메뉴 건너뛰기




Volumn 232, Issue 20, 2015, Pages 3821-3831

Pituitary adenylate cyclase-activating polypeptide induces a depressive-like phenotype in rats

Author keywords

Anhedonia; Animal model; Depression; Despair; Intracranial self stimulation (ICSS); PAC1; PACAP; Reward

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; ADENYLATE CYCLASE;

EID: 84941317293     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-015-4045-4     Document Type: Article
Times cited : (23)

References (71)
  • 1
    • 0030995283 scopus 로고    scopus 로고
    • Effect of adrenalectomy on cocaine facilitation of lateral hypothalamic self-stimulation
    • 1:CAS:528:DyaK2sXisVemsrk%3D 9163553
    • Abrahamsen GC, Carr KD (1997) Effect of adrenalectomy on cocaine facilitation of lateral hypothalamic self-stimulation. Brain Res 755:156-161
    • (1997) Brain Res , vol.755 , pp. 156-161
    • Abrahamsen, G.C.1    Carr, K.D.2
  • 2
    • 0030778096 scopus 로고    scopus 로고
    • Aminoglutethimide, a corticosteroid synthesis inhibitor, facilitates brain stimulation reward in food-restricted rats: An investigation of underlying mechanisms
    • 1:CAS:528:DyaK2sXmvVyjt7w%3D
    • Abrahamsen GC, Kandawire MJ, Carr KD (1997) A}inoglutethimide, a corticosteroyd synthesis inhibitor, facilitates brain stimulation reward in vood-restricted rats: an investiwation of underlying mechanisms.0Psychopharmacology (Berlin) 133:405-412
    • (1997) Psychopharmacology (Berlin) , vol.133 , pp. 405-412
    • Abrahamsen, G.C.1    Kandawire, M.J.2    Carr, K.D.3
  • 3
    • 22744433147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclqse-activating polypeptide (PACAP) mimics neuroendocrine and behqvioral manifestations of stress: Evidence for PKA-mediated exprussion of the corticotropin-releasing hormone (CRH) gene
    • 1950324 1:CAS:528:DC%2BD2MXmvVCqtrs%3D 15882914
    • Agarwal A, Halvorson LM, Legradi G (2005) Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene. Brain Res Mol Brain Res 138:45-57
    • (2005) Brain Res Mol Brain Res , vol.138 , pp. 45-57
    • Agarwql, A.1    Halvorson, L.M.2    Legradi, G.3
  • 4
    • 0003472502 scopus 로고    scopus 로고
    • American Psychiatric Association American Psychiatric Association Washington, DC etc. pp Online resource (XLIV, 947 p.)
    • American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, DSM-5. American Psychiatric Association, Washington, DC, etc., pp Online resource (XLIV, 947 p.)
    • (2013) Diagnostic and Statistical Manual of Mental Disorders, DSM-5
  • 5
    • 0027374753 scopus 로고
    • Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats
    • 1:CAS:528:DyaK3sXhs1WgtLY%3D 8093731
    • Bals-Kubik R, Ableitner A, Herz A, Shippenberg TS (1993) Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats. J Pharmacol Exp Ther 264:489-495
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 489-495
    • Bals-Kubik, R.1    Ableitner, A.2    Herz, A.3    Shippenberg, T.S.4
  • 6
    • 0034285026 scopus 로고    scopus 로고
    • Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats
    • 1:CAS:528:DC%2BD3cXmtVCrtr0%3D 10967316
    • Barr AM, Brotto LA, Phillips AG (2000) Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats. Brain Res 875:196-201
    • (2000) Brain Res , vol.875 , pp. 196-201
    • Barr, A.M.1    Brotto, L.A.2    Phillips, A.G.3
  • 7
    • 56449104205 scopus 로고    scopus 로고
    • Repeated social defeat-induced depression-like behavioral and biological alterations in rats: Involvement of cholecystokinin
    • 1:CAS:528:DC%2BD1cXhtlOjtr7J 17893702
    • Becker C, Zeau B, Rivat C, Blugeot A, Hamon M, Benoliel JJ (2008) Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin. Mol Psychiatry 13:1079-1092
    • (2008) Mol Psychiatry , vol.13 , pp. 1079-1092
    • Becker, C.1    Zeau, B.2    Rivat, C.3    Blugeot, A.4    Hamon, M.5    Benoliel, J.J.6
  • 9
    • 84881585924 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide 6-38 blocks cocaine- and amphetamine-regulated transcript peptide-induced hypophagia in rats
    • 3744533 1:CAS:528:DC%2BC3sXhtlGjtL3J 23967296
    • Burgos JR, Iresjo BM, Smedh U (2013) Pituitary adenylate cyclase-activating polypeptide 6-38 blocks cocaine- and amphetamine-regulated transcript peptide-induced hypophagia in rats. PLoS One 8:e72347
    • (2013) PLoS One , vol.8 , pp. e72347
    • Burgos, J.R.1    Iresjo, B.M.2    Smedh, U.3
  • 10
    • 0034724983 scopus 로고    scopus 로고
    • Hypoinsulinemia may mediate the lowering of self-stimulation thresholds by food restriction and streptozotocin-induced diabetes
    • 1:CAS:528:DC%2BD3cXisFGmsbg%3D 10773204
    • Carr KD, Kim G, Cabeza de Vaca S (2000) Hypoinsulinemia may mediate the lowering of self-stimulation thresholds by food restriction and streptozotocin-induced diabetes. Brain Res 863:160-168
    • (2000) Brain Res , vol.863 , pp. 160-168
    • Carr, K.D.1    Kim, G.2    Cabeza De Vaca, S.3
  • 12
    • 19944418868 scopus 로고    scopus 로고
    • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
    • 1:CAS:528:DC%2BD2MXltFWlurg%3D 15893822
    • Cryan JF, Valentino RJ, Lucki I (2005) Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev 29:547-569
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 547-569
    • Cryan, J.F.1    Valentino, R.J.2    Lucki, I.3
  • 13
    • 84922634091 scopus 로고    scopus 로고
    • Enduring deficits in brain reward function after chronic social defeat in rats: Susceptibility, resilience, and antidepressant response
    • 1:CAS:528:DC%2BC2cXjsVKrs7s%3D 24576687
    • Der-Avakian A, Mazei-Robison MS, Kesby JP, Nestler EJ, Markou A (2014) Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response. Biol Psychiatry 76:542-549
    • (2014) Biol Psychiatry , vol.76 , pp. 542-549
    • Der-Avakian, A.1    Mazei-Robison, M.S.2    Kesby, J.P.3    Nestler, E.J.4    Markou, A.5
  • 14
    • 13344249761 scopus 로고    scopus 로고
    • Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: The effects of water depth
    • 1:STN:280:DyaK28zotVClsA%3D%3D 8788475
    • Detke MJ, Lucki I (1996) Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth. Behav Brain Res 73:43-46
    • (1996) Behav Brain Res , vol.73 , pp. 43-46
    • Detke, M.J.1    Lucki, I.2
  • 15
    • 0030987218 scopus 로고    scopus 로고
    • Evidence for roles of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) receptors in modulating the responses of rat dorsal horn neurons to sensory inputs
    • 1:CAS:528:DyaK2sXjsFahtrk%3D 9179871
    • Dickinson T, Fleetwood-Walker SM, Mitchell R, Lutz EM (1997) Evidence for roles of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) receptors in modulating the responses of rat dorsal horn neurons to sensory inputs. Neuropeptides 31:175-185
    • (1997) Neuropeptides , vol.31 , pp. 175-185
    • Dickinson, T.1    Fleetwood-Walker, S.M.2    Mitchell, R.3    Lutz, E.M.4
  • 16
    • 84883304089 scopus 로고    scopus 로고
    • CRF mediates the anxiogenic and anti-rewarding, but not the anorectic effects of PACAP
    • 3773665 1:CAS:528:DC%2BC3sXhsVCqur%2FE 23657440
    • Dore R, Iemolo A, Smith KL, Wang X, Cottone P, Sabino V (2013) CRF mediates the anxiogenic and anti-rewarding, but not the anorectic effects of PACAP. Neuropsychopharmacology 38:2160-2169
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2160-2169
    • Dore, R.1    Iemolo, A.2    Smith, K.L.3    Wang, X.4    Cottone, P.5    Sabino, V.6
  • 17
    • 79952117803 scopus 로고    scopus 로고
    • Neural substrates of psychostimulant withdrawal-induced anhedonia
    • 21161752
    • D'Souza MS, Markou A (2010) Neural substrates of psychostimulant withdrawal-induced anhedonia. Curr Top Behav Neurosci 3:119-178
    • (2010) Curr Top Behav Neurosci , vol.3 , pp. 119-178
    • D'Souza, M.S.1    Markou, A.2
  • 18
    • 0023267832 scopus 로고
    • Corticotropin-releasing factor has an anxiogenic action in the social interaction test
    • 1:CAS:528:DyaL2sXkslWit74%3D 2886414
    • Dunn AJ, File SE (1987) Corticotropin-releasing factor has an anxiogenic action in the social interaction test. Horm Behav 21:193-202
    • (1987) Horm Behav , vol.21 , pp. 193-202
    • Dunn, A.J.1    File, S.E.2
  • 19
    • 0037470195 scopus 로고    scopus 로고
    • A review of 25 years of the social interaction test
    • 1:CAS:528:DC%2BD3sXhsVanu7o%3D 12600701
    • File SE, Seth P (2003) A review of 25 years of the social interaction test. Eur J Pharmacol 463:35-53
    • (2003) Eur J Pharmacol , vol.463 , pp. 35-53
    • File, S.E.1    Seth, P.2
  • 20
    • 0016724261 scopus 로고
    • Effects of d- versus l-amphetamine, food deprivation, and current intensity on self-stimulation of the lateral hypothalamus, substantia nigra, and medial frontal cortex of the rat
    • 1:CAS:528:DyaE28XlsVajsQ%3D%3D 1202097
    • Goodall EB, Carey RJ (1975) Effects of d- versus l-amphetamine, food deprivation, and current intensity on self-stimulation of the lateral hypothalamus, substantia nigra, and medial frontal cortex of the rat. J Comp Physiol Psychol 89:1029-1045
    • (1975) J Comp Physiol Psychol , vol.89 , pp. 1029-1045
    • Goodall, E.B.1    Carey, R.J.2
  • 21
    • 0026450933 scopus 로고
    • The effects of cortisol infusion upon hormone secretion from the anterior pituitary and subjective mood in depressive illness and in controls
    • 1:STN:280:DyaK3s%2Fnslymsw%3D%3D 1332993
    • Goodwin GM, Muir WJ, Seckl JR, Bennie J, Carroll S, Dick H, Fink G (1992) The effects of cortisol infusion upon hormone secretion from the anterior pituitary and subjective mood in depressive illness and in controls. J Affect Disord 26:73-83
    • (1992) J Affect Disord , vol.26 , pp. 73-83
    • Goodwin, G.M.1    Muir, W.J.2    Seckl, J.R.3    Bennie, J.4    Carroll, S.5    Dick, H.6    Fink, G.7
  • 22
    • 84937786412 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide in stress-related disorders: Data convergence from animal and human studies
    • Hammack SE, May V (2014) Pituitary adenylate cyclase activating polypeptide in stress-related disorders: data convergence from animal and human studies. Biol Psychiatry
    • (2014) Biol Psychiatry
    • Hammack, S.E.1
  • 26
    • 84867594179 scopus 로고    scopus 로고
    • Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice
    • 3462416 1:CAS:528:DC%2BC3sXht1ajur3O 23060763
    • Hattori S, Takao K, Tanda K, Toyama K, Shintani N, Baba A, Hashimoto H, Miyakawa T (2012) Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice. Front Behav Neurosci 6:58
    • (2012) Front Behav Neurosci , vol.6 , pp. 58
    • Hattori, S.1    Takao, K.2    Tanda, K.3    Toyama, K.4    Shintani, N.5    Baba, A.6    Hashimoto, H.7    Miyakawa, T.8
  • 28
    • 0026688974 scopus 로고
    • Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action
    • 1:CAS:528:DyaK38Xks1egsL4%3D 1327398
    • Heinrichs SC, Pich EM, Miczek KA, Britton KT, Koob GF (1992) Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action. Brain Res 581:190-197
    • (1992) Brain Res , vol.581 , pp. 190-197
    • Heinrichs, S.C.1    Pich, E.M.2    Miczek, K.A.3    Britton, K.T.4    Koob, G.F.5
  • 29
    • 0242352560 scopus 로고    scopus 로고
    • Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders
    • 1:CAS:528:DC%2BD3sXos12ks7o%3D 14607081
    • Holmes A, Heilig M, Rupniak NM, Steckler T, Griebel G (2003) Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders. Trends Pharmacol Sci 24:580-588
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 580-588
    • Holmes, A.1    Heilig, M.2    Rupniak, N.M.3    Steckler, T.4    Griebel, G.5
  • 30
    • 84864872016 scopus 로고    scopus 로고
    • Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats
    • 3934429 22854309
    • Iemolo A, Valenza M, Tozier L, Knapp CM, Kornetsky C, Steardo L, Sabino V, Cottone P (2012) Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats. Behav Pharmacol 23:593-602
    • (2012) Behav Pharmacol , vol.23 , pp. 593-602
    • Iemolo, A.1    Valenza, M.2    Tozier, L.3    Knapp, C.M.4    Kornetsky, C.5    Steardo, L.6    Sabino, V.7    Cottone, P.8
  • 31
    • 84930818874 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide in the central amygdala causes anorexia and body weight loss via the melanocortin and the TrkB systems
    • Iemolo A, Ferragud A, Cottone P, Sabino V (2015) Pituitary adenylate cyclase-activating peptide in the central amygdala causes anorexia and body weight loss via the melanocortin and the TrkB systems. Neuropsychopharmacology
    • (2015) Neuropsychopharmacology
    • Iemolo, A.1    Ferragud, A.2    Cottone, P.3
  • 32
    • 84907205472 scopus 로고    scopus 로고
    • Modulatory effect of VIP injected into hippocampal CA1 area on anxiety in olfactory bulbectomized rats
    • Ivanova M, Belcheva S, Belcheva I, Stoyanov Z, Tashev R (2014) Modulatory effect of VIP injected into hippocampal CA1 area on anxiety in olfactory bulbectomized rats. Acta Neurobiol Exp 74:317-327
    • (2014) Acta Neurobiol Exp , vol.74 , pp. 317-327
    • Ivanova, M.1    Belcheva, S.2    Belcheva, I.3    Stoyanov, Z.4    Tashev, R.5
  • 33
    • 3543077645 scopus 로고    scopus 로고
    • Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain
    • 1:CAS:528:DC%2BD2cXnt1emsrs%3D 15282712
    • Joo KM, Chung YH, Kim MK, Nam RH, Lee BL, Lee KH, Cha CI (2004) Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain. J Comp Neurol 476:388-413
    • (2004) J Comp Neurol , vol.476 , pp. 388-413
    • Joo, K.M.1    Chung, Y.H.2    Kim, M.K.3    Nam, R.H.4    Lee, B.L.5    Lee, K.H.6    Cha, C.I.7
  • 34
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R)
    • National Comorbidity Survey R 12813115
    • Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS, National Comorbidity Survey R (2003) The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 289:3095-3105
    • (2003) JAMA , vol.289 , pp. 3095-3105
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Koretz, D.5    Merikangas, K.R.6    Rush, A.J.7    Walters, E.E.8    Wang, P.S.9
  • 35
    • 84904887593 scopus 로고    scopus 로고
    • Pair bond formation is impaired by VPAC receptor antagonism in the socially monogamous zebra finch
    • 1:CAS:528:DC%2BC2cXhtlejtbbL 25014003
    • Kingsbury MA, Goodson JL (2014) Pair bond formation is impaired by VPAC receptor antagonism in the socially monogamous zebra finch. Behav Brain Res 272:264-268
    • (2014) Behav Brain Res , vol.272 , pp. 264-268
    • Kingsbury, M.A.1    Goodson, J.L.2
  • 36
    • 75149118146 scopus 로고    scopus 로고
    • Dynorphin, stress, and depression
    • 1:CAS:528:DC%2BC3cXhtlelsLw%3D 19782055
    • Knoll AT, Carlezon WA Jr (2010) Dynorphin, stress, and depression. Brain Res 1314:56-73
    • (2010) Brain Res , vol.1314 , pp. 56-73
    • Knoll, A.T.1    Carlezon, W.A.2
  • 38
    • 0018698752 scopus 로고
    • Euphorigenic drugs: Effects on the reward pathways of the brain
    • 1:CAS:528:DyaL3cXhsV2gtg%3D%3D 488370
    • Kornetsky C, Esposito RU (1979) Euphorigenic drugs: effects on the reward pathways of the brain. Fed Proc 38:2473-2476
    • (1979) Fed Proc , vol.38 , pp. 2473-2476
    • Kornetsky, C.1    Esposito, R.U.2
  • 40
    • 38349031157 scopus 로고    scopus 로고
    • The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system
    • 1:CAS:528:DC%2BD1cXovVGisQ%3D%3D
    • Land BB, Bruchas MR, Lemos JC, Xu M, Melief EJ, Chavkin C (2008) The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system. J Neurosci: Off J Soc Neurosci 28:407-414
    • (2008) J Neurosci: Off J Soc Neurosci , vol.28 , pp. 407-414
    • Land, B.B.1    Bruchas, M.R.2    Lemos, J.C.3    Xu, M.4    Melief, E.J.5    Chavkin, C.6
  • 41
    • 84885029743 scopus 로고    scopus 로고
    • PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress
    • Lehmann ML, Mustafa T, Eiden AM, Herkenham M, Eiden LE (2012) PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress. Psychoneuroendocrinology
    • (2012) Psychoneuroendocrinology
    • Lehmann, M.L.1    Mustafa, T.2    Eiden, A.M.3    Herkenham, M.4    Eiden, L.E.5
  • 42
    • 80052748268 scopus 로고    scopus 로고
    • The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice
    • 3176581 1:CAS:528:DC%2BC3MXhtFyms7nL 21677650
    • Lukas M, Toth I, Reber SO, Slattery DA, Veenema AH, Neumann ID (2011) The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice. Neuropsychopharmacology 36:2159-2168
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2159-2168
    • Lukas, M.1    Toth, I.2    Reber, S.O.3    Slattery, D.A.4    Veenema, A.H.5    Neumann, I.D.6
  • 43
    • 0034595891 scopus 로고    scopus 로고
    • CRF and urocortin decreased brain stimulation reward in the rat: Reversal by a CRF receptor antagonist
    • 1:CAS:528:DC%2BD3cXjsVGisrY%3D 10825483
    • Macey DJ, Koob GF, Markou A (2000) CRF and urocortin decreased brain stimulation reward in the rat: reversal by a CRF receptor antagonist. Brain Res 866:82-91
    • (2000) Brain Res , vol.866 , pp. 82-91
    • Macey, D.J.1    Koob, G.F.2    Markou, A.3
  • 44
    • 0026092779 scopus 로고
    • Postcocaine anhedonia. An animal model of cocaine withdrawal
    • 1:CAS:528:DyaK3MXksVWktrs%3D 2003866
    • Markou A, Koob GF (1991) Postcocaine anhedonia. An animal model of cocaine withdrawal. Neuropsychopharmacology 4:17-26
    • (1991) Neuropsychopharmacology , vol.4 , pp. 17-26
    • Markou, A.1    Koob, G.F.2
  • 45
    • 0026503778 scopus 로고
    • Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations
    • 1:STN:280:DyaK387lvFagsg%3D%3D 1741436
    • Markou A, Koob GF (1992) Construct validity of a self-stimulation threshold paradigm: effects of reward and performance manipulations. Physiol Behav 51:111-119
    • (1992) Physiol Behav , vol.51 , pp. 111-119
    • Markou, A.1    Koob, G.F.2
  • 46
    • 0026463436 scopus 로고
    • Desmethylimipramine attenuates cocaine withdrawal in rats
    • 1:CAS:528:DyaK3sXit1Gmt74%3D
    • Markou A, Hauger RL, Koob GF (1992) Desmethylimipramine attenuates cocaine withdrawal in rats. Psychopharmacology (Berlin) 109:305-314
    • (1992) Psychopharmacology (Berlin) , vol.109 , pp. 305-314
    • Markou, A.1    Hauger, R.L.2    Koob, G.F.3
  • 47
    • 0028898567 scopus 로고
    • Comorbidity and social phobia: Evidence from clinical, epidemiologic, and genetic studies
    • 1:STN:280:DyaK2M3ptVGjtQ%3D%3D 7772612
    • Merikangas KR, Angst J (1995) Comorbidity and social phobia: evidence from clinical, epidemiologic, and genetic studies. Eur Arch Psychiatry Clin Neurosci 244:297-303
    • (1995) Eur Arch Psychiatry Clin Neurosci , vol.244 , pp. 297-303
    • Merikangas, K.R.1    Angst, J.2
  • 48
    • 84904558273 scopus 로고    scopus 로고
    • Parabrachial nucleus (PBn) pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the amygdala: Implication for the sensory and behavioral effects of pain
    • 1:CAS:528:DC%2BC2cXht1Oqs7fK 24998751
    • Missig G, Roman CW, Vizzard MA, Braas KM, Hammack SE, May V (2014) Parabrachial nucleus (PBn) pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the amygdala: implication for the sensory and behavioral effects of pain. Neuropharmacology 86:38-48
    • (2014) Neuropharmacology , vol.86 , pp. 38-48
    • Missig, G.1    Roman, C.W.2    Vizzard, M.A.3    Braas, K.M.4    Hammack, S.E.5    May, V.6
  • 49
    • 0028895195 scopus 로고
    • Chronic mild stress-induced anhedonia model of depression; Sleep abnormalities and curative effects of electroshock treatment
    • 11224370
    • Moreau JL, Scherschlicht R, Jenck F, Martin JR (1995) Chronic mild stress-induced anhedonia model of depression; sleep abnormalities and curative effects of electroshock treatment. Behav Pharmacol 6:682-687
    • (1995) Behav Pharmacol , vol.6 , pp. 682-687
    • Moreau, J.L.1    Scherschlicht, R.2    Jenck, F.3    Martin, J.R.4
  • 50
    • 0027055174 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) reduces food intake in mice
    • 1:CAS:528:DyaK3sXpsVKqtQ%3D%3D 1494495
    • Morley JE, Horowitz M, Morley PM, Flood JF (1992) Pituitary adenylate cyclase activating polypeptide (PACAP) reduces food intake in mice. Peptides 13:1133-1135
    • (1992) Peptides , vol.13 , pp. 1133-1135
    • Morley, J.E.1    Horowitz, M.2    Morley, P.M.3    Flood, J.F.4
  • 52
    • 84942504791 scopus 로고    scopus 로고
    • Impact of PACAP and PAC1 receptor deficiency on the neurochemical and behavioral effects of acute and chronic restraint stress in male C57BL/6 mice
    • Mustafa T, Jiang SZ, Eiden AM, Weihe E, Thistlethwaite I, Eiden LE (2015) Impact of PACAP and PAC1 receptor deficiency on the neurochemical and behavioral effects of acute and chronic restraint stress in male C57BL/6 mice. Stress: 1-11
    • (2015) Stress , pp. 1-11
    • Mustafa, T.1    Jiang, S.Z.2    Eiden, A.M.3    Weihe, E.4    Thistlethwaite, I.5    Eiden, L.E.6
  • 53
    • 13844298071 scopus 로고    scopus 로고
    • Behavioral effects of local microinfusion of pituitary adenylate cyclase activating polypeptide (PACAP) into the paraventricular nucleus of the hypothalamus (PVN)
    • 1950325 1:CAS:528:DC%2BD2MXhsVOguro%3D 15721485
    • Norrholm SD, Das M, Legradi G (2005) Behavioral effects of local microinfusion of pituitary adenylate cyclase activating polypeptide (PACAP) into the paraventricular nucleus of the hypothalamus (PVN). Regul Pept 128:33-41
    • (2005) Regul Pept , vol.128 , pp. 33-41
    • Norrholm, S.D.1    Das, M.2    Legradi, G.3
  • 55
    • 0022494591 scopus 로고
    • Psychotomimesis mediated by kappa opiate receptors
    • 1:CAS:528:DyaL28XltVynt7g%3D 3016896
    • Pfeiffer A, Brantl V, Herz A, Emrich HM (1986) Psychotomimesis mediated by kappa opiate receptors. Science 233:774-776
    • (1986) Science , vol.233 , pp. 774-776
    • Pfeiffer, A.1    Brantl, V.2    Herz, A.3    Emrich, H.M.4
  • 56
    • 0029807660 scopus 로고    scopus 로고
    • Distribution of pituitary adenylate cyclase activating polypeptide (PACAP) immunoreactivity in the hypothalamus and extended amygdala of the rat
    • 1:CAS:528:DyaK28Xns1egsL8%3D 8951643
    • Piggins HD, Stamp JA, Burns J, Rusak B, Semba K (1996) Distribution of pituitary adenylate cyclase activating polypeptide (PACAP) immunoreactivity in the hypothalamus and extended amygdala of the rat. J Comp Neurol 376:278-294
    • (1996) J Comp Neurol , vol.376 , pp. 278-294
    • Piggins, H.D.1    Stamp, J.A.2    Burns, J.3    Rusak, B.4    Semba, K.5
  • 57
    • 0018268297 scopus 로고
    • Behavioural despair in rats: A new model sensitive to antidepressant treatments
    • 1:CAS:528:DyaE1cXhvVagsr0%3D 204499
    • Porsolt RD, Anton G, Blavet N, Jalfre M (1978) Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 47:379-391
    • (1978) Eur J Pharmacol , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 58
    • 82755192274 scopus 로고    scopus 로고
    • Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesis
    • 1:CAS:528:DC%2BC38XhtFWkuw%3D%3D
    • Resch JM, Boisvert JP, Hourigan AE, Mueller CR, Yi SS, Choi S (2011) Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesis. Am J Physiol Regul, Integr Comp Physiol 301:R1625-R1634
    • (2011) Am J Physiol Regul, Integr Comp Physiol , vol.301 , pp. R1625-R1634
    • Resch, J.M.1    Boisvert, J.P.2    Hourigan, A.E.3    Mueller, C.R.4    Yi, S.S.5    Choi, S.6
  • 59
    • 84903748405 scopus 로고    scopus 로고
    • PAC1 receptor antagonism in the bed nucleus of the stria terminalis (BNST) attenuates the endocrine and behavioral consequences of chronic stress
    • 4342758 1:CAS:528:DC%2BC2cXhtFSls7nK 25001965
    • Roman CW, Lezak KR, Hartsock MJ, Falls WA, Braas KM, Howard AB, Hammack SE, May V (2014) PAC1 receptor antagonism in the bed nucleus of the stria terminalis (BNST) attenuates the endocrine and behavioral consequences of chronic stress. Psychoneuroendocrinology 47:151-165
    • (2014) Psychoneuroendocrinology , vol.47 , pp. 151-165
    • Roman, C.W.1    Lezak, K.R.2    Hartsock, M.J.3    Falls, W.A.4    Braas, K.M.5    Howard, A.B.6    Hammack, S.E.7    May, V.8
  • 60
    • 34249869543 scopus 로고    scopus 로고
    • 14-Methoxymetopon, a highly potent mu opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats
    • 1:CAS:528:DC%2BD2sXmtVGju7s%3D
    • Sabino V, Cottone P, Steardo L, Schmidhammer H, Zorrilla EP (2007) 14-Methoxymetopon, a highly potent mu opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats. Psychopharmacology (Berlin) 192:537-546
    • (2007) Psychopharmacology (Berlin) , vol.192 , pp. 537-546
    • Sabino, V.1    Cottone, P.2    Steardo, L.3    Schmidhammer, H.4    Zorrilla, E.P.5
  • 61
    • 0025744335 scopus 로고
    • Reversal of antidepressant action by dopamine antagonists in an animal model of depression
    • 1:CAS:528:DyaK3MXlsFSgsLo%3D
    • Sampson D, Willner P, Muscat R (1991) Reversal of antidepressant action by dopamine antagonists in an animal model of depression. Psychopharmacology (Berlin) 104:491-495
    • (1991) Psychopharmacology (Berlin) , vol.104 , pp. 491-495
    • Sampson, D.1    Willner, P.2    Muscat, R.3
  • 62
    • 0029014032 scopus 로고
    • Decreased brain reward produced by ethanol withdrawal
    • 41605 1:CAS:528:DyaK2MXmsFWqt7s%3D 7597046
    • Schulteis G, Markou A, Cole M, Koob GF (1995) Decreased brain reward produced by ethanol withdrawal. Proc Natl Acad Sci U S A 92:5880-5884
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5880-5884
    • Schulteis, G.1    Markou, A.2    Cole, M.3    Koob, G.F.4
  • 63
    • 0013832650 scopus 로고
    • Influence of adrenal steroids on self-stimulation rates in rats
    • 1:CAS:528:DyaF28XltlGksQ%3D%3D
    • Slusher MA (1965) Influence of adrenal steroids on self-stimulation rates in rats. Proc Soc Exp Biol Med Soc Exp Biol Med 120:617-620
    • (1965) Proc Soc Exp Biol Med Soc Exp Biol Med , vol.120 , pp. 617-620
    • Slusher, M.A.1
  • 64
    • 84920897057 scopus 로고    scopus 로고
    • Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats
    • 1:CAS:528:DC%2BC2MXhtlWiu7s%3D 25543171
    • Telegdy G, Adamik A (2015) Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats. Behav Brain Res 281:333-338
    • (2015) Behav Brain Res , vol.281 , pp. 333-338
    • Telegdy, G.1    Adamik, A.2
  • 65
    • 0009597077 scopus 로고    scopus 로고
    • Anxiogenic effect of central CCK administration is attenuated by chronic fluoxetine or ipsapirone treatment
    • 1:CAS:528:DyaK1MXhvVOqtrc%3D 10218869
    • To CT, Bagdy G (1999) Anxiogenic effect of central CCK administration is attenuated by chronic fluoxetine or ipsapirone treatment. Neuropharmacology 38:279-282
    • (1999) Neuropharmacology , vol.38 , pp. 279-282
    • To, C.T.1    Bagdy, G.2
  • 66
    • 2442628167 scopus 로고    scopus 로고
    • Effects of kappa-opioid receptor ligands on intracranial self-stimulation in rats
    • 1:CAS:528:DC%2BD2cXis1eks7k%3D
    • Todtenkopf MS, Marcus JF, Portoghese PS, Carlezon WA Jr (2004) Effects of kappa-opioid receptor ligands on intracranial self-stimulation in rats. Psychopharmacology (Berlin) 172:463-470
    • (2004) Psychopharmacology (Berlin) , vol.172 , pp. 463-470
    • Todtenkopf, M.S.1    Marcus, J.F.2    Portoghese, P.S.3    Carlezon, W.A.4
  • 67
    • 84939268006 scopus 로고    scopus 로고
    • Diet-induced obesity and diet-resistant rats: Differences in the rewarding and anorectic effects of D-amphetamine
    • Berlin
    • Valenza M, Steardo L, Cottone P, Sabino V (2015) Diet-induced obesity and diet-resistant rats: differences in the rewarding and anorectic effects of D-amphetamine. Psychopharmacology (Berlin)
    • (2015) Psychopharmacology
    • Valenza, M.1    Steardo, L.2    Cottone, P.3
  • 69
    • 0019901851 scopus 로고
    • Models of cognitive impairment: Cognitive changes in depression
    • 1:STN:280:DyaL383nsFOmsQ%3D%3D 7111602
    • Weingartner H, Silberman E (1982) Models of cognitive impairment: cognitive changes in depression. Psychopharmacol Bull 18:27-42
    • (1982) Psychopharmacol Bull , vol.18 , pp. 27-42
    • Weingartner, H.1    Silberman, E.2
  • 70
    • 0025057433 scopus 로고
    • Animal models of depression: An overview
    • 1:CAS:528:DyaK3cXitlejtLY%3D 2405444
    • Willner P (1990) Animal models of depression: an overview. Pharmacol Ther 45:425-455
    • (1990) Pharmacol Ther , vol.45 , pp. 425-455
    • Willner, P.1
  • 71
    • 0023636527 scopus 로고
    • Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
    • 1:CAS:528:DyaL2sXmt12jtrg%3D
    • Willner P, Towell A, Sampson D, Sophokleous S, Muscat R (1987) Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berlin) 93:358-364
    • (1987) Psychopharmacology (Berlin) , vol.93 , pp. 358-364
    • Willner, P.1    Towell, A.2    Sampson, D.3    Sophokleous, S.4    Muscat, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.