Synthesis and evaluation of novel diphenylthiazole derivatives as potential anti-inflammatory agents

Medicinal Chemistry Research

Volumn 24, Issue 10, 2015, Pages 3681-3695

  Abdelazeem, Ahmed H ^a   Habash, Maha ^b   Maghrabi, Ibrahim A ^c   Taha, Mutasem O ^d  

^a Beni Suef University   (Egypt)

^b APPLIED SCIENCE PRIVATE UNIVERSITY   (Jordan)

^c TAIF UNIVERSITY   (Saudi Arabia)

^d UNIVERSITY OF JORDAN   (Jordan)

Author keywords

Anti inflammatory; Diphenylthiazole; Docking; Inflamed animal paws

Indexed keywords

1 (4,5 DIPHENYLTHIAZOL 2 YL) 3 HEXYLUREA; 1 (4,5 DIPHENYLTHIAZOL 2 YL) 3 TETRADECYLUREA; 1 (BENZO[D]THIAZOL 2 YL) 3 (4,5 DIPHENYLTHIAZOL 2 YL)UREA; 1 CYCLOHEXYL 3 (4,5 DIPHENYLTHIAZOL 2 YL)UREA; 1 DECYL 3 (4,5 DIPHENYLTHIAZOL 2 YL)UREA; 1(ADAMANTAN 2 YL) 3 (4,5 DIPHENYLTHIAZOL 2 YL)UREA; 2 (ADAMANTAN 2 YLAMINO) N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; 2 (BENZO[D]THIAZOL 2 YLAMINO) N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; 2 (BENZO[D]THIAZOL 2 YLTHIO) N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; 2 (BENZYLOXY) N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; 2 (DECYLAMINO) N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; 2 CHLORO N (4,5 DIPHENYLTHIAZOL 2 YL)ACETAMIDE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1 INHIBITOR; DIPHENYLTHIAZOLE DERIVATIVE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 (HEXYLAMINO)ACETAMIDE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 (OCTYLAMINO)ACETAMIDE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 (PIPERIDIN 1 YL)ACETAMIDE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 (TETRADECYLAMINO)ACETAMIDE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 (THIAZOL 2 YLAMINO)ACETAMIDE; N (4,5 DIPHENYLTHIAZOL 2 YL) 2 [[2 (NAPHTHALEN 1 YLAMINO) ETHYL]AMINO]ACETAMIDE; S BENZO[D]THIAZOL 2 YL (4,5 DIPHENYLTHIAZOL 2 YL)CARBAMOTHIOATE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARRAGEENAN-INDUCED PAW EDEMA; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HYDROGEN BOND; IN VIVO STUDY; MALE; MOLECULAR DOCKING; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

EID: 84940612791     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-015-1418-5     Document Type: Article

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