Catalytic Kinetic Resolution of Disubstituted Piperidines by Enantioselective Acylation: Synthetic Utility and Mechanistic Insights

Journal of the American Chemical Society

Volumn 137, Issue 35, 2015, Pages 11491-11497

  Wanner, Benedikt ^a   Kreituss, Imants ^a   Gutierrez, Osvaldo ^b   Kozlowski, Marisa C ^b   Bode, Jeffrey W ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; AMINES; ISOMERS; ORGANIC COMPOUNDS;

COMPUTATIONAL STUDIES; CONFORMATIONAL EFFECT; ENANTIOSELECTIVE ACYLATION; KINETIC RESOLUTION; N-HETEROCYCLIC CARBENES; SELECTIVITY FACTORS; SYNTHETIC UTILITY; TRANSITION STATE MODELING;

KINETICS;

HYDROXAMIC ACID; PIPERIDINE DERIVATIVE; AMINE; CARBENE; HETEROCYCLIC COMPOUND; METHANE;

ACYLATION; ARTICLE; CATALYST; CHEMICAL REACTION KINETICS; CHIRALITY; CONFORMATION; CONFORMATIONAL TRANSITION; DENSITY FUNCTIONAL THEORY; ENANTIOSELECTIVITY; KINETIC PARAMETERS; STEREOISOMERISM; STOICHIOMETRY; SYNTHESIS; ANALOGS AND DERIVATIVES; CATALYSIS; CHEMISTRY; KINETICS; MOLECULAR MODEL;

ACYLATION; AMINES; CATALYSIS; HETEROCYCLIC COMPOUNDS; HYDROXAMIC ACIDS; KINETICS; METHANE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STEREOISOMERISM;

EID: 84941242163     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b07201     Document Type: Article

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