Repair of spinal cord injury by chitosan scaffold with glioma ECM and SB216763 implantation in adult rats

Journal of Biomedical Materials Research - Part A

Volumn 103, Issue 10, 2015, Pages 3259-3272

  Rao, Jian ^a   Yang, Yixu ^a   Lin, Sheyu ^a   Shen, Jianhong ^a   Yan, Yaohua ^a   Su, Xing ^a   Huang, Qingfeng ^a   Lu, Xiaojian ^a   Zhang, Lei ^a   Zhen, Yan ^a   Xiong, Fangling ^a   Gao, Huasong ^b   Gao, Yilu ^a  

^a NANTONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

ECM; neural stem cells; SB216763; SCI

Indexed keywords

BIOCOMPATIBILITY; CELLS; CHITIN; CHITOSAN; CYTOLOGY; ELECTROPHYSIOLOGY; MILITARY ELECTRONIC COUNTERMEASURES; NEURONS; PATIENT REHABILITATION; REPAIR; STEM CELLS;

CHITOSAN SCAFFOLD; GOOD COMPATIBILITY; INJURED SPINAL CORDS; NEURAL STEM CELL; OLIGODENDROCYTES; SB216763; SCI; SPINAL CORD INJURIES (SCI);

SCAFFOLDS (BIOLOGY);

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; CHITOSAN; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BIOCOMPATIBILITY; BLOOD BRAIN BARRIER; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROPHYSIOLOGY; EVALUATION STUDY; EXTRACELLULAR MATRIX; FEMALE; FREEZE DRYING; FREEZE THAWING; GLIOMA; GLIOMA CELL; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; LATENT PERIOD; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; RAT; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; ANIMAL; CHEMISTRY; METABOLISM; PATHOLOGY; SPINAL CORD INJURIES; SPRAGUE DAWLEY RAT; TISSUE SCAFFOLD; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHITOSAN; GLIOMA; INDOLES; MALEIMIDES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; TISSUE SCAFFOLDS;

EID: 84940462619     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35466     Document Type: Article

References (28)

1. Bozkurt G, Mothe AJ, Zahir T, Kim H, Shoichet MS, Tator CH,. Chitosan channels containing spinal cord-derived stem/progenitor cells for repair of subacute spinal cord injury in the rat. Neurosurgery 2010; 67: 1733-1744.
2. Zheng L, Cui HF,. Use of chitosan conduit combined with bone marrow mesenchymal stem cells for promoting peripheral nerve regeneration. J Mater Sci Mater Med 2010; 21: 1713-1720.
3. Narayanan K, Leck KJ, Gao S, Wan AC,. Three-dimensional reconstituted extracellular matrix scaffolds for tissue engineering. Biomaterials 2009; 30: 4309-4317.
4. Lange C, Mix E, Frahm J, Glass A, Muller J, Schmitt O, Schmole AC, Klemm K, Ortinau S, Hubner R, Frech MJ, Wree A, Rolfs A,. Small molecule GSK-3 inhibitors increase neurogenesis of human neural progenitor cells. Neurosci Lett 2011; 488: 36-40.
5. Barton-Pai A, Feleder C, Johnson A,. Tumor necrosis factor-alpha induces increased lung vascular permeability: A role for GSK3alpha/beta. Eur J Pharmacol 2011; 657: 159-166.
6. Xia Y-X, Lu L, Wu Z-S, Pu L-Y, Sun B-C, Wang X-H,. Inhibition of GSK-3β ameliorates hepatic ischemia-reperfusion injury through GSK-3β/β-catenin signaling pathway in mice. Hepatobiliary Pancreat Dis Int 2012; 11: 278-284.
7. Lu H, Hoshiba T, Kawazoe N, Chen G,. Comparison of decellularization techniques for preparation of extracellular matrix scaffolds derived from three-dimensional cell culture. J Biomed Mater Res A 2012; 100: 2507-2516.
8. Tuszynski MH, Steward O,. Concepts and methods for the study of axonal regeneration in the CNS. Neuron 2012; 74: 777-791.
9. Nakamura M, Okano H,. Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells. Cell Res 2013; 23: 70-80.
10. Mothe AJ, Tam RY, Zahir T, Tator CH, Shoichet MS,. Repair of the injured spinal cord by transplantation of neural stem cells in a hyaluronan-based hydrogel. Biomaterials 2013; 34: 3775-3783.
11. Nishimura S, Yasuda A, Iwai H, Takano M, Kobayashi Y, Nori S, Tsuji O, Fujiyoshi K, Ebise H, Toyama Y, Okano H, Nakamura M,. Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury. Mol Brain 2013; 6: 3
12. Saglam A, Perets A, Canver AC, Li HL, Kollins K, Cohen G, Fischer I, Lazarovici P, Lelkes PI,. Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair. J Mol Neurosci 2013; 49: 334-346.
13. Jha RM, Liu X, Chrenek R, Madsen JR, Cardozo DL., The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons. Neurosurgery 2013; 72: 118-129; discussion 129.
14. Shimada H, Okada Y, Ibata K, Ebise H, Ota S, Tomioka I, Nomura T, Maeda T, Kohda K, Yuzaki M, Sasaki E, Nakamura M, Okano H,. Efficient derivation of multipotent neural stem/progenitor cells from non-human primate embryonic stem cells. PLoS One 2012; 7: e49469
15. Turgeman G, Pinkas A, Slotkin TA, Tfilin M, Langford R, Yanai J,. Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells. J Neurosci Res 2011; 89: 1185-1193.
16. Ishino Y, Hayashi Y, Naruse M, Tomita K, Sanbo M, Fuchigami T, Fujiki R, Hirose K, Toyooka Y, Fujimori T, Ikenaka K, Hitoshi S,. Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells. J Neurosci 2014; 34: 3067-3078.
17. Franze K, Janmey PA, Guck J,. Mechanics in neuronal development and repair. Annu Rev Biomed Eng 2013; 15: 227-251.
18. Noh MY, Chun K, Kang BY, Kim H, Park JS, Lee HC, Kim YH, Ku S, Kim SH,. Newly developed glycogen synthase kinase-3 (GSK-3) inhibitors protect neuronal cells death in amyloid-beta induced cell model and in a transgenic mouse model of Alzheimer's disease. Biochem Biophys Res Commun 2013; 435: 274-281.
19. Fuster-Matanzo A, Llorens-Martin M, Sirerol-Piquer MS, Garcia-Verdugo JM, Avila J, Hernandez F,. Dual effects of increased glycogen synthase kinase-3beta activity on adult neurogenesis. Hum Mol Genet 2013; 22: 1300-1315.
20. Eroglu H, Nemutlu E, Turkoglu OF, Nacar O, Bodur E, Sargon MF, Beskonakli E, Oner L,. A quadruped study on chitosan microspheres containing atorvastatin calcium: preparation, characterization, quantification and in-vivo application. Chem Pharm Bull (Tokyo) 2010; 58: 1161-1167.
21. Kim H, Tator CH, Shoichet MS,. Chitosan implants in the rat spinal cord: biocompatibility and biodegradation. J Biomed Mater Res A 2011; 97: 395-404.
22. Ragetly GR, Griffon DJ, Lee HB, Chung YS,. Effect of collagen II coating on mesenchymal stem cell adhesion on chitosan and on reacetylated chitosan fibrous scaffolds. J Mater Sci Mater Med 2010; 21: 2479-2490.
23. Huang YC, Liu TJ,. Mobilization of mesenchymal stem cells by stromal cell-derived factor-1 released from chitosan/tripolyphosphate/fucoidan nanoparticles. Acta Biomater 2012; 8: 1048-1056.
24. Bhardwaj N, Kundu SC,. Chondrogenic differentiation of rat MSCs on porous scaffolds of silk fibroin/chitosan blends. Biomaterials 2012; 33: 2848-2857.
25. Wang Q, Jamal S, Detamore MS, Berkland C,. PLGA-chitosan/PLGA-alginate nanoparticle blends as biodegradable colloidal gels for seeding human umbilical cord mesenchymal stem cells. J Biomed Mater Res A 2011; 96: 520-527.
26. Mathews S, Bhonde R, Gupta PK, Totey S,. A novel tripolymer coating demonstrating the synergistic effect of chitosan, collagen type 1 and hyaluronic acid on osteogenic differentiation of human bone marrow derived mesenchymal stem cells. Biochem Biophys Res Commun 2011; 414: 270-276.
27. Leipzig ND, Wylie RG, Kim H, Shoichet MS,. Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds. Biomaterials 2011; 32: 57-64.
28. Cho Y, Shi R, Borgens RB,. Chitosan produces potent neuroprotection and physiological recovery following traumatic spinal cord injury. J Exp Biol 2010; 213: 1513-1520.