메뉴 건너뛰기




Volumn 24, Issue 9, 2015, Pages 925-931

Levosimendan Improves Neurological Outcome in a Swine Model of Asphyxial Cardiac Arrest

Author keywords

Asphyxia; Cardiac arrest; Cardiopulmonary resuscitation; Levosimendan; Neurological outcome

Indexed keywords

ADRENALIN; LEVOSIMENDAN; PLACEBO; HYDRAZONE DERIVATIVE; PYRIDAZINE DERIVATIVE; SIMENDAN;

EID: 84940795507     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2015.02.024     Document Type: Article
Times cited : (6)

References (42)
  • 1
    • 84889648877 scopus 로고    scopus 로고
    • Differences of postresuscitation myocardial dysfunction in ventricular fibrillation versus asphyxiation
    • Wu C.J., Li C.S., Zhang Y., Yang J., Yin Q., Hang C.C. Differences of postresuscitation myocardial dysfunction in ventricular fibrillation versus asphyxiation. Am J Emerg Med 2013, 31:1690-1696.
    • (2013) Am J Emerg Med , vol.31 , pp. 1690-1696
    • Wu, C.J.1    Li, C.S.2    Zhang, Y.3    Yang, J.4    Yin, Q.5    Hang, C.C.6
  • 4
    • 0035797840 scopus 로고    scopus 로고
    • Developing a vasopressor combination in a pig model of adult asphyxial cardiac arrest
    • Mayr VD1, Wenzel V., Voelckel W.G., Krismer A.C., Mueller T., Lurie K.G., et al. Developing a vasopressor combination in a pig model of adult asphyxial cardiac arrest. Circulation 2001, 104:1651-1656.
    • (2001) Circulation , vol.104 , pp. 1651-1656
    • Mayr, V.D.1    Wenzel, V.2    Voelckel, W.G.3    Krismer, A.C.4    Mueller, T.5    Lurie, K.G.6
  • 5
    • 84857992858 scopus 로고    scopus 로고
    • Post-cardiac arrest brain injury: pathophysiology and treatment
    • Chalkias A., Xanthos T. Post-cardiac arrest brain injury: pathophysiology and treatment. J Neurol Sci 2012, 315:1-8.
    • (2012) J Neurol Sci , vol.315 , pp. 1-8
    • Chalkias, A.1    Xanthos, T.2
  • 6
    • 0037142946 scopus 로고    scopus 로고
    • Steering Committee and Investigators of the Levosimendan Infusion versus Dobutamine (LIDO) Study. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low output heart failure (the LIDO study): a randomized double-blind trial
    • Follath F., Cleland J.G., Just H., Papp J.G., Scholz H., Peuhkurinen K., et al. Steering Committee and Investigators of the Levosimendan Infusion versus Dobutamine (LIDO) Study. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low output heart failure (the LIDO study): a randomized double-blind trial. Lancet 2002, 360:196-202.
    • (2002) Lancet , vol.360 , pp. 196-202
    • Follath, F.1    Cleland, J.G.2    Just, H.3    Papp, J.G.4    Scholz, H.5    Peuhkurinen, K.6
  • 7
    • 0034739460 scopus 로고    scopus 로고
    • Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Study Investigators
    • Slawsky M.T., Colucci W.S., Gottlieb S.S., Greenberg B.H., Haeusslein E., Hare J., et al. Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Study Investigators. Circulation 2000, 102:2222-2227.
    • (2000) Circulation , vol.102 , pp. 2222-2227
    • Slawsky, M.T.1    Colucci, W.S.2    Gottlieb, S.S.3    Greenberg, B.H.4    Haeusslein, E.5    Hare, J.6
  • 8
    • 0034669441 scopus 로고    scopus 로고
    • Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure
    • Nieminen M.S., Akkila J., Hasenfuss G., Kleber F.X., Lehtonen L.A., Mitrovic V., et al. Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure. J Am Coll Cardiol 2000, 36:1903-1912.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1903-1912
    • Nieminen, M.S.1    Akkila, J.2    Hasenfuss, G.3    Kleber, F.X.4    Lehtonen, L.A.5    Mitrovic, V.6
  • 10
    • 34547829784 scopus 로고    scopus 로고
    • Levosimendan improves the initial outcome of cardiopulmonary resuscitation in a swine model of cardiac arrest
    • Koudouna E., Xanthos T., Bassiakou E., Goulas S., Lelovas P., Papadimitriou D., et al. Levosimendan improves the initial outcome of cardiopulmonary resuscitation in a swine model of cardiac arrest. Acta Anaesthesiol Scand 2007, 51:1123-1129.
    • (2007) Acta Anaesthesiol Scand , vol.51 , pp. 1123-1129
    • Koudouna, E.1    Xanthos, T.2    Bassiakou, E.3    Goulas, S.4    Lelovas, P.5    Papadimitriou, D.6
  • 12
    • 84869462096 scopus 로고    scopus 로고
    • Epinephrine, vasopressin, and nitroglycerin improve neurologic outcome in porcine asphyxial cardiac arrest
    • Varvarousi G., Goulas S., Agrogiannis G., Valsamakis N., Iliopoulos D., Perrea D., et al. Epinephrine, vasopressin, and nitroglycerin improve neurologic outcome in porcine asphyxial cardiac arrest. Am J Emerg Med 2012, 30:1549-1554.
    • (2012) Am J Emerg Med , vol.30 , pp. 1549-1554
    • Varvarousi, G.1    Goulas, S.2    Agrogiannis, G.3    Valsamakis, N.4    Iliopoulos, D.5    Perrea, D.6
  • 13
    • 34547558261 scopus 로고    scopus 로고
    • Cardiopulmonary arrest and resuscitation in Landrace/Large White swine: a research model
    • Xanthos T., Lelovas P., Vlachos I., Tsirikos-Karapanos N., Kouskouni E., Perrea D., et al. Cardiopulmonary arrest and resuscitation in Landrace/Large White swine: a research model. Lab Anim 2007, 41:353-362.
    • (2007) Lab Anim , vol.41 , pp. 353-362
    • Xanthos, T.1    Lelovas, P.2    Vlachos, I.3    Tsirikos-Karapanos, N.4    Kouskouni, E.5    Perrea, D.6
  • 14
    • 78049478848 scopus 로고    scopus 로고
    • European resuscitation council guidelines for resuscitation 2010. Section 4. Adult advanced life support
    • Deakin C.D., Nolan J.P., Soar J., Sunde K., Koster R.W., Smith G.B., et al. European resuscitation council guidelines for resuscitation 2010. Section 4. Adult advanced life support. Resuscitation 2010, 81:1305-1352.
    • (2010) Resuscitation , vol.81 , pp. 1305-1352
    • Deakin, C.D.1    Nolan, J.P.2    Soar, J.3    Sunde, K.4    Koster, R.W.5    Smith, G.B.6
  • 15
    • 36048959159 scopus 로고    scopus 로고
    • Baseline hemodynamics in anesthetized Landrace-Large White swine: reference values for research in cardiac arrest and cardiopulmonary resuscitation models
    • Xanthos T., Bassiakou E., Koudouna E., Tsirikos-Karapanos N., Lelovas P., Papadimitriou D., et al. Baseline hemodynamics in anesthetized Landrace-Large White swine: reference values for research in cardiac arrest and cardiopulmonary resuscitation models. J Am Assoc Lab Anim Sci 2007, 46:21-25.
    • (2007) J Am Assoc Lab Anim Sci , vol.46 , pp. 21-25
    • Xanthos, T.1    Bassiakou, E.2    Koudouna, E.3    Tsirikos-Karapanos, N.4    Lelovas, P.5    Papadimitriou, D.6
  • 16
    • 27644461757 scopus 로고    scopus 로고
    • Preanaesthesia, anesthesia, analgesia and euthanasia
    • Academic Press, New York, J.G. Fox, L.C. Anderson, F.M. Loew, F.W. Quimby (Eds.)
    • Swindle M.M., Volger G.A., Fulton L.K., Marini R.P., Popilskis S. Preanaesthesia, anesthesia, analgesia and euthanasia. Laboratory Animal Medicine 2002, 955-1003. Academic Press, New York. Second Edition. J.G. Fox, L.C. Anderson, F.M. Loew, F.W. Quimby (Eds.).
    • (2002) Laboratory Animal Medicine , pp. 955-1003
    • Swindle, M.M.1    Volger, G.A.2    Fulton, L.K.3    Marini, R.P.4    Popilskis, S.5
  • 18
    • 79956146927 scopus 로고    scopus 로고
    • Correlations between hemodynamic, oxygenation and tissue perfusion parameters during asphyxial cardiac arrest and resuscitation in a pediatric animal model
    • López-Herce J., Fernández B., Urbano J., Mencía S., Solana M.J., Del Castillo J., et al. Correlations between hemodynamic, oxygenation and tissue perfusion parameters during asphyxial cardiac arrest and resuscitation in a pediatric animal model. Resuscitation 2011, 82:755-759.
    • (2011) Resuscitation , vol.82 , pp. 755-759
    • López-Herce, J.1    Fernández, B.2    Urbano, J.3    Mencía, S.4    Solana, M.J.5    Del Castillo, J.6
  • 19
    • 0030608872 scopus 로고    scopus 로고
    • Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes
    • Yokoshiki H., Katsube Y., Sunagawa M., Sperelakis N. Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes. Eur J Pharmacol 1997, 333:249-259.
    • (1997) Eur J Pharmacol , vol.333 , pp. 249-259
    • Yokoshiki, H.1    Katsube, Y.2    Sunagawa, M.3    Sperelakis, N.4
  • 20
    • 0035088001 scopus 로고    scopus 로고
    • Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels
    • Kaheinen P., Pollesello P., Levijoki J., Haikala H. Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels. J Cardiovasc Pharmacol 2001, 37:367-374.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 367-374
    • Kaheinen, P.1    Pollesello, P.2    Levijoki, J.3    Haikala, H.4
  • 21
    • 33745607928 scopus 로고    scopus 로고
    • The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arterioles
    • Erdei N., Papp Z., Pollesello P., Edes I., Bagi Z. The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arterioles. Br J Pharmacol 2006, 148:696-702.
    • (2006) Br J Pharmacol , vol.148 , pp. 696-702
    • Erdei, N.1    Papp, Z.2    Pollesello, P.3    Edes, I.4    Bagi, Z.5
  • 22
    • 80054714648 scopus 로고    scopus 로고
    • Asphyxial cardiac arrest, resuscitation and neurological outcome in a Landrace/Large-White swine model
    • Varvarousi G., Xanthos T., Lappas T., Lekka N., Goulas S., Dontas I., et al. Asphyxial cardiac arrest, resuscitation and neurological outcome in a Landrace/Large-White swine model. Lab Anim 2011, 45:184-190.
    • (2011) Lab Anim , vol.45 , pp. 184-190
    • Varvarousi, G.1    Xanthos, T.2    Lappas, T.3    Lekka, N.4    Goulas, S.5    Dontas, I.6
  • 23
  • 24
    • 84655167884 scopus 로고    scopus 로고
    • Pathophysiology and pathogenesis of post-resuscitation myocardial stunning
    • Chalkias A., Xanthos T. Pathophysiology and pathogenesis of post-resuscitation myocardial stunning. Heart Fail Rev 2012, 17:117-128.
    • (2012) Heart Fail Rev , vol.17 , pp. 117-128
    • Chalkias, A.1    Xanthos, T.2
  • 25
    • 78650368315 scopus 로고    scopus 로고
    • Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study
    • Morelli A., Donati A., Ertmer C., Rehberg S., Lange M., Orecchioni A., et al. Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study. Crit Care 2010, 14:R232.
    • (2010) Crit Care , vol.14 , pp. R232
    • Morelli, A.1    Donati, A.2    Ertmer, C.3    Rehberg, S.4    Lange, M.5    Orecchioni, A.6
  • 26
  • 27
    • 0029613261 scopus 로고
    • Mechanisms of action of calcium-sensitizing drugs
    • Haikala H., Linden I.B. Mechanisms of action of calcium-sensitizing drugs. J Cardiovasc Pharmacol 1995, 26:10-19.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 10-19
    • Haikala, H.1    Linden, I.B.2
  • 28
    • 0028172183 scopus 로고
    • Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study
    • Pollesello P., Ovaska M., Kaivola J., Tilgmann C., Lundström K., Kalkkinen N., et al. Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study. J Biol Chem 1994, 69:28584-28590.
    • (1994) J Biol Chem , vol.69 , pp. 28584-28590
    • Pollesello, P.1    Ovaska, M.2    Kaivola, J.3    Tilgmann, C.4    Lundström, K.5    Kalkkinen, N.6
  • 29
    • 9444292903 scopus 로고    scopus 로고
    • The contractile apparatus as a target for drugs against heart failure: interaction of levosimendan, a calcium sensitiser, with cardiac troponin c
    • Sorsa T., Pollesello P., Solaro R.J. The contractile apparatus as a target for drugs against heart failure: interaction of levosimendan, a calcium sensitiser, with cardiac troponin c. Mol Cell Biochem 2004, 266:87-107.
    • (2004) Mol Cell Biochem , vol.266 , pp. 87-107
    • Sorsa, T.1    Pollesello, P.2    Solaro, R.J.3
  • 30
    • 45149116658 scopus 로고    scopus 로고
    • Calcium sensitizing in sepsis: is levosimendan on the right path?
    • Morelli A., Ertmer C., Westphal M. Calcium sensitizing in sepsis: is levosimendan on the right path?. Crit Care Med 2008, 36:1981-1982.
    • (2008) Crit Care Med , vol.36 , pp. 1981-1982
    • Morelli, A.1    Ertmer, C.2    Westphal, M.3
  • 32
    • 34548218149 scopus 로고    scopus 로고
    • Levosimendan in septic shock: a case series
    • Powell B.P., De Keulenaer B.L. Levosimendan in septic shock: a case series. Br J Anaesth 2007, 99:447-448.
    • (2007) Br J Anaesth , vol.99 , pp. 447-448
    • Powell, B.P.1    De Keulenaer, B.L.2
  • 34
    • 84901488573 scopus 로고    scopus 로고
    • Effects of levosimendan on hemodynamics, local cerebral blood flow, neuronal injury, and neuroinflammation after asphyctic cardiac arrest in rats
    • Kelm R.F., Wagenführer J., Bauer H., Schmidtmann I., Engelhard K., Noppens R.R. Effects of levosimendan on hemodynamics, local cerebral blood flow, neuronal injury, and neuroinflammation after asphyctic cardiac arrest in rats. Crit Care Med 2014, 42:e410-e419.
    • (2014) Crit Care Med , vol.42 , pp. e410-e419
    • Kelm, R.F.1    Wagenführer, J.2    Bauer, H.3    Schmidtmann, I.4    Engelhard, K.5    Noppens, R.R.6
  • 35
    • 14944348020 scopus 로고    scopus 로고
    • Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction
    • Huang L., Weil M.H., Tang W., Sun S., Wang J. Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction. Crit Care Med 2005, 33:487-491.
    • (2005) Crit Care Med , vol.33 , pp. 487-491
    • Huang, L.1    Weil, M.H.2    Tang, W.3    Sun, S.4    Wang, J.5
  • 36
    • 0029558280 scopus 로고
    • Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction
    • Lilleberg J., Sundberg S., Nieminen M.S. Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction. J Cardiovasc Pharmacol 1995, 26:63-69.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 63-69
    • Lilleberg, J.1    Sundberg, S.2    Nieminen, M.S.3
  • 37
    • 33846082231 scopus 로고    scopus 로고
    • Duration of the haemodynamic action of a 24-h infusion of levosimendan in patients with congestive heart failure
    • Lilleberg J., Laine M., Palkama T., Kivikko M., Pohjanjousi P., Kupari M. Duration of the haemodynamic action of a 24-h infusion of levosimendan in patients with congestive heart failure. Eur J Heart Fail 2007, 9:75-82.
    • (2007) Eur J Heart Fail , vol.9 , pp. 75-82
    • Lilleberg, J.1    Laine, M.2    Palkama, T.3    Kivikko, M.4    Pohjanjousi, P.5    Kupari, M.6
  • 38
    • 33846107921 scopus 로고    scopus 로고
    • Epidemiology, trends and outcome of out-of-hospital cardiac arrest of non-cardiac origin
    • Hess E.P., Campbell R.L., White R.D. Epidemiology, trends and outcome of out-of-hospital cardiac arrest of non-cardiac origin. Resuscitation 2007, 72:200-206.
    • (2007) Resuscitation , vol.72 , pp. 200-206
    • Hess, E.P.1    Campbell, R.L.2    White, R.D.3
  • 39
    • 27944479076 scopus 로고    scopus 로고
    • Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledge
    • CanAm Pediatric Cardiac Arrest Investigators
    • Donoghue A.J., Nadkarni V., Berg R.A., Osmond M.H., Wells G., Nesbitt L., et al. Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledge. Ann Emerg Med 2005, 46:512-522. CanAm Pediatric Cardiac Arrest Investigators.
    • (2005) Ann Emerg Med , vol.46 , pp. 512-522
    • Donoghue, A.J.1    Nadkarni, V.2    Berg, R.A.3    Osmond, M.H.4    Wells, G.5    Nesbitt, L.6
  • 40
    • 0036890677 scopus 로고    scopus 로고
    • Evaluation of LUCAS, a new device for automatic mechanical compression and active decompression resuscitation
    • Steen S., Liao Q., Pierre L., Paskevicius A., Sjöberg T. Evaluation of LUCAS, a new device for automatic mechanical compression and active decompression resuscitation. Resuscitation 2002, 55:285-299.
    • (2002) Resuscitation , vol.55 , pp. 285-299
    • Steen, S.1    Liao, Q.2    Pierre, L.3    Paskevicius, A.4    Sjöberg, T.5
  • 41
    • 84881141441 scopus 로고    scopus 로고
    • Levosimendan limits reperfusion injury in a rat middle cerebral artery occlusion (MCAO) model
    • Hein M., Zoremba N., Bleilevens C., Bruells C., Rossaint R., Roehl A.B. Levosimendan limits reperfusion injury in a rat middle cerebral artery occlusion (MCAO) model. BMC Neurol 2013, 13:106.
    • (2013) BMC Neurol , vol.13 , pp. 106
    • Hein, M.1    Zoremba, N.2    Bleilevens, C.3    Bruells, C.4    Rossaint, R.5    Roehl, A.B.6
  • 42
    • 21044443575 scopus 로고    scopus 로고
    • Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression
    • Morelli A., De Castro S., Teboul J.L., Singer M., Rocco M., Conti G., et al. Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive Care Med 2005, 31:638-644.
    • (2005) Intensive Care Med , vol.31 , pp. 638-644
    • Morelli, A.1    De Castro, S.2    Teboul, J.L.3    Singer, M.4    Rocco, M.5    Conti, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.