nagrath S, Sequist LV, Maheswaran S, et al., Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 2007; 450: 1235-1239.
12. Jatana KR, Lang JC, Chalmers JJ,. Identification of circulating tumor cells: a prognostic marker in squamous cell carcinoma of the head and neck? Future Oncol 2011;7: 481-484.
13. Nichols AC, Lowes LE, Szeto CC, et al., Detection of circulating tumor cells in advanced head and neck cancer using the CellSearch system. Head Neck 2012; 34: 1440-1444.
14. Hristozova T, Konschak R, Budach V, Tinhofer I,. A simple multicolor flow cytometry protocol for detection and molecular characterization of circulating tumor cells in epithelial cancers. Cytometry A 2012; 81: 489-495.
15. Buglione M, Grisanti S, Almici C, et al., Circulating tumour cells in locally advanced head and neck cancer: preliminary report about their possible role in predicting response to non-surgical treatment and survival. Eur J Cancer 2012; 48: 3019-3026.
16. Tinhofer I, Hristozova T, Stromberger C, Keilhoiz U, Budach V,. Monitoring of circulating tumor cells and their expression of EGFR/phospho-EGFR during combined radiotherapy regimens in locally advanced squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 2012; 83: e685-e690.
17. Aktas B, Tewes M, Fehm T, Hauch S, Kimmig R, Kasimir-Bauer S,. Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res 2009; 11: R46.
18. Balasubramanian P, Lang JC, Jatana KR, et al., Multiparameter analysis, including EMT markers, on negatively enriched blood samples from patients with squamous cell carcinoma of the head and neck. PLoS One 2012; 7: e42048.
19. Martín-Villar E, Scholl FG, Gamallo C, et al., Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas. Int J Cancer 2005; 113: 899-910.
20. Raica M, Cimpean AM, Ribatti D,. The role of podoplanin in tumor progression and metastasis. Anticancer Res 2008; 28: 2997-3006.
21. Kreppel M, Krakowezki A, Kreppel B, et al., Podoplanin expression in cutaneous head and neck squamous cell carcinoma-prognostic value and clinicopathologic implications. J Surg Oncol 2013; 107: 376-383.
22. Vormittag L, Thurnher D, Geleff S, et al., Co-expression of Bmi-1 and podoplanin predicts overall survival in patients with squamous cell carcinoma of the head and neck treated with radio(chemo)therapy. Int J Radiat Oncol Biol Phys 2009; 73: 913-918.
23. McShane LM, Altman DG, Sauerbrei W, et al., Reporting recommendations for tumour marker prognostic studies (REMARK). Br J Cancer 2005; 93: 387-391.
24. Lin HC, Hsu HC, Hsieh CH, et al., A negative selection system PowerMag for effective leukocyte depletion and enhanced detection of EpCAM positive and negative circulating tumor cells. Clin Chim Acta 2013; 419: 77-84.
25. Citri A, Pang ZP, Südhof TC, Wernig M, Malenka RC,. Comprehensive qPCR profiling of gene expression in single neuronal cells. Nat Protoc 2012; 7: 118-127.
26. Strati A, Markou A, Parisi C, et al., Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR. BMC Cancer 2011; 11: 422.
27. Kreppel M, Drebber U, Wedemeyer I, et al., Podoplanin expression predicts prognosis in patients with oral squamous cell carcinoma treated with neoadjuvant radiochemotherapy. Oral Oncol 2011; 47: 873-878.
28. Yuan P, Temam S, El-Naggar A, et al., Overexpression of podoplanin in oral cancer and its association with poor clinical outcome. Cancer 2006; 107: 563-569.
29. Jatana KR, Balasubramanian P, Lang JC, et al., Significance of circulating tumor cells in patients with squamous cell carcinoma of the head and neck: initial results. Arch Otolaryngol Head Neck Surg 2010; 136: 1274-1279.
30. van de Stolpe A, Pantel K, Sleijfer S, Terstappen LW, den Toonder JM,. Circulating tumor cell isolation and diagnostics: toward routine clinical use. Cancer Res 2011; 71: 5955-5960.
31. Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G,. Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 2006; 9: 261-272.
32. Yu M, Bardia A, Wittner BS, et al., Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 2013; 339: 580-584.
33. King TC,. Elsevier's Integrated Pathology. Philadelphia, PA: Mosby Inc.; 2007. pp 111-143.
34. Foschini MP, Leonardi E, Eusebi LH, et al., Podoplanin and E-cadherin expression in preoperative incisional biopsies of oral squamous cell carcinoma is related to lymph node metastases. Int J Surg Pathol 2013; 21: 133-141.
35. Giannelli G, Marinosci F, Sgarra C, Lupo L, Dentico P, Antonaci S,. Clinical role of tissue and serum levels of SCCA antigen in hepatocellular carcinoma. Int J Cancer 2005; 116: 579-583.
36. Zhao YJ, Ju Q, Li GC,. Tumor markers for hepatocellular carcinoma. Mol Clin Oncol 2013; 1: 593-598.
37. Liao CT, Lee LY, Huang SF, et al., Outcome analysis of patients with oral cavity cancer and extracapsular spread in neck lymph nodes. Int J Radiat Oncol Biol Phys 2011; 81: 930-937.