Androgen receptor promotes abdominal aortic aneurysm development via modulating inflammatory interleukin-1α and transforming growth factor-β1 expression

Hypertension

Volumn 66, Issue 4, 2015, Pages 881-891

  Huang, Chiung Kuei ^a   Luo, Jie ^a   Lai, Kuo Pao ^a,b   Wang, Ronghao ^a   Pang, Haiyan ^a   Chang, Eugene ^a,c   Yan, Chen ^a   Sparks, Janet ^a   Lee, Soo Ok ^a   Cho, Joshua ^a   Chang, Chawnshang ^a,b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

androgen receptors; angiotensin II; apolipoproteins; interleukin 1 ; transforming growth factor 1

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; ANGIOTENSIN II; APOLIPOPROTEIN E; ASC J9; CARBON TETRACHLORIDE; COLLAGEN; GELATINASE A; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 1ALPHA; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; SELECTIVE ANDROGEN RECEPTOR MODULATOR; TESTOSTERONE; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; IL1A PROTEIN, HUMAN; RNA;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; AORTA DISSECTION; AORTIC TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ELASTIC FIBER; ENDOTHELIUM CELL; ENZYME MECHANISM; GENE EXPRESSION; IN VIVO STUDY; INCIDENCE; INFLAMMATION; KNOCKOUT MOUSE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN TARGETING; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DISEASE MODEL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; AORTIC ANEURYSM, ABDOMINAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; INFLAMMATION; INTERLEUKIN-1ALPHA; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RECEPTORS, ANDROGEN; RNA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84941215708     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.05654     Document Type: Article

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