Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice

Journal of Lipid Research

Volumn 56, Issue 9, 2015, Pages 1691-1700

  De Bari, Ornella ^a   Wang, Tony Y ^a,b   Liu, Min ^c   Portincasa, Piero ^d   Wang, David Q H ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

Bile flow; Bile salt; Biliary secretion; Estrogen receptor subtype ; G protein coupled receptor 30; Lith gene; Micelle; Vesicle

Indexed keywords

BILE ACID; CHOLESTEROL DERIVATIVE; CHOLESTEROL MONOHYDRATE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; G PROTEIN COUPLED RECEPTOR 30; MUCIN; UNCLASSIFIED DRUG; CHOLESTEROL; ESTRADIOL; G PROTEIN COUPLED RECEPTOR; GPR30 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL CRYSTALLIZATION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; CRYSTALLIZATION; ENZYME ACTIVATION; FEMALE; GALLBLADDER EMPTYING; GALLSTONE FORMATION; HETEROZYGOSITY; HOMOZYGOSITY; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; LIPID COMPOSITION; LIPID METABOLISM; LIPID TRANSPORT; MALE; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE TRAIT LOCUS MAPPING; RISK FACTOR; ANIMAL; GALLSTONE; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL; CRYSTALLIZATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GALLSTONES; HUMANS; MICE; MICE, KNOCKOUT; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84940970234     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M059121     Document Type: Article

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