Association between drug-specific indicators of prescribing quality and quality of drug treatment: A validation study

Pharmacoepidemiology and Drug Safety

Volumn 24, Issue 9, 2015, Pages 906-914

  Wallerstedt, Susanna M ^a   Belfrage, Björn ^b   Fastbom, Johan ^c  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b Närhälsan Dals Ed Health Center Dals Ed   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Drug therapy; Health care quality assessment; Indicator; Pharmacoepidemiology; Validity

Indexed keywords

ANALGESIC AGENT; ANTIARRHYTHMIC AGENT; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTITHROMBOCYTIC AGENT; BENZODIAZEPINE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; ERGOTAMINE; GASTROINTESTINAL AGENT; HYPNOTIC AGENT; NEUROLEPTIC AGENT; PSYCHOTROPIC AGENT; VASODILATOR AGENT;

AGE; AGED; ARTICLE; ASSESSMENT OF HUMANS; COGNITION; CONCURRENT VALIDITY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; GOLD STANDARD; HIP FRACTURE; HUMAN; INAPPROPRIATE PRESCRIBING; MAJOR CLINICAL STUDY; MALE; MUSCLE; PRESCRIPTION; PRIORITY JOURNAL; SCREENING TOOL OF OLDER PERSONS POTENTIALLY INAPPROPRIATE PRESCRIPTION; SCREENING TOOL TO ALERT TO RIGHT TREATMENT; SENSITIVITY AND SPECIFICITY; SEX; VALIDATION STUDY; CONTROLLED STUDY; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FRANCE; GERMANY; HIP FRACTURES; PREVENTION AND CONTROL; RANDOMIZED CONTROLLED TRIAL; STANDARDS; SWEDEN; TRENDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; DRUG PRESCRIPTIONS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; FRANCE; GERMANY; HIP FRACTURES; HUMANS; INAPPROPRIATE PRESCRIBING; MALE; SWEDEN;

EID: 84940960275     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.3827     Document Type: Article

References (33)

1. Gillaizeau F, Chan E, Trinquart L, et al. Computerized advice on drug dosage to improve prescribing practice. Cochrane Database Syst Rev. 2013; 11 CD002894.
2. Patterson SM, Hughes C, Kerse N, Cardwell CR, Bradley MC. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev. 2012; 5 CD008165.
3. Alldred DP, Raynor DK, Hughes C, Barber N, Chen TF, Spoor P. Interventions to optimise prescribing for older people in care homes. Cochrane Database Syst Rev. 2013; 2 CD009095.
4. Hoven JL, Haaijer-Ruskamp FM, Vander Stichele RH. Indicators of prescribing quality in drug utilisation research: report of a European meeting (DURQUIM, 13-15 May 2004). Eur J Clin Pharmacol. 2005; 60: 831-4.
5. Santos AP, Silva DT, Alves-Conceicao V, Antoniolli AR, Lyra DP, Jr. Conceptualizing and measuring potentially inappropriate drug therapy. J Clin Pharm Ther. 2015; 40: 167-76.
6. Fastbom J, Johnell K. National indicators for quality of drug therapy in older persons: the Swedish experience from the first 10years. Drugs Aging. 2015; 32: 189-99.
7. Kaufmann CP, Tremp R, Hersberger KE, Lampert ML. Inappropriate prescribing: a systematic overview of published assessment tools. Eur J Clin Pharmacol. 2014; 70: 1-11.
8. Bladh L, Ottosson E, Karlsson J, Klintberg L, Wallerstedt SM. Effects of a clinical pharmacist service on health-related quality of life and prescribing of drugs: a randomised controlled trial. BMJ Qual Saf. 2011; 20: 738-46.
9. Sjöberg C, Edward C, Fastbom J, et al. Association between multi-dose drug dispensing and quality of drug treatment-a register-based study. PLoS One. 2011; 6 e26574.
10. Wallerstedt SM, Fastbom J, Johnell K, Sjöberg C, Landahl S, Sundström A. Drug treatment in older people before and after the transition to a multi-dose drug dispensing system-a longitudinal analysis. PLoS One. 2013; 8 e67088.
11. Johnell K, Fastbom J, Rosen M, Leimanis A. Inappropriate drug use in the elderly: a nationwide register-based study. Ann Pharmacother. 2007; 41: 1243-8.
12. Bongue B, Laroche ML, Gutton S, et al. Potentially inappropriate drug prescription in the elderly in France: a population-based study from the French National Insurance Healthcare system. Eur J Clin Pharmacol. 2011; 67: 1291-9.
13. Schubert I, Kupper-Nybelen J, Ihle P, Thurmann P. Prescribing potentially inappropriate medication (PIM) in Germany's elderly as indicated by the PRISCUS list. An analysis based on regional claims data. Pharmacoepidemiol Drug Saf 2013; 22: 719-27.
14. Laroche ML, Charmes JP, Merle L. Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol. 2007; 63: 725-31.
15. Holt S, Schmiedl S, Thurmann PA. Potentially inappropriate medications in the elderly: the PRISCUS list. Dtsch Arztebl Int. 2010; 107: 543-51.
16. American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012; 60: 616-31.
17. Morin L, Fastbom J, Laroche ML, Johnell K. Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates. Br J Clin Pharmacol. 2015; Epub ahead of print.
18. Andersen M. Is it possible to measure prescribing quality using only prescription data? Basic Clin Pharmacol Toxicol. 2006; 98: 314-9.
19. Gallagher PF, O'Connor MN, O'Mahony D. Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria. Clin Pharmacol Ther. 2011; 89: 845-54.
20. Gallagher P, Ryan C, Byrne S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther. 2008; 46: 72-83.
21. Sjöberg C, Wallerstedt SM. Effects of medication reviews performed by a physician on treatment with fracture-preventing and fall-risk-increasing drugs in older adults with hip fracture-a randomized controlled study. J Am Geriatr Soc. 2013; 61: 1464-72.
22. National Board of Health and Welfare. Indikatorer för god läkemedelsterapi hos äldre [Indicators for drug treatment in older people]. 2010.
23. Belfrage B, Koldestam A, Sjöberg C, Wallerstedt SM. Prevalence of suboptimal drug treatment in patients with and without multidose drug dispensing-a cross-sectional study. Eur J Clin Pharmacol. 2014; 70: 867-72.
24. Brilleman SL, Salisbury C. Comparing measures of multimorbidity to predict outcomes in primary care: a cross sectional study. Fam Pract. 2013; 30: 172-8.
25. Steinman MA, Landefeld CS, Rosenthal GE, Berthenthal D, Sen S, Kaboli PJ. Polypharmacy and prescribing quality in older people. J Am Geriatr Soc. 2006; 54: 1516-23.
26. Hill-Taylor B, Sketris I, Hayden J, Byrne S, O'Sullivan D, Christie R. Application of the STOPP/START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical, humanistic and economic impact. J Clin Pharm Ther. 2013; 38: 360-72.
27. Kanis JA, Johnell O, De Laet C, Jonsson B, Oden A, Ogelsby AK. International variations in hip fracture probabilities: implications for risk assessment. J Bone Miner Res. 2002; 17: 1237-44.
28. Sjöberg C, Bladh L, Klintberg L, Mellström D, Ohlsson C, Wallerstedt SM. Treatment with fall-risk-increasing and fracture-preventing drugs before and after a hip fracture: an observational study. Drugs Aging. 2010; 27: 653-61.
29. Belfrage B, Koldestam A, Sjöberg C, Wallerstedt SM. Number of drugs in the medication list as an indicator of prescribing quality: a validation study of polypharmacy indicators in older hip fracture patients. Eur J Clin Pharmacol. 2015; 71: 363-8.
30. Christensen M, Lundh A. Medication review in hospitalised patients to reduce morbidity and mortality. Cochrane Database Syst Rev. 2013; 2 CD008986.
31. Wallerstedt SM, Kindblom JM, Nylén K, Samuelsson O, Strandell A. Medication reviews for nursing home residents to reduce mortality and hospitalization: systematic review and meta-analysis. Br J Clin Pharmacol. 2014; 78: 488-97.
32. Hohl CM, Wickham ME, Sobolev B, et al. The effect of early in-hospital medication review on health outcomes: a systematic review. Br J Clin Pharmacol. 2015; 80: 51-61.
33. Kwint HF, Bermingham L, Faber A, Gussekloo J, Bouvy ML. The relationship between the extent of collaboration of general practitioners and pharmacists and the implementation of recommendations arising from medication review: a systematic review. Drugs Aging. 2013; 30: 91-102.