Antioxidant enzymes activity, lipid peroxidation, oxidative damage in the testis and epididymis, and steroidogenesis in rats after co-exposure to atrazine and ethanol

Andrologia

Volumn 48, Issue 5, 2016, Pages 548-557

  Abarikwu, S O ^a   Duru, Q C ^a   Chinonso, O V ^a   Njoku, R C ^a  

^a UNIVERSITY OF PORT HARCOURT   (Nigeria)

Author keywords

Atrazine; Epididymis; Lipid peroxidation; Testis; Testosterone

Indexed keywords

ALCOHOL; ANTIOXIDANT; ATRAZINE; CATALASE; CHOLESTEROL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; HERBICIDE; HYDROXYSTEROID DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDIDYMIS; EXPOSURE; HISTOPATHOLOGY; HOMOGENATE; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PLASMA; RAT; STEROIDOGENESIS; TESTIS; ANIMAL; DRUG EFFECTS; DRUG POTENTIATION; METABOLISM; PATHOLOGY; WISTAR RAT;

17-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ATRAZINE; CATALASE; DRUG SYNERGISM; EPIDIDYMIS; ETHANOL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HERBICIDES; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TESTIS; TESTOSTERONE;

EID: 84941588327     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12478     Document Type: Article

References (55)

1. Abarikwu SO (2013) Causes and risk factors for male-factor infertility in Nigeria: a review. Afr J Reprod Health 17:150-166.
2. Abarikwu SO (2014) Protective effect of quercetin on atrazine-induced oxidative stress in the liver, kidney, brain, and heart of adult wistar rats. Toxicol Int 2:148-155.
3. Abarikwu SO, Farombi EO (2014) Quercetin ameliorates atrazine-induced changes in the testicular function of rats. Toxicol Ind Health doi: 10.1177/0748233714555389 (In press).
4. Abarikwu SO, Adesiyan AC, Oyeloja TO, Oyeyemi MO, Farombi EO (2010) Changes in sperm characteristics and induction of oxidative stress in the testis and epididymis of experimental rats by a herbicide, atrazine. Arch Environ Contam Toxicol 58:874-882.
5. Abarikwu SO, Farombi EO, Kashyap MP, Pant AB (2011) Kolaviron protects apoptotic cell death in PC12 cells exposed to atrazine. Free Radic Res 45:1061-1073.
6. Abarikwu SO, Pant AB, Farombi EO (2012a) Dietary antioxidant, quercetin, protects Sertoli-germ cell co-culture from atrazine-induced oxidative damage. J Biochem Mol Toxicol 26:477-485.
7. Abarikwu SO, Farombi EO, Pant AB (2012b) Kolaviron biflavanoids of Garcinia kola seeds protect atrazine-induced cytotoxicity in primary cultures of rat Leydig cells. Int J Toxicol 3:407-415.
8. Abarikwu SO, Pant AB, Farombi EO (2013a) Effects of quercetin on mRNA expression of steroidogenesis genes in primary cultures of Leydig cells treated with atrazine. Toxicol In Vitro 27:700-707.
9. Abarikwu SO, Pant AB, Farombi EO (2013b) Quercetin decreases steroidogenic enzyme activity, NF-κB expression, and oxidative stress in cultured Leydig cells exposed to atrazine. Mol Cell Biochem 37:19-28.
10. Abarikwu SO, Akiri OF, Durojaiye MA, Alabi AF (2015) Combined effects of repeated administration of Bretmont Wipeout (Glyphosate) and Ultrazin (Atrazine) on testosterone, oxidative stress and sperm quality of Wistar rats. Toxicol Mech Methods 25:70-80.
11. Alomary AA, Vallée M, O'Dell LE, Koob GF, Purdy RH, Fitzgerald RL (2003) Acutely administered ethanol participates in testosterone synthesis and increases testosterone in rat brain. Alcohol Clin Exp Res 27:38-43.
12. Bhatti JS, Sidhu IPS, Bhatti GK (2011) Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes. Mol Cell Biochem 353:139-149.
13. Brzóska MM, Galazyn-Sidorczuk M, Dzwilewska I (2011) Ethanol consumption modifies the body turnover of cadmium: a study in a rat model of human exposure. J Appl Toxicol 33:784-798.
14. Calabrese EJ, Baldwin LA (2001) Hormesis: a generalization and unifying hypothesis. Crit Rev Toxicol 31:353-424.
15. Campos-Pereira FD, Oliveira CA, Pigoso AA, Silva-Zacarin ECM, Barbieri R, Spatti EF, Marin-Morales MA, Severi-Aguiar GDC (2012) Early cytotoxic and genotoxic effects of atrazine on Wistar rat liver: a morphological, immunohistochemical, biochemical, and molecular study. Ecotoxicol Environ Saf 78:170-177.
16. Carlsen A, Givercman NK, Skakkebaek NE (1992) Evidence for decreasing quality of semen during past 50 years. Br Med J 305:609-613.
17. Chauhan A, Agarwal M, Kushwaha S, Mutreja A (2007) Suppression of fertility in male albino rats following the administration of 50% ethanolic extract of Aegle marmelos. Contraception 76:474-481.
18. Clairborne A (1995) Catalase activity. In: Handbook of Methods for Oxygen Radical Research. Greewald AR (ed). CRC Press, Boca Raton, FL, pp 237-242.
19. Eacker SM, Agrawal N, Qian K, Dichek HL, Gong EY, Lee K, Braun RE (2008) Hormonal regulation of testicular steroid and cholesterol homeostasis. Mol Endocrinol 22:623-635.
20. Eid NA, Shibata MA, Ito Y, Kusakabe K, Hammad H, Otsuki Y (2002) Involvement of Fas system and active caspases in apoptotic signalling in testicular germ cells of ethanol-treated rats. Int J Androl 25:159-167.
21. Erukainure OL, Ajiboye JA, Adejobi RO, Okafor OY, Adenekan SO (2011) Protective effect of pineapple (Ananas cosmosus) peel extract on alcohol-induced oxidative stress in brain tissues of male albino rats. Asian Pac J Trop Dis 1:5-9.
22. Farombi EO, Abarikwu SO, Adesiyan AC, Oyejola TO (2013) Quercetin exacerbates the effects of sub-acute treatment of atrazine on reproductive tissue antioxidant defence system, lipid peroxidation and sperm quality in rats. Andrologia 45:256-265.
23. Fisher JS (2004) Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome. Reproduction 7:1-24.
24. Friedmann AS (2002) Atrazine inhibition of testosterone production in rat males following peripubertal exposure. Reprod Toxicol 16:275-279.
25. Grattagliano G, Vendemiale G, Errico F, Bolognino AE, Lillo F, Salerno MT, Altomare E (1997) Chronic ethanol intake induces oxidative alterations in rat testis. J Appl Toxicol 17:307-311.
26. Grizard G, Artonne C, Grizard J, Boucher D (1997) Effect of short-term starvation on Leydig cell function in adult rats. Arch Androl 38:207-214.
27. Habig WH, Pabst MJ, Jacob WB (1974) Glutathione-s-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139.
28. Homan GF, Davies M, Norman R (2007) The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review. Hum Reprod Update 13:209-223.
29. Ikeda M (1995) Exposure to complex mixtures: implications for biological monitoring. Toxicol Lett 77:85-91.
30. Jeon WY, Shin IS, Shin HK, Lee MY (2014) Gastroprotective effect of the traditional herbal medicine, Sipjeondaebo-tang water extract, against ethanol induced gastric mucosal injury. BMC Complement Altern Med 14:373.
31. Jurczuk M, Brzoska MM, Moniuszko-Jakoniuk J, Galazyn-Sidorczuk M, Kulikowska-Karpinska E (2004) Antioxidant enzymes activity and lipid peroxidation in liver and kidney of rats exposed to cadmium and ethanol. Food Chem Toxicol 42:429-438.
32. Kniewald J, Jakominic M, Tomljenovic A, Simic P, Romac P, Vranesic D, Kniewald Z (2000) Disorders of male rat reproductive tract under the influence of atrazine. J Appl Toxicol 20:61-68.
33. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with folin phenol reagent. J Biol Chem 193:265-275.
34. Mishra RK, Singh SK (2009) Antispermatogenic and anti-fertility effects of fruits of Piper nigrum L. in mice. Indian J Exp Biol 47:706-714.
35. Misra HP, Fridovich I (1972) The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170-3175.
36. Oh HG, Lee HY, Kim JH, Kang YR, Moon DI, Seo MY, Back HI, Kim SY, Oh MR, Park SH, Kim MG, Jeon JY, Shin SJ, Ryu KS, Chae SW, Kim O, Park JK (2012) Effects of male silkworm pupa powder on the erectile dysfunction by chronic ethanol consumption in rats. Lab Anim Res 28:83-90.
37. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358.
38. Oliva SU, Messias AG, Silva DA, Pereira OC, Gerardin DC, Kempinas WG (2006) Impairment of adult male reproductive function in rats exposed to ethanol since puberty. Reprod Toxicol 22:599-605.
39. Park H-O, Bae J (2012) Disturbed relaxin signaling pathway and testicular dysfunction in mouse offspring upon maternal exposure to simazine. PLoS ONE 7:e44856.
40. Reis MM, Moreira AC, Sousa M, Mathur PP, Oliveira PF, Alves MG (2015) Sertoli cell as a model in male reproductive toxicology: advantages and disadvantages. J Appl Toxicol 35:870-883.
41. Rhind SM (2002) Endocrine disrupting compounds and farm animals: their properties, actions and routes of exposure. Domest Anim Endocrinol 23:179-187.
42. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588-590.
43. Sarkar M, Gangopadhyay M, Basak B, Chakrabarty K, Banerji J, Adhikary P, Chatterjee A (2000) The reversible anti-fertility effects of Piper betle Linn on Swiss albino male mice. Contraception 62:271-274.
44. Sarkola T, Adlercreutz H, Heinonen S, von der Pahlen B, Eriksson CJP (2001) The role of the liver in the acute effect of alcohol on androgens in women. J Clin Endocrinol Metab 86:1981-1985.
45. Sedlak J, Lindsay RH (1968) Estimation of total, protein-bound and non-protein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 25:192-205.
46. Sharma R, Biedenharn KR, Fedor JM, Agarwal A (2013) Lifestyle factors and reproductive health: taking control of your fertility. Reprod Biol Endocrinol 11:66.
47. Sharpe RM (2000) Lifestyle and environmental contribution to male infertility. Br Med Bull 56:630-642.
48. Shi Q, Emanuele NV, Emanuele MA (1998) Effect of nitric oxide synthase inhibitors on preventing ethanol-induced suppression of the hypothalamic-pituitary-gonadal axis in the male rat. Alcohol Clin Exp Res 22:1763-1770.
49. Siervo GE, Vieira HR, Ogo FM, Fernandez CD, Gonçalves GD, Mesquita SF, Anselmo-Franci JA, Cecchini R, Guarnier FA, Fernandes GS (2015) Spermatic and testicular damages in rats exposed to ethanol: influence of lipid peroxidation but not testosterone. Toxicology 330:1-8.
50. Singh M, Sandhir R, Kiran R (2011) Effects on antioxidant status of liver following atrazine exposure and its attenuation by vitamin E. Exp Toxicol Pathol 63:269-276.
51. Tchounwou PB, Wilson BA, Ishaque AB, Schneider J (2001) Atrazine potentiation of arsenic trioxide-induced cytotoxicity and gene expression in human liver carcinoma cells (HepG2). Mol Cell Biochem 222:49-59.
52. Toppari J, Larsen JC, Christiansen P, Giwercman A, Grandjean P, Guillette LJ, Jégou B, Jensen TK, Jouannet P, Keiding N, Leffers H, McLachlan JA, Meyer O, Müller J, Rajpert-De Meyts E, Scheike T, Sharpe R, Sumpter J, Skakkebaek NE (1996) Male reproductive health and environmental xenoestrogens. Environ Health Perspect 104:741-803.
53. Uygur R, Yagmurca M, Alkoc OA, Genc A, Songur A, Ucok K, Ozen OA (2014) Effects of quercetin and fish n-3 fatty acids on testicular injury induced by ethanol in rats. Andrologia 46:356-369.
54. Victor-Costa AB, Bandeira SMC, Oliveira AG, Mahecha GAB, Oliveira CA (2010) Changes in testicular morphology and steroidogenesis in adult rats exposed to atrazine. Reprod Toxicol 29:323-331.
55. Zirkin RB, Stephanie VT, Andrew SF, Robert TY, Charles BB (2001) Atrazine effects on testosterone levels and androgen-dependent reproductive organs in peripubertal male rats. J Androl 22:142-148.