Stroke-Like Episodes Heralding a Reversible Encephalopathy: Microbleeds as the Key to the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation - A Case Report and Literature Review

Journal of Stroke and Cerebrovascular Diseases

Volumn 24, Issue 9, 2015, Pages e245-e250

  Mendonça, Marcelo D ^a,b   Caetano, André ^a   Pinto, Miguel ^a   Cruz E Silva, Vera ^a   Viana Baptista, Miguel ^a,b  

^a HOSPITAL EGAS MONIZ   (Portugal)

^b NOVA MEDICAL SCHOOL   (Portugal)

Author keywords

cerebral amyloid angiopathy; cerebral amyloid angiopathy related inflammation; microbleeds; Stroke

Indexed keywords

ACICLOVIR; ALPRAZOLAM; ALTIZIDE; APOENZYME; BISOPROLOL; BROTIZOLAM; DOMPERIDONE; FLUINDOSTATIN; LEVOTHYROXINE; METHYLPREDNISOLONE; PREDNISOLONE; SPIRONOLACTONE;

AGED; BRAIN HEMORRHAGE; CASE REPORT; CEREBRAL AMYLOID ANGIOPATHY RELATED INFLAMMATION; CEREBROSPINAL FLUID ANALYSIS; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; EARLY DIAGNOSIS; ELECTROENCEPHALOGRAM; ENCEPHALITIS; FEMALE; GENOTYPE; HUMAN; LYMPHOCYTE COUNT; MENTAL DETERIORATION; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVIEW; STEROID THERAPY; VASCULAR AMYLOIDOSIS; VIRUS ENCEPHALITIS; WHITE MATTER LESION; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL HEMORRHAGE; COMPLICATION; INFLAMMATION; PATHOPHYSIOLOGY;

AGED; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL HEMORRHAGE; FEMALE; HUMANS; INFLAMMATION; MAGNETIC RESONANCE IMAGING; STROKE;

EID: 84940462388     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2015.04.042     Document Type: Article

References (50)

1. K.A. Knudsen, J. Rosand, D. Karluk, and et al. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria Neurology 56 2001 537 539
2. C. Kinnecom, M.H. Lev, L. Wendell, and et al. Course of cerebral amyloid angiopathy-related inflammation Neurology 68 2007 1411 1416
3. K.K. Chung, N.E. Anderson, D. Hutchinson, and et al. Cerebral amyloid angiopathy related inflammation: three case reports and a review J Neurol Neurosurg Psychiatry 82 2011 20 26
4. C. Salvarani, G.G. Hunder, J.M. Morris, and et al. Aβ-related angiitis: comparison with CAA without inflammation and primary CNS vasculitis Neurology 81 2013 1596 1603
5. M. Martucci, S. Sarria, M. Toledo, and et al. Cerebral amyloid angiopathy-related inflammation: imaging findings and clinical outcome Neuroradiology 56 2014 283 289
6. F. Piazza, S.M. Greenberg, M. Savoiardo, and et al. Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies Ann Neurol 73 2013 449 458
7. N.J. Scolding, F. Joseph, P.A. Kirby, and et al. A beta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy Brain 128 Pt 3 2005 500 515
8. A.R. Cenina, J. De Leon, K.Y. Tay, and et al. Cerebral amyloid angiopathy-related inflammation presenting with rapidly progressive dementia, responsive to IVIg Alzheimer Dis Assoc Disord 2015 [Epub ahead of print]
9. G.B. Boncoraglio, F. Piazza, M. Savoiardo, and et al. Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-aβ autoantibodies J Alzheimers Dis 45 2015 363 367
10. N.S. Ryan, T. Lashley, T. Revesz, and et al. Spontaneous ARIA (amyloid-related imaging abnormalities) and cerebral amyloid angiopathy related inflammation in presenilin 1-associated familial Alzheimer's disease J Alzheimers Dis 44 2015 1069 1074
11. 11C-PiB PET imaging of encephalopathy associated with cerebral amyloid angiopathy Intern Med 53 2014 1997 2000
12. A.L. Berkowitz, J.M. Baker, J.J. Miller, and et al. Mystery case: cerebral amyloid angiopathy-related inflammation Neurology 83 2014 1678 1679
13. M. Ishii, E. Lavi, H. Kamel, and et al. Amyloid β-related central nervous system angiitis presenting with an isolated seizure Neurohospitalist 4 2014 86 89
14. A. Danve, M. Grafe, and A. Deodhar Amyloid beta-related angiitis - a case report and comprehensive review of literature of 94 cases Semin Arthritis Rheum 44 2014 86 92
15. A. Nouh, E. Borys, A.K. Gierut, and et al. Amyloid-beta related angiitis of the central nervous system: case report and topic review Front Neurol 5 2014 13
16. Y. Hagiwara, T. Yanagisawa, C. Atsumi, and et al. A case report of cerebral amyloid angiopathy-related inflammation treated with cyclophosphamide Rinsho Shinkeigaku 54 2014 46 51
17. N.D. Child, S.A. Braksick, E.P. Flanagan, and et al. Amyloid-β-related angiitis presenting as a uveomeningeal syndrome Neurology 81 2013 1796 1798
18. L. Chamard, D. Wallon, A. Pijoff, and et al. Amyloid-related imaging abnormalities in AβPP duplication carriers J Alzheimers Dis 37 2013 789 793
19. M. Porter, C.R. Newey, and G. Toth Teaching NeuroImages: treatment-resistant rapidly progressive amyloid β-related angiitis Neurology 80 2013 e187 e188
20. A. Omisade, H. Rigby, A. Easton, and et al. Longitudinal neuropsychological findings in amyloid beta-related angiitis (AβRA): a case report Clin Neuropsychol 27 2013 300 312
21. A. Kimura, T. Sakurai, N. Yoshikura, and et al. Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation J Neuroinflammation 10 2013 39
22. P. de la Riva, F. Moreno, N. Carrera, and et al. Response to treatment with corticoids in a case of inflammatory amyloid angiopathy without performing a biopsy Rev Neurol 55 2012 408 412
23. T. Iwanaga, N. Kaneko, H. Nishimura, and et al. Cerebral amyloid angiopathy-related leukodystrophy: a case report Rinsho Shinkeigaku 52 2012 585 588
24. S.A. Weiss, D. Pisapia, S.A. Mayer, and et al. Amyloid β-related angiitis causing coma responsive to immunosuppression Case Rep Pathol 2012 2012 678746
25. O. Wengert, L. Harms, and E. Siebert Cerebral amyloid angiopathy-related inflammation: a treatable cause of rapidly-progressive dementia J Neuropsychiatry Clin Neurosci 24 2012 E1 E2
26. N. Melzer, A. Harder, C.C. Gross, and et al. CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis Arch Neurol 69 2012 773 777
27. K. Machida, A. Tsuchiya-Suzuki, and et al. Postmortem findings in a patient with cerebral amyloid angiopathy actively treated with corticosteroid Amyloid 19 2012 47 52
28. K. Sakai, S. Hayashi, K. Sanpei, and et al. Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy-related inflammation Neuropathology 32 2012 551 556
29. M. Kurian, K. Burkhardt, F. Assal, and et al. Amyloid plaques and intraneuronal tau inclusions in A-beta-related angiitis (ABRA) Neuropathol Appl Neurobiol 38 2012 391 394
30. H. Sakaguchi, A. Ueda, T. Kosaka, and et al. Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: case report and review of the literature J Neuroinflammation 8 2011 116
31. A. Makol, J.E. Parisi, G.W. Petty, and et al. A 60-year-old woman with headache, confusion, and hallucinations Arthritis Care Res (Hoboken) 63 2011 1486 1494
32. D.M. Hermann, K. Keyvani, J. van de Nes, and et al. Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy Neurology 77 2011 503 505
33. H. Rigby, A. Easton, and V. Bhan Amyloid β-related angiitis of the central nervous system: report of 3 cases Can J Neurol Sci 38 2011 626 630
34. S.I. Bekkelund, C.E. Midtbu, L. Arvola, and et al. Good outcome in a patient treated for cerebral amyloid angiopathy presenting as an expansive process with inflammation and contrast enhancement AJNR Am J Neuroradiol 32 2011 E75
35. R.A. Bernstein, M. Gibbs, and H. Hunt Batjer Clinical diagnosis and successful treatment of inflammatory cerebral amyloid angiopathy Neurocrit Care 14 2011 453 455
36. J.C. DiFrancesco, M. Brioschi, L. Brighina, and et al. Anti-Aβ autoantibodies in the CSF of a patient with CAA-related inflammation: a case report Neurology 76 2011 842 844
37. M. Savoiardo, A. Erbetta, G. Storchi, and et al. Case 159: cerebral amyloid angiopathy-related inflammation Radiology 256 2010 323 327
38. M. Morishige, T. Abe, T. Kamida, and et al. Cerebral vasculitis associated with amyloid angiopathy: case report Neurol Med Chir (Tokyo) 50 2010 336 338
39. R.P. Kloppenborg, E. Richard, M.E. Sprengers, and et al. Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment J Neuroinflammation 7 2010 18
40. H.J. Tschampa, P. Niehusmann, M. Marek, and et al. MRI in amyloid beta-related brain angiitis Neurology 73 2009 247
41. R. Daniëls, J.J. Geurts, J.C. Bot, and et al. Steroid-responsive edema in CAA-related inflammation J Neurol 256 2009 285 286
42. R.N. Alcalay, and E.E. Smith MRI showing white matter lesions and multiple lobar microbleeds in a patient with reversible encephalopathy J Neuroimaging 19 2009 89 91
43. A. Amick, J. Joseph, N. Silvestri, and et al. Amyloid-beta-related angiitis: a rare cause of recurrent transient neurological symptoms Nat Clin Pract Neurol 4 2008 279 283
44. K. Machida, K. Tojo, K.S. Naito, and et al. Cortical petechial hemorrhage, subarachnoid hemorrhage and corticosteroid-responsive leukoencephalopathy in a patient with cerebral amyloid angiopathy Amyloid 15 2008 60 64
45. U. Oh, R. Gupta, J.W. Krakauer, and et al. Reversible leukoencephalopathy associated with cerebral amyloid angiopathy Neurology 62 2010 494 497
46. J.A. Eng, M.P. Frosch, K. Choi, and et al. Clinical manifestations of cerebral amyloid angiopathy-related inflammation Ann Neurol 55 2004 250 256
47. K.A. Harkness, A. Coles, U. Pohl, and et al. Rapidly reversible dementia in cerebral amyloid inflammatory vasculopathy Eur J Neurol 11 2004 59 62
48. S.H. Wong, P.D. Robbins, N.W. Knuckey, and et al. Cerebral amyloid angiopathy presenting with vasculitic pathology J Clin Neurosci 13 2006 291 294
49. M. Savoiardo, A. Erbetta, J.C. Di Francesco, and et al. Cerebral amyloid angiopathy-related inflammation: an emerging disease Neuroradiol J 24 2011 253 257
50. M. Margaglione, D. Seripa, C. Gravina, and et al. Prevalence of apolipoprotein E alleles in healthy subjects and survivors of ischemic stroke: an Italian case-control study Stroke 29 1998 399 403