Mechanosensitive activation of CFTR by increased cell volume and hydrostatic pressure but not shear stress

Biochimica et Biophysica Acta - Biomembranes

Volumn 1848, Issue 11, 2015, Pages 2942-2951

  Vitzthum, Constanze ^a   Clauss, Wolfgang G ^a   Fronius, Martin ^b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Cell volume stretch shear stress; Cystic fibrosis transmembrane conductance regulator; Mechanosensitive; Mechanotransduction

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORSKOLIN; CHLORIDE; GLYCINE; HYDRAZINE DERIVATIVE; ISOBUTYLMETHYLXANTHINE; N-(2-NAPHTHALENYL)-((3,5-DIBROMO-2,4-DIHYDROXYPHENYL)METHYLENE)GLYCINE HYDRAZIDE;

ADULT; ARTICLE; CELL ASSAY; CELL VOLUME; CONTROLLED STUDY; FEMALE; HYDROSTATIC PRESSURE; IN VITRO STUDY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEAR STRESS; XENOPUS; ANALOGS AND DERIVATIVES; ANIMAL; CELL SIZE; CHANNEL GATING; CYTOLOGY; DRUG EFFECTS; EPITHELIUM; GENETICS; HUMAN; LUNG; MECHANICAL STRESS; MEMBRANE POTENTIAL; METABOLISM; MUTATION; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; SHEAR STRENGTH; XENOPUS LAEVIS;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CELL SIZE; CHLORIDES; COLFORSIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIUM; FEMALE; GLYCINE; HUMANS; HYDRAZINES; HYDROSTATIC PRESSURE; ION CHANNEL GATING; LUNG; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; SHEAR STRENGTH; STRESS, MECHANICAL; XENOPUS LAEVIS;

EID: 84941703284     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2015.09.009     Document Type: Article

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