-
1
-
-
84897531441
-
SET-NUP214 is a recurrent gammadelta lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL
-
Ben Abdelali, R. et al. SET-NUP214 is a recurrent gammadelta lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL. Blood 123, 1860-1863 (2014).
-
(2014)
Blood
, vol.123
, pp. 1860-1863
-
-
Ben Abdelali, R.1
-
2
-
-
84897507642
-
A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia
-
Tong, W. H. et al. A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia. Blood 123, 2026-2033 (2014).
-
(2014)
Blood
, vol.123
, pp. 2026-2033
-
-
Tong, W.H.1
-
3
-
-
84902080598
-
Activity of the pan-class i phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia
-
Lonetti, A. et al. Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia. Leukemia 28, 1196-1206 (2014).
-
(2014)
Leukemia
, vol.28
, pp. 1196-1206
-
-
Lonetti, A.1
-
4
-
-
84867179824
-
The molecular basis of T cell acute lymphoblastic leukemia
-
Van Vlierberghe, P., Ferrando, A. The molecular basis of T cell acute lymphoblastic leukemia. J. Clin. Invest. 122, 3398-3406 (2012).
-
(2012)
J. Clin. Invest
, vol.122
, pp. 3398-3406
-
-
Van Vlierberghe, P.1
Ferrando, A.2
-
5
-
-
84871821947
-
Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells
-
Zou, J. et al. Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells. J. Hematol. Oncol. 6, 3 (2013).
-
(2013)
J. Hematol. Oncol
, vol.6
, pp. 3
-
-
Zou, J.1
-
6
-
-
33645751939
-
Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis
-
Talora, C. et al. Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis. Blood 107, 3313-3320 (2006).
-
(2006)
Blood
, vol.107
, pp. 3313-3320
-
-
Talora, C.1
-
7
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
Leong, K. G., Karsan, A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 107, 2223-2233 (2006).
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
8
-
-
84856750521
-
Notch induces human T-cell receptor gammadelta+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway
-
Van Coppernolle, S. et al. Notch induces human T-cell receptor gammadelta+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway. Leukemia 26, 127-138 (2012).
-
(2012)
Leukemia
, vol.26
, pp. 127-138
-
-
Van Coppernolle, S.1
-
9
-
-
34250004905
-
Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation
-
Guo, Z. et al. Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation. Blood 109, 5463-5472 (2007).
-
(2007)
Blood
, vol.109
, pp. 5463-5472
-
-
Guo, Z.1
-
10
-
-
84891810705
-
A high Notch pathway activation predicts response to gamma secretase inhibitors in proneural subtype of glioma tumor-initiating cells
-
Saito, N. et al. A high Notch pathway activation predicts response to gamma secretase inhibitors in proneural subtype of glioma tumor-initiating cells. Stem Cells 32, 301-312 (2014).
-
(2014)
Stem Cells
, vol.32
, pp. 301-312
-
-
Saito, N.1
-
11
-
-
84907075560
-
NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma
-
Su, B. H. et al. NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma. Oncotarget 5, 6885-6895 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 6885-6895
-
-
Su, B.H.1
-
12
-
-
84897425195
-
Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer
-
Liu, M. X. et al. Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. Oncotarget 5, 944-958 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 944-958
-
-
Liu, M.X.1
-
13
-
-
84919352811
-
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
-
Durinck, K. et al. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Haematologica 99, 1808-1816 (2014).
-
(2014)
Haematologica
, vol.99
, pp. 1808-1816
-
-
Durinck, K.1
-
14
-
-
84865533113
-
Non-genetic modulation of Notch activity by artificial delivery of Notch intracellular domain into neural stem cells
-
Haupt, S., Borghese, L., Brustle, O., Edenhofer, F. Non-genetic modulation of Notch activity by artificial delivery of Notch intracellular domain into neural stem cells. Stem Cell Rev. 8, 672-684 (2012).
-
(2012)
Stem Cell Rev
, vol.8
, pp. 672-684
-
-
Haupt, S.1
Borghese, L.2
Brustle, O.3
Edenhofer, F.4
-
15
-
-
84910155132
-
Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner
-
Yoon, S. O. et al. Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner. Apoptosis 19, 1616-1626 (2014).
-
(2014)
Apoptosis
, vol.19
, pp. 1616-1626
-
-
Yoon, S.O.1
-
16
-
-
84908379567
-
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia
-
Dail, M. et al. Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia. Nature 513, 512-516 (2014).
-
(2014)
Nature
, vol.513
, pp. 512-516
-
-
Dail, M.1
-
17
-
-
84912070710
-
The Risk-Associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation
-
Pandey, G. K. et al. The Risk-Associated Long Noncoding RNA NBAT-1 Controls Neuroblastoma Progression by Regulating Cell Proliferation and Neuronal Differentiation. Cancer Cell 26, 722-737 (2014).
-
(2014)
Cancer Cell
, vol.26
, pp. 722-737
-
-
Pandey, G.K.1
-
18
-
-
84927933097
-
A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma
-
Tang, J. et al. A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma. Cell Death Dis. 5, e1549 (2014).
-
(2014)
Cell Death Dis
, vol.5
, pp. e1549
-
-
Tang, J.1
-
19
-
-
84883377142
-
A transcriptome-wide atlas of RNP composition reveals diverse classes of mRNAs and lncRNAs
-
Tuck, A. C., Tollervey, D. A transcriptome-wide atlas of RNP composition reveals diverse classes of mRNAs and lncRNAs. Cell 154, 996-1009 (2013).
-
(2013)
Cell
, vol.154
, pp. 996-1009
-
-
Tuck, A.C.1
Tollervey, D.2
-
20
-
-
77955110979
-
Genome-wide computational identification and manual annotation of human long noncoding RNA genes
-
Jia, H. et al. Genome-wide computational identification and manual annotation of human long noncoding RNA genes. RNA 16, 1478-1487 (2010).
-
(2010)
RNA
, vol.16
, pp. 1478-1487
-
-
Jia, H.1
-
21
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn, J. L. et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129, 1311-1323 (2007).
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
-
22
-
-
84873578601
-
Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells
-
Chiang, M. Y., Shestova, O., Xu, L., Aster, J. C., Pear, W. S. Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells. Blood 121, 905-917 (2013).
-
(2013)
Blood
, vol.121
, pp. 905-917
-
-
Chiang, M.Y.1
Shestova, O.2
Xu, L.3
Aster, J.C.4
Pear, W.S.5
-
23
-
-
84899780589
-
Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin
-
Moti, N. et al. Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin. Oncogene 34, 1843-1852 (2014).
-
(2014)
Oncogene
, vol.34
, pp. 1843-1852
-
-
Moti, N.1
-
24
-
-
33645514001
-
A side order of stem cells: The SP phenotype
-
Challen, G. A., Little, M. H. A side order of stem cells: the SP phenotype. Stem Cells 24, 3-12 (2006).
-
(2006)
Stem Cells
, vol.24
, pp. 3-12
-
-
Challen, G.A.1
Little, M.H.2
-
25
-
-
84926099033
-
Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: A multicentre, single-arm, phase 2 study
-
Topp, M. S. et al. Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study. Lancet Oncol. 16, 57-66 (2014).
-
(2014)
Lancet Oncol
, vol.16
, pp. 57-66
-
-
Topp, M.S.1
-
26
-
-
84923343798
-
The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia
-
Schinnerl, D. et al. The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia. Blood 125, 1282-1291 (2014).
-
(2014)
Blood
, vol.125
, pp. 1282-1291
-
-
Schinnerl, D.1
-
27
-
-
84904529279
-
Association of the 3? UTR FOXO3a polymorphism rs4946936 with an increased risk of childhood acute lymphoblastic leukemia in a Chinese population
-
Wang, Y. et al. Association of the 3? UTR FOXO3a polymorphism rs4946936 with an increased risk of childhood acute lymphoblastic leukemia in a Chinese population. Cell. Physiol. Biochem. 34, 325-332 (2014).
-
(2014)
Cell. Physiol. Biochem
, vol.34
, pp. 325-332
-
-
Wang, Y.1
-
28
-
-
84878631939
-
Association of three polymorphisms in ARID5B IKZF1 and CEBPE with the risk of childhood acute lymphoblastic leukemia in a Chinese population
-
Wang, Y. et al. Association of three polymorphisms in ARID5B, IKZF1 and CEBPE with the risk of childhood acute lymphoblastic leukemia in a Chinese population. Gene 524, 203-207 (2013).
-
(2013)
Gene
, vol.524
, pp. 203-207
-
-
Wang, Y.1
-
29
-
-
0025221547
-
Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization
-
Tkachuk, D. C. et al. Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization. Science 250, 559-562 (1990).
-
(1990)
Science
, vol.250
, pp. 559-562
-
-
Tkachuk, D.C.1
-
30
-
-
84924566077
-
Expression and prognostic impact of lncRNAs in acute myeloid leukemia. Proc
-
Garzon, R. et al. Expression and prognostic impact of lncRNAs in acute myeloid leukemia. Proc. Natl. Acad. Sci. USA 111, 18679-18684 (2014).
-
(2014)
Natl. Acad. Sci. USA
, vol.111
, pp. 18679-18684
-
-
Garzon, R.1
-
31
-
-
84906241067
-
Long noncoding RNA associated-competing endogenous RNAs in gastric cancer
-
Xia, T. et al. Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. Sci. Rep. 4, 6088 (2014).
-
(2014)
Sci. Rep
, vol.4
, pp. 6088
-
-
Xia, T.1
-
32
-
-
84923284989
-
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer
-
Chakravarty, D. et al. The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer. Nat. Commun. 5, 5383 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 5383
-
-
Chakravarty, D.1
-
33
-
-
81055140863
-
NcRNA-and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
-
Yang, L. et al. ncRNA-and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell 147, 773-788 (2011).
-
(2011)
Cell
, vol.147
, pp. 773-788
-
-
Yang, L.1
-
34
-
-
84927693630
-
A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B-and T-cell malignancies
-
Ortega, M. et al. A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B-and T-cell malignancies. Leukemia 29, 968-976 (2014).
-
(2014)
Leukemia
, vol.29
, pp. 968-976
-
-
Ortega, M.1
-
35
-
-
0038404519
-
Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells
-
Kumano, K. et al. Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells. Immunity 18, 699-711 (2003).
-
(2003)
Immunity
, vol.18
, pp. 699-711
-
-
Kumano, K.1
-
36
-
-
84881122277
-
In vivo mapping of notch pathway activity in normal and stress hematopoiesis
-
Oh, P. et al. In vivo mapping of notch pathway activity in normal and stress hematopoiesis. Cell Stem Cell 13, 190-204 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 190-204
-
-
Oh, P.1
-
37
-
-
84887242051
-
New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of gamma-secretase inhibitor resistant T-cell acute lymphoblastic leukemia
-
Hales, E. C., Taub, J. W., Matherly, L. H. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of gamma-secretase inhibitor resistant T-cell acute lymphoblastic leukemia. Cell. Signal. 26, 149-161 (2014).
-
(2014)
Cell. Signal
, vol.26
, pp. 149-161
-
-
Hales, E.C.1
Taub, J.W.2
Matherly, L.H.3
-
38
-
-
84905401266
-
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia
-
Trimarchi, T. et al. Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia. Cell 158, 593-606 (2014).
-
(2014)
Cell
, vol.158
, pp. 593-606
-
-
Trimarchi, T.1
|