메뉴 건너뛰기




Volumn 26, Issue 1, 2012, Pages 127-138

Notch induces human T-cell receptor γ δ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

Author keywords

gammadelta T cell; Notch; thymus

Indexed keywords

CD1 ANTIGEN; CD8ALPHA ANTIGEN; NOTCH RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

EID: 84856750521     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.324     Document Type: Article
Times cited : (19)

References (42)
  • 1
    • 3042720708 scopus 로고    scopus 로고
    • Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells
    • Eberl G, Littman DR. Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells. Science 2004; 305: 248-251.
    • (2004) Science , vol.305 , pp. 248-251
    • Eberl, G.1    Littman, D.R.2
  • 2
    • 77958598362 scopus 로고    scopus 로고
    • Alphabeta versus gammadelta fate choice: Counting the T-cell lineages at the branch point
    • Kreslavsky T, Gleimer M, Garbe AI, von Boehmer H. Alphabeta versus gammadelta fate choice: counting the T-cell lineages at the branch point. Immunol Rev 2010; 238: 169-181.
    • (2010) Immunol Rev , vol.238 , pp. 169-181
    • Kreslavsky, T.1    Gleimer, M.2    Garbe, A.I.3    Von Boehmer, H.4
  • 3
    • 77955689094 scopus 로고    scopus 로고
    • Gammadelta TCR ligands and lineage commitment
    • Kreslavsky T, von Boehmer H. Gammadelta TCR ligands and lineage commitment. Semin Immunol 2010; 22: 214-221.
    • (2010) Semin Immunol , vol.22 , pp. 214-221
    • Kreslavsky, T.1    Von Boehmer, H.2
  • 4
    • 17644443445 scopus 로고    scopus 로고
    • T cell receptor γ gene regulatory sequences prevent the function of a novel TCRγ/pTα pre-T cell receptor
    • DOI 10.1016/S1074-7613(00)80576-2
    • Kang J, Fehling HJ, Laplace C, Malissen M, Cado D, Raulet DH. T cell receptor gamma gene regulatory sequences prevent the function of a novel TCRgamma/pTalpha pre-T cell receptor. Immunity 1998; 8: 713-721. (Pubitemid 28294518)
    • (1998) Immunity , vol.8 , Issue.6 , pp. 713-721
    • Kang, J.1    Fehling, H.J.2    Laplace, C.3    Malissen, M.4    Cado, D.5    Raulet, D.H.6
  • 5
    • 0032055406 scopus 로고    scopus 로고
    • The developmental fate of t cells is critically influenced by TCRγδ expression
    • DOI 10.1016/S1074-7613(00)80548-8
    • Kang J, Coles M, Cado D, Raulet DH. The developmental fate of T cells is critically influenced by TCRgammadelta expression. Immunity 1998; 8: 427-438. (Pubitemid 28196797)
    • (1998) Immunity , vol.8 , Issue.4 , pp. 427-438
    • Kang, J.1    Coles, M.2    Cado, D.3    Raulet, D.H.4
  • 6
    • 70349741015 scopus 로고    scopus 로고
    • Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent
    • Lauritsen JP, Wong GW, Lee SY, Lefebvre JM, Ciofani M, Rhodes M et al. Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. Immunity 2009; 31: 565-575.
    • (2009) Immunity , vol.31 , pp. 565-575
    • Lauritsen, J.P.1    Wong, G.W.2    Lee, S.Y.3    Lefebvre, J.M.4    Ciofani, M.5    Rhodes, M.6
  • 7
    • 19344369077 scopus 로고    scopus 로고
    • TCR signal strength influences αβ/γδ lineage fate
    • DOI 10.1016/j.immuni.2005.03.014, PII S1074761305001093
    • Hayes SM, Li L, Love PE. TCR signal strength influences alphabeta/gammadelta lineage fate. Immunity 2005; 22: 583-593. (Pubitemid 40719194)
    • (2005) Immunity , vol.22 , Issue.5 , pp. 583-593
    • Hayes, S.M.1    Li, L.2    Love, P.E.3
  • 8
    • 33745019824 scopus 로고    scopus 로고
    • Differential synergy of Notch and T cell receptor signaling determines αβ versus γδ lineage fate
    • DOI 10.1084/jem.20060474
    • Garbe AI, Krueger A, Gounari F, Zuniga-Pflucker JC, von Boehmer H. Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J Exp Med 2006; 203: 1579-1590. (Pubitemid 43877617)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.6 , pp. 1579-1590
    • Garbe, A.I.1    Krueger, A.2    Gounari, F.3    Zuniga-Pflucker, J.C.4    Von Boehmer, H.5
  • 9
  • 10
    • 0026465914 scopus 로고
    • Analysis of immature (CD4-CD8-) thymic subsets in T-cell receptor alpha beta transgenic mice
    • Wilson A, Pircher H, Ohashi P, MacDonald HR. Analysis of immature (CD4-CD8-) thymic subsets in T-cell receptor alpha beta transgenic mice. Dev Immunol 1992; 2: 85-94.
    • (1992) Dev Immunol , vol.2 , pp. 85-94
    • Wilson, A.1    Pircher, H.2    Ohashi, P.3    MacDonald, H.R.4
  • 11
    • 0031001247 scopus 로고    scopus 로고
    • Notch activity influences the αβ versus γδ T cell lineage decision
    • DOI 10.1016/S0092-8674(00)81929-7
    • Washburn T, Schweighoffer E, Gridley T, Chang D, Fowlkes BJ, Cado D et al. Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell 1997; 88: 833-843. (Pubitemid 27164271)
    • (1997) Cell , vol.88 , Issue.6 , pp. 833-843
    • Washburn, T.1    Schweighoffer, E.2    Gridley, T.3    Chang, D.4    Fowlkes, B.J.5    Cado, D.6    Robey, E.7
  • 12
    • 43549085301 scopus 로고    scopus 로고
    • T cell receptor-instructed -αβ versus γδ lineage commitment revealed by single-cell analysis
    • DOI 10.1084/jem.20072425
    • Kreslavsky T, Garbe AI, Krueger A, von Boehmer H. T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis. J Exp Med 2008; 205: 1173-1186. (Pubitemid 351679691)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.5 , pp. 1173-1186
    • Kreslavsky, T.1    Garbe, A.I.2    Krueger, A.3    Von Boehmer, H.4
  • 14
    • 14344254733 scopus 로고    scopus 로고
    • γδ and αβ T-cell acute lymphoblastic leukemia: Comparision of their clinical and immunophenotypic features
    • Matos DM, Rizzatti EG, Fernandes M, Buccheri V, Falcao RP. Gammadelta and alphabeta T-cell acute lymphoblastic leukemia: comparison of their clinical and immunophenotypic features. Haematologica 2005; 90: 264-266. (Pubitemid 40293295)
    • (2005) Haematologica , vol.90 , Issue.2 , pp. 264-266
    • Matos, D.M.1    Rizzatti, E.G.2    Fernandes, M.3    Buccheri, V.4    Falcao, R.P.5
  • 18
    • 77954118564 scopus 로고    scopus 로고
    • Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells
    • Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M et al. Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. J Immunol 2009; 183: 4859-4870.
    • (2009) J Immunol , vol.183 , pp. 4859-4870
    • Van Coppernolle, S.1    Verstichel, G.2    Timmermans, F.3    Velghe, I.4    Vermijlen, D.5    De Smedt, M.6
  • 19
    • 0029161434 scopus 로고
    • A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC
    • Verfaillie CM, Miller JS. A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC. Blood 1995; 86: 2137-2145.
    • (1995) Blood , vol.86 , pp. 2137-2145
    • Verfaillie, C.M.1    Miller, J.S.2
  • 23
    • 0029086222 scopus 로고
    • Characterization of distinct stages during the differentiation of human CD69+CD3+ thymocytes and identification of thymic emigrants
    • Vanhecke D, Leclercq G, Plum J, Vandekerckhove B. Characterization of distinct stages during the differentiation of human CD69+CD3+ thymocytes and identification of thymic emigrants. J Immunol 1995; 155: 1862-1872.
    • (1995) J Immunol , vol.155 , pp. 1862-1872
    • Vanhecke, D.1    Leclercq, G.2    Plum, J.3    Vandekerckhove, B.4
  • 24
    • 0025873417 scopus 로고
    • Functional and phenotypic differences between CD4+ and CD4-T cell receptor-gamma delta clones from peripheral blood
    • Spits H, Paliard X, Vandekerckhove Y, van Vlasselaer P, de Vries JE. Functional and phenotypic differences between CD4+ and CD4-T cell receptor-gamma delta clones from peripheral blood. J Immunol 1991; 147: 1180-1188.
    • (1991) J Immunol , vol.147 , pp. 1180-1188
    • Spits, H.1    Paliard, X.2    Vandekerckhove, Y.3    Van Vlasselaer, P.4    De Vries, J.E.5
  • 25
    • 30444454357 scopus 로고    scopus 로고
    • Developmental and molecular characterization of emerging β- and γδ-selected pre-T cells in the adult mouse thymus
    • DOI 10.1016/j.immuni.2005.11.012, PII S1074761305004073
    • Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV. Developmental and molecular characterization of emerging beta-and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity 2006; 24: 53-64. (Pubitemid 43077200)
    • (2006) Immunity , vol.24 , Issue.1 , pp. 53-64
    • Taghon, T.1    Yui, M.A.2    Pant, R.3    Diamond, R.A.4    Rothenberg, E.V.5
  • 26
    • 65349103035 scopus 로고    scopus 로고
    • Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development
    • Taghon T, Van de Walle I, De Smet G, De Smedt M, Leclercq G, Vandekerckhove B et al. Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development. Blood 2009; 113: 3254-3263.
    • (2009) Blood , vol.113 , pp. 3254-3263
    • Taghon, T.1    Van De Walle, I.2    De Smet, G.3    De Smedt, M.4    Leclercq, G.5    Vandekerckhove, B.6
  • 28
    • 63849086285 scopus 로고    scopus 로고
    • An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells
    • Van de Walle I, De Smet G, De Smedt M, Vandekerckhove B, Leclercq G, Plum J et al. An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells. Blood 2009; 113: 2988-2998.
    • (2009) Blood , vol.113 , pp. 2988-2998
    • Van De Walle, I.1    De Smet, G.2    De Smedt, M.3    Vandekerckhove, B.4    Leclercq, G.5    Plum, J.6
  • 29
    • 0027327781 scopus 로고
    • Development of T cell receptor-γδ cells: Phenotypic and functional correlations of T cell receptor-γδ thymocyte maturation
    • Tatsumi Y, Pena JC, Matis L, Deluca D, Bluestone JA. Development of T cell receptor-gamma delta cells. Phenotypic and functional correlations of T cell receptor-gamma delta thymocyte maturation. J Immunol 1993; 151: 3030-3041. (Pubitemid 23282615)
    • (1993) Journal of Immunology , vol.151 , Issue.6 , pp. 3030-3041
    • Tatsumi, Y.1    Pena, J.C.2    Matis, L.3    Deluca, D.4    Bluestone, J.A.5
  • 30
    • 0032402305 scopus 로고    scopus 로고
    • A limited role for β-selection during γδ T cell development
    • Wilson A, MacDonald HR. A limited role for beta-selection during gamma delta T cell development. J Immunol 1998; 161: 5851-5854. (Pubitemid 28535950)
    • (1998) Journal of Immunology , vol.161 , Issue.11 , pp. 5851-5854
    • Wilson, A.1    MacDonald, H.R.2
  • 31
    • 31144455406 scopus 로고    scopus 로고
    • Human αβ and γδ thymocyte development: TCR gene rearrangements, intracellular TCRβ expression, and γδ developmental potential - Differences between men and mice
    • Joachims ML, Chain JL, Hooker SW, Knott-Craig CJ, Thompson LF. Human alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potentialFdifferences between men and mice. J Immunol 2006; 176: 1543-1552. (Pubitemid 43134298)
    • (2006) Journal of Immunology , vol.176 , Issue.3 , pp. 1543-1552
    • Joachims, M.L.1    Chain, J.L.2    Hooker, S.W.3    Knott-Craig, C.J.4    Thompson, L.F.5
  • 32
    • 77954656254 scopus 로고    scopus 로고
    • Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice
    • Lee SY, Stadanlick J, Kappes DJ, Wiest DL. Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice. Semin Immunol 2010; 22: 237-246.
    • (2010) Semin Immunol , vol.22 , pp. 237-246
    • Lee, S.Y.1    Stadanlick, J.2    Kappes, D.J.3    Wiest, D.L.4
  • 33
    • 33646671945 scopus 로고    scopus 로고
    • E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
    • DOI 10.1084/jem.20060268
    • Ikawa T, Kawamoto H, Goldrath AW, Murre C. E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment. J Exp Med 2006; 203: 1329-1342. (Pubitemid 43736601)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.5 , pp. 1329-1342
    • Ikawa, T.1    Kawamoto, H.2    Goldrath, A.W.3    Murre, C.4
  • 34
    • 33745014890 scopus 로고    scopus 로고
    • Stage-Specific and Differential Notch Dependency at the αβ and γδ T Lineage Bifurcation
    • DOI 10.1016/j.immuni.2006.05.010, PII S1074761306002962
    • Ciofani M, Knowles GC, Wiest DL, von Boehmer H, Zuniga-Pflucker JC. Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. Immunity 2006; 25: 105-116. (Pubitemid 44066824)
    • (2006) Immunity , vol.25 , Issue.1 , pp. 105-116
    • Ciofani, M.1    Knowles, G.C.2    Wiest, D.L.3    Von Boehmer, H.4    Zuniga-Pflucker, J.C.5
  • 35
    • 2442522357 scopus 로고    scopus 로고
    • Regulation of αβ/γδ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
    • DOI 10.1016/S1074-7613(04)00109-8, PII S1074761304001098
    • Tanigaki K, Tsuji M, Yamamoto N, Han H, Tsukada J, Inoue H et al. Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 2004; 20: 611-622. (Pubitemid 38638130)
    • (2004) Immunity , vol.20 , Issue.5 , pp. 611-622
    • Tanigaki, K.1    Tsuji, M.2    Yamamoto, N.3    Han, H.4    Tsukada, J.5    Inoue, H.6    Kubo, M.7    Honjo, T.8
  • 36
    • 33744977004 scopus 로고    scopus 로고
    • Interplay between RORγt, Egr3, and E Proteins Controls Proliferation in Response to Pre-TCR Signals
    • DOI 10.1016/j.immuni.2006.03.023, PII S1074761306002615
    • Xi H, Schwartz R, Engel I, Murre C, Kersh GJ. Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. Immunity 2006; 24: 813-826. (Pubitemid 43867364)
    • (2006) Immunity , vol.24 , Issue.6 , pp. 813-826
    • Xi, H.1    Schwartz, R.2    Engel, I.3    Murre, C.4    Kersh, G.J.5
  • 39
    • 42649092113 scopus 로고    scopus 로고
    • Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal γδ T cells
    • DOI 10.1038/ng.108, PII NG108
    • Boyden LM, Lewis JM, Barbee SD, Bas A, Girardi M, Hayday AC et al. Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat Genet 2008; 40: 656-662. (Pubitemid 351601202)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 656-662
    • Boyden, L.M.1    Lewis, J.M.2    Barbee, S.D.3    Bas, A.4    Girardi, M.5    Hayday, A.C.6    Tigelaar, R.E.7    Lifton, R.P.8
  • 40
    • 46749113368 scopus 로고    scopus 로고
    • Thymic selection determines gammadelta T cell effector fate: Antigennaive cells make interleukin-17 and antigen-experienced cells make interferon gamma
    • Jensen KD, Su X, Shin S, Li L, Youssef S, Yamasaki S et al. Thymic selection determines gammadelta T cell effector fate: antigennaive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity 2008; 29: 90-100.
    • (2008) Immunity , vol.29 , pp. 90-100
    • Jensen, K.D.1    Su, X.2    Shin, S.3    Li, L.4    Youssef, S.5    Yamasaki, S.6
  • 42
    • 79955972801 scopus 로고    scopus 로고
    • Jagged2 acts as a delta-like Notch ligand during early hematopoietic cell fate decisions
    • Van de Walle I, De Smet G, Gartner M, De Smedt M, Waegemans E, Vandekerckhove B et al. Jagged2 acts as a delta-like Notch ligand during early hematopoietic cell fate decisions. Blood 2011; 117: 4449-4459.
    • (2011) Blood , vol.117 , pp. 4449-4459
    • Van De Walle, I.1    De Smet, G.2    Gartner, M.3    De Smedt, M.4    Waegemans, E.5    Vandekerckhove, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.