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Volumn 86, Issue 10, 2012, Pages 5508-5514

The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NONSTRUCTURAL PROTEIN 1;

EID: 84861302591     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.07081-11     Document Type: Article
Times cited : (55)

References (34)
  • 1
    • 0036164518 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections
    • Alcon S, et al. 2002. Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections. J. Clin. Microbiol. 40:376 -381.
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 376-381
    • Alcon, S.1
  • 2
    • 77951063838 scopus 로고    scopus 로고
    • Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
    • Avirutnan P, et al. 2010. Antagonism of the complement component C4 by flavivirus nonstructural protein NS1. J. Exp. Med. 207:793- 806.
    • (2010) J. Exp. Med. , vol.207 , pp. 793-806
    • Avirutnan, P.1
  • 3
    • 79960404180 scopus 로고    scopus 로고
    • Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation
    • Avirutnan P, et al. 2011. Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation. J. Immunol. 187:424-433.
    • (2011) J. Immunol. , vol.187 , pp. 424-433
    • Avirutnan, P.1
  • 4
    • 33645798035 scopus 로고    scopus 로고
    • Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement
    • Avirutnan P, et al. 2006. Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J. Infect. Dis. 193:1078 -1088.
    • (2006) J. Infect. Dis. , vol.193 , pp. 1078-1088
    • Avirutnan, P.1
  • 5
    • 77649262630 scopus 로고    scopus 로고
    • Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification
    • Balsitis SJ, et al. 2010. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6:e1000790.
    • (2010) PLoS Pathog , vol.6
    • Balsitis, S.J.1
  • 6
    • 77956189846 scopus 로고    scopus 로고
    • A method for full genome sequencing of all four serotypes of the dengue virus
    • Christenbury JG, et al. 2010. A method for full genome sequencing of all four serotypes of the dengue virus. J. Virol. Methods 169:202-206.
    • (2010) J. Virol. Methods , vol.169 , pp. 202-206
    • Christenbury, J.G.1
  • 7
    • 37549069351 scopus 로고    scopus 로고
    • The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection
    • Chuansumrit A, et al. 2008. The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection. Pediatr. Infect. Dis. J. 27:43- 48.
    • (2008) Pediatr. Infect. Dis. J. , vol.27 , pp. 43-48
    • Chuansumrit, A.1
  • 8
    • 79960967477 scopus 로고    scopus 로고
    • Clinical and virological factors influencing the performance of a NS1 antigen-capture assay and potential use as a marker of dengue disease severity
    • Duong V, et al. 2011. Clinical and virological factors influencing the performance of a NS1 antigen-capture assay and potential use as a marker of dengue disease severity. PLoS Negl. Trop. Dis. 5:e1244.
    • (2011) PLoS Negl. Trop. Dis. , vol.5
    • Duong, V.1
  • 9
    • 34248672255 scopus 로고    scopus 로고
    • Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum
    • Dussart P, et al. 2006. Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum. Clin. Vaccine Immunol. 13:1185-1189.
    • (2006) Clin. Vaccine Immunol. , vol.13 , pp. 1185-1189
    • Dussart, P.1
  • 10
    • 56149086832 scopus 로고    scopus 로고
    • Evaluation of two new commercial tests for the diagnosis of acute dengue virus infection using NS1 antigen detection in human serum
    • Dussart P, et al. 2008. Evaluation of two new commercial tests for the diagnosis of acute dengue virus infection using NS1 antigen detection in human serum. PLoS Negl. Trop. Dis. 2:e280.
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Dussart, P.1
  • 11
    • 79954627419 scopus 로고    scopus 로고
    • Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status
    • Duyen HT, et al. 2011. Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status. J. Infect. Dis. 203:1292-1300.
    • (2011) J. Infect. Dis. , vol.203 , pp. 1292-1300
    • Duyen, H.T.1
  • 12
    • 0032994359 scopus 로고    scopus 로고
    • Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion
    • Flamand M, et al. 1999. Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion. J. Virol. 73:6104-6110.
    • (1999) J. Virol. , vol.73 , pp. 6104-6110
    • Flamand, M.1
  • 13
    • 78149241108 scopus 로고    scopus 로고
    • Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis
    • Guzman MG, et al. 2010. Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis. PLoS Negl. Trop. Dis. 4:e811.
    • (2010) PLoS Negl. Trop. Dis. , vol.4
    • Guzman, M.G.1
  • 14
    • 35748929379 scopus 로고    scopus 로고
    • Dengue
    • Halstead SB. 2007. Dengue. Lancet 370:1644 -1652.
    • (2007) Lancet , vol.370 , pp. 1644-1652
    • Halstead, S.B.1
  • 15
    • 0642287817 scopus 로고    scopus 로고
    • Neutralization and antibody-dependent enhancement of dengue viruses
    • Halstead SB. 2003. Neutralization and antibody-dependent enhancement of dengue viruses. Adv. Virus Res. 60:421- 467.
    • (2003) Adv. Virus Res. , vol.60 , pp. 421-467
    • Halstead, S.B.1
  • 16
    • 65549138517 scopus 로고    scopus 로고
    • Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses
    • Hang VT, et al. 2009. Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses. PLoS Negl. Trop. Dis. 3:e360.
    • (2009) PLoS Negl. Trop. Dis. , vol.3
    • Hang, V.T.1
  • 17
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
    • Harlow E, Lane D. 1988. Antibodies: a laboratory manual, p 564-565. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
    • (1988) Antibodies: a laboratory manual , pp. 564-565
    • Harlow, E.1    Lane, D.2
  • 18
    • 0032708941 scopus 로고    scopus 로고
    • Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase
    • Khromykh AA, Sedlak PL, Guyatt KJ, Hall RA, Westaway EG. 1999. Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase. J. Virol. 73:10272-10280.
    • (1999) J. Virol. , vol.73 , pp. 10272-10280
    • Khromykh, A.A.1    Sedlak, P.L.2    Guyatt, K.J.3    Hall, R.A.4    Westaway, E.G.5
  • 19
    • 33846837300 scopus 로고    scopus 로고
    • Evaluation of a commercial dengue NS1 antigen-capture ELISA for laboratory diagnosis of acute dengue virus infection
    • Kumarasamy V, et al. 2007. Evaluation of a commercial dengue NS1 antigen-capture ELISA for laboratory diagnosis of acute dengue virus infection. J. Virol. Methods 140:75-79.
    • (2007) J. Virol. Methods , vol.140 , pp. 75-79
    • Kumarasamy, V.1
  • 20
    • 40749125265 scopus 로고    scopus 로고
    • Evaluation of an NS1 antigen detection for diagnosis of acute dengue infection in patients with acute febrile illness
    • Lapphra K, et al. 2008. Evaluation of an NS1 antigen detection for diagnosis of acute dengue infection in patients with acute febrile illness. Diagn. Microbiol. Infect. Dis. 60:387-391.
    • (2008) Diagn. Microbiol. Infect. Dis. , vol.60 , pp. 387-391
    • Lapphra, K.1
  • 21
    • 0037108657 scopus 로고    scopus 로고
    • High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
    • Libraty DH, et al. 2002. High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. J. Infect. Dis. 186:1165-1168.
    • (2002) J. Infect. Dis. , vol.186 , pp. 1165-1168
    • Libraty, D.H.1
  • 22
    • 33846024047 scopus 로고    scopus 로고
    • Early Dengue infection and outcome study (EDEN)-study design and preliminary findings
    • Low JG, et al. 2006. Early Dengue infection and outcome study (EDEN)-study design and preliminary findings. Ann. Acad. Med. Singapore 35:783-789.
    • (2006) Ann. Acad. Med. Singapore , vol.35 , pp. 783-789
    • Low, J.G.1
  • 23
    • 0029941322 scopus 로고    scopus 로고
    • Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication
    • Mackenzie JM, Jones MK, Young PR. 1996. Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication. Virology 220:232-240.
    • (1996) Virology , vol.220 , pp. 232-240
    • Mackenzie, J.M.1    Jones, M.K.2    Young, P.R.3
  • 24
    • 0005311717 scopus 로고
    • Relationship of a dengue 2 isolate from Townsville, 1993, to international isolates
    • McBride WJH, Vasudevan SG. 1995. Relationship of a dengue 2 isolate from Townsville, 1993, to international isolates. Commun. Dis. Intell. 19:522-523.
    • (1995) Commun. Dis. Intell. , vol.19 , pp. 522-523
    • McBride, W.J.H.1    Vasudevan, S.G.2
  • 25
    • 79955663893 scopus 로고    scopus 로고
    • Unfolded protein response (UPR) gene expression during antibodydependent enhanced infection of cultured monocytes correlates with dengue disease severity
    • Paradkar PN, Ooi EE, Hanson BJ, Gubler DJ, Vasudevan SG. 2011. Unfolded protein response (UPR) gene expression during antibodydependent enhanced infection of cultured monocytes correlates with dengue disease severity. Biosci. Rep. 31:221-230.
    • (2011) Biosci. Rep. , vol.31 , pp. 221-230
    • Paradkar, P.N.1    Ooi, E.E.2    Hanson, B.J.3    Gubler, D.J.4    Vasudevan, S.G.5
  • 26
    • 84858740484 scopus 로고    scopus 로고
    • Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model
    • Rathore AP, et al. 2011. Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model. Antiviral Res. 92:453- 460.
    • (2011) Antiviral Res , vol.92 , pp. 453-460
    • Rathore, A.P.1
  • 27
    • 84857251011 scopus 로고    scopus 로고
    • Expression and immunoaffinity purification of recombinant dengue virus 2 NS1 protein as a cleavable SUMOstar fusion
    • Rozen-Gagnon K, Moreland NJ, Ruedl C, Vasudevan SG. 2012. Expression and immunoaffinity purification of recombinant dengue virus 2 NS1 protein as a cleavable SUMOstar fusion. Protein Expr. Purif. 82:20 -25.
    • (2012) Protein Expr. Purif. , vol.82 , pp. 20-25
    • Rozen-Gagnon, K.1    Moreland, N.J.2    Ruedl, C.3    Vasudevan, S.G.4
  • 28
    • 33847042742 scopus 로고    scopus 로고
    • A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs
    • Schul W, Liu W, Xu HY, Flamand M, Vasudevan SG. 2007. A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs. J. Infect. Dis. 195:665- 674.
    • (2007) J. Infect. Dis. , vol.195 , pp. 665-674
    • Schul, W.1    Liu, W.2    Xu, H.Y.3    Flamand, M.4    Vasudevan, S.G.5
  • 29
    • 77952380265 scopus 로고    scopus 로고
    • A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice
    • Tan GK, et al. 2010. A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice. PLoS Negl. Trop. Dis. 4:e672.
    • (2010) PLoS Negl. Trop. Dis. , vol.4
    • Tan, G.K.1
  • 30
    • 80053456982 scopus 로고    scopus 로고
    • Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue
    • Tricou V, Minh NN, Farrar J, Tran HT, Simmons CP. 2011. Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue. PLoS Negl. Trop. Dis. 5:e1309.
    • (2011) PLoS Negl. Trop. Dis. , vol.5
    • Tricou, V.1    Minh, N.N.2    Farrar, J.3    Tran, H.T.4    Simmons, C.P.5
  • 31
    • 50149084681 scopus 로고    scopus 로고
    • West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction
    • Wilson JR, de Sessions PF, Leon MA, Scholle F. 2008. West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction. J. Virol. 82: 8262-8271.
    • (2008) J. Virol , vol.82 , pp. 8262-8271
    • Wilson, J.R.1    de Sessions, P.F.2    Leon, M.A.3    Scholle, F.4
  • 32
    • 0024345888 scopus 로고
    • Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization
    • Winkler G, Maxwell SE, Ruemmler C, Stollar V. 1989. Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization. Virology 171:302-305.
    • (1989) Virology , vol.171 , pp. 302-305
    • Winkler, G.1    Maxwell, S.E.2    Ruemmler, C.3    Stollar, V.4
  • 33
    • 0034088137 scopus 로고    scopus 로고
    • An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients
    • Young PR, Hilditch PA, Bletchly C, Halloran W. 2000. An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients. J. Clin. Microbiol. 38:1053-1057.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 1053-1057
    • Young, P.R.1    Hilditch, P.A.2    Bletchly, C.3    Halloran, W.4
  • 34
    • 76249103868 scopus 로고    scopus 로고
    • Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease
    • Zellweger RM, Prestwood TR, Shresta S. 2010. Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease. Cell Host Microbe 7:128-139.
    • (2010) Cell Host Microbe , vol.7 , pp. 128-139
    • Zellweger, R.M.1    Prestwood, T.R.2    Shresta, S.3


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