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Volumn 333, Issue 2-3, 1997, Pages 249-259

Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes

Author keywords

K+ channel; K+ channel ATP sensitive; Levosimendan; Mesenteric artery; Patch clamp technique; Rat

Indexed keywords

GLIBENCLAMIDE; LEVOSIMENDAN; POTASSIUM CHANNEL; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ANTIDIABETIC AGENT; CHARYBDOTOXIN; ENZYME INHIBITOR; HYDRAZONE DERIVATIVE; PYRIDAZINE DERIVATIVE; SIMENDAN; VASODILATOR AGENT;

EID: 0030608872     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01108-4     Document Type: Article
Times cited : (289)

References (59)
  • 2
    • 0027305489 scopus 로고
    • K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells
    • Beech D.J., Zhang H., Nakao K., Bolton T.B. K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells. Br. J. Pharmacol. 110:1993;573-582.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 573-582
    • Beech, D.J.1    Zhang, H.2    Nakao, K.3    Bolton, T.B.4
  • 3
    • 0027268048 scopus 로고
    • Single channel and whole-cell K-currents evoked by levocromakalim in smooth muscle cells from the rabbit portal vein
    • Beech D.J., Zhang H., Nakao K., Bolton T.B. Single channel and whole-cell K-currents evoked by levocromakalim in smooth muscle cells from the rabbit portal vein. Br. J. Pharmacol. 110:1993;583-590.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 583-590
    • Beech, D.J.1    Zhang, H.2    Nakao, K.3    Bolton, T.B.4
  • 4
    • 0026554833 scopus 로고
    • + channels regulate resting potential of pulmonary arterial smooth muscle cells
    • + channels regulate resting potential of pulmonary arterial smooth muscle cells. Am. J. Physiol. 262:1992;H916-H920.
    • (1992) Am. J. Physiol. , vol.262
    • Clapp, L.H.1    Gurney, A.M.2
  • 7
    • 0027366619 scopus 로고
    • Adenosine-activated potassium current in smooth muscle cells isolated from the pig coronary artery
    • Dart C., Standen N.B. Adenosine-activated potassium current in smooth muscle cells isolated from the pig coronary artery. J. Physiol. London. 471:1993;767-786.
    • (1993) J. Physiol. London , vol.471 , pp. 767-786
    • Dart, C.1    Standen, N.B.2
  • 8
    • 0028919992 scopus 로고
    • + channels by hypoxia in smooth muscle cells isolated from the pig coronary artery
    • + channels by hypoxia in smooth muscle cells isolated from the pig coronary artery. J. Physiol. London. 483:1995;29-39.
    • (1995) J. Physiol. London , vol.483 , pp. 29-39
    • Dart, C.1    Standen, N.B.2
  • 10
    • 0026607830 scopus 로고
    • Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery
    • Eckman D.M., Frankovich J.D., Keef K.D. Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery. Br. J. Pharmacol. 106:1992;9-16.
    • (1992) Br. J. Pharmacol. , vol.106 , pp. 9-16
    • Eckman, D.M.1    Frankovich, J.D.2    Keef, K.D.3
  • 12
    • 0027409532 scopus 로고
    • The pharmacology of ATP-sensitive potassium channels
    • Edwards G., Weston A.H. The pharmacology of ATP-sensitive potassium channels. Annu. Rev. Pharmacol. Toxicol. 33:1993;597-637.
    • (1993) Annu. Rev. Pharmacol. Toxicol. , vol.33 , pp. 597-637
    • Edwards, G.1    Weston, A.H.2
  • 13
    • 0027490618 scopus 로고
    • + channel and enhanced vascular smooth muscle relaxation in genetically hypertensive rats
    • + channel and enhanced vascular smooth muscle relaxation in genetically hypertensive rats. J. Hypertens. 11:1993;1067-1072.
    • (1993) J. Hypertens. , vol.11 , pp. 1067-1072
    • Furspan, P.B.1    Webb, R.C.2
  • 15
    • 0029097331 scopus 로고
    • Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs
    • Harkin C.P., Pagel P.S., Tessmer J.P., Warltier D.C. Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs. J. Cardiovasc. Pharmacol. 26:1995;179-188.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , pp. 179-188
    • Harkin, C.P.1    Pagel, P.S.2    Tessmer, J.P.3    Warltier, D.C.4
  • 21
    • 0021892605 scopus 로고
    • Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells
    • Kakei M., Noma A., Shibasaki T. Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J. Physiol. London. 363:1985;441-462.
    • (1985) J. Physiol. London , vol.363 , pp. 441-462
    • Kakei, M.1    Noma, A.2    Shibasaki, T.3
  • 23
    • 0029973379 scopus 로고    scopus 로고
    • Differential sensitivity of venular and arteriolar α-adrenergic receptor constriction to inhibition by hypoxia. Role of receptor subtype and coupling heterogeneity
    • Leech C.J., Faber J.E. Differential sensitivity of venular and arteriolar α-adrenergic receptor constriction to inhibition by hypoxia. Role of receptor subtype and coupling heterogeneity. Circ. Res. 78:1996;1064-1074.
    • (1996) Circ. Res. , vol.78 , pp. 1064-1074
    • Leech, C.J.1    Faber, J.E.2
  • 24
    • 0029558280 scopus 로고
    • Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction
    • Lilleberg J., Sundberg S., Nieminen M.S. Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction. J. Cardiovasc. Pharmacol. 26 (Suppl. 1):1995;S63-S69.
    • (1995) J. Cardiovasc. Pharmacol. , vol.261
    • Lilleberg, J.1    Sundberg, S.2    Nieminen, M.S.3
  • 27
    • 0027212939 scopus 로고
    • + channels by cyclic AMP-dependent protein kinase in cultured smooth muscle cells of porcine coronary artery
    • + channels by cyclic AMP-dependent protein kinase in cultured smooth muscle cells of porcine coronary artery. Biochem. Biophys. Res. Commun. 193:1993;240-247.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 240-247
    • Miyoshi, H.1    Nakaya, Y.2
  • 29
    • 0029053514 scopus 로고
    • Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels
    • Murphy M.E., Brayden J.E. Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels. J. Physiol. London. 486:1995;47-58.
    • (1995) J. Physiol. London , vol.486 , pp. 47-58
    • Murphy, M.E.1    Brayden, J.E.2
  • 31
    • 0029982656 scopus 로고    scopus 로고
    • Coronary effects of diadenosine tetraphosphate resemble those of adenosine in anesthetized pigs: Involvement of ATP-sensitive potassium channels
    • Nakae I., Takahashi M., Takaoka A., Liu Q., Matsumoto T., Amano M., Sekine A., Nakajima H., Kinoshita M. Coronary effects of diadenosine tetraphosphate resemble those of adenosine in anesthetized pigs: Involvement of ATP-sensitive potassium channels. J. Cardiovasc. Pharmacol. 28:1996;124-133.
    • (1996) J. Cardiovasc. Pharmacol. , vol.28 , pp. 124-133
    • Nakae, I.1    Takahashi, M.2    Takaoka, A.3    Liu, Q.4    Matsumoto, T.5    Amano, M.6    Sekine, A.7    Nakajima, H.8    Kinoshita, M.9
  • 32
    • 0029108913 scopus 로고
    • Physiological roles and properties of potassium channels in arterial smooth muscle
    • Nelson M.T., Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268:1995;C799-C822.
    • (1995) Am. J. Physiol. , vol.268
    • Nelson, M.T.1    Quayle, J.M.2
  • 34
    • 0029609859 scopus 로고
    • Will calcium sensitizers play a role in the treatment of heart failure?
    • Nielsen-Kudsk J.E., Aldershvile J. Will calcium sensitizers play a role in the treatment of heart failure? J. Cardiovasc. Pharmacol. 26 (Suppl. 1):1995;S77-S84.
    • (1995) J. Cardiovasc. Pharmacol. , vol.261
    • Nielsen-Kudsk, J.E.1    Aldershvile, J.2
  • 35
    • 0024531967 scopus 로고
    • ATP regulation of the slow calcium channels in vascular smooth muscle cells of guinea pig mesenteric artery
    • Ohya Y., Sperelakis N. ATP regulation of the slow calcium channels in vascular smooth muscle cells of guinea pig mesenteric artery. Circ. Res. 64:1989;145-154.
    • (1989) Circ. Res. , vol.64 , pp. 145-154
    • Ohya, Y.1    Sperelakis, N.2
  • 36
    • 0345669398 scopus 로고
    • Modulation of single slow (L-type) calcium channels by intracellular ATP in vascular smooth muscle cells
    • Ohya Y., Sperelakis N. Modulation of single slow (L-type) calcium channels by intracellular ATP in vascular smooth muscle cells. Pflugers Arch. 414:1989;257-264.
    • (1989) Pflugers Arch. , vol.414 , pp. 257-264
    • Ohya, Y.1    Sperelakis, N.2
  • 37
    • 0023723794 scopus 로고
    • Vasodilator and inotropic drugs for the treatment of chronic heart failure: Distinguishing hype from hope
    • Packer M. Vasodilator and inotropic drugs for the treatment of chronic heart failure: Distinguishing hype from hope. J. Am. Coll. Cardiol. 12:1988;1299-1317.
    • (1988) J. Am. Coll. Cardiol. , vol.12 , pp. 1299-1317
    • Packer, M.1
  • 38
    • 0028826965 scopus 로고
    • Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs
    • Pagel P.S., Harkin C.P., Hettrick D.A., Warltier D.C. Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs. J. Pharmacol. Exp. Ther. 275:1995;127-135.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 127-135
    • Pagel, P.S.1    Harkin, C.P.2    Hettrick, D.A.3    Warltier, D.C.4
  • 39
    • 0027536321 scopus 로고
    • + channels in vascular smooth muscle cells of the guinea pig portal vein
    • + channels in vascular smooth muscle cells of the guinea pig portal vein. Pfluger Arch. 423:1993;149-151.
    • (1993) Pfluger Arch. , vol.423 , pp. 149-151
    • Pfrunder, D.1    Anghelescu, I.2    Kreye, V.A.W.3
  • 41
    • 85047679339 scopus 로고
    • Cellular pharmacology of potassium channel openers in vascular smooth muscle
    • Quast U., Guillon J.-M., Cavero I. Cellular pharmacology of potassium channel openers in vascular smooth muscle. Cardiovasc. Res. 28:1994;805-810.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 805-810
    • Quast, U.1    Guillon, J.-M.2    Cavero, I.3
  • 44
    • 0026741427 scopus 로고
    • ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo
    • Samaha F.F., Heineman F.W., Ince C., Fleming J., Baraban R.S. ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo. Am. J. Physiol. 262:1992;C1220-C1227.
    • (1992) Am. J. Physiol. , vol.262
    • Samaha, F.F.1    Heineman, F.W.2    Ince, C.3    Fleming, J.4    Baraban, R.S.5
  • 45
    • 0026759418 scopus 로고
    • + channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents
    • + channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents. J. Gen. Physiol. 100:1992;573-591.
    • (1992) J. Gen. Physiol. , vol.100 , pp. 573-591
    • Sheppard, D.N.1    Welsh, M.J.2
  • 47
    • 0029038397 scopus 로고
    • Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men
    • Sundberg S., Lilleberg J., Nieminen M.S., Lehtonen L. Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men. Am. J. Cardiol. 75:1995;1061-1066.
    • (1995) Am. J. Cardiol. , vol.75 , pp. 1061-1066
    • Sundberg, S.1    Lilleberg, J.2    Nieminen, M.S.3    Lehtonen, L.4
  • 49
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N. Engl. J. Med. 316:1987;1429-1435.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 1429-1435
    • The Consensus Trial Study Group1
  • 50
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N. Engl. J. Med. 325:1991;293-302.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 293-302
    • The Solvd Investigators1
  • 52
    • 0028908851 scopus 로고
    • Cardiovascular effects of the calcium sensitizer, levosimendan, in heart failure induced by rapid pacing in the presence of aortic constriction
    • Udvary E., Papp J.G., Vegh A. Cardiovascular effects of the calcium sensitizer, levosimendan, in heart failure induced by rapid pacing in the presence of aortic constriction. Br. J. Pharmacol. 114:1995;656-661.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 656-661
    • Udvary, E.1    Papp, J.G.2    Vegh, A.3
  • 54
    • 0031001828 scopus 로고    scopus 로고
    • + currents in smooth muscle cells of intact rat small arteries
    • + currents in smooth muscle cells of intact rat small arteries. J. Physiol. London. 500:1997;617-630.
    • (1997) J. Physiol. London , vol.500 , pp. 617-630
    • Weidelt, T.1    Boldt, W.2    Markwardt, F.3
  • 55
    • 0031066156 scopus 로고    scopus 로고
    • 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery
    • 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery. Am. J. Physiol. 272:1997;H814-H819.
    • (1997) Am. J. Physiol. , vol.272
    • Yokoshiki, H.1    Katsube, Y.2    Sperelakis, N.3
  • 57
    • 0029145956 scopus 로고
    • i in pulmonary arterial myocytes
    • i in pulmonary arterial myocytes. Circ. Res. 77:1995;370-378.
    • (1995) Circ. Res. , vol.77 , pp. 370-378
    • Yuan, X.-J.1
  • 58
    • 0028926379 scopus 로고
    • Activation by intracellular GDP, metabolic inhibition and pinacidil of a glibenclamide-sensitive K-channel in smooth muscle cells of rat mesenteric artery
    • Zhang H., Bolton T.B. Activation by intracellular GDP, metabolic inhibition and pinacidil of a glibenclamide-sensitive K-channel in smooth muscle cells of rat mesenteric artery. Br. J. Pharmacol. 114:1995;662-672.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 662-672
    • Zhang, H.1    Bolton, T.B.2
  • 59
    • 0029924673 scopus 로고    scopus 로고
    • Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells
    • Zhang H.-L., Bolton T.B. Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells. Br. J. Pharmacol. 118:1996;105-114.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 105-114
    • Zhang, H.-L.1    Bolton, T.B.2


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