Olfactomedin 4 serves as a marker for disease severity in pediatric respiratory syncytial virus (RSV) infection

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Brand, H K ^a,b   Ahout, I M L ^a,b   De Ridder, D ^c   Van Diepen, A ^a,b   Li, Y ^d   Zaalberg, M ^a   Andeweg, A ^d   Roeleveld, N ^a   De Groot, R ^a,b   Warris, A ^a,b   Hermans, P W M ^a,b   Ferwerda, G ^a,b   Staal, F J T ^d,e  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Department of Microelectronics   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GRANULOCYTE COLONY STIMULATING FACTOR; OLFM4 PROTEIN, HUMAN;

ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIFFERENTIALLY EXPRESSED GENE; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENOME ANALYSIS; GESTATIONAL AGE; HUMAN; IMMUNOCOMPETENT CELL; INFANT; INNATE IMMUNITY; LENGTH OF STAY; MALE; MARKER GENE; MICROARRAY ANALYSIS; NATURAL KILLER CELL; OLFM4 GENE; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; VALIDATION PROCESS; WINTER; ARTIFICIAL VENTILATION; BLOOD; GENETICS; HOSPITALIZATION; PATHOLOGY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SEVERITY OF ILLNESS INDEX;

BIOMARKERS; FEMALE; GENE EXPRESSION; GRANULOCYTE COLONY-STIMULATING FACTOR; HOSPITALIZATION; HUMANS; INFANT; MALE; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SEVERITY OF ILLNESS INDEX;

EID: 84941346658     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131927     Document Type: Article

References (42)

1. Henrickson KJ, Hoover S, Kehl KS, Hua W. National disease burden of respiratory viruses detected in children by polymerase chain reaction. Pediatr Infect Dis J. 2004; 23(1 Suppl):S11-8. PMID: 14730265
2. Iwane MK, Edwards KM, Szilagyi PG, Walker FJ, Griffin MR, Weinberg GA, et al. Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children. Pediatrics. 2004; 113(6):1758-64. PMID: 15173503
3. Shay DK, Holman RC, Newman RD, Liu LL, Stout JW, Anderson LJ. Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA: the journal of the American Medical Association. 1999; 282(15):1440-6.
4. Black CP. Systematic review of the biology and medical management of respiratory syncytial virus infection. Respiratory care. 2003; 48(3):209-31; discussion 31-3. PMID: 12667273
5. Boyce TG, Mellen BG, Mitchel EF Jr., Wright PF, Griffin MR. Rates of hospitalization for respiratory syncytial virus infection among children in medicaid. J Pediatr. 2000; 137(6):865-70. PMID: 11113845
6. Wang EE, Law BJ, Stephens D. Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection. J Pediatr. 1995; 126(2):212-9. PMID: 7844667
7. Berger TM, Aebi C, Duppenthaler A, Stocker M, Swiss Pediatric Surveillance U. Prospective population- based study of RSV-related intermediate care and intensive care unit admissions in Switzerland over a 4-year period (2001-2005). Infection. 2009; 37(2):109-16. doi: 10.1007/s15010-008-8130-z PMID: 19412586
8. Prais D, Danino D, Schonfeld T, Amir J. Impact of palivizumab on admission to the ICU for respiratory syncytial virus bronchiolitis: a national survey. Chest. 2005; 128(4):2765-71. PMID: 16236953
9. Lopez Guinea A, Casado Flores J, Martin Sobrino MA, Espinola Docio B, de la Calle Cabrera T, Serrano A, et al. [Severe bronchiolitis. Epidemiology and clinical course of 284 patients]. Anales de pediatria. 2007; 67(2):116-22. PMID: 17692256
10. Mansbach JM, Clark S, Christopher NC, LoVecchio F, Kunz S, Acholonu U, et al. Prospective multicenter study of bronchiolitis: predicting safe discharges from the emergency department. Pediatrics. 2008; 121(4):680-8. doi: 10.1542/peds.2007-1418 PMID: 18381531
11. Norwood A, Mansbach JM, Clark S, Waseem M, Camargo CA Jr. Prospective multicenter study of bronchiolitis: predictors of an unscheduled visit after discharge from the emergency department. Acad Emerg Med. 2010; 17(4):376-82. doi: 10.1111/j.1553-2712.2010.00699.x PMID: 20370776
12. Roback MG, Baskin MN. Failure of oxygen saturation and clinical assessment to predict which patients with bronchiolitis discharged from the emergency department will return requiring admission. Pediatric emergency care. 1997; 13(1):9-11. PMID: 9061726
13. Openshaw PJ, Tregoning JS. Immune responses and disease enhancement during respiratory syncytial virus infection. Clinical microbiology reviews. 2005; 18(3):541-55. PMID: 16020689
14. Kim Brand H, Ferwerda G, Preijers F, de Groot R, Neeleman C, Staal FJ, et al. CD4+ T-cell counts, interleukin-8 and CCL-5 plasma concentrations discriminate disease severity in children with RSVinfection. Pediatr Res. 2012.
15. Hoggatt J. Personalized medicine-trends in molecular diagnostics: exponential growth expected in the next ten years. Molecular diagnosis & therapy. 2011; 15(1):53-5.
16. Quinn B. Payers and the assessment of clinical utility for companion diagnostics. Clinical pharmacology and therapeutics. 2010; 88(6):751-4. doi: 10.1038/clpt.2010.234 PMID: 21081944
17. Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000; 403(6769):503-11. PMID: 10676951
18. Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, Mejias A, et al. Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. The Journal of experimental medicine. 2007; 204(9):2131-44. PMID: 17724127
19. Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, Baldwin N, et al. A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity. 2008; 29(1):150-64. doi: 10.1016/j.immuni.2008.05.012 PMID: 18631455
20. Ramilo O, Allman W, Chung W, Mejias A, Ardura M, Glaser C, et al. Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood. 2007; 109(5):2066-77. PMID: 17105821
21. Mejias A, Dimo B, Suarez NM, Garcia C, Suarez-Arrabal MC, Jartti T, et al. Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection. PLoS medicine. 2013; 10(11):e1001549. doi: 10.1371/journal.pmed.1001549 PMID: 24265599
22. Templeton KE, Scheltinga SA, Beersma MF, Kroes AC, Claas EC. Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza a and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4. Journal of clinical microbiology. 2004; 42 (4):1564-9. PMID: 15071005
23. Staal FJ, Weerkamp F, Baert MR, van den Burg CM, van Noort M, de Haas EF, et al. Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J Immunol. 2004; 172(2):1099-108. PMID: 14707084
24. Staal FJ, de Ridder D, Szczepanski T, Schonewille T, van der Linden EC, van Wering ER, et al. Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype. Leukemia. 2010; 24(3):491-9. doi: 10.1038/leu.2009.286 PMID: 20072147
25. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001; 98(19):10869-74. PMID: 11553815
26. Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 2001; 98(9):5116-21. PMID: 11309499
27. Grover PK, Hardingham JE, Cummins AG. Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis. Cancer metastasis reviews. 2010; 29(4):761-75. doi: 10. 1007/s10555-010-9262-z PMID: 20878207
28. Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic acids research. 2002; 30(1):207-10. PMID: 11752295
29. Parkinson H, Sarkans U, Kolesnikov N, Abeygunawardena N, Burdett T, Dylag M, et al. ArrayExpress update-an archive of microarray and high-throughput sequencing-based functional genomics experiments. Nucleic acids research. 2011; 39(Database issue):D1002-4. doi: 10.1093/nar/gkq1040 PMID: 21071405
30. Robbins AS, Chao SY, Fonseca VP. What's the relative risk? A method to directly estimate risk ratios in cohort studies of common outcomes. Annals of epidemiology. 2002; 12(7):452-4. PMID: 12377421
31. Ioannidis I, McNally B, Willette M, Peeples ME, Chaussabel D, Durbin JE, et al. Plasticity and virus specificity of the airway epithelial cell immune response during respiratory virus infection. Journal of virology. 2012; 86(10):5422-36. doi: 10.1128/JVI.06757-11 PMID: 22398282
32. Zilliox MJ, Moss WJ, Griffin DE. Gene expression changes in peripheral blood mononuclear cells during measles virus infection. Clinical and vaccine immunology: CVI. 2007; 14(7):918-23. PMID: 17538120
33. Wang Y, Dennehy PH, Keyserling HL, Tang K, Gentsch JR, Glass RI, et al. Rotavirus infection alters peripheral T-cell homeostasis in children with acute diarrhea. Journal of virology. 2007; 81(8):3904-12. PMID: 17267507
34. Zaas AK, Chen M, Varkey J, Veldman T, Hero AO 3rd, Lucas J, et al. Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell host & microbe. 2009; 6(3):207-17.
35. Zhang J, Liu WL, Tang DC, Chen L, Wang M, Pack SD, et al. Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development. Gene. 2002; 283(1-2):83-93. PMID: 11867215
36. Gersemann M, Becker S, Nuding S, Antoni L, Ott G, Fritz P, et al. Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD. Journal of Crohn's & colitis. 2012; 6(4):425-34.
37. Mannick EE, Schurr JR, Zapata A, Lentz JJ, Gastanaduy M, Cote RL, et al. Gene expression in gastric biopsies from patients infected with Helicobacter pylori. Scandinavian journal of gastroenterology. 2004; 39(12):1192-200. PMID: 15742995
38. Liu W, Yan M, Liu Y, Wang R, Li C, Deng C, et al. Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(24):11056-61. doi: 10.1073/pnas.1001269107 PMID: 20534456
39. Liu W, Yan M, Liu Y, McLeish KR, ColemanWG Jr., Rodgers GP. Olfactomedin 4 inhibits cathepsin Cmediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice. J Immunol. 2012; 189(5):2460-7. doi: 10.4049/jimmunol.1103179 PMID: 22844115
40. Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 2012; 148(6):1293-307. doi: 10.1016/j.cell.2012.02. 009 PMID: 22424236
41. Clemmensen SN, Bohr CT, Rorvig S, Glenthoj A, Mora-Jensen H, Cramer EP, et al. Olfactomedin 4 defines a subset of human neutrophils. Journal of leukocyte biology. 2012; 91(3):495-500. doi: 10. 1189/jlb.0811417 PMID: 22187488
42. Brand HK, Hermans PW, de Groot R. Host biomarkers and paediatric infectious diseases: from molecular profiles to clinical application. Advances in experimental medicine and biology. 2010; 659:19-31. doi: 10.1007/978-1-4419-0981-7-2 PMID: 20204752