Extended synaptotagmin interaction with the fibroblast growth factor receptor depends on receptor conformation, not catalytic activity

Journal of Biological Chemistry

Volumn 290, Issue 26, 2015, Pages 16142-16156

  Tremblay, Michel G ^a,b   Herdman, Chelsea ^a,b   Guillou, François ^a,b   Mishra, Prakash K ^a,b   Baril, Joëlle ^a,b   Bellenfant, Sabrina ^a,b   Moss, Tom ^a,b  

^a University Laval   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; ENZYMES;

ACTIVATION LOOPS; AUTOPHOSPHORYLATION; ENDOPLASMIC RETICULUM; FIBROBLAST GROWTH FACTOR RECEPTORS; HOMODIMERIZATION; RECEPTOR ACTIVATION; TRANS-MEMBRANE DOMAINS; XENOPUS EMBRYO;

CATALYST ACTIVITY;

EXTENDED SYNAPTOTAGMIN; EXTENDED SYNAPTOTAGMIN 1; EXTENDED SYNAPTOTAGMIN 2; EXTENDED SYNAPTOTAGMIN 3; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MEMBRANE PROTEIN; PHOSPHOTRANSFERASE; SYNAPTOTAGMIN; UNCLASSIFIED DRUG; ESYT1 PROTEIN, HUMAN; ESYT3 PROTEIN, HUMAN; FAM62B PROTEIN, HUMAN; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CONTROLLED STUDY; DIMERIZATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HEK293 CELL LINE; IN VIVO STUDY; MCF 7 CELL LINE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; ENDOPLASMIC RETICULUM; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; SEQUENCE ALIGNMENT; SYNAPTOTAGMINS;

EID: 84941362427     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.656918     Document Type: Article

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