Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 34, 2015, Pages 10685-10690

  Kaya, Alaattin ^a   Gerashchenko, Maxim V ^a   Seim, Inge ^a   Labarre, Jean ^b   Toledano, Michel B ^b   Gladyshev, Vadim N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DIF   (France)

Author keywords

Aneuploidy; Oxidative stress; Respiration; Thiol peroxidase

Indexed keywords

CYTOCHROME C PEROXIDASE; HYDROGEN PEROXIDE; MITOCHONDRIAL PROTEIN; PEROXIDASE; THIOL; ANTIMYCIN A1; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; OLIGOMYCIN; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; ROTENONE; SACCHAROMYCES CEREVISIAE PROTEIN; SRX1 PROTEIN, S CEREVISIAE; UTH1 PROTEIN, S CEREVISIAE;

ANEUPLOIDY; ARTICLE; BREATHING; CELL GROWTH; CELL SURVIVAL; CELLULAR DISTRIBUTION; CHROMOSOME 11; CONTROLLED STUDY; ENZYME DEFICIENCY; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; YEAST CELL; ADAPTATION; CHROMOSOME; CHROMOSOME DELETION; DEFICIENCY; DRUG EFFECTS; ELECTRON TRANSPORT; ENZYMOLOGY; FUNGAL GENE; GENE DOSAGE; GENETICS; METABOLISM; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

ADAPTATION, PHYSIOLOGICAL; ANEUPLOIDY; ANTIMYCIN A; CHROMOSOME DELETION; CHROMOSOMES, FUNGAL; CYTOCHROME-C PEROXIDASE; ELECTRON TRANSPORT; GENE DELETION; GENE DOSAGE; GENES, FUNGAL; HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; MEMBRANE PROTEINS; MITOCHONDRIAL PROTEINS; OLIGOMYCINS; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PEROXIDASES; REACTIVE OXYGEN SPECIES; ROTENONE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84940522652     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1505315112     Document Type: Article

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