Glucocorticoid dexamethasone down-regulates basal and vitamin D3 induced cathelicidin expression in human monocytes and bronchial epithelial cell line

Immunobiology

Volumn 221, Issue 2, 2016, Pages 245-252

  Kulkarni, Nikhil Nitin ^a   Gunnarsson, Hörður Ingi ^a   Yi, Zhiqian ^a   Gudmundsdottir, Steinunn ^a   Sigurjonsson, Olafur E ^a,b,c   Agerberth, Birgitta ^d   Gudmundsson, Gudmundur H ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^c REYKJAVIK UNIVERSITY   (Iceland)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anti inflammatory; Antimicrobial polypeptides; CAMP gene; Glucocorticoid Receptor; LL 37

Indexed keywords

BETA DEFENSIN 1; BUDESONIDE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; COLECALCIFEROL; CYCLIC AMP; DEXAMETHASONE; FLUTICASONE PROPIONATE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1BETA; LACTOFERRIN; LYSOZYME; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; ANTIMICROBIAL CATIONIC PEPTIDE; BETA DEFENSIN; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; CXCL10 PROTEIN, HUMAN; DEFB1 PROTEIN, HUMAN; GLUCOCORTICOID; POLYINOSINIC POLYCYTIDYLIC ACID;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHIAL EPITHELIAL CELL LINE; CAMP GENE; CATHELICIDIN GENE; CONTROLLED STUDY; CXCL10 GENE; DEFB1 GENE; DOWN REGULATION; DRUG EFFECT; EPITHELIUM CELL; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IL1B GENE; INNATE IMMUNITY; LTF GENE; LZY GENE; MKP 1 GENE; MONOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SLPI GENE; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MACROPHAGE; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION;

ANTIMICROBIAL CATIONIC PEPTIDES; BETA-DEFENSINS; CELL DIFFERENTIATION; CELL LINE; CHEMOKINE CXCL10; CHOLECALCIFEROL; DEXAMETHASONE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1BETA; MACROPHAGES; MIFEPRISTONE; MONOCYTES; MURAMIDASE; POLY I-C; RECEPTORS, GLUCOCORTICOID; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

EID: 84940945095     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.09.001     Document Type: Article

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