Dietary fat and fiber intakes are not associated with patterns of urinary estrogen metabolites in premenopausal women

Journal of Nutrition

Volumn 145, Issue 9, 2015, Pages 2109-2116

  Oh, Hannah ^a,b   Smith Warner, Stephanie A ^a   Tamimi, Rulla M ^a,b   Wang, Molin ^a,b   Xu, Xia ^c   Hankinson, Susan E ^a,b,d   Fuhrman, Barbara J ^e,f   Ziegler, Regina G ^e   Eliassen, A Heather ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Diet; Estrogen; Estrogen metabolites; Fat; Fiber; Premenopausal

Indexed keywords

17 EPIESTRIOL; 4 METHOXYESTRADIOL; ESTROGEN; FAT; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; 4-METHOXYESTRADIOL; ESTRADIOL; FAT INTAKE; PROGESTERONE;

ADULT; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIETARY FIBER; ESTROGEN EXCRETION; ESTROGEN METABOLISM; ESTROGEN SYNTHESIS; ESTROGEN URINE LEVEL; FAT INTAKE; FEMALE; FOOD FREQUENCY QUESTIONNAIRE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; PREMENOPAUSE; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; ADMINISTRATION AND DOSAGE; ANALOGS AND DERIVATIVES; BIOAVAILABILITY; BLOOD; BODY MASS; BREAST TUMOR; CASE CONTROL STUDY; FOLLOW UP; METABOLISM; RISK FACTOR; STATISTICAL MODEL; URINE;

ADULT; BIOLOGICAL AVAILABILITY; BODY MASS INDEX; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DIETARY FATS; DIETARY FIBER; ESTRADIOL; ESTROGENS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LINEAR MODELS; PREMENOPAUSE; PROGESTERONE; REPRODUCIBILITY OF RESULTS; RISK FACTORS; TANDEM MASS SPECTROMETRY;

EID: 84941065498     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.115.212779     Document Type: Article

References (46)

1. Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006;354:270-82.
2. Flototto T, Djahansouzi S, Glaser M, Hanstein B, Niederacher D, Brumm C, Beckmann MW. Hormones and hormone antagonists: mechanisms of action in carcinogenesis of endometrial and breast cancer. Horm Metab Res 2001;33(8):451-7.
3. Yager JD. Endogenous estrogens as carcinogens through metabolic activation. J Natl Cancer Inst Monogr 2000;27:67-73.
4. Seeger H, Wallwiener D, Kraemer E, Mueck AO. Comparison of possible carcinogenic estradiol metabolites: effects on proliferation, apoptosis and metastasis of human breast cancer cells. Maturitas 2006;54:72-7.
5. Cavalieri E, Frenkel K, Liehr JG, Rogan E, Roy D. Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 2000;27:75-93.
6. Kono S, Merriam GR, Brandon DD, Loriaux DL, Lipsett MB, Fujino T. Radioimmunoassay and metabolic clearance rate of catecholestrogens, 2-hydroxyestrone and 2-hydroxyestradiol in man. J Steroid Biochem 1983;19: 1B:627-33.
7. Pfeiffer E, Graf E, Gerstner S, Metzler M. Stimulation of estradiol glucuronidation: a protective mechanism against estradiol-mediated carcinogenesis? Mol Nutr Food Res 2006;50:385-9.
8. Yager JD, Liehr JG. Molecular mechanisms of estrogen carcinogenesis. Annu Rev Pharmacol Toxicol 1996;36:203-32.
9. Zhu BT, Conney AH. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 1998;19:1-27.
10. Dallal CM, Tice JA, Buist DS, Bauer DC, Lacey JV, Jr., Cauley JA, Hue TF, Lacroix A, Falk RT, Pfeiffer RM, et al. Estrogen metabolism and breast cancer risk among postmenopausal women: a case-cohort study within B~FIT. Carcinogenesis 2014;35:346-55.
11. Falk RT, Brinton LA, Dorgan JF, Fuhrman BJ, Veenstra TD, Xu X, Gierach GL. Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study. Breast cancer research. Breast Cancer Res 2013;15:R34.
12. Fuhrman BJ, Schairer C, Gail MH, Boyd-Morin J, Xu X, Sue LY, Buys SS, Isaacs C, Keefer LK, Veenstra TD, et al. Estrogen metabolism and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 2012;104:326-39.
13. Eliassen AH, Spiegelman D, Xu X, Keefer LK, Veenstra TD, Barbieri RL, Willett WC, Hankinson SE, Ziegler RG. Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women. Cancer Res 2012;72:696-706.
14. Xie J, Eliassen AH, Xu X, Matthews CE, Hankinson SE, Ziegler RG, Tworoger SS. Body size in relation to urinary estrogens and estrogen metabolites (EM) among premenopausal women during the luteal phase. Horm Cancer 2012;3:249-60.
15. Fortner RT, Hankinson SE, Schairer C, Xu X, Ziegler RG, Eliassen AH. Association between reproductive factors and urinary estrogens and estrogen metabolites in premenopausal women. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012;21(6):959-68.
16. Matthews CE, Fortner RT, Xu X, Hankinson SE, Eliassen AH, Ziegler RG. Association between physical activity and urinary estrogens and estrogen metabolites in premenopausal women. J Clin Endocrinol Metab 2012;97:3724-33.
17. Gu F, Caporaso NE, Schairer C, Fortner RT, Xu X, Hankinson SE, Eliassen AH, Ziegler RG. Urinary concentrations of estrogens and estrogen metabolites and smoking in caucasian women. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013;22(1):58-68.
18. Fortner RT, Oh H, Daugherty SE, Xu X, Hankinson SE, Ziegler RG, Eliassen AH. Analgesic Use and Patterns of Estrogen Metabolism in Premenopausal Women. Horm Cancer 2014;5:104-12.
19. Arts CJ, Govers CA, van den Berg H, WoltersMG, van Leeuwen P, Thijssen JH. In vitro binding of estrogens by dietary fiber and the in vivo apparent digestibility tested in pigs. J Steroid Biochem Mol Biol 1991;38:621-8.
20. Cortes VA, Busso D, Maiz A, Arteaga A, Nervi F, Rigotti A. Physiological and pathological implications of cholesterol. Front Biosci (Landmark Ed) 2014;19:416-28.
21. Cui X, Rosner B, Willett WC, Hankinson SE. Dietary fat, fiber, and carbohydrate intake and endogenous hormone levels in premenopausal women. Horm Cancer 2010;1:265-76.
22. Goldin BR, Adlercreutz H, Gorbach SL, Warram JH, Dwyer JT, Swenson L, Woods MN. Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. N Engl JMed 1982;307:1542-7.
23. Prentice R, Thompson D, Clifford C, Gorbach S, Goldin B, Byar D. Dietary fat reduction and plasma estradiol concentration in healthy postmenopausal women. The Women's Health Trial Study Group. J Natl Cancer Inst 1990;82:129-34.
24. Goldin BR, Adlercreutz H, Gorbach SL, Woods MN, Dwyer JT, Conlon T, Bohn E, Gershoff SN. The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women. Am J Clin Nutr 1986;44:945-53.
25. Young LR, Raatz SK, Thomas W, Redmon JB, Kurzer MS. Total dietary fat and omega-3 fatty acids have modest effects on urinary sex hormones in postmenopausal women. Nutr Metab 2013;10:36.
26. Aubertin-Leheudre M, Gorbach S, Woods M, Dwyer JT, Goldin B, Adlercreutz H. Fat/fiber intakes and sex hormones in healthy premenopausal women in USA. J Steroid Biochem Mol Biol 2008;112:32-9.
27. Xu X, Veenstra TD, Fox SD, Roman JM, Issaq HJ, Falk R, Saavedra JE, Keefer LK, Ziegler RG. Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatographymass spectrometry. Anal Chem 2005;77:6646-54.
28. Fortner RT, Eliassen AH, Spiegelman D, Willett WC, Barbieri RL, Hankinson SE. Premenopausal endogenous steroid hormones and breast cancer risk: results from the Nurses' Health Study II. Breast cancer research. Breast Cancer Res 2013;15:R19.
29. Eliassen AH, Ziegler RG, Rosner B, Veenstra TD, Roman JM, Xu X, Hankinson SE. Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2-to 3-year period in premenopausal women. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):2860-8.
30. Haytowitz DB. Information from USDA's Nutrient Data Bank. J Nutr 1995;125:1952-5.
31. Salvini S, Hunter DJ, Sampson L, Stampfer MJ, Colditz GA, Rosner B, Willett WC. Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 1989;18:858-67.
32. Willett WC. Nutritional epidemiology. 2nd ed. New York: Oxford University Press, 1998.
33. Falk RT, Xu X, Keefer L, Veenstra TD, Ziegler RG. A liquid chromatography-mass spectrometry method for the simultaneous measurement of 15 urinary estrogens and estrogen metabolites: assay reproducibility and interindividual variability. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3411-8.
34. Ziegler RG, Faupel-Badger JM, Sue LY, Fuhrman BJ, Falk RT, Boyd-Morin J, Henderson MK, Hoover RN, Veenstra TD, Keefer LK, et al. A new approach to measuring estrogen exposure and metabolism in epidemiologic studies. J Steroid Biochem Mol Biol 2010;121:538-45.
35. Rosner B. Percentage points for a generalized ESD many-outlier procedure. Technometrics 1983;25:165-72.
36. Li F, Hullar MA, Schwarz Y, Lampe JW. Human gut bacterial communities are altered by addition of cruciferous vegetables to a controlled fruit-and vegetable-free diet. J Nutr 2009;139:1685-91.
37. Maukonen J, Saarela M. Human gut microbiota: does diet matter? The Proceedings of the Nutrition Society 2014:1-14.
38. RussellWR, Gratz SW, Duncan SH, Holtrop G, Ince J, Scobbie L, Duncan G, Johnstone AM, Lobley GE, Wallace RJ, et al. High-protein, reducedcarbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. Am J Clin Nutr 2011;93:1062-72.
39. Fuhrman BJ, Spencer Feigelson H, Flores R, Gail MH, Xu X, Ravel J, Goedert JJ. Associations of the fecal microbiome with urinary estrogens and estrogen metabolites in postmenopausal women. J Clin Endocrinol Metab 2014;99:4632-40.
40. Adlercreutz H, Martin F. Biliary excretion and intestinal metabolism of progesterone and estrogens in man. J Steroid Biochem 1980;13:231-44.
41. Flores R, Shi J, Fuhrman B, Xu X, Veenstra TD, Gail MH, Gajer P, Ravel J, Goedert JJ. Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study. J Transl Med 2012;10:253.
42. Adlercreutz H, Pulkkinen MO, Hamalainen EK, Korpela JT. Studies on the role of intestinal bacteria in metabolism of synthetic and natural steroid hormones. J Steroid Biochem 1984;20:217-29.
43. Wong GY, Bradlow L, Sepkovic D, Mehl S, Mailman J, Osborne MP. Dose-ranging study of indole-3-carbinol for breast cancer prevention. J Cell Biochem Suppl 1997;28-29:111-6.
44. Mori M, Tominaga T, Tamaoki BI. Steroid metabolism in normal mammary gland and in the dimethylbenzanthracene-induced mammary tumor of rats. Endocrinology 1978;102:1387-97.
45. King DE, Mainous, 3rd AG, Lambourne CA. Trends in dietary fiber intake in the United States, 1999-2008. J Acad Nutr Diet 2012;112:642-8.
46. Wakai K, Naito M, Date C, Iso H, Tamakoshi A, Group JS. Dietary intakes of fat and total mortality among Japanese populations with a low fat intake: the Japan Collaborative Cohort (JACC) Study. Nutr Metab (Lond) 2014;11:12.