Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Nature Communications

Volumn 6, Issue , 2015, Pages

  Huang, Jie ^a   Howie, Bryan ^b   McCarthy, Shane ^a   Memari, Yasin ^a   Walter, Klaudia ^a   Min, Josine L ^c   Danecek, Petr ^a   Malerba, Giovanni ^d   Trabetti, Elisabetta ^d   Zheng, Hou Feng ^e,f   Gambaro, Giovanni ^g   Richards, J Brent ^e,f,h   Durbin, Richard ^a   Timpson, Nicholas J ^c   Marchini, Jonathan ^i,j   Soranzo, Nicole ^a,k   Al Turki, Saeed ^a,l   Amuzu, Antoinette ^m   Anderson, Carl A ^a   Anney, Richard ⁿ   Antony, Dinu ^o   Artigas, María Soler ^p   Ayub, Muhammad ^q   Bala, Senduran ^a   Barrett, Jeffrey C ^a   Barroso, Inês ^a,k   Beales, Phil ^o   Benn, Marianne ^r,s   Bentham, Jamie ^j   Bhattacharya, Shoumo ^j   Birney, Ewan ^a   Blackwood, Douglas ^t   Bobrow, Martin ^u   Bochukova, Elena ^k   Bolton, Patrick F ^h,v,w   Bounds, Rebecca ^k   Boustred, Chris ^x   Breen, Gerome ^v,w   Calissano, Mattia ^x   Carss, Keren ^a   Casas, Juan Pablo ^m,y   Chambers, John C ^z   Charlton, Ruth ^aa   Chatterjee, Krishna ^k   Chen, Lu ^a,k   Ciampi, Antonio ^f   Cirak, Sebahattin ^x,ab   Clapham, Peter ^a   Clement, Gail ^h   Coates, Guy ^a   Cocca, Massimiliano ^ac   Collier, David A ^w,ad   Cosgrove, Catherine ^j   Cox, Tony ^a   Craddock, Nick ^ae   Crooks, Lucy ^a,af   Curran, Sarah ^h,ag,ah   Curtis, David ^y   Daly, Allan ^a   Day, Ian N M ^c   Day Williams, Aaron ^a,ai   Dedoussis, George ^aj   Down, Thomas ^a,ak   Du, Yuanping ^al   Van Duijn, Cornelia M ^am   Dunham, Ian ^a   Edkins, Sarah ^a   Ekong, Rosemary ^y   Ellis, Peter ^a   Evans, David M ^c,an   Farooqi, I Sadaf ^k   Fitzpatrick, David R ^ao   Flicek, Paul ^a   Floyd, James ^a,ap   Foley, A Reghan ^x   Franklin, Christopher S ^a   Futema, Marta ^y   Gallagher, Louise ⁿ   Gasparini, Paolo ^ac,aq   Gaunt, Tom R ^c   Geihs, Matthias ^a   Geschwind, Daniel ^ar   Greenwood, Celia ^e,f   Griffin, Heather ^as   Grozeva, Detelina ^u   Guo, Xiaosen ^al,at   Guo, Xueqin ^al   Gurling, Hugh ^y   Hart, Deborah ^h   Hendricks, Audrey E ^a,au   Holmans, Peter ^ae   Huang, Liren ^al   Hubbard, Tim ^a,ak   Humphries, Steve E ^y   Hurles, Matthew E ^a   Hysi, Pirro ^h   Iotchkova, Valentina ^a   Isaacs, Aaron ^am   Jackson, David K ^a   Jamshidi, Yalda ^av   Johnson, Jon ^aw   Joyce, Chris ^a   Karczewski, Konrad J ^ax,ay   Kaye, Jane ^as   Keane, Thomas ^a   Kemp, John P ^c,an   Kennedy, Karen ^a,az   Kent, Alastair ^ba   Keogh, Julia ^k   Khawaja, Farrah ^av   Kleber, Marcus E ^bb   Van Kogelenberg, Margriet ^a   Kolb Kokocinski, Anja ^a   Kooner, Jaspal S ^bc   Lachance, Genevieve ^h   Langenberg, Claudia ^bd   Langford, Cordelia ^a   Lawson, Daniel ^c   Lee, Irene ^o   Van Leeuwen, Elisabeth M ^am   Lek, Monkol ^ax   Li, Rui ^e,f   Li, Yingrui ^al   Liang, Jieqin ^al   Lin, Hong ^al   Liu, Ryan ^be   Lönnqvist, Jouko ^bf   Lopes, Luis R ^y,bg   Lopes, Margarida ^a,j,bh   Luan, Jian'an ^bd   MacArthur, Daniel G ^ax,ay   Mangino, Massimo ^h,bi   Marenne, Gaëlle ^a   März, Winfried ^bj,bk,bl   Maslen, John ^a   Matchan, Angela ^a   Mathieson, Iain ^bm   McGuffin, Peter ^w   McIntosh, Andrew M ^t   McKechanie, Andrew G ^t,bn   McQuillin, Andrew ^y   Metrustry, Sarah ^h   Migone, Nicola ^bo   Mitchison, Hannah M ^o   Moayyeri, Alireza ^h,y   Morris, James ^a   Morris, Richard ^bp   Muddyman, Dawn ^a   Muntoni, Francesco ^x   Nordestgaard, Børge G ^r,s   Northstone, Kate ^c   O'Donovan, Michael C ^ae   O'Rahilly, Stephen ^k   Onoufriadis, Alexandros ^ak   Oualkacha, Karim ^bq   Owen, Michael J ^ae   Palotie, Aarno ^a,ay,br   Panoutsopoulou, Kalliope ^a   Parker, Victoria ^k   Parr, Jeremy R ^bs   Paternoster, Lavinia ^c   Paunio, Tiina ^bf,br   Payne, Felicity ^a   Payne, Stewart J ^bt   Perry, John R B ^h,bd   Pietilainen, Olli ^a,bf,br   Plagnol, Vincent ^y   Pollitt, Rebecca C ^af   Povey, Sue ^y   Quail, Michael A ^a   Quaye, Lydia ^h   Raymond, Lucy ^u   Rehnström, Karola ^a   Ridout, Cheryl K ^ak   Ring, Susan ^c   Ritchie, Graham R S ^a   Roberts, Nicola ^u   Robinson, Rachel L ^aa   Savage, David B ^k   Scambler, Peter ^o   Schiffels, Stephan ^a   Schmidts, Miriam ^o,bu   Schoenmakers, Nadia ^k   Scott, Richard H ^o,x   Scott, Robert A ^bd   Semple, Robert K ^k   Serra, Eva ^a   Sharp, Sally I ^y   Shaw, Adam ^bi   Shihab, Hashem A ^c   Shin, So Youn ^a,c   Skuse, David ^o   Small, Kerrin S ^h   Smee, Carol ^a   Smith, George Davey ^c   Southam, Lorraine ^a,j   Spasic Boskovic, Olivera ^u   Spector, Timothy D ^h   St Clair, David ^bv   St Pourcain, Beate ^c   Stalker, Jim ^a   Stevens, Elizabeth ^x   Sun, Jianping ^e,f   Surdulescu, Gabriela ^h   Suvisaari, Jaana ^bf   Syrris, Petros ^y   Tachmazidou, Ioanna ^a   Taylor, Rohan ^av   Tian, Jing ^al   Tobin, Martin D ^p,bw   Toniolo, Daniela ^bx   Traglia, Michela ^bx   Tybjaerg Hansen, Anne ^s,by   Valdes, Ana M ^h   Vandersteen, Anthony M ^bz   Varbo, Anette ^r,s   Vijayarangakannan, Parthiban ^a   Visscher, Peter M ^an   Wain, Louise V ^p   Walters, James T R ^ae   Wang, Guangbiao ^al   Wang, Jun ^{al,at,ca,cb,cc}   Wang, Yu ^al   Ward, Kirsten ^h   Wheeler, Eleanor ^a   Whincup, Peter ^av   Whyte, Tamieka ^x   Williams, Hywel J ^o,ae   Williamson, Kathleen A ^ao   Wilson, Crispian ^u   Wilson, Scott G ^h,cd,ce   Wong, Kim ^a   Xu, ChangJiang ^e,f   Yang, Jian ^an   Zaza, Gianluigi ^cf   Zeggini, Eleftheria ^a   Zhang, Feng ^h   Zhang, Pingbo ^al   Zhang, Weihua ^z   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b ADAPTIVE BIOTECHNOLOGIES   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF VERONA   (Italy)

^e MCGILL UNIVERSITY   (Canada)

^f MCGILL UNIVERSITY   (Canada)

^g FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^h KING'S COLLEGE LONDON   (United Kingdom)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

^j UNIVERSITY OF OXFORD   (United Kingdom)

^k UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^l KING SAUD BIN ABDULAZIZ UNIVERSITY FOR HEALTH SCIENCES   (Saudi Arabia)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ ST JAMES S HOSPITAL   (Ireland)

^o UNIVERSITY COLLEGE LONDON   (United Kingdom)

^p UNIVERSITY OF LEICESTER   (United Kingdom)

^q QUEEN S UNIVERSITY   (Canada)

^r GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^s UNIVERSITY OF COPENHAGEN   (Denmark)

^t UNIVERSITY OF EDINBURGH   (United Kingdom)

^u UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^v NATIONAL HEALTH SERVICE   (United Kingdom)

^w MEDICAL RESEARCH COUNCIL   (United Kingdom)

^x GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^y UNIVERSITY COLLEGE LONDON   (United Kingdom)

^z IMPERIAL COLLEGE LONDON   (United Kingdom)

^aa ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^ab UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^ac UNIVERSITY OF TRIESTE   (Italy)

^ad ELI LILLY AND COMPANY   (United States)

^ae CARDIFF UNIVERSITY   (United Kingdom)

^af SHEFFIELD CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

^ag UNIVERSITY OF SUSSEX   (United Kingdom)

^ah SUSSEX PARTNERSHIP NHS FOUNDATION TRUST   (United Kingdom)

^ai BIOGEN   (United States)

^aj HAROKOPIO UNIVERSITY   (Greece)

^ak GUY S HOSPITAL   (United Kingdom)

^al BGI SHENZHEN   (China)

^am ERASMUS MEDICAL CENTER   (Netherlands)

^an UNIVERSITY OF QUEENSLAND   (Australia)

^ao UNIVERSITY OF EDINBURGH   (United Kingdom)

^ap QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^aq Experimental Genetics Division   (Qatar)

^ar UNIVERSITY OF CALIFORNIA   (United States)

^as UNIVERSITY OF OXFORD   (United Kingdom)

^at UNIVERSITY OF COPENHAGEN   (Denmark)

^au UNIVERSITY OF COLORADO   (United States)

^av ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^aw UNIVERSITY OF LONDON   (United Kingdom)

^ax MASSACHUSETTS GENERAL HOSPITAL   (United States)

^ay BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^az INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^ba GENETIC ALLIANCE UK   (United Kingdom)

^bb UNIVERSITY OF HEIDELBERG   (Germany)

^bc NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^bd UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^be BGI Europe   (United Kingdom)

^bf NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^bg UNIVERSITY OF LISBON   (Portugal)

^bh ILLUMINA INC   (United States)

^bi GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^bj MEDICAL UNIVERSITY OF GRAZ   (Austria)

^bk SYNLAB ACADEMY   (Germany)

^bl UNIVERSITY OF HEIDELBERG   (Germany)

^bm HARVARD MEDICAL SCHOOL   (United States)

^bn UNIVERSITY OF EDINBURGH   (United Kingdom)

^bo UNIVERSITY OF TURIN   (Italy)

^bp University of Bristol Canynge Hall   (United Kingdom)

^bq UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^br UNIVERSITY OF HELSINKI   (Finland)

^bs NEWCASTLE UNIVERSITY   (United Kingdom)

^bt NORTHWICK PARK HOSPITAL   (United Kingdom)

^bu RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^bv UNIVERSITY OF ABERDEEN   (United Kingdom)

^bw GLENFIELD HOSPITAL   (United Kingdom)

^bx SAN RAFFAELE HOSPITAL   (Italy)

^by Rigshospitalet   (Denmark)

^bz IWK Grace Health Center   (Canada)

^ca KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^cb MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

^cc UNIVERSITY OF HONG KONG   (Hong Kong)

^cd UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^ce SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^cf UNIVERSITY OF VERONA   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY ASSESSMENT; DATA SET; GENE EXPRESSION; GENETIC VARIATION; GENOME; GENOTYPE;

ACCURACY; ARTICLE; AUTOSOME; CHROMOSOME 20; COHORT ANALYSIS; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HUMAN; INDEL MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM; X CHROMOSOME; Y CHROMOSOME; ADOLESCENT; ADULT; AGED; ALLELE; BIOLOGICAL MODEL; CAUCASIAN; GENETIC VARIATION; GENETICS; HUMAN GENOME; ITALY; MIDDLE AGED; STATISTICAL MODEL; TWINS; UNITED KINGDOM; VERY ELDERLY; YOUNG ADULT;

ITALY; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC VARIATION; GENOME, HUMAN; GENOTYPE; HAPLOTYPES; HUMANS; ITALY; MIDDLE AGED; MODELS, GENETIC; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; UNITED KINGDOM; YOUNG ADULT;

EID: 84941702459     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9111     Document Type: Article

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