Proton donor acidity controls selectivity in nonaromatic nitrogen heterocycle synthesis

Science

Volumn 339, Issue 6120, 2013, Pages 678-682

  Duttwyler, Simon ^a   Chen, Shuming ^a   Takase, Michael K ^a   Wiberg, Kenneth B ^a   Bergman, Robert G ^b   Ellman, Jonathan A ^a  

^a YALE UNIVERSITY   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROPYRIDINE DERIVATIVE; NUCLEOPHILE; PIPERIDINE DERIVATIVE; PROTON; RHODIUM; TADALAFIL;

CARBON; DRUG; DRUG DEVELOPMENT; HYDROGEN; NITROGEN; RHODIUM;

ACIDITY; ARTICLE; DENSITY FUNCTIONAL THEORY; HYDROGEN BOND; ISOMERIZATION; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTON TRANSPORT; REACTOR CASCADE; THERMODYNAMICS; X RAY;

EID: 84873509255     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1230704     Document Type: Article

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