A pilot study of conically graded chitosan-gelatin hydrogel/PLGA scaffold with dual-delivery of TGF-β1 and BMP-2 for regeneration of cartilage-bone interface

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 103, Issue 7, 2015, Pages 1344-1353

  Han, Fengxuan ^a   Zhou, Fang ^a   Yang, Xiaoling ^a   Zhao, Jin ^a   Zhao, Yunhui ^a   Yuan, Xiaoyan ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

bone morphogenetic protein 2; cartilage bone interface tissue; hydrogel; poly(l lactide co glycolide); transforming growth factor 1

Indexed keywords

BONE; CARTILAGE; CELL CULTURE; CHITOSAN; COLLAGEN; HYDROGELS; REPAIR; STEM CELLS; TISSUE;

BONE MARROW MESENCHYMAL STEM CELLS; BONE MORPHOGENETIC PROTEIN-2; GLYCOLIDE; GROWTH FACTOR DELIVERY; IN-VIVO EXPERIMENTS; INTERFACE RECONSTRUCTION; OSTEOGENIC DIFFERENTIATION; TRANSFORMING GROWTH FACTORS;

SCAFFOLDS (BIOLOGY);

CHITOSAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; EOSIN; GELATIN; HEMATOXYLIN; OSTEOCALCIN; POLYGLACTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; BMP2 PROTEIN, RAT; BONE MORPHOGENETIC PROTEIN 2; HYDROGEL; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MARROW DERIVED MESENCHYMAL STEM CELL; BONE REGENERATION; BONE TISSUE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HEMATOXYLIN AND EOSIN STAINING; HYALINE CARTILAGE; HYDROGEL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROENCAPSULATION; NONHUMAN; PILOT STUDY; RAT; SPATIOTEMPORAL ANALYSIS; STAINING; SUBCHONDRAL BONE; SURFACE PROPERTY; TISSUE ENGINEERING; ANIMAL; CARTILAGE; CHEMISTRY; DRUG EFFECTS; KNEE INJURIES; METABOLISM; MORTALITY; PATHOLOGY; PHARMACOLOGY; PROCEDURES; RABBIT;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CARTILAGE; DRUG DELIVERY SYSTEMS; GELATIN; HYDROGELS; KNEE INJURIES; LACTIC ACID; PILOT PROJECTS; POLYGLYCOLIC ACID; RABBITS; RATS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84941620274     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.33314     Document Type: Article

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