Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects

Lipids in Health and Disease

Volumn 14, Issue 1, 2015, Pages

  Domínguez Reyes, Teresa ^a   Astudillo López, Constanza C ^a   Salgado Goytia, Lorenzo ^a   Muñoz Valle, José F ^b   Salgado Bernabé, Aralia B ^a   Guzmán Guzmán, Iris P ^a   Castro Alarcón, Natividad ^a   Moreno Godínez, Ma E ^a   Parra Rojas, Isela ^a  

^a UNIVERSIDAD AUTÓNOMA DE GUERRERO   (Mexico)

^b UNIVERSITY OF GUADALAJARA   (Mexico)

Author keywords

APOA2; APOA5; Dyslipidemia; Gene diet interaction; LEPR; Obesity

Indexed keywords

APOLIPOPROTEIN A2; APOLIPOPROTEIN A5; CHOLESTEROL; SATURATED FATTY ACID; TRIACYLGLYCEROL; APOA2 PROTEIN, HUMAN; APOA5 PROTEIN, HUMAN; APOLIPOPROTEIN A; FAT INTAKE; FATTY ACID; GLUCOSE BLOOD LEVEL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN RECEPTOR; LEPTIN RECEPTOR, HUMAN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ANTHROPOMETRY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CONTROLLED STUDY; DYSLIPIDEMIA; ENVIRONMENTAL FACTOR; FAT INTAKE; FEMALE; FOOD INTAKE; GENE; GENE FREQUENCY; GENE INTERACTION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; LEPR GENE; LIPID DIET; MAJOR CLINICAL STUDY; MALE; OBESITY; POLYMERASE CHAIN REACTION; PROTEIN PROTEIN INTERACTION; QUESTIONNAIRE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL; YOUNG ADULT; ADOLESCENT; ADVERSE EFFECTS; BLOOD; CASE CONTROL STUDY; DIET RESTRICTION; DYSLIPIDEMIAS; GENE EXPRESSION; GENETICS; GLUCOSE BLOOD LEVEL; METABOLISM; PATHOLOGY; RISK; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; APOLIPOPROTEIN A-II; APOLIPOPROTEIN A-V; APOLIPOPROTEINS A; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIET, HIGH-FAT; DIETARY FATS; DYSLIPIDEMIAS; FASTING; FATTY ACIDS; FEMALE; GENE EXPRESSION; GENOTYPE; HUMANS; MALE; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, LEPTIN; RISK; SURVEYS AND QUESTIONNAIRES; TRIGLYCERIDES;

EID: 84941554733     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/s12944-015-0112-4     Document Type: Article

References (43)

1. Fall T, Ingelsson E. Genome-wide association studies of obesity and metabolic syndrome. Mol Cell Endocrinol. 2014;382:740-57.
2. Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, et al. The human obesity gene map: the 2005 update. Obesity. 2006;14:529-644.
3. Qi L, Cho YA. Gene-environment interaction and obesity. Nutr Rev. 2008;66:684-94.
4. Yang W, Kelly T, He J. Genetic epidemiology of obesity. Epidemiol Rev. 2007;29:49-61.
5. Ordovas JM, Corella D. Nutritional genomics. Annu Rev Genomics Hum Genet. 2004;5:71-118.
6. Ordovas JM. Nutrigenetics, plasma lipids, and cardiovascular risk. J Am Diet Assoc. 2006;106:1074-81.
7. WHo J, Consultation FE. Diet, nutrition and the prevention of chronic diseases. WHO Tech Rep Ser. 2003;916:1-60.
8. Ordovas JM. Genotype-phenotype associations: modulation by diet and obesity. Obesity. 2008;16:S40-6.
9. Furusawa T, Naka I, Yamauchi T, Natsuhara K, Kimura R, Nakazawa M, et al. The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders. Hum Genet. 2010;127:287-94.
10. O'Brien PJ, Alborn WE, Sloan JH, Ulmer M, Boodhoo A, Knierman MD, et al. The novel apolipoprotein A5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins. Clin Chem. 2005;51:351-9.
11. Grallert H, Sedlmeier E-M, Huth C, Kolz M, Heid IM, Meisinger C, et al. APOA5 variants and metabolic syndrome in Caucasians. J Lipid Res. 2007;48:2614-21.
12. Ong KL, Jiang CQ, Liu B, Jin YL, Tso AW, Tam S, et al. Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese. Clin Endocrinol (Oxf). 2011;74:206-13.
13. Martín-Campos JM, Ribas V, Blanco-Vaca F, et al. Apolipoprotein A-II, genetic variation on chromosome 1q21-q24, and disease susceptibility. Curr Opin Lipidol. 2004;15:247-53.
14. Zaki ME, Amr KS, Abdel-Hamid M. APOA2 Polymorphism in Relation to Obesity and Lipid Metabolism. Cholesterol. 2013;2013:289481.
15. Spiegelman BM, Flier JS. Obesity and the regulation of energy balance. Cell. 2001;104:531-43.
16. Tucker KL. Assessment of usual dietary intake in population studies of gene-diet interaction. Nutr Metab Cardiovasc Dis. 2007;17:74-81.
17. Peloso GM, Demissie S, Collins D, Mirel DB, Gabriel SB, Cupples LA, et al. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. J Lipid Res. 2010;51:3524-32.
18. Maljaars J, Romeyn EA, Haddeman E, Peters HP, Masclee AA. Effect of fat saturation on satiety, hormone release, and food intake. Am J Clin Nutr. 2009;89:1019-24.
19. Woods SC, Seeley RJ, Rushing PA, D'Alessio D, Tso P. A controlled high-fat diet induces an obese syndrome in rats. J Nutr. 2003;133:1081-7.
20. Pennacchio LA, Olivier M, Hubacek JA, Krauss RM, Rubin EM, Cohen JC. Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet. 2002;11:3031-8.
21. De Andrade FM, Maluf SW, Schuch JB, Voigt F, Barros AC, Lucatelli JF, et al. The influence of the S19W SNP of the APOA5 gene on triglyceride levels in southern Brazil: interactions with the APOE gene, sex and menopause status. Nutr Metab Cardiovasc Dis. 2011;21:584-90.
22. de Oliveira R, Cerda A, Genvigir FDV, Sampaio MF, Armaganijan D, Bernik MMS, et al. Leptin receptor gene polymorphisms are associated with adiposity and metabolic alterations in Brazilian individuals. Arq Bras Endocrinol Metabol. 2013;57:677-84.
23. Mizuta E, Kokubo Y, Yamanaka I, Miyamoto Y, Okayama A, Yoshimasa Y, et al. Leptin gene and leptin receptor gene polymorphisms are associated with sweet preference and obesity. Hypertens Res. 2008;31:1069-77.
24. Price AL, Patterson N, Yu F, Cox DR, Waliszewska A, McDonald GJ, et al. A genomewide admixture map for Latino populations. Am J Hum Genet. 2007;80:1024-36.
25. Fruchart-Najib J, Bauge E, Niculescu L-S, Pham T, Thomas B, Rommens C, et al. Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5. Biochem Biophys Res Commun. 2004;319:397-404.
26. Ishihara M, Kujiraoka T, Iwasaki T, Nagano M, Takano M, Ishii J, et al. A sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein AV concentration. J Lipid Res. 2005;46:2015-22.
27. Mattei J, Demissie S, Tucker KL, Ordovas JM. Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults. J Nutr. 2009;139:2301-8.
28. Sánchez-Moreno C, Ordovás JM, Smith CE, Baraza JC, Lee Y-C, Garaulet M. APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. J Nutr. 2011;141:380-5.
29. Pennacchio LA, Rubin EM. Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice. Arterioscler Thromb Vasc Biol. 2003;23:529-34.
30. Van den Berg SA, Heemskerk MM, Geerling JJ, van Klinken J-B, Schaap FG, Bijland S, et al. Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake. FASEB J. 2013;27:3354-62.
31. Tartaglia LA. The leptin receptor. J Biol Chem. 1997;272:6093-6.
32. Meister B. Control of food intake via leptin receptors in the hypothalamus. Vitam Horm. 2000;59:265-304.
33. Murugesan D, Arunachalam T, Ramamurthy V, Subramanian S. Association of polymorphisms in leptin receptor gene with obesity and type 2 diabetes in the local population of Coimbatore. Indian J Hum Genet. 2010;16:72.
34. Yiannakouris N, Yannakoulia M, Melistas L, Chan JL, Klimis-Zacas D, Mantzoros CS. The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability. J Clin Endocrinol Metab. 2001;86:4434-9.
35. Stenger C, Hanse M, Pratte D, Mbala M-L, Akbar S, Koziel V, et al. Up-regulation of hepatic lipolysis stimulated lipoprotein receptor by leptin: a potential lever for controlling lipid clearance during the postprandial phase. FASEB J. 2010;24:4218-28.
36. Corella D, Arnett DK, Tsai MY, Kabagambe EK, Peacock JM, Hixson JE, et al. The -256 T∈>∈C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. Clin Chem. 2007;53:1144-52.
37. Tso P, Liu M, John Kalogeris T, Thomson AB. The role of apolipoprotein A-IV in the regulation of food intake. Annu Rev Nutr. 2001;21:231-54.
38. Corella D, Peloso G, Arnett DK, Demissie S, Cupples LA, Tucker K, et al. APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med. 2009;169:1897-906.
39. Corella D, Lai C-Q, Demissie S, Cupples LA, Manning AK, Tucker KL, et al. APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. J Mol Med. 2007;85:119-28.
40. Corella D, Tai ES, Sorlí JV, Chew SK, Coltell O, Sotos-Prieto M, et al. Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asian populations: replication of a gene-saturated fat interaction. Int J Obes. 2011;35:666-75.
41. Rodríguez-Ramírez S, Mundo-Rosas V, Jiménez-Aguilar A, Shamah-Levy T. Methodology for the analysis of dietary data from the Mexican National Health and Nutrition Survey 2006. Salud Publica Mex. 2009;51:S523-9.
42. Untergasser A, Cutcutache I, Koressaar T, Ye J, Faircloth BC, Remm M, et al. Primer3 - new capabilities and interfaces. Nucleic Acids Res. 2012;40:e115.
43. Vincze T, Posfai J, Roberts RJ. NEBcutter: a program to cleave DNA with restriction enzymes. Nucleic Acids Res. 2003;31:3688-91.