-
1
-
-
0032104245
-
The extended protein kinase C superfamily
-
1:CAS:528:DyaK1cXkt1Sqs74%3D 1219479 9601053
-
Mellor H, Parker PJ (1998) The extended protein kinase C superfamily. Biochem J 332:281-292
-
(1998)
Biochem J
, vol.332
, pp. 281-292
-
-
Mellor, H.1
Parker, P.J.2
-
2
-
-
0029060391
-
Protein kinases.5. Protein-kinase-C and lipid signaling for sustained cellular-responses
-
1:CAS:528:DyaK2MXlsVOqurk%3D 7737456
-
Nishizuka Y (1995) Protein kinases.5. Protein-kinase-C and lipid signaling for sustained cellular-responses. Faseb Journal 9:484-496
-
(1995)
Faseb Journal
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
3
-
-
1542503811
-
PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation
-
1:CAS:528:DC%2BD2cXhsV2qtr8%3D 14737078
-
Jiffar T, Kurinna S, Suck G et al (2004) PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation. Leukemia 18:505-512
-
(2004)
Leukemia
, vol.18
, pp. 505-512
-
-
Jiffar, T.1
Kurinna, S.2
Suck, G.3
-
4
-
-
84887623828
-
Crosstalk between apoptosis, necrosis and autophagy
-
1:CAS:528:DC%2BC3sXhtVCgsLfK
-
Nikoletopoulou V, Markaki M, Palikaras K, Tavernarakis N (2013) Crosstalk between apoptosis, necrosis and autophagy. Biochimica Et Biophysica Acta-Molecular Cell Research 1833:3448-3459
-
(2013)
Biochimica et Biophysica Acta-Molecular Cell Research
, vol.1833
, pp. 3448-3459
-
-
Nikoletopoulou, V.1
Markaki, M.2
Palikaras, K.3
Tavernarakis, N.4
-
5
-
-
62449215042
-
The Bcl-2 family in autoimmune and degenerative disorders
-
1:CAS:528:DC%2BD1MXivFSnsb4%3D 19172396
-
Merino D, Bouillet P (2009) The Bcl-2 family in autoimmune and degenerative disorders. Apoptosis 14:570-583
-
(2009)
Apoptosis
, vol.14
, pp. 570-583
-
-
Merino, D.1
Bouillet, P.2
-
6
-
-
18044363070
-
Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation
-
1:CAS:528:DC%2BD2MXjtl2ktrc%3D 15843899
-
Koc M, Nad'ova Z, Truksa J, Ehrlichova M, Kovar J (2005) Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation. Apoptosis 10:381-393
-
(2005)
Apoptosis
, vol.10
, pp. 381-393
-
-
Koc, M.1
Nad'Ova, Z.2
Truksa, J.3
Ehrlichova, M.4
Kovar, J.5
-
7
-
-
0033574578
-
The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides
-
1:CAS:528:DyaK1MXis1Gmtrg%3D 10196212
-
Ackermann EJ, Taylor JK, Narayana R, Bennett CF (1999) The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides. J Biol Chem 274:11245-11252
-
(1999)
J Biol Chem
, vol.274
, pp. 11245-11252
-
-
Ackermann, E.J.1
Taylor, J.K.2
Narayana, R.3
Bennett, C.F.4
-
8
-
-
0032566717
-
A functional role for mitochondrial protein kinase C alpha in Bcl2 phosphorylation and suppression of apoptosis
-
1:CAS:528:DyaK1cXmsVGlsr8%3D 9738012
-
Ruvolo PP, Deng XM, Carr BH, May WS (1998) A functional role for mitochondrial protein kinase C alpha in Bcl2 phosphorylation and suppression of apoptosis. J Biol Chem 273:25436-25442
-
(1998)
J Biol Chem
, vol.273
, pp. 25436-25442
-
-
Ruvolo, P.P.1
Deng, X.M.2
Carr, B.H.3
May, W.S.4
-
9
-
-
0031036307
-
Raf-1/bcl-2 phosphorylation: A step from microtubule damage to cell death
-
1:CAS:528:DyaK2sXktVagsg%3D%3D 8988053
-
Blagosklonny MV, Giannakakou P, el-Deiry WS et al (1997) Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. Cancer Res 57:130-135
-
(1997)
Cancer Res
, vol.57
, pp. 130-135
-
-
Blagosklonny, M.V.1
Giannakakou, P.2
El-Deiry, W.S.3
-
10
-
-
0033230015
-
BCL-2 and glutathione: Alterations in cellular redox state that regulate apoptosis sensitivity
-
1:CAS:528:DyaK1MXns1ymsrs%3D 10569627
-
Voehringer DW (1999) BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity. Free Radic Biol Med 27:945-950
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 945-950
-
-
Voehringer, D.W.1
-
11
-
-
70349172938
-
Apoptosis and glutathione: Beyond an antioxidant
-
1:CAS:528:DC%2BD1MXhtFajt7vO 19662025
-
Franco R, Cidlowski JA (2009) Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 16:1303-1314
-
(2009)
Cell Death Differ
, vol.16
, pp. 1303-1314
-
-
Franco, R.1
Cidlowski, J.A.2
-
12
-
-
50849141073
-
Glutathione and apoptosis
-
1:CAS:528:DC%2BD1cXhtVSkurnN
-
Circu ML, Aw TY (2008) Glutathione and apoptosis. Free Radical Res 42:689-706
-
(2008)
Free Radical Res
, vol.42
, pp. 689-706
-
-
Circu, M.L.1
Aw, T.Y.2
-
13
-
-
84855469557
-
Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione
-
1:CAS:528:DC%2BC38XlsVyhsA%3D%3D 3253244 22115789
-
Wilkins HM, Marquardt K, Lash LH, Linseman DA (2012) Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione. Free Radic Biol Med 52:410-419
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 410-419
-
-
Wilkins, H.M.1
Marquardt, K.2
Lash, L.H.3
Linseman, D.A.4
-
14
-
-
34848858255
-
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound with a ferin A with concomitant protection by N-acetyl cysteine
-
1:CAS:528:DC%2BD2sXhtFSrtrrJ 17874299
-
Malik F, Kumar A, Bhushan S et al (2007) Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound with a ferin A with concomitant protection by N-acetyl cysteine. Apoptosis 12:2115-2133
-
(2007)
Apoptosis
, vol.12
, pp. 2115-2133
-
-
Malik, F.1
Kumar, A.2
Bhushan, S.3
-
15
-
-
34250804439
-
Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death
-
1:CAS:528:DC%2BD2sXmvVyqu78%3D 17415663
-
Papa L, Gomes E, Rockwell P (2007) Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death. Apoptosis 12:1389-1405
-
(2007)
Apoptosis
, vol.12
, pp. 1389-1405
-
-
Papa, L.1
Gomes, E.2
Rockwell, P.3
-
16
-
-
84887988855
-
Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells
-
1:CAS:528:DC%2BC3sXhslertbrK 24383086
-
Shen S, Zhang Y, Zhang R, Gong X (2013) Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. Biochem Biophys Res Commun 441:519-524
-
(2013)
Biochem Biophys Res Commun
, vol.441
, pp. 519-524
-
-
Shen, S.1
Zhang, Y.2
Zhang, R.3
Gong, X.4
-
17
-
-
0036213362
-
Hypericin - A new antiviral and antitumor photosensitizer: Mechanism of action and interaction with biological macromolecules
-
1:CAS:528:DC%2BD38XitFSmsbc%3D 11899265
-
Miskovsky P (2002) Hypericin - A new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules. Curr Drug Targets 3:55-84
-
(2002)
Curr Drug Targets
, vol.3
, pp. 55-84
-
-
Miskovsky, P.1
-
18
-
-
33947144570
-
Induction of heme-oxygenase 1 requires the p38(MAPK) and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy
-
1:CAS:528:DC%2BD2sXivVSht7Y%3D 17219054
-
Kocanova S, Buytaert E, Matroule JY et al (2007) Induction of heme-oxygenase 1 requires the p38(MAPK) and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy. Apoptosis 12:731-741
-
(2007)
Apoptosis
, vol.12
, pp. 731-741
-
-
Kocanova, S.1
Buytaert, E.2
Matroule, J.Y.3
-
19
-
-
77349111247
-
Interaction dynamics of hypericin with low-density lipoproteins and U87-MG cells
-
1:CAS:528:DC%2BC3cXivVOluro%3D 20083174
-
Huntosova V, Alvarez L, Bryndzova L et al (2010) Interaction dynamics of hypericin with low-density lipoproteins and U87-MG cells. Int J Pharm 389:32-40
-
(2010)
Int J Pharm
, vol.389
, pp. 32-40
-
-
Huntosova, V.1
Alvarez, L.2
Bryndzova, L.3
-
20
-
-
33745827379
-
Characterization of the interaction of hypericin with protein kinase c in U-87 MG human glioma cells
-
1:CAS:528:DC%2BD28Xmt1eju7g%3D 16396605
-
Kocanova S, Hornakova T, Hritz J et al (2006) Characterization of the interaction of hypericin with protein kinase c in U-87 MG human glioma cells. Photochem Photobiol 82:720-728
-
(2006)
Photochem Photobiol
, vol.82
, pp. 720-728
-
-
Kocanova, S.1
Hornakova, T.2
Hritz, J.3
-
21
-
-
84901592759
-
The role of anti-apoptotic protein kinase Calpha in response to hypericin photodynamic therapy in U-87 MG cells
-
1:CAS:528:DC%2BC2cXmtFWit70%3D
-
Dzurova L, Petrovajova D, Nadova Z, Huntosova V, Miskovsky P, Stroffekova K (2014) The role of anti-apoptotic protein kinase Calpha in response to hypericin photodynamic therapy in U-87 MG cells. Photodiagn Photodyn Ther 11:213-226
-
(2014)
Photodiagn Photodyn Ther
, vol.11
, pp. 213-226
-
-
Dzurova, L.1
Petrovajova, D.2
Nadova, Z.3
Huntosova, V.4
Miskovsky, P.5
Stroffekova, K.6
-
22
-
-
84879096725
-
Monitoring of singlet oxygen luminescence and mitochondrial autofluorescence after illumination of hypericin/mitochondria complex: A time-resolved study
-
Petrovajova D, Jancura D, Miskovsky P et al (2013) Monitoring of singlet oxygen luminescence and mitochondrial autofluorescence after illumination of hypericin/mitochondria complex: a time-resolved study. Laser Phys Lett 10:7
-
(2013)
Laser Phys Lett
, vol.10
, pp. 7
-
-
Petrovajova, D.1
Jancura, D.2
Miskovsky, P.3
-
23
-
-
77955009426
-
Synchrotron based Fourier-transform infrared microspectroscopy as sensitive technique for the detection of early apoptosis in U-87 MG cells
-
1:CAS:528:DC%2BC3cXhtFajt7rF
-
Buriankova L, Nadova Z, Jancura D et al (2010) Synchrotron based Fourier-transform infrared microspectroscopy as sensitive technique for the detection of early apoptosis in U-87 MG cells. Laser Phys Lett 7:613-620
-
(2010)
Laser Phys Lett
, vol.7
, pp. 613-620
-
-
Buriankova, L.1
Nadova, Z.2
Jancura, D.3
-
24
-
-
37249024685
-
High level of low-density lipoprotein receptors enhance hypericin uptake by U-87 MG cells in the presence of LDL
-
1:CAS:528:DC%2BD1cXht1yltb8%3D 18173711
-
Kascakova S, Nadova Z, Mateasik A et al (2008) High level of low-density lipoprotein receptors enhance hypericin uptake by U-87 MG cells in the presence of LDL. Photochem Photobiol 84:120-127
-
(2008)
Photochem Photobiol
, vol.84
, pp. 120-127
-
-
Kascakova, S.1
Nadova, Z.2
Mateasik, A.3
-
25
-
-
27944468179
-
Cell death induced by taxanes in breast cancer cells: Cytochrome c is released in resistant but not in sensitive cells
-
1:CAS:528:DC%2BD2MXht12it7nM 16309219
-
Ehrlichova M, Koc M, Truksa J, Naldova Z, Vaclavikova R, Kovarr J (2005) Cell death induced by taxanes in breast cancer cells: cytochrome c is released in resistant but not in sensitive cells. Anticancer Res 25:4215-4224
-
(2005)
Anticancer Res
, vol.25
, pp. 4215-4224
-
-
Ehrlichova, M.1
Koc, M.2
Truksa, J.3
Naldova, Z.4
Vaclavikova, R.5
Kovarr, J.6
-
27
-
-
84865221535
-
Cell death response of U87 glioma cells on hypericin photoactivation is mediated by dynamics of hypericin subcellular distribution and its aggregation in cellular organelles
-
1:CAS:528:DC%2BC38Xht1WrsLrK 22729350
-
Huntosova V, Nadova Z, Dzurova L, Jakusova V, Sureau F, Miskovsky P (2012) Cell death response of U87 glioma cells on hypericin photoactivation is mediated by dynamics of hypericin subcellular distribution and its aggregation in cellular organelles. Photochem Photobiol Sci 11:1428-1436
-
(2012)
Photochem Photobiol Sci
, vol.11
, pp. 1428-1436
-
-
Huntosova, V.1
Nadova, Z.2
Dzurova, L.3
Jakusova, V.4
Sureau, F.5
Miskovsky, P.6
-
28
-
-
77954758155
-
PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta Are Essential Mediators of the Response of Normal Human Epidermal Keratinocytes to Differentiating Agents
-
1:CAS:528:DC%2BC3cXovVCmtrw%3D 3120227 20445555
-
Adhikary G, Chew YC, Reece EA, Eckert RL (2010) PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta Are Essential Mediators of the Response of Normal Human Epidermal Keratinocytes to Differentiating Agents. J Invest Dermatol 130:2017-2030
-
(2010)
J Invest Dermatol
, vol.130
, pp. 2017-2030
-
-
Adhikary, G.1
Chew, Y.C.2
Reece, E.A.3
Eckert, R.L.4
-
29
-
-
5644271449
-
Protein kinase C alpha expression in breast and ovarian cancer
-
1:CAS:528:DC%2BD2cXotVGgs7k%3D 15459489
-
Lahn M, Kohler G, Sundell K et al (2004) Protein kinase C alpha expression in breast and ovarian cancer. Oncology 67:1-10
-
(2004)
Oncology
, vol.67
, pp. 1-10
-
-
Lahn, M.1
Kohler, G.2
Sundell, K.3
-
30
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
1:CAS:528:DC%2BC3MXptFKnt7k%3D 3135394 21746850
-
Finkel T (2011) Signal transduction by reactive oxygen species. J Cell Biol 194:7-15
-
(2011)
J Cell Biol
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
31
-
-
79952700828
-
Bcl-2 proteins and mitochondria-Specificity in membrane targeting for death
-
1:CAS:528:DC%2BC3MXjsFCgs7Y%3D 21056595
-
Lindsay J, Esposti MD, Gilmore AP (2011) Bcl-2 proteins and mitochondria-Specificity in membrane targeting for death. Biochim Biophys Acta 1813:532-539
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 532-539
-
-
Lindsay, J.1
Esposti, M.D.2
Gilmore, A.P.3
-
32
-
-
0035073292
-
Phosphorylation of Bcl2 and regulation of apoptosis
-
1:CAS:528:DC%2BD3MXjt1egs78%3D 11368354
-
Ruvolo PP, Deng X, May WS (2001) Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia 15:515-522
-
(2001)
Leukemia
, vol.15
, pp. 515-522
-
-
Ruvolo, P.P.1
Deng, X.2
May, W.S.3
-
33
-
-
0032967444
-
Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: Studies in vivo and in vitro
-
1:CAS:528:DyaK1MXjsVOlu78%3D 10336888
-
Esteve JM, Mompo J, De La Asuncion JG et al (1999) Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro. Faseb J 13:1055-1064
-
(1999)
Faseb J
, vol.13
, pp. 1055-1064
-
-
Esteve, J.M.1
Mompo, J.2
De La Asuncion, J.G.3
-
34
-
-
35748976238
-
Glutathione binding to the Bcl-2 homology-3 domain groove - A molecular basis for Bcl-2 antioxidant function at mitochondria
-
1:CAS:528:DC%2BD2sXhtV2ntbjK 2386251 17690097
-
Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA (2007) Glutathione binding to the Bcl-2 homology-3 domain groove - A molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem 282:29296-29304
-
(2007)
J Biol Chem
, vol.282
, pp. 29296-29304
-
-
Zimmermann, A.K.1
Loucks, F.A.2
Schroeder, E.K.3
Bouchard, R.J.4
Tyler, K.L.5
Linseman, D.A.6
-
35
-
-
20444363788
-
Apoptosis vs. Necrosis: Glutathione-mediated cell death during rewarming of rat hepatocytes
-
1:CAS:528:DC%2BD2MXltFCqs74%3D 15949704
-
Vairetti M, Ferrigno A, Bertone R, Richelmi P, Berte F, Freitas I (2005) Apoptosis vs. necrosis: glutathione-mediated cell death during rewarming of rat hepatocytes. Biochim Biophys Acta 1740:367-374
-
(2005)
Biochim Biophys Acta
, vol.1740
, pp. 367-374
-
-
Vairetti, M.1
Ferrigno, A.2
Bertone, R.3
Richelmi, P.4
Berte, F.5
Freitas, I.6
-
36
-
-
7244246885
-
Decreased cardiac mitochondrial NADP(+)-isocitrate dehydrogenase activity and expression: A marker of oxidative stress in hypertrophy development
-
1:CAS:528:DC%2BD2cXhtVaqtrrE 15271667
-
Benderdour M, Charron G, Comte B et al (2004) Decreased cardiac mitochondrial NADP(+)-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development. Am J Physiol Heart Circ Physiol 287:H2122-H2131
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, pp. H2122-H2131
-
-
Benderdour, M.1
Charron, G.2
Comte, B.3
-
37
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
1:CAS:528:DyaK3sXms1Omtr8%3D 7503812
-
Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
38
-
-
0027717968
-
Bcl-2 inhibition of neural death - Decreased generation of reactive oxygen species
-
1:CAS:528:DyaK2cXisVOk 8235659
-
Kane DJ, Sarafian TA, Anton R et al (1993) Bcl-2 inhibition of neural death - decreased generation of reactive oxygen species. Science 262:1274-1277
-
(1993)
Science
, vol.262
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
-
39
-
-
0033735274
-
Redox Aspects of Bcl-2 Function
-
1:CAS:528:DC%2BD3cXnslKlsbc%3D 11229367
-
Voehringer DW, Meyn RE (2000) Redox Aspects of Bcl-2 Function. Antioxid Redox Signal 2:537-550
-
(2000)
Antioxid Redox Signal
, vol.2
, pp. 537-550
-
-
Voehringer, D.W.1
Meyn, R.E.2
-
40
-
-
0031724265
-
Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-deficient mice
-
1:CAS:528:DyaK1cXkslKitrs%3D 9681465
-
Hochman A, Sternin H, Gorodin S et al (1998) Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-deficient mice. J Neurochem 71:741-748
-
(1998)
J Neurochem
, vol.71
, pp. 741-748
-
-
Hochman, A.1
Sternin, H.2
Gorodin, S.3
|