메뉴 건너뛰기




Volumn 309, Issue 5, 2015, Pages E450-E457

The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: Clinical efficacy of pulse vs. bolus supply

Author keywords

Amino acids; Anabolic signaling; Muscle full state; Nutrition; Protein synthesis; Skeletal muscle

Indexed keywords

ESSENTIAL AMINO ACID; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MUSCLE PROTEIN; PHENYLALANINE; SONOVUE; CARBON; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

EID: 84940879662     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00112.2015     Document Type: Article
Times cited : (44)

References (56)
  • 1
    • 0019458610 scopus 로고
    • Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man
    • Abumrad NN, Rabin D, Diamond MP, Lacy WW. Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man. Metabolism 30: 936-940, 1981.
    • (1981) Metabolism , vol.30 , pp. 936-940
    • Abumrad, N.N.1    Rabin, D.2    Diamond, M.P.3    Lacy, W.W.4
  • 5
    • 78149304854 scopus 로고    scopus 로고
    • Muscle full effect after oral protein: Time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
    • Atherton PJ, Etheridge T, Watt PW, Wilkinson D, Selby A, Rankin D, Smith K, Rennie MJ. Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling. Am J Clin Nutr 92: 1080-1088, 2010.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1080-1088
    • Atherton, P.J.1    Etheridge, T.2    Watt, P.W.3    Wilkinson, D.4    Selby, A.5    Rankin, D.6    Smith, K.7    Rennie, M.J.8
  • 7
    • 33644681413 scopus 로고    scopus 로고
    • Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases
    • Bell JA, Fujita S, Volpi E, Cadenas JG, Rasmussen BB. Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases. Am J Physiol Endocrinol Metab 289: E999-E1006, 2005.
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Bell, J.A.1    Fujita, S.2    Volpi, E.3    Cadenas, J.G.4    Rasmussen, B.B.5
  • 8
    • 0035871128 scopus 로고    scopus 로고
    • Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids
    • Bohe J, Low JF, Wolfe RR, Rennie MJ. Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids. J Physiol 532: 575-579, 2001.
    • (2001) J Physiol , vol.532 , pp. 575-579
    • Bohe, J.1    Low, J.F.2    Wolfe, R.R.3    Rennie, M.J.4
  • 10
    • 0030897107 scopus 로고    scopus 로고
    • Splanchnic and whole-body leucine kinetics in young and elderly men
    • Boirie Y, Gachon P, Beaufrere B. Splanchnic and whole-body leucine kinetics in young and elderly men. Am J Clin Nutr 65: 489-495, 1997.
    • (1997) Am J Clin Nutr , vol.65 , pp. 489-495
    • Boirie, Y.1    Gachon, P.2    Beaufrere, B.3
  • 13
    • 84864125436 scopus 로고    scopus 로고
    • Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein
    • Casperson SL, Sheffield-Moore M, Hewlings SJ, Paddon-Jones D. Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein. Clin Nutr 31: 512-519, 2012.
    • (2012) Clin Nutr , vol.31 , pp. 512-519
    • Casperson, S.L.1    Sheffield-Moore, M.2    Hewlings, S.J.3    Paddon-Jones, D.4
  • 19
    • 0028915368 scopus 로고
    • Aminoacyl-tRNA synthetases
    • Delarue M. Aminoacyl-tRNA synthetases. Curr Opin Struct Biol 5: 48-55, 1995.
    • (1995) Curr Opin Struct Biol , vol.5 , pp. 48-55
    • Delarue, M.1
  • 21
    • 33749253114 scopus 로고    scopus 로고
    • Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability
    • Fujita S, Rasmussen BB, Cadenas JG, Grady JJ, Volpi E. Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability. Am J Physiol Endocrinol Metab 291: E745-E754, 2006.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Fujita, S.1    Rasmussen, B.B.2    Cadenas, J.G.3    Grady, J.J.4    Volpi, E.5
  • 22
    • 57649232182 scopus 로고    scopus 로고
    • Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
    • Glover EI, Phillips SM, Oates BR, Tang JE, Tarnopolsky MA, Selby A, Smith K, Rennie MJ. Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion. J Physiol 586: 6049-6061, 2008.
    • (2008) J Physiol , vol.586 , pp. 6049-6061
    • Glover, E.I.1    Phillips, S.M.2    Oates, B.R.3    Tang, J.E.4    Tarnopolsky, M.A.5    Selby, A.6    Smith, K.7    Rennie, M.J.8
  • 24
    • 0035744755 scopus 로고    scopus 로고
    • Ageing and muscle: The effects of malnutrition, re-nutrition, and physical exercise
    • Hebuterne X, Bermon S, Schneider SM. Ageing and muscle: the effects of malnutrition, re-nutrition, and physical exercise. Curr Opin Clin Nutr Metab Care 4: 295-300, 2001.
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , pp. 295-300
    • Hebuterne, X.1    Bermon, S.2    Schneider, S.M.3
  • 25
    • 65649152957 scopus 로고    scopus 로고
    • Amino acid transceptors: Gate keepers of nutrient exchange and regulators of nutrient signaling
    • Hundal HS, Taylor PM. Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling. Am J Physiol Endocrinol Metab 296: E603-E613, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Hundal, H.S.1    Taylor, P.M.2
  • 26
    • 0038682500 scopus 로고    scopus 로고
    • Amino acid transporters: Roles in amino acid sensing and signalling in animal cells
    • Hyde R, Taylor PM, Hundal HS. Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem J 373: 1-18, 2003.
    • (2003) Biochem J , vol.373 , pp. 1-18
    • Hyde, R.1    Taylor, P.M.2    Hundal, H.S.3
  • 27
    • 31544482447 scopus 로고    scopus 로고
    • Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids
    • Katsanos CS, Kobayashi H, Sheffield-Moore M, Aarsland A, Wolfe RR. Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr 82: 1065-1073, 2005.
    • (2005) Am J Clin Nutr , vol.82 , pp. 1065-1073
    • Katsanos, C.S.1    Kobayashi, H.2    Sheffield-Moore, M.3    Aarsland, A.4    Wolfe, R.R.5
  • 31
    • 77955280204 scopus 로고    scopus 로고
    • Midarm muscle circumference, physical performance and mortality: Results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    • Landi F, Russo A, Liperoti R, Pahor M, Tosato M, Capoluongo E, Bernabei R, Onder G. Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Clin Nutr 29: 441-447, 2010.
    • (2010) Clin Nutr , vol.29 , pp. 441-447
    • Landi, F.1    Russo, A.2    Liperoti, R.3    Pahor, M.4    Tosato, M.5    Capoluongo, E.6    Bernabei, R.7    Onder, G.8
  • 32
    • 0028857851 scopus 로고
    • Muscle strength and mobility as predictors of survival in 75-84-year-old people
    • Laukkanen P, Heikkinen E, Kauppinen M. Muscle strength and mobility as predictors of survival in 75-84-year-old people. Age Ageing 24: 468-473, 1995.
    • (1995) Age Ageing , vol.24 , pp. 468-473
    • Laukkanen, P.1    Heikkinen, E.2    Kauppinen, M.3
  • 33
    • 84897393588 scopus 로고    scopus 로고
    • Effects of protein in combination with carbohydrate supplements on acute or repeat endurance exercise performance: A systematic review
    • McLellan TM, Pasiakos SM, Lieberman HR. Effects of protein in combination with carbohydrate supplements on acute or repeat endurance exercise performance: a systematic review. Sports Med 44: 535-550, 2014.
    • (2014) Sports Med , vol.44 , pp. 535-550
    • McLellan, T.M.1    Pasiakos, S.M.2    Lieberman, H.R.3
  • 34
    • 84961292080 scopus 로고    scopus 로고
    • A dose- rather than delivery profile-dependent mechanism regulates the “muscle-full” effect in response to oral essential amino acid intake in young men
    • Mitchell WK, Phillips BE, Williams JP, Rankin D, Lund JN, Smith K, Atherton PJ. A dose- rather than delivery profile-dependent mechanism regulates the “muscle-full” effect in response to oral essential amino acid intake in young men. J Nutr 145: 207-214, 2015.
    • (2015) J Nutr , vol.145 , pp. 207-214
    • Mitchell, W.K.1    Phillips, B.E.2    Williams, J.P.3    Rankin, D.4    Lund, J.N.5    Smith, K.6    Atherton, P.J.7
  • 35
    • 85009062737 scopus 로고    scopus 로고
    • Development of a new Sonovue contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding
    • Mitchell WK, Phillips BE, Williams JP, Rankin D, Smith K, Lund JN, Atherton PJ. Development of a new Sonovue contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding. Physiol Rep 1: e00119, 2013.
    • (2013) Physiol Rep , vol.1
    • Mitchell, W.K.1    Phillips, B.E.2    Williams, J.P.3    Rankin, D.4    Smith, K.5    Lund, J.N.6    Atherton, P.J.7
  • 36
    • 84866502856 scopus 로고    scopus 로고
    • Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review
    • Mitchell WK, Williams J, Atherton P, Larvin M, Lund J, Narici M. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front Physiol 3: 260, 2012.
    • (2012) Front Physiol , vol.3 , pp. 260
    • Mitchell, W.K.1    Williams, J.2    Atherton, P.3    Larvin, M.4    Lund, J.5    Narici, M.6
  • 38
    • 84884136929 scopus 로고    scopus 로고
    • Protein redistribution from skeletal muscle to splanchnic tissue on fasting and refeeding in young and older healthy individuals
    • Moreau K, Walrand S, Boirie Y. Protein redistribution from skeletal muscle to splanchnic tissue on fasting and refeeding in young and older healthy individuals. J Am Med Dir Assoc 14: 696-704, 2013.
    • (2013) J am Med Dir Assoc , vol.14 , pp. 696-704
    • Moreau, K.1    Walrand, S.2    Boirie, Y.3
  • 39
    • 0030881763 scopus 로고    scopus 로고
    • Anorexia of aging: Physiologic and pathologic
    • Morley JE. Anorexia of aging: physiologic and pathologic. Am J Clin Nutr 66: 760-773, 1997.
    • (1997) Am J Clin Nutr , vol.66 , pp. 760-773
    • Morley, J.E.1
  • 40
    • 66749157399 scopus 로고    scopus 로고
    • The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats
    • Norton LE, Layman DK, Bunpo P, Anthony TG, Brana DV, Garlick PJ. The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats. J Nutr 139: 1103-1109, 2009.
    • (2009) J Nutr , vol.139 , pp. 1103-1109
    • Norton, L.E.1    Layman, D.K.2    Bunpo, P.3    Anthony, T.G.4    Brana, D.V.5    Garlick, P.J.6
  • 41
    • 84869756324 scopus 로고    scopus 로고
    • Muscular strength in male adolescents and premature death: Cohort study of one million participants
    • Ortega FB, Silventoinen K, Tynelius P, Rasmussen F. Muscular strength in male adolescents and premature death: cohort study of one million participants. BMJ 345: e7279, 2012.
    • (2012) BMJ , vol.345
    • Ortega, F.B.1    Silventoinen, K.2    Tynelius, P.3    Rasmussen, F.4
  • 44
    • 84863141614 scopus 로고    scopus 로고
    • Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise
    • Phillips B, Williams J, Atherton P, Smith K, Hildebrandt W, Rankin D, Greenhaff P, Macdonald I, Rennie MJ. Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise. J Appl Physiol 112: 347-353, 2012.
    • (2012) J Appl Physiol , vol.112 , pp. 347-353
    • Phillips, B.1    Williams, J.2    Atherton, P.3    Smith, K.4    Hildebrandt, W.5    Rankin, D.6    Greenhaff, P.7    Macdonald, I.8    Rennie, M.J.9
  • 45
    • 33746876019 scopus 로고    scopus 로고
    • Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia
    • Rieu I, Balage M, Sornet C, Giraudet C, Pujos E, Grizard J, Mosoni L, Dardevet D. Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. J Physiol 575: 305-315, 2006.
    • (2006) J Physiol , vol.575 , pp. 305-315
    • Rieu, I.1    Balage, M.2    Sornet, C.3    Giraudet, C.4    Pujos, E.5    Grizard, J.6    Mosoni, L.7    Dardevet, D.8
  • 46
    • 0000843250 scopus 로고
    • Nutrient intake by the NSS elderly population
    • edited by Hartz SR, Russell RM, and Rosenberg IH. London: Smith-Gordon
    • Sahyoun NR. Nutrient intake by the NSS elderly population. In: Nutrition in the Elderly: The Boston Nutritional Survey, edited by Hartz SR, Russell RM, and Rosenberg IH. London: Smith-Gordon, 1992, p. 31-44.
    • (1992) Nutrition in The Elderly: The Boston Nutritional Survey , pp. 31-44
    • Sahyoun, N.R.1
  • 48
    • 68849100887 scopus 로고    scopus 로고
    • A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects
    • Symons TB, Sheffield-Moore M, Wolfe RR, Paddon-Jones D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 109: 1582-1586, 2009.
    • (2009) J am Diet Assoc , vol.109 , pp. 1582-1586
    • Symons, T.B.1    Sheffield-Moore, M.2    Wolfe, R.R.3    Paddon-Jones, D.4
  • 49
    • 69749123362 scopus 로고    scopus 로고
    • Ingestion of whey hydrolysate, casein, or soy protein isolate: Effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
    • Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM. Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol 107: 987-992, 2009.
    • (2009) J Appl Physiol , vol.107 , pp. 987-992
    • Tang, J.E.1    Moore, D.R.2    Kujbida, G.W.3    Tarnopolsky, M.A.4    Phillips, S.M.5
  • 52
    • 0034485454 scopus 로고    scopus 로고
    • The response of muscle protein anabolism to combined hyperaminoacidemia and glucoseinduced hyperinsulinemia is impaired in the elderly
    • Volpi E, Mittendorfer B, Rasmussen BB, Wolfe RR. The response of muscle protein anabolism to combined hyperaminoacidemia and glucoseinduced hyperinsulinemia is impaired in the elderly. J Clin Endocrinol Metab 85: 4481-4490, 2000.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4481-4490
    • Volpi, E.1    Mittendorfer, B.2    Rasmussen, B.B.3    Wolfe, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.