Cross sectional and longitudinal associations between cardiovascular risk factors and age related macular degeneration in the EPICNorfolk eye study

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Yip, Jennifer L Y ^a,b   Khawaja, Anthony P ^a,b   Chan, Michelle P Y ^b   Broadway, David C ^c   Peto, Tunde ^b   Tufail, Adnan ^b   Luben, Robert ^a   Hayat, Shabina ^a   Bhaniani, Amit ^a   Wareham, Nicholas J ^d   Khaw, Kay Tee ^a   Foster, Paul J ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGE RELATED MACULAR DEGENERATION; AGED; ARTICLE; AUSTRALIA; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; EDUCATION; EUROPE; FEMALE; FOLLOW UP; HUMAN; LIFESTYLE MODIFICATION; LONGITUDINAL STUDY; MALE; PREVALENCE; PROSPECTIVE STUDY; RISK FACTOR; SMOKING; SYSTOLIC BLOOD PRESSURE; UNITED STATES; CARDIOVASCULAR DISEASES; COMPLICATION; ENGLAND; MACULAR DEGENERATION; MIDDLE AGED; MULTIVARIATE ANALYSIS; STATISTICAL MODEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; ENGLAND; FEMALE; FOLLOW-UP STUDIES; HUMANS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MACULAR DEGENERATION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RISK FACTORS;

EID: 84941340935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132565     Document Type: Article

References (42)

1. Pascolini D, Mariotti SP Global estimates of visual impairment: 2010. Br J Ophthalmol 96: 614-618.
2. Owen CG, Jarrar Z, Wormald R, Cook DG, Fletcher AE, Rudnicka AR (2012) The estimated prevalence and incidence of late stage age related macular degeneration in the UK. Br J Ophthalmol 96: 752-756. doi: 10.1136/bjophthalmol-2011-301109 PMID: 22329913
3. Friedman DS, O'Colmain BJ, Munoz B, Tomany SC, McCarty C, de Jong PT, et al. (2004) Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122: 564-572. PMID: 15078675
4. Tomany SC, Wang JJ, Van Leeuwen R, Klein R, Mitchell P, Vingerling JR, et al. (2004) Risk factors for incident age-related macular degeneration: pooled findings from 3 continents. Ophthalmology 111: 1280-1287. PMID: 15234127
5. Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY (2012) Age-related macular degeneration. Lancet 379: 1728-1738. doi: 10.1016/S0140-6736(12)60282-7 PMID: 22559899
6. Smith W, Assink J, Klein R, Mitchell P, Klaver CC, Klein BE, et al. (2001) Risk factors for age-related macular degeneration: Pooled findings from three continents. Ophthalmology 108: 697-704. PMID: 11297486
7. Klein R, Deng Y, Klein BEK, Hyman L, Seddon J, Frank RN, et al. (2007) Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study. American journal of ophthalmology 143: 473-483. PMID: 17317391
8. Cackett P, Wong TY, Aung T, Saw S-M, Tay WT, Rochtchina E, et al. (2008) Smoking, cardiovascular risk factors, and age-related macular degeneration in Asians: the Singapore Malay Eye Study. American journal of ophthalmology 146: 960-967.e961. doi: 10.1016/j.ajo.2008.06.026 PMID: 18723144
9. Fraser-Bell S, Wu J, Klein R, Azen SP, Hooper C, Foong AWP, et al. (2008) Cardiovascular risk factors and age-related macular degeneration: the Los Angeles Latino Eye Study. American journal of ophthalmology 145: 308-316. doi: 10.1016/j.ajo.2007.10.007 PMID: 18222193
10. Hogg RE, Woodside JV, Gilchrist SECM, Graydon R, Fletcher AE, Chan W, et al. (2008) Cardiovascular disease and hypertension are strong risk factors for choroidal neovascularization. Ophthalmology 115: 1046-1052.e1042. PMID: 17953990
11. Sun C, Klein R, Wong TY (2009) Age-related macular degeneration and risk of coronary heart disease and stroke: the Cardiovascular Health Study. Ophthalmology 116: 1913-1919. doi: 10.1016/j.ophtha. 2009.03.046 PMID: 19592102
12. Seddon JM, George S, Rosner B, Klein ML (2006) CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered 61: 157-165. PMID: 16816528
13. Chakravarthy U, Wong TY, Fletcher A, Piault E, Evans C, Zlateva G, et al. (2010) Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis. BMC ophthalmology 10: 31. doi: 10.1186/1471-2415-10-31 PMID: 21144031
14. Wong TY, Klein R, Sun C, Mitchell P, Couper DJ, Lai H, et al. (2006) Age-related macular degeneration and risk for stroke. Annals of internal medicine 145: 98-106. PMID: 16847292
15. Mitta VP, Christen WG, Glynn RJ, Semba RD, Ridker PM, Rimm EB, et al. (2013) C-reactive protein and the incidence of macular degeneration: pooled analysis of 5 cohorts. JAMA ophthalmology 131: 507-513. doi: 10.1001/jamaophthalmol.2013.2303 PMID: 23392454
16. Hong T, Tan AG, Mitchell P, Wang JJ (2011) A review and meta-analysis of the association between Creactive protein and age-related macular degeneration. Surv Ophthalmol 56: 184-194. doi: 10.1016/j. survophthal.2010.08.007 PMID: 21420705
17. Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPEBruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 20: 705-732. PMID: 11587915
18. Neale BM, Fagerness J, Reynolds R, Sobrin L, Parker M, Raychaudhuri S, et al. (2010) Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc Natl Acad Sci U S A 107: 7395-7400. doi: 10.1073/pnas.0912019107 PMID: 20385826
19. van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, van Duijn CM, Stricker BH, et al. (2004) Cholesterol and age-related macular degeneration: is there a link? Am J Ophthalmol 137: 750-752. PMID: 15059717
20. Delcourt C, Michel F, Colvez A, Lacroux A, Delage M, Vernet MH, et al. (2001) Associations of cardiovascular disease and its risk factors with age-related macular degeneration: the POLA study. Ophthalmic Epidemiol 8: 237-249. PMID: 11471092
21. Hyman L, Schachat AP, He Q, Leske MC (2000) Hypertension, cardiovascular disease, and agerelated macular degeneration. Age-Related Macular Degeneration Risk Factors Study Group. Arch Ophthalmol 118: 351-358. PMID: 10721957
22. Klein R, Klein BE, Tomany SC, Cruickshanks KJ (2003) The association of cardiovascular disease with the long-term incidence of age-related maculopathy: the Beaver Dam eye study. Ophthalmology 110: 636-643. PMID: 12689879
23. Cougnard-Gregoire A, Delyfer MN, Korobelnik JF, Rougier MB, Le Goff M, Dartigues JF, et al. (2014) Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study. PLoS One 9: e90973. doi: 10.1371/journal.pone.0090973 PMID: 24608419
24. Klein R, Cruickshanks KJ, Nash SD, Krantz EM, Nieto FJ, Huang GH, et al. (2010) The prevalence of age-related macular degeneration and associated risk factors. Archives of ophthalmology 128: 750-758. doi: 10.1001/archophthalmol.2010.92 PMID: 20547953
25. Reynolds R, Rosner B, Seddon JM (2010) Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration. Ophthalmology 117: 1989-1995. doi: 10.1016/j.ophtha. 2010.07.009 PMID: 20888482
26. Tan JS, Mitchell P, Smith W, Wang JJ (2007) Cardiovascular risk factors and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology 114: 1143-1150. PMID: 17275090
27. Day N, Oakes S, Luben R, Khaw KT, Bingham S, Welch A, et al. (1999) EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer. Br J Cancer 80 Suppl 1: 95-103. PMID: 10466767
28. Khawaja AP, Chan MP, Hayat S, Broadway DC, Luben R, Garway-Heath DF, et al. (2013) The EPICNorfolk Eye Study: rationale, methods and a cross-sectional analysis of visual impairment in a population- based cohort. BMJ Open 3.
29. Hayat SA, Luben R, Keevil VL, Moore S, Dalzell N, Bhaniani A, et al. (2013) Cohort Profile: A prospective cohort study of objective physical and cognitive capability and visual health in an ageing population of men and women in Norfolk (EPIC-Norfolk 3). Int J Epidemiol 43: 1063-1072. doi: 10.1093/ije/dyt086 PMID: 23771720
30. Khaw KT, Jakes R, Bingham S, Welch A, Luben R, Day N, et al. (2006) Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective population study. Int J Epidemiol 35: 1034-1043. PMID: 16709620
31. Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD, et al. (1995) An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 39: 367-374. PMID: 7604360
32. Klein R, Klein BE, Linton KL (1992) Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology 99: 933-943. PMID: 1630784
33. Mitchell P, Smith W, Attebo K, Wang JJ (1995) Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study. Ophthalmology 102: 1450-1460. PMID: 9097791
34. Vingerling JR, Dielemans I, Hofman A, Grobbee DE, Hijmering M, Kramer CF, et al. (1995) The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology 102: 205-210. PMID: 7862408
35. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308: 419-421. PMID: 15761120
36. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-389. PMID: 15761122
37. Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, et al. (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 38: 458-462. PMID: 16518403
38. Maller JB, Fagerness JA, Reynolds RC, Neale BM, Daly MJ, Seddon JM (2007) Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 39: 1200-1201. PMID: 17767156
39. Fagerness JA, Maller JB, Neale BM, Reynolds RC, Daly MJ, Seddon JM (2009) Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet 17: 100-104. doi: 10.1038/ ejhg.2008.140 PMID: 18685559
40. Navab M, Reddy ST, Van Lenten BJ, Fogelman AM (2011) HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol 8: 222-232. doi: 10.1038/nrcardio.2010.222 PMID: 21304474
41. Corsetti JP, Zareba W, Moss AJ, Rainwater DL, Sparks CE (2006) Elevated HDL is a risk factor for recurrent coronary events in a subgroup of non-diabetic postinfarction patients with hypercholesterolemia and inflammation. Atherosclerosis 187: 191-197. PMID: 16242700
42. Corsetti JP, Ryan D, Rainwater DL, Moss AJ, Zareba W, Sparks CE (2010) Cholesteryl ester transfer protein polymorphism (TaqIB) associates with risk in postinfarction patients with high C-reactive protein and high-density lipoprotein cholesterol levels. Arterioscler Thromb Vasc Biol 30: 1657-1664. doi: 10. 1161/ATVBAHA.110.207977 PMID: 20489166